Introduction: Tobacco consumption is perhaps the single largest cause of death. Around 20-25 years of them lost their productive life, leading to an irreparable loss of economic and human resource.¹ Objectives: To assess the knowledge, attitude and practice of women regarding hazards of tobacco consumption, to identify the health problem Methods: A descriptive design was used in this study. 60 women from urban and 60 women from rural was selected by using simple random method (Lottery method). Totally 120 women were selected for the study. Data were collected by using semi-structured interview questionnaire which consisted of questions related to Knowledge, Attitude, Practice Result: revealed that, in urban area 35% of the subjects were having average knowledge and 65% were having better knowledge on hazards of tobacco consumption. But in rural area the data showed that 25% were having average knowledge on hazards of tobacco consumption. Attitude and practice of tobacco consumption in rural and urban areas shows that in rural area 78.3% of the subjects were having uncertain attitude and 21.7% were having agreeing attitude where as in urban area the data shows that 68.3% of the subjects were having uncertain attitude and 31.7% were having agreeing attitude. As a result the investigator found that the rural women were having uncertain attitude when compared to urban area. Conclusion: The findings of this study showed that nurses has the responsibility in teaching and motivating regarding hazards of tobacco consumption among women in rural and urban area to prevent oral cancer.