EXPORT CITATION

Chapter-007 The Stem Cells in Orthopedic Surgery

BOOK TITLE: Textbook of Orthopedics & Trauma (4 Volumes)

Author
1. Arora Anil
2. Agarwal Anil
3. Chadha Manish
ISBN
9789385891052
DOI
10.5005/jp/books/12869_8
Edition
3/e
Publishing Year
2016
Pages
5
Author Affiliations
1. Max Hospital; University College of Medical Sciences and GTB Hospital, Delhi, India, University College of Medical Sciences, New Delhi, Max Superspecialty Hospital, Delhi, India, Ganga Ram Institute for Postgraduate Medical Education and Research, Sir Ganga Ram Hospital, New Delhi, India, University College of Medical Sciences, Delhi, India, School of Medical Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India, Sir Ganga Ram Hospital, New Delhi, India
2. Chacha Nehru Bal Chikitsalaya, Delhi, India, Fortis Hospital, Noida, Uttar Pradesh, India, School of Medical Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India, All India Institute of Medical Sciences, New Delhi, India, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, Uttar Pradesh, India, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, 131, Ankur Apartment, 7, IP Extension, Parparganj, New Delhi, Chacha Nehru Bal Chikitsalya, Geeta Colony, Delhi
3. C-A/16 Tagore Garden, New Delhi, University College of Medical Sciences, New Delhi, India, Bharati Vidyapeeth Deemed University, Medical College and Hospital, Sangli, Maharashtra, India
Chapter keywords
stem cell, orthopedic surgery, embryonic stem cell, adult stem cell, spinal fusion, osteogenesis imperfecta, ACI

Abstract

This chapter discusses the stem cells in orthopedic surgery. A stem cell is an immature or undifferentiated cell which is capable of producing an identical daughter cell. Stem cells have the unique capacity to remain dormant or lie quiescent for prolonged periods until they are exposed to an external stimulus. They are classified into totipotent, capable of forming any tissue (e.g. fertilized egg or zygote); pluripotent, with less differentiating capacity compared to totipotent (e.g. embryonic stem cells); and multipotent, which are capable of differentiating into one particular cell lineage only, e.g. bone marrow stromal or mesenchymal stem cells. Sources of stem cell are embryonic stem cells and adult stem cells. Approaches to tissue reconstruction based on use of stem cells have opened up wide potential applications. Various techniques like filtration, culture expansion, and sieving are being employed for concentration purpose.

Related Books

© 2019 Jaypee Brothers Medical Publishers (P) LTD.   |   All Rights Reserved