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Chapter-19 Viral Infections (Systemic)

BOOK TITLE: Concise Handbook of Infectious Diseases

Author
1. Sahadulla MI
ISBN
9789386261939
DOI
10.5005/jp/books/14120_20
Edition
1/e
Publishing Year
2018
Pages
37
Author Affiliations
1. Kerala Institute of Medical Sciences (KIMS) Healthcare Group, Thiruvananthapuram, Kerala, India
Chapter keywords
Viral Infection, rubella, influenza virus, respiratory syncytial virus, hepatotrophic virus, herpes simplex virus, varicella-zoster virus, Ebola, human immunodeficiency virus, acquired immunodeficiency syndrome

Abstract

Acute infections begin with an incubation period (IP) during which the virus genomes replicate and the host’s innate responses are initiated. The cytokines produced early in infection lead to classical symptoms of an acute infection: aches, pains, fever and malaise. Some viruses have short IF, as short as 1 day (influenza, rhinovirus), indicating that the symptoms are produced by local viral multiplication near the site of entry. There is little hope of treating most acute viral infections with antiviral drugs until rapid diagnostic tests become available. There are no antivirals for most common acute viral diseases. Acute viral infections are responsible for epidemics of disease involving millions of individuals each year such as influenza and measles. This chapter aims to cover a broad discussion on measles and rubella, influenza viruses, coronaviruses, respiratory syncytial virus, hepatotrophic viruses, cytomegalovirus epidemiology and transmission, herpes simplex viruses, varicella-zoster virus, Ebola, human immunodeficiency virus, etc.

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