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Key Clinical Topics in Anaesthesia
Roger Langford, David Ashton-Cleary
Airway assessment
Key points
History
Examination
Specific airway examination
Prediction tools
Investigations
Related topics of interest
Airway – difficult and failed intubation
Key points
Causes of difficult intubation
Grading difficult laryngoscopy
Management of difficult intubation
Alternative intubating devices
‘Front of neck’ techniques
Failed intubation
Related topics of interest
Airway – the emergency airway
Key points
Problems
Clinical features
Investigations
Anaesthetic management
Trauma airway
Infection
Tumour
Extubation
Related topics of interest
Airway – the shared airway
Key points
Problems
Investigations
Anaesthetic management
Related topics of interest
Awake intubation
Key points
Indications
Contraindications
Anaesthetic management
Assessment and premedication
Conduct of anaesthesia
Local anaesthetic techniques
Topical anaesthesia
Nerve blocks
Sedation
Related topics of interest
Awareness and depth of anaesthesia
Key points
Incidence
Causes and risk factors
Assessment and management
Preoperative
Intraoperative
Postoperative
Legal situation
Related topics of interest
Blood physiology
Key points
Red blood cells and haemoglobin
Oxygen carriage
CO2 carriage
Coagulation
Measurement of coagulation
Pharmacological haemostatic agents
Immune function
Cell-mediated functions
Non-cell-mediated functions
Related topics of interest
Blood transfusion and salvage
Key points
Types of blood transfusion
Homologous blood transfusion
Collection and storage media
Blood components (Figure 1)
Serious hazards of blood transfusion
Autologous blood transfusion options
Cell salvage
Anaesthetic management in patients requiring blood transfusion
Preoperative measures
Intraoperative and postoperative measures
Future trends
Related topics of interest
Burns
Key points
Definition of a burn
Initial assessment and resuscitation
Secondary management
Anaesthetic management
Related topics of interest
Cardiac anaesthesia – congenital heart disease
Key points
Problems
Classification
Investigations
Anaesthetic management
Special considerations
Pulmonary hypertension
Infective endocarditis
Bleeding
Fluids and heart failure
Shunt
Obstetric patients
Related topics of interest
Cardiac anaesthesia – valvular heart disease
Key points
Problems
Clinical features
Investigations
Anaesthetic management
Aortic stenosis (AS)
Aortic regurgitation (AR)
Mitral stenosis (MS)
Mitral regurgitation (MR)
Other valvular lesions
Replacement valves
Antibiotic prophylaxis for infective endocarditis (IE)
Related topics of interest
Cardiac dysrhythmia
Key points
Types of dysrhythmia
Preoperative causes
Perioperative causes
Perioperative management
Postoperative care
Cardioversion
Anaesthetic management for elective cardioversion
Related topics of interest
Cardiac pacemakers
Key points
Problems
Anaesthetic management
Preoperative
Intraoperative
Postoperative
Related topics of interest
Cardiac surgery
Key points
Problems
Cardiovascular
Respiratory
Neurological
Endocrine
Renal
Antiplatelet therapy
Cardiopulmonary bypass
Anaesthetic management
Preoperative
Intraoperative
Postoperative
Related topics of interest
Coronary artery disease
Key points
Pathology
Problems
Anaesthetic management
Anaesthetic technique
Postoperative care
Treatment of myocardial ischaemia
Related topics of interest
Day surgery
Key points
Definition
National guidelines and targets
Advantages of day surgery
Controversies regarding day surgery
Organisational issues
Patient selection
Principles of perioperative care
Role of audit
Related topics of interest
Dental anaesthesia
Key points
Problems
Techniques
Local anaesthesia
Sedation
General anaesthesia
Anaesthetic management
Learning difficulties
Extraction of impacted molars
Related topics of interest
Diabetes
Key points
Problems
Clinical features
Investigations
Treatment
Anaesthetic management
Related topics of interest
Drug allergy and adverse reactions
Key points
Adverse drug reaction (ADR)
Clinical features
Treatment
Risk factors
Investigations
Blood tests
Skin tests
Follow-up
Related topics of interest
Elderly patients
Key points
Problems
Anaesthetic management
Assessment and premedication
Conduct of anaesthetic
Postoperative care
Related topics of interest
Electroconvulsive therapy
Key points
Problems
Physiological effects of ECT
Remote site anaesthesia
Consent issues
Anaesthetic management
Preoperative
Intraoperative
Postoperative
Related topics of interest
Emergency anaesthesia
Key points
Problems
Anaesthetic management
Related topics of interest
Endocrine disease
Key points
Adrenal disease
Adrenocortical excess
Cushing's syndrome
Cushing's disease
Problems
Adrenocortical deficiency
Acute
Chronic
Problems
Hyperaldosteronism
Primary (Conn's syndrome)
Problems
Anaesthetic management
Assessment and premedication
Conduct of anaesthesia
Pituitary disease – acromegaly
Problems
Anaesthetic management
Carcinoid syndrome
Problems
Anaesthetic management
Assessment and premedication
Conduct of anaesthesia
Postoperative care
Related topics of interest
Ethics and consent
Key points
Approaches to medical ethics
Discussing medical ethics
Guidance and consensus
Consent
Valid consent
Capacity
The Mental Capacity Act (MCA) 2005 (England and Wales)
‘Proxy’ decision makers
Advance decisions (advance directive)
Minors
Emergencies
Related topics of interest
Gas embolism
Key points
Predisposing factors
Prevention
Diagnosis
Monitoring
Treatment
Related topics of interest
Gynaecology
Key points
Problems
Anaesthetic management – minor procedures
Preoperative
Intraoperative
Postoperative
Anaesthetic management – moderate/major procedures
Preoperative
Intraoperative
Postoperative
Related topics of interest
Human factors in patient safety
Key points
Specific examples
ANTS
Checklists and care bundles
Simulation
Error reporting
Related topics of interest
Hypertensive disease
Key points
Problems
Causes of perioperative hypertension
Hypertension and perioperative risk
Perioperative management
Related topics of interest
Infection prevention and control
Key points
Main aspects
Organisational
Individual
Specific items
Antibiotics and prophylaxis
Hand hygiene
Infection nursing protocols
Related topics of interest
Infectious diseases
Key points
Problems
Specific disorders
HIV
TB
Hepatitis B and C
Others
Management to reduce transmission
Related topics of interest
Lasers in surgery
Key points
Problems
Anaesthetic management
Related topics of interest
Liver disease and anaesthesia
Key points
Problems
Cardiovascular
Respiratory
Renal
Haematology
Neurology
Pharmacology
Ascites
Metabolic
Anaesthetic management
Preoperative assessment
Intraoperative
Postoperative care
Related topics of interest
Liver resection surgery
Key points
Problems
Conduct of surgery
Anaesthetic management
Preoperative
Intraoperative
Analgesia
Open surgery
Laparoscopically assisted procedures
Postoperative care
Related topics of interest
Major abdominal surgery
Key points
Problems
Anaesthetic management
Preoperative assessment
Intraoperative management
Postoperative care
Enhanced recovery programmes
Related topics of interest
Malignant hyperpyrexia
Key points
Physiology
Trigger agents
Associated conditions
Presentation
Management
Investigation
Management of patients with known/suspected MH
Related topics of interest
Minimally invasive surgery
Key points
Problems
Equipment
Physiological changes and other considerations
Pneumoperitoneum
Positioning
Gas insufflation
Complications
Related topics of interest
Muscular diseases
Key points
Dystrophies
Problems
Anaesthetic management
Assessment and premedication
Conduct of anaesthesia
Postoperative care
Myotonias
Problems
Anaesthetic management
Assessment and premedication
Conduct of anaesthesia
Postoperative care
Mitochondrial and metabolic myopathies
Related topics of interest
Myasthenia gravis
Key points
Problems
Clinical features
Investigations
Treatment
Anaesthetic management
Myaesthenic crisis
Cholinergic crisis
Related topics of interest
National audit
Key points
NCEPOD
Knowing the risk: a review of the perioperative care of surgical patients (2011)
Elective and emergency surgery in the elderly: an age old problem (2010)
Trauma: who cares? (2007)
Abdominal aortic aneurysm: a service in need of surgery? (2005)
An acute problem (2005)
Who operates when? I (1997) and II (2003)
CMACE
National audit projects
NAP1: Supervisory role of consultant anaesthetists 2003
NAP2: Place of mortality and morbidity review meetings 2003
NAP3: Major complications of central neuraxial block in the United Kingdom (2009)
NAP4: Major complications of airway management in the United Kingdom (2011)
NAP5: Accidental awareness during general anaesthesia in the United Kingdom (2013)
NAP6: Anaphylaxis
ICNARC
TARN
Related topics of interest
Neuroanaesthesia – subarachnoid haemorrhage
Key points
Problems
Endovascular platinum coiling
Surgical clipping of aneurysm neck
Clinical features
Investigations
Treatment
Anaesthetic management
Preoperative
Intraoperative
Coiling
Clipping
Postoperative care
Related topics of interest
Neuroanaesthesia – traumatic brain injury
Key points
Treatment
Management of raised ICP
Management of seizures
Reduction in cerebral metabolic requirements
Anaesthetic management
Airway
Breathing
Circulation
Disability
Related topics of interest
Neuroanaesthesia – tumours
Key points
Clinical features
Anaesthetic management
Preoperative
Intraoperative
Postoperative care
Special circumstances
Related topics of interest
Neurological disease – demyelinating and neurodegenerative diseases
Key points
Guillain–Barré syndrome
Anaesthetic management
Multiple sclerosis
Problems
Anaesthetic management
Motor neurone disease
Problems
Anaesthetic management
Parkinson's disease
Problems
Anaesthetic management
Related topics of interest
Neurological disease – epilepsy
Key points
Problems
Anaesthetic management
Assessment and premedication
Conduct of anaesthesia
Postoperative care
Seizures during anaesthesia
Causes
Management
Status epilepticus
Related topics of interest
Nutrition
Key points
Malnutrition
Metabolic response to surgery and insulin resistance
Carbohydrate loading
The immunological role of the intestine
Immunonutrition
Related topics of interest
Obesity – incidental surgery
Key points
Problems
Cardiovascular
Respiratory
Gastrointestinal
Endocrine
Investigations
Anaesthetic management
Preoperative
Intraoperative
Postoperative
Related topics of interest
Obesity – surgery for weight reduction
Key points
Types of surgery
Restrictive
Malabsorptive
Investigations
Anaesthetic management
Preoperative
Intraoperative
Postoperative
Related topics of interest
Obstetrics – anaesthesia
Key points
Problems
Hypotension
Inadequate anaesthesia
Anaesthetic management
Single-shot spinal
Epidural top-up
Combined spinal epidural
General anaesthesia
Related topics of interest
Obstetrics – analgesia
Key points
Pharmacokinetics and pharmacodynamics
In labour
Nonpharmacological pain relief
Pharmacological pain relief
Regional techniques
After caesarean section
Perioperative
Postoperative
Related topics of interest
Obstetrics – emergencies
Key points
Major haemorrhage
Pre-eclampsia and eclampsia
Local anaesthetic toxicity
Failed intubation
Maternal sepsis
Maternal cardiac arrest
Magnesium toxicity
High regional blockade
Tocolysis
Related topics of interest
Oesophagectomy
Key points
Surgical approach
Anaesthetic management
Preoperative management
Intraoperative management
Postoperative care
Related topics of interest
Ophthalmology
Key points
Problems
Investigations
Anaesthetic management
Regional techniques
Sedation
General anaesthesia
Related topics of interest
Organ donation
Key points
Circumstances of donation
Donor care
Retrieval process
Related topics of interest
Orthopaedics – elective
Key points
Lower limb prosthetic surgery
Upper limb surgery
Limb tourniquets
Related topics of interest
Orthopaedics – emergency
Key points
Hip fracture surgery
Open fractures
Compartment syndrome
Fat embolism
Paediatric fractures
Related topics of interest
Paediatric anaesthesia – basic concepts
Key points
Airway and respiratory management
Mode of ventilation
Prevention of hypoxia
Fluid and electrolyte replacement therapy
Blood glucose
Temperature maintenance
Drug dosing
Related topics of interest
Paediatric anaesthesia – basic practical conduct
Key points
Safe provision of paediatric services
Preoperative assessment
Premedication
Starvation times
Useful formulae
Perioperative management
Induction
Maintenance
Airway
Fluids
Temperature regulation
Emergence
Postoperative care
Child protection
Related topics of interest
Paediatric anaesthesia – neonatal surgery
Key points
Congenital diaphragmatic hernia
Perioperative considerations
Inguinal hernia
Perioperative considerations
Postoperative care
Intestinal obstruction
Perioperative considerations
Abdominal wall defects
Preoperative considerations
Conduct of anaesthesia
Postoperative care
Necrotising enterocolitis (NEC)
Preoperative considerations
Conduct of anaesthesia
Tracheoesophageal fistula and oesophageal atresia
Preoperative considerations
Conduct of anaesthesia
Postoperative
Related topics of interest
Paediatric anaesthesia – pyloric stenosis
Key points
Disease summary
Problems
Diagnosis
Treatment
Preoperative resuscitation
Surgical treatment
Anaesthetic management
Postoperative care
Related topics of interest
Paediatric emergency airways
Key points
Laryngospasm
Prevention
Treatment
Inhaled foreign body
Infectious causes
Bleeding after adenotonsillectomy
Burns
Paediatric airway guidelines
Related topics of interest
Pain – acute management
Key points
Assessment
Preoperative
Postoperative
Assessment scales
Unidimensional scales
Other assessment tools
Anaesthetic management
Acute pain team
Multimodal analgesia
Opioids
Patient-controlled analgesia (PCA)
Atypical analgesia
Ketamine
Lidocaine
Clonidine
Gabapentin and pregabalin
Related topics of interest
Pain – chronic management
Key points
Problems
Clinical features
Treatment
Anaesthetic management
Opioid tolerance and withdrawal
Adjuvant analgesics
Prevention of chronic postsurgical pain
Related topics of interest
Patient transfer and transport
Key points
Problems
Generic concerns
Journey-specific concerns
Other issues
Preparedness
Personal safety and comfort
Related topics of interest
Perioperative fluid management
Key points
Preoperative considerations
Intraoperative considerations
Type of fluid administered
Postoperative considerations
Special cases
Related topics of interest
Phaeochromocytoma
Key points
Problems
Anaesthetic management
Preoperative assessment
Preoperative preparation
Perioperative management
Postoperative care
Related topics of interest
Plastic surgery
Key points
Problems
Investigations
Anaesthetic management
Preoperative
Intraoperative
Postoperative care
Related topics of interest
Polytrauma
Key points
Problems
Anaesthetic management
Airway
Breathing
Circulation
Coagulopathy in trauma
Related topics of interest
Positioning for surgery
Key points
Patient injury
Pressure necrosis
Nerve injury
Tendon and joint injury
Cardiovascular system
Respiratory system
Gastrointestinal tract
Central nervous system
Eyes
Related topics of interest
Postoperative nausea and vomiting
Key points
Problems
PONV physiology
Risk stratification
Treatment
Anaesthetic management
Related topics of interest
Preoperative assessment – risk evaluation
Key points
Problems
Specific scores
ASA classification
Revised Cardiac Risk Index
ACC/AHA guidelines
Functional capacity and CPET
P-POSSUM
Respiratory scoring systems
Related topics of interest
Preoperative assessment – risk modification
Key points
Problems
Specific elements
Preassessment
Cardiac disease
Fitness
Obesity
Smoking
ERAS
Beta-blockers
WHO checklist
Related topics of interest
Procedural sedation
Key points
Problems
Guidelines in sedation practice
Anaesthetic management
Special circumstances
Related topics of interest
Radiology – anaesthesia for imaging
Key points
MRI
Problems
Indications for general anaesthesia
Anaesthetic management
Assessment and premedication
Conduct of anaesthesia
Postoperative care
CT
Issues specific to CT scanning
Related topics of interest
Radiology – interventional radiology
Key points
Vascular radiology
Neuroradiology
Cardiac IR
Biliary tree and renal radiology
Trauma and haemorrhage-control radiology
Interventional MRI
Related topics of interest
Regional anaesthesia – central neuraxial blockade
Key points
Potential benefits of CNBs
Indications
Contraindications
Absolute
Relative
Complications
Very common (1 in 10) or common (1 in 100)
Rare (1 in 10,000) or very rare (1 in 100,000) complications
Anaesthetic management
Red flags
Management of post dural puncture headache
Related topics of interest
Regional anaesthesia – plexus and peripheral nerve blocks
Key points
Indications
Contraindications
Absolute contraindications
Relative contraindications
Continuous nerve infusion catheters
Practical aspects of RA
Surroundings
Awake or asleep?
Nerve localisation
Local anaesthetic action
Complications
Nerve injury
Local anaesthetic toxicity
Presentation
Management
Related topics of interest
Renal disease – acute kidney injury
Key points
Problems
Anaesthetic management
Altered drug pharmacokinetics
Preoperative assessment
Conduct of anaesthesia
Postoperative care
Related topics of interest
Renal disease – chronic kidney disease
Key points
Problems
Anaesthetic management
Altered drug pharmacokinetics
Preoperative assessment
Vascular access
Conduct of anaesthesia
Postoperative care
Related topics of interest
Respiratory – acute respiratory distress syndrome
Key points
Anaesthetic management
Preoperative
Intraoperative
Postoperative
Related topics of interest
Respiratory – asthma
Key points
Problems
Surgery for patients with concurrent asthma
Preoperative assessment
Anaesthetic management
Management of acute severe asthma
Related topics of interest
Respiratory – chronic obstructive pulmonary disease
Key points
Problems
Anaesthetic management
Preoperative assessment
Conduct of anaesthesia
Pulmonary hypertension
Postoperative care
Related topics of interest
Respiratory – invasive ventilation strategies
Key points
Principal modes of ventilation
Intermittent positive pressure ventilation (IPPV)
Other modes and strategies
Airway pressure release ventilation (APRV)
Inverse ratio ventilation (IRV)
Proning
High-frequency oscillatory ventilation (HFOV)
Extracorporeal membrane oxygenation (ECMO)
Consequences of mechanical ventilation
Protective ventilation
Weaning strategies
Inspiratory pressure support
Inspiratory volume support
Intermittent mandatory ventilation (IMV) and synchronised intermittent mandatory ventilation (SIMV)
Proportional assist ventilation (PAV)
Tracheostomy
Related topics of interest
Rheumatoid arthritis
Key points
Problems
Clinical features
Investigations
Treatment
Drugs for symptomatic relief
Disease modifying drugs
Anticytokine agents (biological agents)
Anaesthetic management
Postoperative
Related topics of interest
Sickle cell disease
Key points
Problems
Anaesthetic management
Assessment and premedication
Conduct of anaesthesia
Postoperative care
Related topics of interest
Sleep apnoea
Key points
Problems
Anaesthetic management
Assessment and premedication
Conduct of anaesthetic
Postoperatively
Related topics of interest
Smoking
Key points
Problems
Carbon monoxide
Investigations
Smoking cessation
Related topics of interest
Spinal cord injury
Key points
Problems
Airway
Breathing
Circulation
Autonomic dysreflexia
Neurology
Other
Related topics of interest
Spinal surgery
Key points
Problems
Anaesthetic management
Preoperative
Intraoperative
Postoperative
Related topics of interest
Substance abuse
Key points
Problems
Clinical features
Investigations
Treatment
Anaesthetic management
Related topics of interest
Systemic inflammatory response syndrome and sepsis
Key points
Problems
General principles for anaesthesia
Ventilatory management
Haemodynamic management
Infection management
General care
Controversial treatments
Related topics of interest
Thermoregulation
Key points
Temperature measurement
Hypothermia
Effects of anaesthesia on temperature
Strategies for minimising heat loss
Hyperthermia
Increased heat production
Decreased heat loss
Pathophysiology
Management
Neuroleptic malignant syndrome
Related topics of interest
Thoracic surgery
Key points
Problems
Investigations
Anaesthetic management
Double-lumen tubes
One-lung ventilation
Hypoxaemia
Analgesia
Postoperative management
Related topics of interest
Thyroid and parathyroid surgery
Key points
Problems
Clinical features
Investigations
Treatment
Anaesthetic management
Postoperative problems
Hypocalcaemia
Vocal cord palsy
Tracheomalacia
Thyrotoxic storm
Bleeding
Related topics of interest
Total intravenous anaesthesia and target-controlled infusions
Key points
Volume of distribution (Vd)
Clearance
Infusion kinetics
Context-sensitive half-time
Target-controlled infusions
TIVA and TCI
Infusion pumps
Related topics of interest
Urology
Key points
Prostate and bladder surgery
Problems
Anaesthetic management
Assessment and premedication
Conduct of anaesthesia
TURP syndrome
Postoperative care
Renal surgery
Paediatric urology
Related topics of interest
Vascular access
Key points
Peripheral
Central
Complications of central access
Early
Late
Emergency access
Related topics of interest
Vascular surgery – aortic aneurysmal disease
Key points
Problems
Clinical features
Investigations
Treatment
Anaesthetic management
EVAR
Open repair
Postoperative
Related topics of interest
Vascular surgery – occlusive disease
Key points
Problems
Clinical features
Investigations
Treatment
Anaesthetic management
Carotid surgery
PVD surgery
Related topics of interest
Venous thromboembolism – prevention and treatment
Key points
Prevention
Preoperative
Peri- and postoperative
Mechanical
Pharmacological
Diagnosis
Therapeutic treatment of VTE
Pulmonary embolism
Clinical presentation
Diagnosis
CT pulmonary angiography
V/Q scanning
D-dimer
Management
Related topics of interest
Venous thromboembolism – risk
Key points
Anaesthetic factors
Related topics of interest
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