Broadly treatment depends in the symptoms expressed and whether the therapy is for aesthetic regions in patient not desiring pregnancy, for infertility or even to prevent long-term complications.

This book is not only focused recent concept of pathophysiology, diagnosis and long-term sequelae of PCOS but also highlighted treatment protocol in details. I hope and firmly believe that this book will be highly accepted by gynaecologist practicing infertility and reproductive medicine. It will also be helpful to undergraduate and postgraduate medical students for the preparation of their final examination.

Polycystic ovaries are related to metabolic sequelae. Amongst the late ones are obesity, diabetes mellitus that is associated with hyperinsulinemia cardiovascular disease, high LDL and hypertension (Balen 2001). These conditions represent a significant health problem in women. Familial aggregates of PCOS are well recognized (Legro et al 1995). There is evidence of the involvement of at least two genes in the aetiology of PCOS, the steroid synthesis gene CYP 11a and the insulin gene VNTR regulatory polymorphism. Apart from the association with infertility and endometrial cancer, the epidemiology of the cluster of metabolic sequelae of PCO could suggest that such sequelae are the result of PCO being present at a younger pre-menopausal age. Intriguingly, it has been suggested that PCO and PCOS can also be inherited from the father's side (Bennett et al 1997). The implications are therefore that we are dealing with a condition that has serious Public Health consequences and has a wide range of medical implications.

Author has highlighted the various aspects of PCOS including defination, pathophysiology, diagnosis, long-term sequelae and management of PCOS.

Very useful for practising gynaecologist interested in ART, and reproductive medicine.