This chapter will focus on the movement disorders in mainly various viral encephalitides and other infections also highlighting the diagnostic and prognostic significance of movement disorders associated with CNS infections. Various organisms such as viruses, bacteria, fungi, parasites, and spirochetes can affect the brain and result in the clinical syndrome of encephalitis. Encephalitis refers to the acute encephalitis syndrome which is characterized by of altered sensorium with fever. The clinical picture of encephalitis is nonspecific; however, the specific involvement of particular brain regions is responsible for the typical clinical presentations. Opsoclonus-myoclonus syndrome, chorea, dystonia, and Parkinsonism have also been described with malaria. Parkinsonism, tremor and rarely chorea, myoclonus, hemifacial spasm, and dystonia have been reported with neurocysticercosis.