Emergency Imaging Ram Vaidhyanath, Mandip K Heir
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First principles of emergency imagingchapter 1

 
1.1 Imaging modalities
 
Plain radiographs
The discovery of X-rays by German physicist Wilhelm Conrad Roentgen in 1885 has profoundly influenced medical diagnosis and treatment. Radiographs are used in nearly 70% of diagnostic imaging examinations.
 
Principles
Radiographs are produced when X-rays pass through a part of the body and the resultant image is captured on a film or imaging plate. The image on the film is the result of the interaction of the X-rays with various tissues of the body part imaged. The amount the X-rays penetrate the body tissue is dependent on the density of the tissue. For example, bone, which has a higher density than soft tissue, allows fewer X-rays to pass through it and hence appears ‘white’, whereas soft tissue allows more X-rays to pass through and appears dark.
 
Terminology
 
Radiolucent
Permitting the passage of X-rays with little attenuation and hence almost entirely invisible on X-ray and under fluoroscopy.
 
Radiopacity
The property of being relatively resistant to the passage of X-rays.
 
Advantages
  • X-rays can be used to produce an image of most body parts
  • Easily available, even by the bedside, in the emergency department and in operating theatres2
 
Disadvantages
  • X-rays provide limited information
  • Radiation exposure
 
Ultrasound
 
Principles
Ultrasound is an imaging technique that uses high-frequency sound waves and their echoes. The ultrasound machine transmits high-frequency (1 to 15 megahertz (MHz)) sound pulses into the body using a probe. Some of the sound waves reflect back to the probe, while some travel on further. The reflected waves are detected by the probe and relayed to the machine. The machine calculates the distance from the probe to the tissue using the speed of sound in tissue (1540 m/s) and the time of each echo's return. This is converted into two-dimensional grayscale images.
 
Colour Doppler
Doppler echoes are usually displayed with grayscale brightness corresponding to their intensity. In colour Doppler, echoes are displayed with colours corresponding to the direction of flow that their positive or negative Doppler shifts represent (towards or away from the transducer). The brightness of the colour represents the intensity of the echoes.
 
Terminology
 
Anechoic
A structure that does not produce any internal echoes.
 
Hypoechoic
A relative term used to describe an area that has decreased brightness of echoes relative to an adjacent structure.
 
Hyperechoic
Also a relative term, used to describe a structure that has increased brightness of echoes relative to an adjacent structure.3
 
Advantages
  • Relatively safe
  • Inexpensive
  • Readily available by the bedside
 
Disadvantages
  • Heavily operator-dependent
  • Limited use in examining bones and deep structures of the body (e.g. the retroperitoneum)
 
Fluoroscopy
 
Principle
Fluoroscopy is a common technique used to obtain real-time images of moving body parts and internal structures of a patient compared to static radiographic examinations. In the context of emergency imaging, fluoroscopy is mostly used in paediatric patients to look for upper or lower gastrointestinal (GI) obstructions. It is also used for hydrostatic reduction of intussusception.
 
Computed tomography
 
Principles
Computed tomography (CT) uses multiple thin beams of X-rays that pass through a desired volume (part of the body being scanned) from multiple angles (usually over 180 degrees). As the X-rays penetrate the body, the X-ray beams will be attenuated, depending on the type of tissue they have travelled through. On the opposite side from where the X-rays originate, there is an array of detectors measuring the amount of X-rays that have travelled through the volume. This allows determination of the attenuation of individual beams as they pass through the volume.4
Table 1.1   Radiation risk of undergoing common X-ray, IVU (intravenous urogram) and CT (computed tomography) examinations.
Examination
Equivalent period of natural back-ground radiation
Estimated lifetime additional risk of cancer per examination
Chest, arms, legs, hands, feet Teeth
A few days
Negligible; less than 1 in 1,000,000
Skull, head, neck
A few weeks
Minimal; 1 in 1,000,000 to 1 in 100,000
Hip, spine, abdomen, pelvis
CT scan of head
A few months to a year
Very low; 1 in 100,000 to 1 in 10,000
Kidneys and bladder (IVU)
CT scan of chest
CT scan of abdomen
A few years
Low; 1 in 10,000 to 3 in 1,000
A computer system assigns a Hounsfield unit to each part of the volume based on the attenuation. The Hounsfield unit relates to the composition of the tissue that has been imaged, representing its density. Hounsfield units range from −1000 (air), which is not dense, to +1000 (cortical bone), which is very dense. CT is very good at discriminating between different types of tissue, including soft tissues (such as adipose and muscular tissue), even though they have similar densities.
 
Terminology
 
Isodense
Having a density similar to that of another or adjacent tissue, e.g. isodense subdural haematoma.
 
Hypodense
Appears less dense than the surrounding tissue, e.g. fat is hypodense when compared to bone on a CT image.
 
Hyperdense
Appears denser than adjacent tissue, e.g. fresh blood is hyperdense.
 
Advantages
  • Relatively inexpensive compared with magnetic resonance imaging (MRI)5
  • Accurate, three-dimensional data including attenuation information
  • Rapid acquisition of data
 
Disadvantages
  • Relatively high amount of ionising radiation per scan
  • Subject to artefacts due to patient movement
  • Contrast required for certain structures, particularly vessels. Some patients may have an anaphylactic response to intravenous contrast, which may occasionally be fatal
 
MRI
 
Principles
An MRI scanner applies a strong magnetic field to an area of interest. Hydrogen atoms present in most tissue placed within this field will mostly align parallel to the external magnetic field. As they align they also spin like a spinning top (precess). Electromagnetic radiation or a radio-frequency pulse is then applied to the precessing nuclei. When the electromagnetic field is turned off, the nuclei will return to their original precession around the external magnetic field. This involves two processes: T1 and T2 relaxation. The information is then converted into an image by computers in the MRI scanner.
 
Terminology
T1-weighted images convey the longitudinal relaxation time of tissues, whereas T2-weighted images depict the transverse relaxation time.
 
Hyperintense
Brighter than adjacent tissue, e.g. water is hyperintense on T2 images and fat is hyperintense on T1 images.6
 
Hypointense
Darker than adjacent tissue, e.g. water is hypo-intense on T1 images.
 
Advantages
  • Superb contrast between different soft tissues
  • Higher resolution than CT
  • No ionising radiation
 
Disadvantages
  • As the diameter of the scanner is quite small, patients may feel claustro-phobic
  • Longer examination time when compared to CT
  • Contraindicated in patie-nts with pacemaker
 
1.2 Use of contrast media
Body structures with different densities (i.e. on a chest X-ray the difference between the high-density bone and low-density air provides a contrast) are well seen on plain radiographs and CT. However, it is not possible to distinguish structures with similar density or average atomic numbers. In such cases, a contrast medium is used to improve the contrast between different organs, either by changing the density of the organ (e.g. air in the large bowel in colonography) or increasing the attenuation and Hounsfield unit by injecting a substance such as an iodine-containing contrast medium.
Common radiological investigations that involve the use of contrast media include CT, MRI, intravenous urography (IVU), arteriography and GI tract studies. Radiological contrast media are usually water-soluble with only a small percentage in suspension form. The contrast media most commonly used in emergency imaging are administered intravenously (IV).
 
 
Contrast administration
When a power injector is used, a 22G or larger needle/cannula 1.25 – 1.5 inch length is preferred for IV contrast injection. It is advisable to obtain a good backflow of blood to test adequate positioning of the needle in the vein.7
Table 1.2   Possible reactions to contrast administration and their management.
Mild
Nausea, warmth, pallor, flushing (these are normal physiological responses to contrast injection and do not require intervention)
Cough, headache, dizziness, vomiting, anxiety, altered taste, itching, chills, shaking, sweats, rash
Signs and symptoms appear self-limiting without evidence of progression. Requires observation (15–20 mins) to confirm resolution and/or lack of progression but usually no treatment. Patient reassurance is usually helpful.
Moderate
Severe urticaria, hypotension, bronchospasm, laryngeal oedema
Oral/IM/IV H1 antihistamine IV fluids – normal saline O2 through mask
Adrenaline 1:1000–0.5 ml IM Beta2 agonist through inhalers
Severe
Laryngeal oedema, profound hypotension, unresponsiveness, convulsions, clinically manifested arrhythmias, cardiopulmonary arrest
Call for resus team
Suction airway if necessary
Elevate legs if hypotensive
O2 through mask
Adrenaline 1:1000–0.5 ml IM
Diphenhydramine 25–50 mg IV
Adequate positioning of the cannula in the vein is then checked again by flushing 10 ml of saline into the vein before delivering the injection of contrast.
Essential information to establish before the administration of IV contrast includes:
  • A history of previous contrast reaction
  • Asthma
  • Renal problems
  • Diabetes
  • Metformin therapy
 
Contrast reactions
Adverse reactions to iodinated contrast media are extremely low, but do occur. They are broadly classified as:8
  • Minor: flushing, nausea, vomiting, pruritis, mild rash, arm pain
  • Moderate: more severe urticaria, facial oedema, hypotension, bronchospasm
  • Severe: hypotensive shock, laryngeal oedema, convulsions, respiratory and cardiac arrest
 
Renal function
Contrast media can result in acute renal failure, leading to morbidity and mortality. Contrast media are toxic to the renal tubular ceells as well as resulting in renal ischaemia. Therefore, prior to administration of contrast, patient risk factors such as hypertension, diabetes, and pre-existing renal insufficiency need to be determined.
The development of contrast medium-induced nephropathy is low in people with normal renal function, varying from 0% to 5%. Pre-existing renal impairment increases the frequency of this complication. The estimated glomerular filtration rate (eGFR) is more sensitive than serum creatinine levels for assessing the state of renal function before administration of contrast media. A guide level of an eGFR below 60 ml/min/1.73 m2 has been used to indicate renal impairment.