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Bronchial Asthma in Children: A Clinical, Diagnostic and Management Primer
Keya R Lahiri
CHAPTER 1:
Definition, Pathophysiology and Severity
CHAPTER 2:
Early Diagnosis
CHAPTER 3:
Environment and Patient Education
CHAPTER 4:
Managing Acute/Severe Exacerbations of Asthma
IMPENDING RESPIRATORY FAILURE/RESPIRATORY FAILURE
Assessing Exacerbation
Pulmonary Score (PS Score)
Management of Acute/Acute Severe Asthma
When Child Reports to the Hospital
Steroids
Nonavailability of MDI/neb
If Improvement after 6 Hours
However if the Child Deteriorates
Important Points on Intubation
Ventilatory Management
Ventilator Mode
Newer Trends
General Principles and Goals for Managing Asthma Exacerbations
CHAPTER 5:
Managing Chronic Persistent Asthma
MANAGING CHRONIC PERSISTENT ASTHMA
(i) Corticosteroids
(ii) Nedocromil and Cromolyn Sodium
(iii) Bronchodilators
Ipratropium Bromide
Methylxanthines
CHAPTER 6:
Leukotriene Modifiers
LEUKOTRIENE MODIFIERS
Zileuton
Montelucast
Long-acting Inhaled β2 Agonist
Inhaled Corticosteroids
Local Adverse Events
Oral Candidiasis (Thrush)
Prevention and Treatment
Dysphonia
Prevention and Treatment
Reflex Cough and Bronchospasm
SYSTEMIC ADVERSE EFFECTS
Bone Metabolism/Osteoporosis
Prevention and Treatment
Disseminated Varicella
Prevention and Treatement
Hypothalamic Pituitary Axis (HPA) Function
Cataracts
Glucose Metabolism
How to Use a Peak Flow Meter?
5 Steps
Key Points in the Long-term Management of Asthmatic Children
Step Down
Step Up
CHAPTER 7:
Future Aspects of Therapeutic Strategies
FUTURE ASPECTS OF THERAPEUTIC STRATEGIES
A. Bronchodilators
B. Corticosteroids
C. Mediator Antagonists
Antihistamines
Antileukotrienes
D. Cytokine Modulators
a. Anti IL-5
b. Anti IL-4
c. Anti IL-13
d. Anti-TNF
e. Chemokine Inhibitors
E. Anti-inflammatory Cytokines
F. New Anti-inflammatory Drugs
G. Specific Anti-allergy Drugs
a. Cromones
b. Th2 Cell Inhibitors
c. Anti-IgE
Preventive Strategies
Gene Therapy
INDEX
TOC
Index
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