The current coronavirus-19 (COVID-19) pandemic has diverted the world's attention to the burning problem of infectious diseases and their management. Clinicians are increasingly realizing that the management of diseases like COVID-19 requires not only antimicrobial drugs but also drugs or strategies to tackle the various comorbidities occurring or aggravating due to the disease. Hypoglycemia is one of the important adverse effects of hydroxychloroquine, used frequently in COVID-19. The known diabetics affected with COVID-19 are therefore at a greater risk of hypoglycemia. In this review article, we describe the management strategy for the known diabetics infected with COVID-19 and admitted in inpatient settings, including the dose calculations for insulin infusion and subcutaneous administration of insulin.