Oral lesions of tuberculosis, though uncommon, are often seen in both the primary and secondary stages of the disease. In secondary tuberculosis, the oral manifestations may be accompanied by lesions in the lungs, lymph nodes, or in any other part of the body and can be detected by a systemic examination. Primary oral tuberculosis may present as a diagnostic challenge for the clinician. Here we report a case of tuberculosis of oral cavity with primary in lung (a cavity lesion) and sputum positive for acid fast bacilli. However, the biopsy from the lesion was negative.