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Chapter-25 Transplant Pathology

BOOK TITLE: Liver Biopsy Made Easy

Author
1. Gupta Nalini Bansal
2. Bihari Chhagan
ISBN
9789386150264
DOI
10.5005/jp/books/14215_26
Edition
1/e
Publishing Year
2018
Pages
24
Author Affiliations
1. SRL Ltd, Fortis Escorts Heart Institute, New Delhi, India
2. Institute of Liver and Biliary Sciences, New Delhi, India
Chapter keywords
Transplant pathology, protocol liver biopsy, indicated liver biopsy, liver function test, liver transplant rejection, opportunistic infection, vascular complication, plasma cell hepatitis

Abstract

This chapter describes transplant pathology. Types of transplant pathology are protocol liver biopsy and indicated liver biopsy. Protocol liver biopsy is done according to guidelines rather than in response to the patient’s clinical status. It includes early and late biopsies. Early protocol biopsy is usually performed 7 days after transplantation because liver function tests are insufficient for the diagnosis and assessment of severity of rejection. Late protocol biopsies are performed after 6 months of transplant. This chapter covers the spectrum of diseases seen in post-transplant liver biopsies, differentials as per timing of biopsy, liver transplant rejection, recurrence of primary diseases, post-transplant lymphoproliferative disorder, opportunistic infections, vascular complications, biliary tract complication, and plasma cell hepatitis.

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