This chapter discusses about the male pelvic pain. Male pelvic pain can include a wide variety of pain generators, which can be challenging for a clinician to identify and treat. For chronic male pelvic pain conditions, lifetime prevalence has been reported to be 2–14%. Often, diagnosis can be vague and requires consideration of the musculoskeletal, neurological, psychological, and genitourinary systems. For many conditions, diagnosis is obtained by exclusion and requires an experienced clinician to perform a relevant, yet thorough history and physical examination. Successful treatment is difficult and may include stress reduction, diet modification, pelvic floor physical therapy, amitriptyline, hydrodistention, and sacral or pudendal neuromodulation. Treating the male pelvic pain patient should involve a multidisciplinary approach and is usually a lengthy process.