A Study to Evaluate Sleep-disordered Breathing in Patients with Chronic Respiratory Failure

JOURNAL TITLE: Indian Journal of Sleep Medicine

Author
1. Pankaj Gupta
2. Debasis Behera
3. B Viswesvaran
ISSN
0973-340X
DOI
10.5005/jp-journals-10069-0050
Volume
15
Issue
1
Publishing Year
2020
Pages
4
Author Affiliations
    1. Department of Pulmonary, Critical Care and Sleep Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India
    1. Department of Pulmonary, Critical Care and Sleep Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India
  • Article keywords
    Chronic respiratory failure, Comorbidity, Sleep-disordered breathing, Undiagnosed

    Abstract

    Introduction: Sleep-disordered breathing (SDB) in patients with chronic respiratory failure (CRF) due to pulmonary disease remains an underrated and undiagnosed entity. Materials and methods: A prospective descriptive study in patients with CRF with history suggestive of SDB was carried out using polysomnography (PSG) over a period of 12 months. Results: Thirty patients with the Epworth sleepiness scale greater than 11 and CRF underwent PSG. Ninety percent patients had obstructive sleep apnea (OSA) syndrome using the respiratory disturbance index (RDI) of 5 as cut-off. Mean RDI was 13.4 and mean apnea-hypopnea Index (AHI) was 10.5. Besides, the patients had a poor sleep quality; sleep efficiency was 69.38 ± 14.44%, sleep onset time was 30.35 ± 24.31 minutes. Wake after sleep onset (WASO) was 107.25 ± 57.71 minutes. Rapid-eye-movement (REM) sleep latency was 126.08 ± 66.61 minutes. N1 was 23.75 ± 14.89, N2 was 45.22 ± 12.69, N3 was 20.02 ± 12.57, and REM sleep period was 11.33 ± 8 minutes. The body mass index (BMI) and Epworth sleepiness score (ESS) had a significant correlation with AHI with p value < 0.005. Conclusion: Sleep-disordered breathing is an important comorbidity in patients with CRF leading to increased morbidity and mortality. A high of suspicion must be kept for the same especially in patients with higher BMI and high ESS. Such patients have a poor quality of sleep besides increased incidence of sleep apnea.

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