Clinical Trial of an Experimental Cleaning Solution: Antibiofilm Effect and Integrity of a Silicone-based Denture Liner

JOURNAL TITLE: The Journal of Contemporary Dental Practice

Author
1. Antonio de Luna Malheiros Segundo
2. Marina Xavier Pisani
3. Cássio do Nascimento
4. Raphael Freitas Souza
5. Helena de Freitas Oliveira Paranhos
6. Cláudia Helena Silva-Lovato
ISSN
DOI
10.5005/jp-journals-10024-1575
Volume
15
Issue
5
Publishing Year
2014
Pages
9
Author Affiliations
    1. Department of Dental Materials and Prosthodontics, Ribeirao Preto Dental School, University of São Paulo, Ribeirao Preto São Paulo, Brazil
    1. Department of Dental Materials and Prosthodontics, Ribeirao Preto Dental School, University of São Paulo, Ribeirao Preto São Paulo, Brazil
    1. Department of Dental Materials and Prosthodontics, Ribeirao Preto Dental School, University of São Paulo, Ribeirao Preto São Paulo, Brazil
    1. Department of Dental Materials and Prosthodontics, Ribeirao Preto Dental School, University of São Paulo, Ribeirao Preto São Paulo, Brazil
    1. Department of Dental Materials and Prosthodontics, Ribeirao Preto Dental School, University of São Paulo, Ribeirao Preto São Paulo, Brazil
    1. Department of Dental Materials and Prosthodontics, Ribeirao Preto Dental School, University of São Paulo, Ribeirao Preto São Paulo, Brazil
  • Article keywords

    Abstract

    Aim

    This study evaluated the antibiofilm effect of an experimental solution of 2% Ricinus communis (R. communis) on a silicone-based denture liner by means of a randomized clinical trial, as well as the integrity of such liner following a cleansing regimen with such solution.

    Materials and methods

    About 30 complete denture wearers had their lower dentures relined with a silicone-based denture liner and randomly allocated to cleanse their dentures by means of: (A) a specific toothbrush for complete dentures and dentifrice; (B) soaking in an experimental 2% R. communis solution; and (C) association of A and B. Considered outcomes were biofilm coverage area (%), microbial counts by means of the deoxyribonucleic acid (DNA) checkerboard hybridization technique and physical integrity of the soft liner, assessed during a time interval of 60 days. Mean group values were compared by analysis of variance (ANOVA) and Tukey tests or generalized linear method (α = 0.05).

    Results

    The mechanical method presented the lowest biofilm percentage (1.45 ± 1.03) if compared to the chemical method (2.96 ± 1.98) and the associated one (2.71 ± 1.76). After 60 days (3.37 ± 2.04), biofilm accumulation was higher than at 15 days (1.28 ± 0.77) and 30 days (2.46 ± 1.54). The denture liner was less deteriorated and kept its physical integrity when the mechanical method was applied. The chemical method presented higher effectiveness against microorganisms, including some Candida species.

    Conclusion

    The 2% R. communis solution presented stronger antimicrobial capacity than brushing on a silicone-based denture liner after immersion. However, it was not superior to the mechanical method in preserving the physical integrity of the material and in biofilm removal.

    Clinical significance

    Soft denture liners hygiene is a very important issue and not conclusive in the literature. The experimental solution of 2% R. communis evaluated presented promising antimicrobial potential and should be more explored to be recommended as cleanser.

    How to cite this article

    de Luna Malheiros Segundo A, Pisani MX, do Nascimento C, Souza RF, de Freitas Oliveira Paranhos H, Silva-Lovato CH. Clinical Trial of an Experimental Cleaning Solution: Antibiofilm Effect and Integrity of a Silicone-based Denture Liner. J Contemp Dent Pract 2014;15(5):534-542.

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