Red Cell Distribution Width as a Novel Prognostic Marker in Multiple Clinical Studies

JOURNAL TITLE: Indian Journal of Critical Care Medicine

Author
1. Bahman Yousefi
2. Hassan Soleimanpour
3. Ali A Ghamari
4. Ansar Karimian
ISSN
0972-5229
DOI
10.5005/jp-journals-10071-23328
Volume
24
Issue
1
Publishing Year
2020
Pages
6
Author Affiliations
    1. Department of Clinical Biochemistry, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Islamic Republic of Iran
    1. Department of Anesthesiology, Tabriz University of Medical Sciences, Tabriz, Islamic Republic of Iran
    1. Department of Anesthesiology, Tabriz University of Medical Sciences, Tabriz, Islamic Republic of Iran
    1. Department of Clinical Biochemistry, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Islamic Republic of Iran
  • Article keywords
    Hemoglobin, Prognosis, Red cell distribution width

    Abstract

    Red cell distribution width (RDW), which is a quantitative method applied for the measurement of anisocytosis, is the most reliable and inexpensive method for differentiation of iron deficiency anemia and thalassemia trait. An increase in its rate reflects a great heterogeneity in the size of red blood cells (RBCs). Recent studies have shown a significant relationship between RDW and the risk of morbidity and mortality in patients with multiple diseases. A strong association is established between changes in RDW and the risk of adverse outcome in patients with heart failure in multiple studies. In this review, we try to focus on the association and correlation between the increase in RDW and different outcomes of common diseases that may be related to RDW and based on the results of various studies, we are trying to introduce RDW as a diagnostic indicator for these diseases.

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