Aim: To investigate the efficacy of chromohysteroscopy in evaluation of endometrial pathologies in patients with abnormal uterine bleeding (AUB).
Materials and methods: Fifty patients with AUB without any macroscopic abnormalities of endometrium on hysteroscopy were included in the study. After instillation of methylene blue dye, chromohysteroscopy was performed. The pattern of endometrial staining was noted. Biopsies were taken from stained and unstained areas and sent for histopathological examination.
Results: Of the 50 patients included in the study, 36 had diffuse staining and 14 had focal staining pattern of endometrium. Of the 13 cases with endometrial pathologies on histopathology, 10 had focal staining pattern. The diagnostic accuracy of the stained endometrium in cases with focal staining, for detection of endometrial pathologies was statistically significant when compared to the unstained areas with a sensitivity of 76%, specificity 89%, positive predictive value 71% and negative predictive value of 92%.
Conclusion: Chromohysteroscopy helps improve the diagnostic accuracy of conventional hysteroscopy.
Clinical significance: Chromohysteroscopy can be used as an adjunct to identify the target areas to be biopsied in cases with macroscopically normal appearing endometrium on hysteroscopy.