This chapter discusses injuries of peripheral nerve. Spinal nerves are composite neural entities containing motor, sensory as well as autonomic fibers. In keeping with the symmetrical, segmental origins of the human form, we have spinal nerves corresponding to each segment coming out bilaterally from the spinal cord. The central nervous system develops from the neural tube, while the peripheral nervous system arises from the neural crest cells in the ectoderm. In this chapter, emphasis is given on the spinal nerves since their disorders are mainly treated by the reconstructive and/or orthopedic surgeons. Nerve injuries occur either as isolated injuries or more commonly as part of a larger composite limb injury. Classification of injury and technique of nerve repair are also discussed in this chapter.