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Practical Pediatric Endocrinology
PSN Menon, Anurag Bajpai, Jyoti Sharma
SECTION 1: GROWTH AND PITUITARY
1:
Short stature
CAUSES
Diagnostic criteria
EVALUATION
MANAGEMENT
Nutritional Therapy
Constitutional Delay
Growth Hormone Therapy (Please refer to chapter 3)
2:
Tall stature
CAUSES
HYPOGONADISM
Enzymatic Defects
Chromosomal defect
Genetic syndrome
Hyperthyroidism
EVALUATION
MANAGEMENT
Constitutional tall stature
Precocious puberty
Pituitary lesion
3:
Growth hormone deficiency
CAUSES
CLINICAL FEATURES
EVALUATION
MANAGEMENT
Growth hormone
Follow-up
Clinical
Investigations
Discontinuation of Treatment
4:
Panhypopituitarism
CAUSES
POINTERS TO PITUITARY INSUFFICIENCY
EVALUATION
MANAGEMENT
Adrenal
Thyroid
Vasopressin
Hypogonadism
For fertility
Follow-up
5:
Diabetes insipidus
CAUSES OF POLYURIA
EVALUATION
MANAGEMENT
Central diabetes insipidus
SECTION 2: THYROID
6:
Hypothyroidism
CAUSES
Pointers to hypothyroidism
MANAGEMENT
Congenital hypothyroidism
Primary hypothyroidism
Secondary hyopothyroidism
Duration of Therapy
7:
Hyperthyroidism
CAUSES
Pointers to hyperthyroidism
EVALUATION
MANAGEMENT
Graves disease
8:
Goitre and solitary thyroid nodule
WHO grading
Evaluation
MANAGEMENT
Solitary thyroid nodule
Indicators of malignancy
Investigations
MANAGEMENT
Malignancy
SECTION 3: CALCIUM METABOLISM
9:
Hypocalcemia
CAUSES
EVALUATION
History
Examination
Investigations
Level I
Level II
Association, complications
MANAGEMENT
Acute
Longterm
Follow-up
10:
Hypercalcemia
CAUSES
EVALUATION
History
Examination
Investigations
Level I
End organ damage
For hyperparathyroidism
MANAGEMENT
Acute
Chronic
Hyperparathyroidism
11:
Refractory rickets
CAUSES
EVALUATION
History
Examination
Investigations
Level I
Level II
MANAGEMENT
Renal tubular acidosis
Hypophosphatemic rickets
SECTION 4: PANCREAS
12:
Type I diabetes mellitus
13:
Diabetic ketoacidosis
Pointers to diabetic ketoacidosis
MANAGEMENT
Switch over
14:
Hypoglycemia
CAUSES
EVALUATION
MANAGEMENT
Acute
Long term
SECTION 5: ADRENAL DISORDERS
15:
Cushing syndrome
CAUSES
MANAGEMENT
Surgical
Medical management
16:
Adrenal insufficiency
CAUSES
Pointers to adrenal insufficiency
EVALUATION
History
Examination
Investigation
Level I
Level II
Etiology
MANAGEMENT
Addisonian Crisis
Corticosteroids
Fludrocortisone (Tab Florinef- 0.1 mg)
Followup
17:
Congenital adrenal hyperplasia
Pointers to congenital adrenal hyperplasia
MANAGEMENT
Prenatal
Acute crisis
Long term
Classical virilizing 21-hydroxylase deficiency
Non-classical CAH
SECTION 6: SEXUAL DEVELOPMENT AND DIFFERENTIATION
18:
Precocious puberty
CAUSES
EVALUATION
History
Examination
Investigations
Endocrine
Etiology
Complications
MANAGEMENT
Specific
Central isosexual precocious puberty
Premature thelarchae
19:
Delayed puberty
CAUSES
EVALUATION
MANAGEMENT
Hypergonadotropic hypogonadism
Hypogonadotropic hypogonadism
Constitutional delay
20:
Turner Syndrome
EVALUATION
CLINICAL
INVESTIGATIONS
Initial
Association
MANAGEMENT
Growth Hormone
Hormone Replacement (Refer page 92)
Follow-up
21:
Ambiguous genitalia
EVALUATION
MANAGEMENT
Sex Assignment
Indications for gonadectomy
22:
Micropenis
CAUSES
EVALUATION
MANAGEMENT
Cryptorchidism
Bilateral cryptorchidism
MANAGEMENT
hCG
23:
Gynecomastia
CAUSES
EVALUATION
MANAGEMENT
Medical- No treatment if size less than 4 cm
Surgery
24:
Hirsutism
CAUSES
POINTERS TO HIRSUTISM
EVALUATION
CLINICAL
INVESTIGATIONS
MANAGEMENT
Specific
Non Specific
SECTION 7: ELECTROLYTE AND ACID BASE
25:
Hyponatremia
CAUSES
EVALUATION
MANAGEMENT
26:
Hypernatremia
CAUSES
EVALUATION
MANAGEMENT
Nonspecific
Specific
27:
Hypokalemia
CAUSES
EVALUATION
MANAGEMENT
Nonspecific
Specific
28:
Hyperkalemia
CAUSES
EVALUATION
MANAGEMENT
Nonspecific
Specific
29:
Metabolic acidosis
CAUSES
EVALUATION
MANAGEMENT
Indications
Requirement
Specific
30:
Metabolic alkalosis
CAUSES
EVALUATION
MANAGEMENT
General
Specific
SECTION 8: MISCELLANEOUS DISORDERS
31:
Obesity
CAUSES
EVALUATION
MANAGEMENT
General Measures
Behavior moification therapy
Intensive measures
32:
Endocrine hypertension
CAUSES
EVALUATION
MANAGEMENT
Nonspecific
Specific
APPENDICES
Appendices
APPENDIX 1
APPENDIX 2
SEXUAL MATURITY RATING (TANNERS)
APPENDIX 3
APPENDIX 4
INDEX
TOC
Index
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