Objective: This study is designed to compare the symptomatic profile of chronic rhinosinusitis (CRS) before and after functional endoscopic sinus surgery (FESS) by 20-item Sino-Nasal Outcome Test (SNOT-20) questionnaire. Study design: Open prospective observational study. Materials and methods: A group of 40 patients with symptoms of CRS were included in the study. They underwent FESS at the Department of ENT, Command Hospital, Air Force, Bengaluru, from July 2014 to December 2015. Patients were assessed for CRS symptoms preoperatively and postoperatively by SNOT-20 questionnaire. Follow-up of patients was done at 1 week, 2 weeks, 1 month, 3 months, and 6 months respectively, by SNOT-20 score. Results: There was a significant difference noted in overall SNOT-20 score as well as improvement in symptoms at the end of 6 months. Conclusion: A good objective outcome in terms of symptoms improvement can be obtained with FESS in patients with CRS by SNOT-20.