Year Book of Dermatology – 2019 Acne

Savitha  AS; R Raghunatha Reddy; Shashi Kumar BM

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Year Book of Dermatology – 2019 Acne

by Savitha AS, R Raghunatha Reddy, Shashi Kumar BM

Acne is a skin disease which affects almost everybody at sometime during the lifetime. With more affluent concepts of living, this condition has become routinely seen in pre and post adolescent age group also. The Year Book of Dermatology – 2019 Acne has the advantage of compilation of all the recent advances in the field of Acne. This year book consists of 135 articles, which include treatment of moderate acne vulgaris in fitzpatrick skin type v or vi, novel tretinoin 0.05% lotion for the once-daily treatment of moderate-to-severe acne vulgaris, clinical experience with once-daily dapsone gel, 7.5% monotherapy in patients with acne vulgaris, analysis of gut microbiome in patients with acne vulgaris, acneiform eruptions, association of systemic antibiotic treatment of acne with skin microbiota characteristics, effects of the myrtle essential oil on the acne skin, vitamin D levels in acne vulgaris patients treated with oral isotretinoin, acne and nutrition: hypotheses, myths and facts, skin ecology during sebaceous drought, acne vulgaris in patients with hidradenitis suppurativa, etc. The Editors have not only compiled various research articles but also have given key messages and expert comments. This will help not only practitioners but also researchers and postgraduate residents.

Book Series: Year Book

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Book Detail

Editor	Editor's Affiliation
1. AS Savitha	Bangalore Medical College and Research Institute, Bengaluru, India
2. Reddy R Raghunatha	Dr Raghu’s Mathapitha Skin Clinic, Bengaluru, Karnataka, India
3. BM Shashi Kumar	Mandya Institute of Medical Sciences, Mandya, Karnataka, India
ISBN	9789389188493
Speciality	Dermatology
DOI	10.5005/jp/books/18287
Edition	1/e
Publishing Year	2019
Pages	234
Book Type	Professional

Chapters

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	Chapter Name	Pages	Action
	Prelims	i-xx
	Index	207-214
	Chapter-01 Treatment of Moderate Acne Vulgaris in Fitzpatrick Skin Type V or VI: Efficacy and Tolerability of Fixed Combination Clindamycin Phosphate 1.2%/Benzoyl Peroxide 3.75% Gel	1-1
	Chapter-02 Novel Tretinoin 0.05% Lotion for the Once-daily Treatment of Moderate-to-severe Acne Vulgaris: Assessment of Efficacy and Safety in Patients aged 9 Years and Older	2-2
	Chapter-03 Once-daily Oral Sarecycline 1.5 mg/kg/day is Effective for Moderate-to-severe Acne Vulgaris: Results from Two Identically Designed, Phase 3, Randomized, Double-blind Clinical Trials	3-3
	Chapter-04 The Efficacy and Safety of Azelaic Acid 15% Foam in the Treatment of Facial Acne Vulgaris	4-4
	Chapter-05 Frequency of Treatment Switching for Spironolactone Compared to Oral Tetracycline-class Antibiotics for Women with Acne: A Retrospective Cohort Study 2010–2016	5-6
	Chapter-06 Clinical Experience with Once-daily Dapsone Gel, 7.5% Monotherapy in Patients with Acne Vulgaris	7-7
	Chapter-07 An Acne Survey from the World's Largest Annual Gathering of Twins	8-8
	Chapter-08 Efficacy and Safety of Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel plus Oral Doxycycline in Subjects with Severe Inflammatory Acne who are Candidates for Oral Isotretinoin	9-9
	Chapter-09 Efficacy, Safety and Tolerability of Topical Dapsone Gel, 7.5% for Treatment of Acne Vulgaris by Fitzpatrick Skin Phototype	10-10
	Chapter-10 Clinical Significance of Neutrophil Gelatinase-associated Lipocalin and Galectin-7 in Tape-stripped Stratum Corneum of Acne Vulgaris	11-11
	Chapter-11 Risk of Depression among Patients with Acne: A Population-based Cohort Study using The Health Improvement Network (THIN) Database	12-12
	Chapter-12 Acne Development in Male Androgenetic Alopecia	13-13
	Chapter-13 Effects of Isotretinoin Treatment on Affective and Cognitive Functions in Adolescent Acne Vulgaris Patients	14-14
	Chapter-14 Analysis of Gut Microbiome in Patients with Acne Vulgaris	15-15
	Chapter-15 Isotretinoin Therapy: A Retrospective Cohort Analysis of Completion Rates and Factors Associated with Nonadherence	16-16
	Chapter-16 Photodynamic Therapy for Acne Conglobata of the Buttocks: Effective Anti-inflammatory Treatment with Good Cosmetic Outcome	17-17
	Chapter-17 Acneiform Eruptions: An Unusual Dermatological Side Effect of Ribavirin	18-18
	Chapter-18 Topical Dapsone Gel is a New Treatment Option for Acne Agminata	19-19
	Chapter-19 The Effect of Continuous High versus Low Dose Oral Isotretinoin Regimens on Dermcidin Expression in Patients with Moderate-to-severe Acne Vulgaris	20-20
	Chapter-20 Transgender Adolescents and Acne: A Case Series	21-21
	Chapter-21 Chemical Peels in the Treatment of Acne: Patient Selection and Perspectives	22-23
	Chapter-22 A Novel Cognitive Stress Management Technique for Acne Vulgaris: A Short Report of a Pilot Experimental Study	24-24
	Chapter-23 Evaluation of the Efficacy of Microneedle Fractional Radiofrequency in Turkish Patients with Atrophic Facial Acne Scars	25-26
	Chapter-24 Effect of Oral Isotretinoin on the Nucleocytoplasmic Distribution of FoxO1 and FoxO3 Proteins in Sebaceous Glands of Patients with Acne Vulgaris	27-28
	Chapter-25 Adult-onset Acne: Prevalence, Impact and Management Challenges	29-30
	Chapter-26 Acne: A Side Effect of Masculinizing Hormonal Therapy in Transgender Patients	31-31
	Chapter-27 Efficacy and Safety Profile of Spironolactone 50 mg v/s Isotretinoin 10 mg in the Treatment of Female Patients with Acne Vulgaris Grade 1-2—A Double Blinded, Randomized Comparative Study	32-33
	Chapter-28 The Microbiome in Preadolescent Acne: Assessment and Prospective Analysis of the Influence of Benzoyl Peroxide	34-34
	Chapter-29 Association of Systemic Antibiotic Treatment of Acne with Skin Microbiota Characteristics	35-35
	Chapter-30 Novel Nicotinamide Skin-adhesive Hot Melt Extrudates for Treatment of Acne	36-37
	Chapter-31 Treatment of Acne with a Combination of Propolis, Tea Tree Oil and Aloe vera Compared to Erythromycin Cream: Two Double-blind Investigations	38-38
	Chapter-32 The Safety and Efficacy of Four Different Fixed Combination Regimens of Adapalene 0.1%/Benzoyl Peroxide 2.5% Gel for the Treatment of Acne Vulgaris: Results from a Randomized Controlled Study	39-40
	Chapter-33 Survey of Acne-related Post-inflammatory Hyperpigmentation in the Middle East	41-41
	Chapter-34 The Use of Hormonal Antiandrogen Therapy in Female Patients with Acne: A 10-year Retrospective Study	42-42
	Chapter-35 Adapalene 0.3% Gel Shows Efficacy for the Treatment of Atrophic Acne Scars	43-44
	Chapter-36 Evaluation the Efficacy of Trichloroacetic Acid 33% in Treatment of Oral Retinoid-induced Cheilitis Compared with Placebo (Vaseline): A Randomized Pilot Study	45-45
	Chapter-37 Light Therapies for Acne: Abridged Cochrane Systematic Review including GRADE Assessments	46-47
	Chapter-38 Dapsone-loaded Invasomes as a Potential Treatment of Acne: Preparation, Characterization and In Vivo Skin Deposition Assay	48-48
	Chapter-39 Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-month Randomized, Vehicle-controlled Trial using Intra-individual Comparison	49-49
	Chapter-40 Complementary and Alternative Methods for Treatment of Acne Vulgaris: A Systematic Review	50-51
	Chapter-41 Effects of the Myrtle Essential Oil on the Acne Skin—Clinical Trials for Korean Women	52-52
	Chapter-42 Comparison of Efficacy of Commercially Available versus Freshly Prepared Salicylic Acid Peel in Treatment of Acne: A Randomized Open-label Study	53-53
	Chapter-43 A Comparison of Combined Oral Contraceptives Containing Chlormadinone Acetate versus Drospirenone for the Treatment of Acne and Dysmenorrhea: A Randomized Trial	54-55
	Chapter-44 Efficacy and Adverse Events of Oral Isotretinoin for Acne: A Systematic Review	56-57
	Chapter-45 Aromatherapy, Botanicals, and Essential Oils in Acne	58-58
	Chapter-46 A Review of Diagnosis and Treatment of Acne in Adult Female Patients	59-59
	Chapter-47 Clinical Evidence for Washing and Cleansers in Acne Vulgaris: A Systematic Review	60-61
	Chapter-48 ROS-responsive Microneedle Patch for Acne Vulgaris Treatment	62-62
	Chapter-49 Optimizing the Use of Topical Retinoids in Asian Acne Patients	63-63
	Chapter-50 Comparative Study of the Efficacy of Platelet-rich Plasma Combined with Carboxytherapy versus its Use with Fractional Carbon Dioxide Laser in Atrophic Acne Scars	64-65
	Chapter-51 Effects of Oral Supplementation with FOS and GOS Prebiotics in Women with Adult Acne: The “SO Sweet” Study: A Proof-of-concept Pilot Trial	66-66
	Chapter-52 Approaches to Limit Systemic Antibiotic Use in Acne: Systemic Alternatives, Emerging Topical Therapies, Dietary Modification, and Laser and Light-based Treatments	67-68
	Chapter-53 The Efficacy and Tolerability of 5-aminolevulinic Acid 5% Thermosetting Gel Photodynamic Therapy in the Treatment of Mild-to-moderate Acne Vulgaris. A Two-center, Prospective Assessor-blinded, Proof-of-concept Study	69-69
	Chapter-54 Combination Chemical Peels are More Effective than Single Chemical Peel in Treatment of Mild-to-moderate Acne Vulgaris: A Split Face Comparative Clinical Trial	70-71
	Chapter-55 Comparison of Efficacy of Aminolevulinic Acid Photodynamic Therapy versus Adapalene Gel plus Oral Doxycycline for Treatment of Moderate Acne Vulgaris – A Simple, Blind, Randomized, and Controlled Trial	72-72
	Chapter-56 Microneedling by Dermapen and Glycolic Acid Peel for the Treatment of Acne Scars: Comparative Study	73-74
	Chapter-57 Antipruritic Efficacies of Doxycycline and Erythromycin in the Treatment of Acne Vulgaris: A Randomized Single-blinded Pilot Study	75-75
	Chapter-58 Does Isotretinoin Cause Depression and Anxiety in Acne Patients?	76-77
	Chapter-59 Treatment of Atrophic Acne Scarring with Fractional Micro-plasma Radiofrequency in Chinese Patients: A Prospective Study	78-79
	Chapter-60 Comparison of Novel Dual Mode versus Conventional Single Pass of a 1450-nm Diode Laser in the Treatment of Acne Vulgaris for Korean Patients: A 20-week Prospective, Randomized, Split-face Study	80-81
	Chapter-61 Resurfacing of Facial Acne Scars with a New Variable-pulsed Er:YAG Laser in Fitzpatrick Skin Types IV and V	82-82
	Chapter-62 A Novel Topical Minocycline Foam for the Treatment of Moderate-to-severe Acne Vulgaris: Results of 2 Randomized, Double-blind, Phase 3 Studies	83-84
	Chapter-63 Management of Comedonal Acne Vulgaris with Fixed-combination Topical Therapy	85-85
	Chapter-64 Blunt Cannula Subcision is more Effective than Nokor Needle Subcision for Acne Scars Treatment	86-87
	Chapter-65 Novel Tretinoin 0.05% Lotion for the Once-daily Treatment of Moderate-to-severe Acne Vulgaris in a Preadolescent Population	88-89
	Chapter-66 Efficacy of Two Plant Extracts Against Acne Vulgaris: Initial Results of Microbiological Tests and Cell Culture Studies	90-90
	Chapter-67 Female Type of Adult Acne: Physiological and Psychological Considerations and Management	91-93
	Chapter-68 The Efficacy and Safety of Nonpharmacological Therapies for the Treatment of Acne Vulgaris: A Systematic Review and Best‐evidence Synthesis	94-95
	Chapter-69 Clindamycin Phosphate 1.2%/Benzoyl Peroxide 3% Fixed-dose Combination Gel versus Topical Combination Therapy of Adapalene 0.1% Gel and Clindamycin Phosphate 1.2% Gel in the Treatment of Acne Vulgaris in Japanese Patients: A Multicenter, Randomized, Investigator-blind, Parallel-group Study	96-96
	Chapter-70 Screening of Body Dysmorphic Disorder in Acne Patients: A Pilot Study	97-98
	Chapter-71 A Qualitative Investigation of the Impact of Acne on Health-related Quality of Life: Development of a Conceptual Model	99-99
	Chapter-72 Host-microbiome Interactions and Recent Progress into Understanding the Biology of Acne Vulgaris	100-101
	Chapter-73 Acne in Lomé, Togo: Clinical Aspects and Quality of Life of Patients	102-102
	Chapter-74 The Role of the Physician in Patient Perceptions of Barriers to Primary Adherence with Acne Medications	103-104
	Chapter-75 Exploring the Relationship between Stress and Acne: A Medical Student’s Perspective	105-105
	Chapter-76 The Impact of Acne and Facial Postinflammatory Hyperpigmentation on Quality of Life and Self-esteem of Newly Admitted Nigerian Undergraduates	106-106
	Chapter-77 Which Acne Treatment has the Best Influence on Health-related Quality of Life? Literature Review by the European Academy of Dermatology and Venereology Task Force on Quality of Life and Patient Oriented Outcomes	107-108
	Chapter-78 Stressful Life Events and Psychiatric Comorbidity in Acne–A Case Control Study	109-110
	Chapter-79 The Evaluation of Psychiatric Comorbidity, Self-injurious Behavior, Suicide Probability, and other Associated Psychiatric Factors (Loneliness, Self-esteem, Life Satisfaction) in Adolescents with Acne: A Clinical Pilot Study	111-111
	Chapter-80 Acne Relapses: Impact on Quality of Life and Productivity	112-112
	Chapter-81 The Mental Health Burden in Acne Vulgaris and Rosacea: An Analysis of the US National Inpatient Sample	113-114
	Chapter-82 The Therapeutic Effect of Tanshinone IIA on Propionibacterium acnes-induced Inflammation In Vitro	115-115
	Chapter-83 Anti-acne Properties of Hydrophobic Fraction of Red Ginseng (Panax Ginseng C.A. Meyer) and its Active Components	116-117
	Chapter-84 Mechanistic Insight into the Activity of a Sulfone Compound Dapsone on Propionibacterium (Newly Reclassified as Cutibacterium) Acnes–mediated Cytokine Production	118-119
	Chapter-85 Lipidomics Reveals Skin Surface Lipid Abnormity in Male Youth Acne	120-120
	Chapter-86 Acne Vulgaris Severity Graded by In Vivo Reflectance Confocal Microscopy and Optical Coherence Tomography	121-123
	Chapter-87 Vitamin D Levels in Acne Vulgaris Patients Treated with Oral Isotretinoin	124-124
	Chapter-88 The Effect of Milk Consumption on Acne: A Meta-analysis of Observational Studies	125-126
	Chapter-89 Acne and Nutrition: Hypotheses, Myths and Facts	127-128
	Chapter-90 Enhancement of Lipid Content and Inflammatory Cytokine Secretion in SZ95 Sebocytes by Palmitic Acid Suggests a Potential Link between Free Fatty Acids and Acne Aggravation	129-129
	Chapter-91 Characterization of Cutibacterium acnes Phylotypes in Acne and In Vivo Exploratory Evaluation of Myrtacine	130-131
	Chapter-92 Atrophic Scar Formation in Acne Patients involves Long-acting Immune Responses with Plasma Cells and Alteration of Sebaceous Gland	132-133
	Chapter-93 Lesional and Circulating Levels of Interleukin‐17 and 25 Hydroxy-cholecalciferol in Active Acne Vulgaris: Correlation to Disease Severity	134-135
	Chapter-94 Clinical Efficacy of 0.5% Topical Mangosteen Extract in Nanoparticle Loaded Gel in Treatment of Mild‐to‐moderate Acne Vulgaris: A 12‐Week, Split‐Face, Double‐blinded, Randomized, Controlled Trial	136-137
	Chapter-95 The Influence of Exposome on Acne	138-138
	Chapter-96 Association of Interleukin-6 Gene Promoter Polymorphism with Acne Vulgaris and its Severity	139-140
	Chapter-97 Genome-wide Meta-analysis Implicates Mediators of Hair Follicle Development and Morphogenesis in Risk for Severe Acne	141-142
	Chapter-98 Microbiological Profile of Sarecycline: A Novel Targeted Spectrum Tetracycline for the Treatment of Acne Vulgaris	143-143
	Chapter-99 Daily Intake of Soft Drinks and Moderate-to-severe Acne Vulgaris in Chinese Adolescents	144-145
	Chapter-100 New Concepts, Concerns, and Creations in Acne	146-147
	Chapter-101 The Anti-inflammatory Activities of Propionibacterium acnes CAMP Factor-targeted Acne Vaccines	148-148
	Chapter-102 Skin Ecology during Sebaceous Drought—How Skin Microbes Respond to Isotretinoin	149-149
	Chapter-103 Propionibacterium acnes-derived Extracellular Vesicles Promote Acne-like Phenotypes in Human Epidermis	150-151
	Chapter-104 Patients with Acne Vulgaris have a Distinct Gut Microbiota in Comparison with Healthy Controls	152-152
	Chapter-105 Inhibitory Effects of Euphorbia supina on Propionibacterium acnes-induced Skin Inflammation In Vitro and In Vivo	153-153
	Chapter-106 Isolation and Identification of the Follicular Microbiome: Implications for Acne Research	154-155
	Chapter-107 Expression of Inflammatory and Fibrogenetic Markers in Acne Hypertrophic Scar Formation: Focusing on Role of TGF-β and IGF-1R	156-157
	Chapter-108 Decrease in Diversity of Propionibacterium acnes Phylotypes in Patients with Severe Acne on the Back	158-158
	Chapter-109 Short Lipopeptides Specifically Inhibit the Growth of Propionibacterium acnes with Antibacterial and Anti-inflammatory Dual Action	159-160
	Chapter-110 Plasma Exeresis for Active Acne Vulgaris: Clinical and In Vivo Microscopic Documentation of Treatment Efficacy by Means of Reflectance Confocal Microscopy	161-161
	Chapter-111 Licochalcone A Attenuates Acne Symptoms Mediated by Suppression of NLRP3 Inflammasome	162-162
	Chapter-112 Gut Microbiota Alterations in Moderate-to-severe Acne Vulgaris Patients	163-163
	Chapter-113 Overall and Subgroup Prevalence of Acne Vulgaris among Patients with Hidradenitis Suppurativa	164-165
	Chapter-114 Association of the TNF-α Gene Promoter Polymorphisms at Nucleotide-238 and -308 with Acne Susceptibility: A Meta-analysis	166-166
	Chapter-115 Tumor Necrosis Factor a-308 G/A and Interleukin 1 b-511 C/T Gene Polymorphisms in Patients with Scarring Acne	167-168
	Chapter-116 SIG1459: A Novel Phytyl-Cysteine Derived TLR2 Modulator with In Vitro and Clinical Anti-acne Activity	169-169
	Chapter-117 Associations among Two Vitamin D Receptor (VDR) Gene Polymorphisms (ApaI and TaqI) in Acne Vulgaris: A Pilot Susceptibility Study	170-171
	Chapter-118 Using Network Oriented Research Assistant (NORA) Technology to Compare Digital Photographic with In-Person Assessment of Acne Vulgaris	172-172
	Chapter-119 Genetic Association between the NLRP3 Gene and Acne Vulgaris in a Chinese Population	173-174
	Chapter-120 Serum Irisin: A Prognostic Marker for Severe Acne Vulgaris	175-177
	Chapter-121 Primary Sebocytes and Sebaceous Gland Cell Lines for Studying Sebaceous Lipogenesis and Sebaceous Gland Diseases	178-179
	Chapter-122 Acne Vulgaris in Patients with Hidradenitis Suppurativa	180-180
	Chapter-123 Validation of 3D Skin Imaging for Objective Repeatable Quantification of Severity of Atrophic Acne Scarring	181-182
	Chapter-124 No Evidence for Follicular Keratinocyte Hyperproliferation in Acne Lesions as Compared to Autologous Healthy Hair Follicles	183-184
	Chapter-125 Seasonal Changes in Epidermal Ceramides are Linked to Impaired Barrier Function in Acne Patients	185-186
	Chapter-126 Cutibacterium acnes (Propionibacterium acnes) and Acne Vulgaris: A Brief Look at the Latest Updates	187-188
	Chapter-127 The In Vitro Antimicrobial Evaluation of Commercial Essential Oils and their Combinations against Acne	189-191
	Chapter-128 Seasonal Aggravation of Acne in Summers and the Effect of Temperature and Humidity in a Study in a Tropical Setting	192-193
	Chapter-129 Acne Prevalence in 9–14‐year‐old Patients Attending Pediatric Ambulatory Clinics in Italy	194-195
	Chapter-130 Confocal Microscopy in Adult Women with Acne	196-197
	Chapter-131 Erythema‐directed Digital Photography for the Enhanced Evaluation of Topical Treatments for Acne Vulgaris	198-199
	Chapter-132 Acne Vulgaris: The Metabolic Syndrome of the Pilosebaceous Follicle	200-201
	Chapter-133 Circular RNA Expression Profile Analysis of Severe Acne by RNA‐Seq and Bioinformatics	202-203
	Chapter-134 Taxonomy and Phylogeny of Cutibacterium (formerly Propionibacterium) acnes in Inflammatory Skin Diseases	204-204
	Chapter-135 Transforming Acne Care by Pediatricians: An Interventional Cohort Study	205-206