Brucellosis: A Case Report and Literature Review

JOURNAL TITLE: Journal of Postgraduate Medicine, Education and Research

Author
1. Sana Saeed
2. Mahnaz Hakeem
ISSN
2277-8969
DOI
10.5005/jp-journals-10028-1328
Volume
53
Issue
3
Publishing Year
2019
Pages
2
Author Affiliations
    1. Department of Paediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan
    1. Department of Paediatrics and Child Health, Aga Khan University Hospital, Karachi, Pakistan
  • Article keywords
    Brucellosis, Pyrexia of unknown origin, Zoonotic disease

    Abstract

    Brucellosis is a major cause of febrile illnesses in areas with high exposure to animals or unpasteurized milk and dairy products. It may manifest with multisystem clinical presentations. Our patient was a six-year-old boy who was presented in emergency room with a prolonged history (3 weeks) of high-grade fever with chills, not responding to antibiotics. Upon inquiry, the history revealed the use of unpasteurized goat milk and contact with goats at home. Upon investigation, serum antibodies for brucellosis were raised (1:640). He was started on combination therapy with rifampicin and doxycycline. He became afebrile within two days so was discharged home. We found that an ineffective history could lead to delay in diagnosis and management. Clinicians should have high index of suspicion for brucellosis in children.

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