Clinical and Radiographic Evaluation of 3Mix and Vitapex as Pulpectomy Medicament in Primary Molars: An In Vivo Study

JOURNAL TITLE: International Journal of Clinical Pediatric Dentistry

1. Pradeep M Chandrappa
2. Ramya Rai
3. Zeenath Ambareen
4. Prashant Babaji
5. Vundela R Reddy
6. Kukkalli K Shashibhushan
Publishing Year
Author Affiliations
1. com.mps.common.model.Contributor@b45cfae ,
2. com.mps.common.model.Contributor@50fb3af6 ,
3. com.mps.common.model.Contributor@7ef77638 ,
4. com.mps.common.model.Contributor@454fa50a ,
5. com.mps.common.model.Contributor@60d23ab2 ,
6. com.mps.common.model.Contributor@697790d4
Article keywords
3Mix, Lesion sterilization and tissue repair care, Nonvital pulp treatment, Primary teeth, Vitapex


Objective: To evaluate the clinical and radiographic success rates of 3Mix and Vitapex in the treatment of necrosed primary teeth. Materials and methods: Seventy teeth of healthy children aged 4–9 years with necrotic primary molar (nonvital) were treated with 3Mix (lesion sterilization tissue repair therapy) and Vitapex before restoration with stainless steel crowns. The participants were followed up clinically and radiographically for 3 months and 6 months, respectively. The outcome was compared using Fisher exact test with a significance level of p < 0.05. Results: Clinical success rate of 3Mix group at 3 months and 6 month follow-up was 100% and 97.14% and that of Vitapex group was 100% and 100%, respectively. The radiographic success rate of 3Mix group at 3 months and 6 months was 74.29% and 77.14% and of Vitapex group was 97.14% and 97.14%, respectively. Considering the clinical success, no statistical difference was found between the two groups at the end of 6 month (p = 1.000). But radiographically statistical significant difference was found between the two groups (p = 0.028). Conclusion: Non-instrumentation endodontic treatment using 3Mix has shown a good clinical success of 97.14% but the radiographic success rate at 6 months was lower (77.14%). So it can be suggested that the use of 3Mix antibiotic treatment cannot replace conventional root canal treatment over the long term.

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