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Chapter-10 Drugs for the Heart

BOOK TITLE: Practical Cardiology

Author
1. Khan M Gabriel
ISBN
9789386056016
DOI
10.5005/jp/books/18060_11
Edition
1/e
Publishing Year
2018
Pages
14
Author Affiliations
1. University of Ottawa; The Ottawa Hospital, Ottawa, Ontario, Canada
Chapter keywords
Heart failure, acute myocardial infarction, hypertension, atrial fibrillation, diabetes, arrhythmias, diuretic therapy, beta-blockers, warfarin, digoxin, aspirin

Abstract

This chapter describes the drugs for the heart, which include drugs for heart failure, drugs for acute myocardial infarction, drugs for hypertension, drugs for atrial fibrillation, drugs for diabetes, and arrhythmias. Diuretic therapy remains a mainstay for the relief of distressing shortness of breath (SOB) and edema. Various drugs that are used for the management of postmyocardial infarction are beta-blockers, aspirin, clopidogrel, statins, streptokinase, and angiotensin converting enzyme inhibitors. Drugs for atrial fibrillation are digoxin, beta-blockers, warfarin, renoprotection, apixaban, dabigatran, and rivaroxaban. Digoxin remains most useful most often in combination with a small dose of a beta-blocking drug. Digoxin use is frowned upon and use has fallen drastically in the past 20 years mainly because of fear of toxicity and failure to reduce rapid rates more than 130 beats/min or on exercise.

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