Insight into the pathophysiology of insomnia

JOURNAL TITLE: Indian Journal of Sleep Medicine

Author
1. Deepak Shrivastava
ISSN
0973-340X
DOI
10.5958/0974-0155.2014.01099.7
Volume
9
Issue
1
Publishing Year
2014
Pages
4
Author Affiliations
    1. Medical Director, SJGH Sleep Center, French Camp, CA; Clinical Professor UC Davis School of Medicine; Faculty, ACGME Accredited Sleep Medicine Fellowship Program, UCDMC, Sacramento, CA USA
  • Article keywords

    Abstract

    Insomnia is a major public health hazard. Complexity of insomnia patho-physiology is intriguing and is an exciting subject of inquiry. The current article summarizes the recent developments in our understanding of insomnia. Although the early models of insomnia were unidirectional, they provided foundation for development of more integrative models. Sleep- wake regulation and more specifically conceptual understanding of sleep homeostasis, circadian influence, and hyperarousal further added new dimensions to our understanding of insomnia. However, there is more appreciation than ever of the fact that a lot more work must be done before even thinking about finding a conclusive evidence of what causes insomnia and what maintains it. Some of the legendary work is cited in the reference section to develop an understanding of intricate interplay of multiple systems within the body that cause sleep and lack of it.

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