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JOURNAL TITLE: The Journal of Medical Sciences
Introduction: Cystadenofibroma of the ovary is a rare benign epithelial tumor of the ovary that impersonates with malignant features like solid nodule and papillae on imaging as well on gross examination of the specimen. Case description: A 20-year-old unmarried girl visited our outpatient department with a complaint of pain in the lower abdomen for the last 1 year. Transabdominal ultrasonography revealed a well-defined complex cyst of about 9.4 × 7.4 cm size with a small echogenic nodule of 1.74 × 0.8 cm involving the left ovary. On color Doppler, there was an absence of increased internal vascularity. The right ovary was normal. CA 125 was within normal limits. She underwent laparoscopy, multiple solid papillae were seen after removal of a cyst, left salpingo-oophorectomy was done due to suspicion of malignancy. However, the final histopathology report revealed benign cystadenofibroma of the ovary. Conclusion: Although there are no confirmatory imaging diagnostic tests to differentiate benign cystadenofibroma from malignant pathology, however, absent blood flow is significantly associated with the benign nature of ovarian cystadenofibromas despite solid nodule and papillae within it. An intraoperative frozen section may help in diagnosis and prevent extensive surgery in patients.
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