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Chapter-20 Medicinal Supplements

BOOK TITLE: Practical Cardiology

Author
1. Khan M Gabriel
ISBN
9789386056016
DOI
10.5005/jp/books/18060_21
Edition
1/e
Publishing Year
2018
Pages
6
Author Affiliations
1. University of Ottawa; The Ottawa Hospital, Ottawa, Ontario, Canada
Chapter keywords
Medical supplement, cardiovascular effect, cardiac drug, cocoa, garlic, coenzyme Q10, ginseng, Chinese red yeast rice, calcium supplement

Abstract

This chapter deals with medical supplements that are believed by some to have at least modest beneficial cardiovascular effects. Several herbal remedies and supplements are used by more than 2 billion individuals in hope of a cure or amelioration of a disorder that responds partially to prescribed medicines. Some of the many herbal remedies consumed particularly by Asians are cardiotoxic or interact with cardiac drugs. Warnings about nephrotoxic and other toxic and carcinogenic effects associated with products containing kava, comfrey, and aristolochic were instituted by the Food and Drug Administration. This chapter covers the cocoa, garlic, coenzyme Q10, ginseng, Chinese red yeast rice, and calcium supplements. In a pooled analysis of approximately 12,000 participants from 11 randomized controlled trials, calcium supplements were associated with about a 30% increase in the incidence of myocardial infarction.

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