Pertussis in infants can be a severe disease leading to higher morbidity and mortality. Infants are usually protected from the disease by virtue of maternal antipertussis antibodies. Those infants where these protective antibodies are lacking due to nontransfer or low maternal antipertussis antibody are at higher risk of the disease. Herein, we report a series of four infants diagnosed with pertussis, bringing to light the fact that infant pertussis is not so uncommon in India and probably due consideration should be given for universalization of antenatal pertussis vaccine.