Giant Cell Epulis as a Presenting Manifestation of Primary Hyperparathyroidism: A Case Series from a Tertiary Care Center

JOURNAL TITLE: Indian Journal of Endocrine Surgery and Research

Author
1. Akanksha Gautam
2. Sanjay K Bhadada
3. Divya Dahiya
4. Kishore Abuji
5. Manoj K Thumma
ISSN
DOI
10.5005/jp-journals-10088-11228
Volume
19
Issue
1
Publishing Year
2024
Pages
4
Author Affiliations
    1. Department of General Surgery, ESIC Medical College, Hyderabad, India
    1. Department of Endocrinology, PGIMER, Chandigarh, India
    1. Department of Surgery, PGIMER, Chandigarh, India
    1. Department of Surgery, PGIMER, Chandigarh, India
  • Article keywords
    Case report, Epulis, Giant cell granuloma, Hyperparathyroidism, Primary hyperparathyroidism

    Abstract

    Brown tumors are sequelae of abnormal bone metabolism in primary hyperparathyroidism (PHPT) when there is increase in osteoclastic activity and fibroblastic proliferation. They can be located in any part of the skeleton, but commonly affect the bony thorax (ribs and clavicle), pelvic rim, and long bones (tibia and femur). Clinically, significant lesions in the craniofacial bones are rare and usually involve the mandible. Oral manifestation may be the only presenting feature of PHPT and patient generally report first to a maxillofacial surgeon with a diagnosis of a giant cell tumor which is very similar in clinical, radiological, and histological features to brown tumor. Therefore, we aim to share our experience of giant cell epulis as a presenting manifestation in PHPT patients in a tertiary care center in North India.

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