The disseminated staphylococcal disease can lead to massive pyopericardium, cardiac tamponade, and myocardial dysfunction. The management includes prompt initiation of intravenous antibiotics, assessment by echocardiography, and/or computed tomography of the chest, urgent drainage by pericardial catheter, and inotropic support. The surgical intervention may be needed in cases with nonimprovement in clinical status.
