Variations in Physiological, Psychomotor, and Analgesic Parameters during Titration of Nitrous Oxide in 3–12 Years Old Children Managed with Inhalation Sedation

JOURNAL TITLE: International Journal of Clinical Pediatric Dentistry

Author
1. Kunal Gupta
2. Vinod Sachdev
3. Radhika Chopra
4. Shivangi Sharma
ISSN
0974-7052
DOI
10.5005/jp-journals-10005-1852
Volume
13
Issue
6
Publishing Year
2020
Pages
6
Author Affiliations
    1. Department of Pedodontics and Preventive Dentistry, ITS Centre for Dental Studies and Research, Muradnagar, Uttar Pradesh, India
    1. Department of Pedodontics, ITS Centre for Dental Studies and Research, Ghaziabad, Uttar Pradesh, India
    1. Department of Pedodontics, Himachal Dental College, Sundar Nager, Himachal Pradesh, India
    1. Department of Oral and Maxillofacial Surgery, Modern Dental College and Research Centre, Indore, Madhya Pradesh, India
  • Article keywords

    Abstract

    Background: The present study was designed to assess variations in physiological, psychomotor parameters, and analgesic effects at various levels of nitrous oxide-oxygen analgesia in 3–12 years old children. Design: One hundred children aged 3–12 years were assessed for physiological, psychomotor, and analgesic parameters at various concentrations of N2O, i.e., baseline, 20, 40, 50, and 0% (100% O2). Physiological, psychomotor, and analgesic effects were assessed using a pulse oximeter, bender visual-motor Gestalt test, and response to electric pulp tester, respectively. Results: Oxygen saturation (SpO2) showed a significant increase while heart rate (HR) showed a significant reduction at 50% N2O. No significant changes were observed in respiratory rate with a change in N2O levels. Significant reduction in the pain scores was found at the same level of stimulation by an electric pulp tester at 40 and 50% levels. The psychomotor changes were consistently higher at every concentration of nitrous oxide. However, no correlation could be found between various parameters tested. Conclusion: N2O caused a significant increase in SpO2 in both the age groups, a decrease in HR, a significant decrease in pain score at 40 and 50% concentration of N2O, and had a significant effect on the psychomotor ability of children.

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