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by Daniel H. Scorsetti, Victor L. Perez, Jose Alvaro Pereira Gomes
The book, Stem Cells in Ophthalmology, is a testimony of stem cell therapy in ophthalmology which has evolved from general ideas to structured concepts. This amplification of the stem cell field in ophthalmology has also seen the realization of extraordinary new discoveries in other fields. As the field of stem cell biology and therapy is rapidly evolving, this book captures in present time where in ophthalmology we stand with respect to the use of stem cell therapy to regenerate all the structures of the visual system and ocular adnexa. This book reviews basic stem cell biology and immunity and covers unique advances or present state-of-the-art use of these cells in ocular tissue. The final chapter covers the description of the facilities and governmental requirements needed to establish an ocular stem cell program.
1. Scorsetti Daniel H.
||School of Medicine, USAL; CEOS, Buenos Aires, Argentina|
2. Perez Victor L.
||Ocular Surface Center; University of Miami Miller School of Medicine, Bascom Palmer Eye Institute, Miami, FL (USA)|
|3. Gomes Jose Alvaro Pereira||Universidade Federal de S. Paulo – UNIFESP/EPM; Anterior Segment Area and Advanced Ocular Surface Center (CASO) UNFESP/EPM; Sociedad Panamericana de Cornea (PanCornea), Sao Paulo, Brazil|
|Chapter-01 Stem Cells||1-14|
|Chapter-02 Ocular Surface Epithelia Side Population Stem Cells: Isolation, Molecular Signatures and Approaches to Activation and Self Renewal for Tissue Regeneration||15-36|
|Chapter-03 Cultivation In Vitroand Ex Vivo||37-50|
|Chapter-04 Avoiding Rejection: Immunological Aspectsfor Successful Stem Cell Therapy||51-60|
|Chapter-05 Ocular SurfaceStem Cells: Science and Surgery||61-80|
|Chapter-06 Corneal Stromal Keratocytes and Endothelial Cells||81-92|
|Chapter-07 Restricted Pluripotent Cells and Their Integration into the Trabecular Meshwork||93-100|
|Chapter-08 Crystalline Lens Stem Cells, Reparation and Regeneration||101-108|
|Chapter-09 Stem Cells in the Orbit andOcular Adnexal Tissue||109-124|
|Chapter-10 Cell Therapy for Total Limbal Stem Cell Deficiency||125-134|
|Chapter-11 Cell Therapy for Corneal Endothelial Dysfunction||135-148|
|Chapter-12 Cell Therapy for Retinal, Optic Nerve andVisual Tract Diseases||149-164|
|Chapter-13 Role of Stem Cells in Lacrimal and Meibomian Gland Development and Regeneration||165-178|
|Chapter-14 Towards the Use of Non-Ocular Cell Lineages in Ocular Surface Disease||179-186|
|Chapter-15 Induced PluripotentStem Cells and TheirPotential to TreatEye Diseases||187-194|
|Chapter-16 Gene Therapy||195-216|
|Chapter-17 Protocols, Facilities, Equipment, Materials and Regulations for Establishing a Human Stem Cell Program||217-226|
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