A Synchronous Metastatic Growth in Thyroid Gland from Carcinoma Cervix

JOURNAL TITLE: World Journal of Endocrine Surgery

Author
1. Pooja Ramakant
2. Suresh Babu
3. Chanchal Rana
4. Preeti Khokhar
5. Kulranjan Singh
ISSN
0975-5039
DOI
10.5005/jp-journals-10002-1266
Volume
11
Issue
3
Publishing Year
2019
Pages
4
Author Affiliations
    1. Department of Pathology, King George\'s Medical University, Lucknow, Uttar Pradesh, India
    1. Department of Endocrine Surgery King Georges’ Medical University Lucknow, Uttar Pradesh, India
    2. King George’s Medical University, Lucknow, Uttar Pradesh, India
    1. Department of Endocrine Surgery, King George\'s Medical University, Lucknow, Uttar Pradesh, India
    1. Department of Pathology, King George\'s Medical University, Lucknow, Uttar Pradesh, India
  • Article keywords
    Cervical carcinoma, Metastasis, Synchronous, Thyroid

    Abstract

    Aim: To describe a rare case of synchronous carcinoma cervix metastasizing to the thyroid, while the patient being of therapy for primary cancer. Background: Metastasis to thyroid primarily occurs from lung, kidney, gastrointestinal tract (GIT), and head and neck. Cervix cancer metastasis to thyroid had been rarely reported. Case description: We report an unsealed case of carcinoma cervix metastasizing to the thyroid gland, while being on concurrent chemoradiotherapy for primary malignancy and total thyroidectomy was performed as palliative management. Pathological examination confirmed the thyroid lesion as metastasizing squamous cell carcinoma from the cervix. The postoperative period was uneventful and the patient was referred to radiotherapy department but later developed thrombosis in major neck veins and developed the superior vena cava syndrome. The patient finally succumbed to the disease after 3 weeks. Conclusion: Very few cases of cervix cancer metastasis to thyroid have been reported so far. Synchronous metastasis in such cases is even rarer. Hence, any patients who presents with palpable nodules in the thyroid and have a history of a previous malignancy must be considered for metastatic disease and in female patients the possibility of metastasis from the cervix should be considered and managed as well as evaluated accordingly. Clinical significance: Synchronous metastatic growth in the thyroid is known to have a poor prognosis and although total thyroidectomy is not recommended in metastatic disease, but can be performed as a part of palliative treatment.

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