Clinical Evaluation of Brahmi Ghrita and Jyotishmati Taila in the Management of Cognitive Deficit in Children

JOURNAL TITLE: Journal of Research in Ayurvedic Sciences

1. D Sudhakar
2. Pradeep K Dua
3. Gurucharan Bhuyan
Publishing Year
Author Affiliations
    1. Advanced Centre for Ayurveda, Association for Child and Adolescent Mental Health, Bengaluru, Karnataka, India
    1. Central Council for Research in Ayurvedic Sciences, New Delhi, India
  • Article keywords
    Brahmi ghrita, Buddhimandyata, Cognitive deficit, Jyotishmati taila


    Introduction: Cognition refers to the perceptual and intellectual aspects of mental functioning. A deficit in intellectual performances results in lack of cognition process to cognition deficit. The present study is carried out to evaluate the efficacy of Brahmi gritha and Jyotishmathi taila in cognitive deficit. Materials and Methods: Brahmi ghrita has given orally in a dose of 10 gms twice daily with warm water/milk before food and Jyotishmati taila given as Pratimarsha Nasya (2-2 drops) in each nostril twice daily for a period of 12 weeks to evaluate the effect on clinical symptoms of Cognitive deficit and changes in mini-mental state examination (MMSE). Seventy-six cognitive deficit children were selected from outpatient department (OPD) of this Institute. Observations and Results: Clinical symptoms revealed encouraging results such as lack of curiosity 100 to 11.9%, poor attention from 95.55 to 13.4%, moderate responses in decreased learning ability from 100 to 59.7%, mild response in the symptoms like language skill from 65.7 to 59.7%, asking same questions repeatedly from 20.9 to 17.9% and inability to understand and follow the directions from 89.6 to 86.6%. No response was observed in the symptoms like meeting educational demands in school and getting lost in the neighborhood and inability to get home. It provided significant effect on all symptoms of MMSE except registration and sensory perception at the end of the 84th day of the study. At the follow-up study (at the end of 14th week) it provided an insignificant effect on attention and concentration and registration and sensory perception. Lab reports show that no significant changes occur in almost all hematological parameters. Conclusion: It may be interpreted that these medicines are safe for administration and also effective to improve the clinical symptoms of the cognitive deficit children.

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