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Essentials of Surgery
Sunil Chumber
SECTION 1: GENERAL SURGERY
1:
History of Surgery: An Enlightening Story
SURGERY IN ANCIENT AND MEDIEVAL TIMES
Ambroise Paré
John Hunter
Lord Joseph Lister
HISTORY OF MODERN SURGERY
Human Anatomy
Hemostasis in Surgery
Development of Anesthesia
Concepts of Asepsis
EVOLUTION OF SCIENTIFIC METHODS IN SURGERY DURING THE 19TH AND 20TH CENTURY
DEVELOPMENT OF SURGERY IN THE MODERN TIMES
Abdominal Surgery
Gastric Surgery
Surgery of the Gallbladder and the Biliary System
Surgery of the Pancreas
Surgery for Chronic Pancreatitis
Surgery for Pancreatic Tumor
Surgery of the Intestines
Surgery of Herniae
Thoracic Surgery
Laparoscopic Surgery
INDIAN CONTRIBUTION TO THE PRACTICE OF SURGERY
The Era of Sushruta
SURGEONS AND THE NOBEL PRIZE
2:
Response of the Body to Injury
INJURY AND SURGICAL STRESS
Trauma and Blood Volume
Volume Reduction, Hypoperfusion and the Low Flow State
Volume Reduction (Hypovolemia)
Low-Flow State
THE SYSTEMIC (PATHOPHYSIOLOGICAL) RESPONSE TO INJURY
Endocrine Response to Trauma
Glucocorticoids
Catecholamines
Aldosterone and Renin
Antidiuretic Hormone (ADH, Vasopressin)
Glucagon
Insulin
Growth Hormone
Gonadotropins and Sex Hormone
Prolactin
Endogenous Opioids
Metabolic Response to Trauma and Stress
Starvation and Trauma
Energy Requirements and Trauma
Catabolic State
Alimentation
CLINICAL COURSE AND RECOVERY FOLLOWING INJURY
Water and Electrolyte Changes
Sodium Disturbances
Potassium Disturbances
Acid-base Changes
Acidosis
Alkalosis
Change in Osmolality
Hyper-osmolarity
Hypo-osmolarity
Clinical Responses in Injury
Cardiovascular System
Renal System
Gastrointestinal System
Respiratory System
Central Nervous System
Coagulation System
3:
Shock
PATHOPHYSIOLOGY OF SHOCK
Cellular Changes
Neuroendocrine Changes
Hormonal Changes
Changes in Microcirculation
Metabolic Changes
Visceral Changes
Brain
Kidneys
Lungs
Coagulation System
Alimentary Tract
Liver
Heart
CLASSIFICATION OF SHOCK
Hypovolemic Shock
Cardiogenic Shock
Extracardiac Obstructive Shock
Distributive Shock
Neurogenic Shock
Septic Shock
Anaphylactic Shock
CLINICAL FEATURES OF SHOCK
MONITORING OF A PATIENT IN SHOCK
MANAGEMENT OF A PATIENT IN SHOCK
Resuscitation
Laboratory and Other Procedures
Position of the Patient
Fluids for Restoration of Intravascular Volume
Blood Transfusions
Arrest of Ongoing Losses
Bleeding
Antishock Garments
Pharmacological Support of Blood Pressure
Vasopressors
Levarterenol
Intra-aortic Balloon Pump (IABP)
Ventilation
Analgesia
Thrombolysis in Cardiogenic Shock
Septic Shock
Neurogenic Shock
Anaphylactic Shock
Multiple Organ Dysfunction Syndrome (MODS)
4:
Fluids, Electrolytes and Acid-base Balance
BASIC PHYSIOLOGY
ECF Ionic Concentration
Interstitial Concentrations
Intracellular Ionic Concentrations
Ionic Concentration in Various Body Secretions
DISORDERS OF FLUID AND ELECTROLYTE
Clinical Assessment of Fluid Volume Status
Maintenance Therapy
Extracellular Fluid Volume Contraction
Treatment
Antidiuretic Hormone (ADH) and Diabetes Inspidus
Extracellular Fluid Expansion
Sodium Disorders
Renal Handling of Sodium
Normal Water Diuresis
Hyponatremia
Types of Hyponatremia
Hyponatremia with ECF Depletion (Actual Sodium Depletion)
Syndrome of Inappropriate Vasopressin Secretion
Clinical Features of Hyponatremia
Management
Treatment of Acute Symptomatic Hyponatremia
Calculation of Desired (Negative) Water Balance
Treatment of Chronic Symptomatic Hyponatremia
Prognosis
Hypernatremia
Clinical Features
Management
Potassium Disorders
Hypokalemia
Clinical Features
Approach to Differential Diagnosis
Management
Hyperkalemia
Clinical Features
Management
Acute Hyperkalemia
Chronic Hyperkalemia
REGULATION OF ACID-BASE BALANCE
Basic Concepts and Terminology
Body Buffers
Renal Control of Acid-base Balance
Acidosis Vs Alkalosis
Respiratory Vs Metabolic Disturbances
Respiratory Disturbances
Metabolic Disturbances
Compensatory (Adaptive) Responses
Terminology
CLINICAL DISTURBANCES OF ACID-BASE BALANCE
Metabolic Acidosis
Metabolic Acidosis with an increased Anion Gap
Metabolic Alkalosis
Respiratory Acidosis
Respiratory Alkalosis
DISORDERS OF CALCIUM, PHOSPHORUS AND MAGNESIUM
Disorders of Calcium Homeostasis
Hypocalcemia
Hypercalcemia
Disorder of Phosphorous Homeostasis
Hypophosphatemia
Hyperphosphatemia
Disorder of Magnesium Homeostasis
Hypomagnesemia
Hypermagnesemia
5:
Hemostasis and Disorders of Surgical Bleeding
HEMOSTASIS
NORMAL HEMOSTASIS
Vascular Factors
Platelets Factors
Coagulation Factors
Fibrinolysis
HEMORRHAGE
Types of Hemorrhage
Clinical Features of Hemorrhage
Estimating the Hemorrhage
Treatment
Methods of Surgical Hemostasis
Bleeding Encountered at the Time of Surgery
MEDICAL HEMOSTASIS
INHERITED DISORDERS OF COAGULATION (Fig. 5.4)
Hemophilia
Clinical Features
von Willebrand's Disease
Laboratory Diagnosis
Management
Dosage calculation
ACQUIRED DISORDERS OF COAGULATION
Laboratory Diagnosis
Treatment
Vitamin K Deficiency
DISSEMINATED INTRAVASCULAR COAGULATION
Clinical Features
Laboratory Diagnosis
Treatment
PLATELET DISORDERS
Idiopathic Thrombocytopenic Purpura (ITP)
Laboratory Diagnosis
Treatment
Inherited Platelet Function Disorders
Clinical Features
Laboratory Diagnosis
Treatment
BLOOD COMPONENT THERAPY
Typing and Crossmatching
Whole Blood
Packed Red Cells (RBCs)
Platelets
Fresh Frozen Plasma (FFP)
Cryoprecipitate
Factors VIII and IX Concentrates
Albumin
Recycled Blood
Autologous Blood Transfusion
Patient selection
Plasma Substitutes
Dextrans
Complications of Blood Transfusions (Table 5.13)
Acute Hemolytic Reactions
Pyrexial Reactions
Allergic Reaction
Transfusion-related Acute Lung Injury (TRALI)
Transfusion-related Graft Vs Host Disease (TGVH)
Infection
Congestive Cardiac Failure
Air Embolism
Coagulation Defects
Massive Transfusion
6:
Metabolism and Nutrition in Surgical Patients
NORMAL METABOLISM
Glucose
Proteins:
Fats
METABOLISM DURING STARVATION
METABOLISM DURING SURGERY, TRAUMA AND SEPSIS
Catabolic Phase
Energy Balance
Lipid Metabolism
Carbohydrate Metabolism
Protein Metabolism
Early Anabolic Phase
Late Anabolic Phase
NUTRITION IN SURGICAL PATIENTS
Nutritional Assessment
Anthropometry
Biochemical Methods
Immune Competence
Clinical Assessment of Nutritional Status
Subjective Global Assessment
Nutritional Requirements
Energy Requirements
Protein Requirements
Vitamins and Essential Supplements
Routes of Nutritional Support
Enteral Nutrition
Parenteral Nutrition
Types of parenteral nutrition
Indications for parenteral nutrition
SECTION 2: WOUNDS AND INFECTIONS
7:
Wounds
HEALING OF WOUNDS: THE PHYSIOPATHOLOGY
Hemostasis and Inflammation
Coagulation
Chemotaxis
Proliferative Phase
Maturation Phase
Wound Contraction
Growth Factors and Wound Healing
Clinical Application and Effectiveness of Growth Factor Preparations in Wound Healing
TYPE OF WOUNDS
TYPES OF HEALING
Healing by First Intention
Healing by Secondary Intention
Healing in Open Wounds Without Skin Loss
FACTORS INFLUENCING WOUND HEALING
General Factors
Local Factors
CARE OF WOUNDS
CLOSURE OF WOUNDS
COMPLICATIONS OF HEALING
Wound Infection
Types of Wounds
Wound Dehiscence
Management
Wound Fibrosis
Scar
Scar Maturation
Hypertrophic Scar
Keloids
8:
Ulcers, Sinus and Fistula
ULCER
Course of an Ulcer
Examination of an Ulcer
Ulcer Documentation
Assessment of the Patient with an Ulcer
Nutritional Assessment and Management
Pain Assessment
Psychosocial Assessment
Tissue Load Management
Laboratory Diagnosis
Treatment of Ulcers
Care of an Ulcer
Debridement
Wound Cleansing
Dressings
Managing Bacterial Colonization and Infection
Common Types of Ulcers
Decubitus Ulcer
Treatment
Chronic Leg Ulcers
Venous Ulcer
Arterial Ulcers
Diabetic Foot Ulcers
SINUS
Types of Sinuses
Investigations
Treatment
FISTULA
Causes of Persistence of Fistula or Sinus
Treatment of a Fistula
9:
Surgical Infections
INFECTION
Sources of Infection
Endogenous Source
Exogenous Source
Transmission of Infection
Virulence
Causative Agents of Infections
Bacteria
Fungi
Viruses
Prevention of Infection in the Hospital
Surgical Wards
Hospital Audit of Infection
Operation Theaters
Disinfection
Heat Disinfection
Chemical Disinfection
Sterilization
Heat Methods
Ionizing Radiation
Ethylene Oxide
SURGERY AND INFECTION
Conduct of the Operative procedure
Care of Wounds
Control of Hospital Environment
Prophylactic Antibiotics
Surgical Wounds
Administration of Prophylactic Antibioties
Principles of Antibiotic Treatment
Organisms Commonly Responsible for Infections (Table 9.4)
Staphylococcus
Streptococcus
Enterobacteriaceae (Coliform bacilli)
Mycobacteria
Clostridia
Spirochaetes
Nonsporogenous Anaerobic Bacilli
Helicobacter (Camphylobacter) pylori
Antimicrobial Therapy
Antibiotics
Other β-lactam antibiotics
Antifungal Drugs
Antiviral Drugs
10:
Specific Infections
MYCOBACTERIAL DISEASES
Tuberculosis
Etiology
Transmission
Epidemiology
Incidence
Primary Infection
Reactivation Tuberculosis
Chemoprophylaxis
BCG Vaccine
Treatment
Treatment Regimens
Treatment Failures
Sputum Examination
Antitubercular Drugs
Other Drugs
Pulmonary Tuberculosis
Clinical Features
Pleural TB
Tuberculous Empyema
Investigations and Diagnosis
Treatment
Surgical Treatment
Extrapulmonary Tuberculosis
Peritoneal and Lymph Nodal Tuberculosis
Diagnosis
Gastrointestinal Tuberculosis
Common Presentations of Intestinal TB
Radiology
Medical Management
Surgical Management
Tuberculous Lymphadenitis
Diagnosis
Treatment
Genitourinary Tuberculosis
Investigations
Tubercular Meningitis
Diagnosis
Treatment
Miliary Tuberculosis
Diagnosis
Differential Diagnosis
Treatment
Tuberculosis of Bones and Joints
Other Mycobacterial Infection Resembling Tuberculosis
Pulmonary Disease
LEPROSY
COMMON BACTERIAL INFECTIONS
Erysipelas
Treatment
Acute Lymphangitis
Abscess
Causes of Abscess
Clinical Features
Treatment
Hidradenitis Suppurativa
Pseudomembranous Colitis
Gas Gangrene
Classification of Clostridial Infection
Clinical Features
Laboratory Diagnosis
Treatment
Prognosis
Tetanus
Clinical Features
Prophylaxis
Management in Generalized Tetanus
Complications
Prognosis
Actinomycosis
Treatment
Mycetoma
Treatment
Typhoid Fever
Investigations
Treatment
COMMON FUNGAL INFECTIONS
Blastomycosis
Histoplasmosis
Coccidioidomycosis
Cryptococcosis
Sporotrichosis
Aspergillosis
Candidiasis (Moniliasis)
Mucormycosis
Other Fungal Opportunists
Antifungal Drugs
Amphotericin B
Antifungal Azoles
COMMON VIRAL INFECTIONS
Respiratory Viral Diseases
Central Nervous System Viral Diseases
Rabies
Antirabies sera and vaccine
Prophylaxis
Prognosis
Herpesvirus Infections
Herpes Simplex
Herpes Zoster (Shingles)
Cytomegalovirus (CMV) Infection
Epstein-Barr (EB) Virus
Mumps
Smallpox
Opportunistic Infections
Bacterial Infections
Opportunistic Fungal Infections
Opportunistic Viral Infections
Opportunistic Parasitic Infections
Anaerobic Surgical Infections
Mixed Anaerobic Infections
Oral Cavity, Head and Neck
Lungs
Necrotizing Soft Tissue Infections (Table 10.6)
Intra-abdominal and Pelvic Infections
Collection of Specimens for Anaerobic Organisms
Treatment of Mixed Anaerobic Infections
Nosocomial Infections
Infection of a Surgical Wound
Urinary Tract Infection
Respiratory Infection
Intravenous Catheter Related Sepsis
SEXUALLY TRANSMITTED DISEASES
Gonorrhea
Clinical Features
Diagnosis
Treatment
Nongonoccal Urethritis and Genital Infection
Clinical Features
Diagnosis
Treatment
Trichomoniasis
Clinical Features
Diagnosis
Treatment
Syphilis
Clinical Features
Diagnosis
Treatment
Chancroid
Clinical Features
Diagnosis
Treatment
Donovanosis (Synonym: Granuloma Inguinale)
Clinical Features
Diagnosis
Treatment
Lymphogranuloma Venereum
Clinical Features
Diagnosis
Treatment
Genital Herpes
Clinical Features
Laboratory Diagnosis
Treatment
Genital Warts (Syn. Condyloma Accuminata)
Clinical Features
Diagnosis
Treatment
HIV infection and AIDS
Clinical Features
Laboratory Diagnosis
Treatment
Syndromic Approach to the Management of Sexually Transmitted Diseases
11:
Sepsis and Multiple Organ Dysfunction Syndrome
MULTIPLE ORGAN DYSFUNCTION SYNDROME
Setting in Which MODS Occurs
Microbiology of Sepsis
Pathophysiology of Sepsis
Microvascular Alterations
Cardiorespiratory Alterations
Renal Alterations
CNS Alterations
Gastrointestinal Alteration
Clinical Features
Pathogenesis of MODS
Metabolism
Management
Prevention of MODS
Early and Aggressive Resuscitation during Shock
Monitoring
Nutrition
Control of Sepsis
12:
Surgeons and Communicable Diseases
RISKS
Hepatitis B
Clinical Course
Complications
Hepatitis C
Complications
HIV Infection
Transmission of HIV
Acquired Immunodeficiency Syndrome (AIDS)
Infectious Complications of HIV
Opportunistic Tumors
Screening for HIV
Who Should be Tested?
Indication for Testing
Risks to Health Care Workers
Reduction of Risk to Health Care Workers
Management Following Exposure
Postexposure Prophylaxis
SECTION 3: PREPARATION FOR SURGERY
13:
Principles of Anesthesia
THE HISTORY OF ANESTHESIA
Overview of Anesthetic Practice
Anesthetic Management
Choice of Anesthesia: General or Regional?
BASIC ANESTHETIC PHARMACOLOGY
Intravenous Nonopiate Anesthetics
Barbiturates: Thiopentone
Ketamine
Propofol
Volatile Anesthetic Agents
Nitrous Oxide (N2O)
Halothane
Isoflurane
Desflurane
Sevoflurane
Ether
ADJUNCTS IN ANESTHESIA—NARCOTIC AND MUSCLE RELAXANTS
Classification of Opioids
Morphine
Pethidine
Fentanyl
Tramadol
Buprenorphine
Pentazocine
PHYSIOLOGY OF THE NEUROMUSCULAR JUNCTION
Differentiation Between a Depolarizing and a Non Depolarizing Block (Table 13.4)
Reversal of Block
Depolarising Relaxants
Nondepolarizing Relaxants
Tubocurarine
Atracurium
Pancuronium
Vecuronium
Rocuronium
THEORIES OF ANESTHESIA
Agent Specific Theory
Unitary Hypothesis
Critical Volume Hypothesis
ANESTHESIA EQUIPMENT
Laryngeal Mask Airway
Local Anesthetic Agents
Structure-Activity Relationships
Local Absorption of Anesthetic Agents
Amides
Effects on Organ Systems and Toxicity
Cardiovascular
Cerebral
SPINAL, EPIDURAL AND CAUDAL BLOCK
Spinal Anesthesia
Indications and Contraindications
Patient Preparation
Technique
Effects of Spinal and Epidural Blockade
Somatic Block
Visceral Blockade
Factors Affecting the Height of Spinal Block
Complications of Spinal Anesthesia
Epidural Anesthesia
Combined Spinal-epidural Anesthesia (Fig. 13.21)
GIVING A ROUTINE GENERAL ANESTHETIC
POSTANESTHESIA CARE AND CARE OF THE UNCONSCIOUS PATIENT
14:
Preoperative Preparation and Postoperative Care
PREOPERATIVE PREPARATION
Assessment of the Operative-risk
Risks of Primary Disease
Risks of Concomitant Diseases
Evaluation of the Patient
Cardiovascular System and Bleeding Diathesis
Respiratory System
Renal System
Gastrointestinal Tract
Fluid Deficits
Fasting
Anemia
Metabolic Disorders
Diabetes Mellitus
Thyroid Disorders
Liver Disorders
Extremes of Age
Preoperative Investigations
Routine Investigations
Special Investigations
Preparation Before Surgery
Consent
Clinical Records
Preoperative Fasting
Bowel Preparation
Prevention of Infection
Preoperative Medications
Deep Vein Thrombosis (DVT)
Prevention of DVT
Non-specific Measures
Specific Measures
Blood Grouping and Cross Matching
POSTOPERATIVE MANAGEMENT
Nursing Care
Immediate Postoperative Care
Fluid Management in the Postoperative Period
Postoperative Pain Management
Nasogastric Tube
Drains
Daily Postoperative Assessment
Physiotherapy and Mobilization
Antibiotics and Other Medications
Postoperative Investigations
Oral Feeding and Nutrition
Nutritional Support
Care of the Wound
Suture Removal
Communication with the Patient
Fever in the Postoperative Period
DISCHARGE
15:
Surgical Intensive Care
DEVELOPMENT OF INTENSIVE CARE UNIT
MECHANISM OF ORGAN FAILURE
MONITORING IN A CRITICALLY ILL PATIENT
Arterial Blood Pressure
Continuous Electrocardiography
Central Venous Pressure
Indications of Use of CVP Monitoring
Choice of Route for CVP
Pulmonary Artery Pressure Monitoring
Respiratory Rate (RR)
Arterial O2 Saturation
Arterial Blood Gases and Acid-base Balance
Temperature
Urine Output
Laboratory Parameters
SUPPORTIVE TREATMENT IN CRITICALLY ILL PATIENTS
Cardiovascular Support
Assessment of Volume Status
Fluid Administration
Hypoxia
Arrhythmias
Ionotropic Agents in Cardiac Support
Dopamine
Dobutamine
Respiratory Support
Respiratory Failure
Airway and Endotracheal Intubation
Ventilation
Renal Support
Management
Volume Status
Nutritional Support
Use of Sedative, Analgesic and Neuromuscular Blocking Agents in the ICU
Sedation in the ICU
Pain Management in the ICU
Benefits of Adequate Pain Control
Methods of Analgesic Delivery
Neuromuscular Blocking Agents (NMBAs)
Patient Systems for Quality Management in the ICU
16:
Complications of Surgery
AVOIDANCE OF COMPLICATIONS
Respiratory System
Atelectasis
Pneumonitis
Aspiration
Fat Embolism Syndrome
Respiratory Failure
Renal System
Acute Renal Failure
Investigations and Diagnosis
Management
Postoperative Retention of Urine
Gastrointestinal System
Acute Erosive Gastritis
Ileus
Postoperative Fever
Clinical Features
Cardiac System
Myocardial Infarction
Cardiac Arrest and Resuscitation
Resuscitation
Postoperative Psychosis
Management
SECTION 4: TRAUMA AND BURNS
17:
Trauma
EXTENT OF PROBLEM
PRIMARY PREVENTION
Role of Planners
Role of Administrators
Role of Engineers and Vehicle Designers
Role of Educationists
Responsibility of Road Users
Role of Traffic Planners
SECONDARY PREVENTION
Prehospital Care
DISASTER MANAGEMENT: HOW TO PLAN AND EXECUTE?
Planning
Hospital Planning
Triage
Preparation
Prehospital phase
In-hospital phase
TRAUMA RESUSCITATION
Primary Survey
A. Airway and Cervical Spine
B. Breathing
C. Circulation
D. Disability
E. Expose and Environment
Adjuncts to Primary Survey
Secondary Survey
History
Transfer to Definitive Care
DEFINITIVE TREATMENT OF SPECIFIC INJURIES
Chest Injuries
Cardiac Injuries
Aorta
Esophagus
Abdominal Injuries (Table 17.2)
Damage Control Surgery
Spleen
Liver
Gallbladder
Stomach
Small Bowel
Mesentery
Duodenum and Pancreas
Colon
Rectum and Anal Canal
Kidney and Ureter
Bladder
Head Injury
Neck
Vascular Injuries
Crush Syndrome (Traumatic Rhabdomyolysis)
Vertebral and Spinal Cord Trauma
Absence of Neurological Deficit Does Not Rule Out Spinal Injury
Spinal Shock
Pelvic Fractures and Perineal Injury
Perineal Injuries
GUNSHOT AND BLAST INJURIES
Ballistics
Properties of Missile
Mechanism of Missile Injury
High Energy Transfer
Mechanism of Blast Injuries
Injuries Due to Primary, and Secondary Missiles
Penetrating Missile Injury
Principles of Management
Nuclear Accidents
Medical Effects of Radiation
Units of Measurement of Radiation
Clinical Syndromes
Treatment
External and Internal Contamination with Radioactive Material
Prophylaxis
Evacuation
Shelter
Practical Points in Management of Violent Trauma
18:
Thermal, Chemical and Electrical Injuries
BURN
Types of Thermal Injury
STRUCTURE OF THE SKIN
Pathophysiology of Burns
Local Effects
Regional Effects
Systemic Effects
Evaluation of the Burn
Assessment of a Patient with Burns
Management of the Patient
First Aid
Emergency Management in the Hospital
Fluid management
Resuscitation in Children
Burn Wound Management
Local Care of the Burn Wound
Excision of the burn wound
Complications of Burns
Infections
Systemic infections
Gastrointestinal Complications
Late Complications
Scars and Contractures
INHALATIONAL INJURY
Supportive Care
Control of Infection
Nutritional Support
COLD INJURY
Frostbite
Pathophysiology
Clinical Features
Predisposing Factors
Treatment
Management of the Specific Injury
ELECTRICAL INJURIES
High Voltage Injuries
Low Voltage Injuries
Prevention of Electrical Injuries
Treatment
Complications
CHEMICAL INJURIES
Pathophysiology
Management
Hydrotherapy
SECTION 5: SPECIALTIES THAT ASSIST A SURGEON
19:
Radiology for the Surgeon
WHAT ARE ‘X-RAYS’?
Plain Radiographs
Fluoroscopy
Contrast Agents
Ultrasonography (US)
B-mode or Gray Scale Imaging
Real-time scanning
Color Doppler Imaging
Advantages of Ultrasonography
Computerized Tomography (CT scan)
Helical (Spiral) CT
Magnetic Resonance Imaging
Advantages of MRI
Angiography
Digital Subtraction Angiography (DSA)
IMAGING APPROACH TO ORGAN SYSTEMS
Chest Imaging
Plain Radiographs
Fluoroscopy
Bronchography
Ultrasound
Computerized Tomography
Magnetic Resonance Imaging
Abdominal Imaging (Gastrointestinal Tract)
Plain Radiograph of the Abdomen
Salivary Glands
Esophagus
Stomach and Duodenum
Small Bowel
Large Bowel
Hepato-Biliary System and Pancreas
Urinary Tract and Adrenals
Musculoskeletal System
Imaging of Trauma
Imaging of Infection
Imaging for Tumors
Foreign Body Evaluation
Vascular System
Breast Imaging
Interventional Radiology
Vascular Procedures
Non-Vascular Procedures
20:
Nuclear Medicine
INVESTIGATIVE TECHNIQUES
Advantages of Nuclear Imaging
SCINTIGRAPHY (IMAGING) OF ORGANS
Scintigraphy
Dynamic Function Studies
Dilution Studies
Thyroid Function Studies
Renal Function Studies
Liver Function Studies
Hematology
Blood Flow
Absorption Studies
Therapeutic Applications of Radioisotopes
Radioisotope Therapy
Radioimmunotherapy
Therapeutic Uses
POSITRON EMISSION TOMOGRAPHY
21:
Pathology for the Surgeon
CYTOLOGY
BIOPSY
Types of Biopsy
Taking a Good Biopsy
Transport of Specimens
Fixative
Processing of the Specimen
Section Cutting and Staining
Reporting of Histopathologic Diagnosis
FROZEN SECTION
SPECIAL TECHNIQUES
Special Stains
Immunohistochemistry
Molecular Pathology
Filter Hybridization
In Situ Hybridization
Polymerase Chain Reaction (PCR)
Enzyme Histochemistry
Electron Microscopy
Computer-assisted Morphometry and Image Analysis
Flow Cytometry
BIOPSY OF SPECIFIC TISSUES
22:
Microbiology for the Surgeon
HOSPITAL ENVIRONMENT AND INFECTION
Protection Against Infection
Quantitation of Microorganisms
Infections in Immunocompromised patients
LABORATORY TECHNIQUES (For Diagnosis of Surgical Infections)
Transportation of Specimen
Specimen Collection
Collection and Transportation of Surgical Infection Specimens
Deep wounds or abscesses:
Laboratory Processing
Direct Microscopic Examination
Microbiological Cultures
Blood Culture
Automated Methods for Blood Culture
Fungemia
Tissue Culture
Immunodiagnosis
Agglutination
Precipitation
Complement Fixation Test (CFT)
Indirect Fluorescent Antibody Test (IFAT)
Radioimmunoassay (RIA)
Enzyme Linked Immunosorbent Assays (ELISA)
Gas-liquid Chromatography
Molecular Diagnostics
No Target Amplification Technique
Amplification Techniques
MICROBIOLOGY IN CLINICAL PRACTICE
Surgical Wounds
Wound Types
Microbiological Aspects of Wound Infection
Microbiological Analysis
Necrotizing Soft Tissue Infections
Simple Superficial Infections
Fascial Level Infections
Bacterial Myonecrosis
Septicemia
Infections in Prosthetic Devices
Infections Associated with Implants
Microbiological Aspects of Graft Infection
Intravenous and Central Catheter Infection
23:
Principles of Oncology
INTRODUCTION
CANCER SCENARIO: INDIA AND GLOBAL
MAGNITUDE OF CANCER PROBLEM IN INDIA
Carcinogenesis
Angiogenesis
Growth of Tumors
Carcinogens
Physical Carcinogens
Chemical Carcinogens
Biological Agents
Immunity and Cancer
Genetics and Cancer
Proto-oncogenes
Oncogenes
Tumor Suppressor Genes
Tumor Markers
MANAGEMENT OF CANCER PATIENTS
Complete History and Physical Examination
Investigation
Urine Examination
Radiology
Endoscopy
Tissue Diagnosis
Staging of Cancer
TNM System of Staging
Pathological Staging
Screening for Cancer
TREATMENT MODALITIES
Surgical Oncology
Diagnosis and Staging of Cancer
Presurgical Assessment
Definitive Operations in Cancer
Local Resections
Radical Resections with en bloc Excision of Draining Lymph Nodes
Surgery for Debulking
Palliative and Reconstructive Surgery
Surgery for Metastatic Disease
Salvage Surgery
Preventive Surgery
PRINCIPLES OF RADIOTHERAPY
PHYSICS OF RADIOTHERAPY AND EQUIPMENTS
Physics of Radiation Therapy
Radiation Dose
RADIOTHERAPY EQUIPMENT
BASICS OF RADIATION BIOLOGY
Target Theory and Survival Curves
Dose Response Curves and Therapeutic Ratio
Practices of Radiotherapy: Curvative, Preoperative, Postoperative and Palliative
Curative Radiotherapy
Combination of Irradiation and Surgery
Preoperative Radiation
Postoperative Radiotherapy
Palliative Radiotherapy
Bone Metastasis
Advanced Lung Cancer
Esophageal Obstruction
Hemorrhage
Raised Intracranial Pressure
Spinal Cord Compression
CHEMOTHERAPY—PRINCIPLES AND PRACTICE
Introduction
Adjuvant Chemotherapy
Neoadjuvant Chemotherapy
Primary Chemotherapy
Concomitant Chemoradiotherapy
Salvage or Palliative Chemotherapy
PRINCIPLES OF CHEMOTHERAPY
Classification of Anticancer Drugs
Non Phase-Dependent Drugs (Non cell cycle Dependent)
Phase-Dependent (Cell cycle Specific) Drugs
Combination Chemotherapy
Response Assessment
Toxicity
Acute Toxicity
Skin Toxicity
Long-term Toxicity
Carcinogenesis
Hormones in the Treatment of Cancer
Immunotherapy
Passive Immunotherapy
Active (Specific) Immunotherapy
Nonspecific Immunotherapy
Adoptive Immunotherapy
SECTION 6: IMMUNOLOGY AND TRANSPLANTATION
24:
Immunology
INTRODUCTION
HISTORY OF IMMUNOLOGY
INTRODUCTION TO IMMUNOLOGY
IMMUNITY
INNATE IMMUNITY
Outer Surfaces of the Body
Physiochemical Barriers
Other Physiological Barriers
Internal Tissues of the Body
Molecular Elements of Innate Immunity
Cellular Elements of Innate Immunity
Major Histocompatibility Complex
ACQUIRED IMMUNITY
Molecular Elements of Acquired Immunity
Antigen
Cellular Elements of Acquired Immunity
Lymphocytes
Lymphocytes Recognize Antigen to Give Rise to Immune Response
Two Major Phenotypes of Lymphocytes
Cell Surface Molecules and Activated Products
Cell Types with Cytotoxic Activity
Antibody Mediated Immunity
Cell-mediated Immunity
INNATE AND ACQUIRED IMMUNITY MAY ACT SINGLY, IN COMBINATION OR IN CONTINUUM
IN SUMMARY
STRATEGY OF THE IMMUNE SYSTEM
Cells of the Immune System
Molecules of the Immune System
Cells that Process and Present Antigen in Association with MHC Molecules
Recognition of Antigen and Activation of Anti-nonself Lymphocytes
Regulation of the Immune Response
Attributes of Earlier Concepts and Newer Molecular Techniques in Immunology
IMMUNE RESPONSE IN MICROBIAL IMMUNITY AND DISEASE OF IMMUNITY
IMMUNE RESPONSE TO AN ANTIGENIC STIMULUS IS A MULTISTEP PHENOMENON
IMMUNITY MAY BE EXPRESSED IN THREE FORMS: APPROPRIATE, IMPAIRED AND INAPPROPRIATE
Appropriate Immunity
Immunity to Infection
Immunity to Bacterial and Viral Infections
Impaired Immunity
Immunodeficiency
Therapies in Immunodeficiency States
INTRAVENOUS IMMUNOGLOBULIN (IVIg) PREPARATIONS
Inappropriate Immunity
Hypersensitivity
Autoimmunity
Transplantation Immunity
Transplantation in Clinical Practice
Malignancies
IMMUNOLOGICAL INVESTIGATIONS RELEVANT TO THE MANAGEMENT OF THE PATIENT
IMMUNOLOGY AT A GLANCE
Landmark in Immunology and Turning-point in History
25:
Transplantation
INTRODUCTION
TYPES OF GRAFTS
Rejection
Major Histocompatibility Antigen
Lymphocytes
Cross-match
Immunology of Transplantation
Organ Retrieval and Organ Preservation
Organ Preservation
Immunosuppression
Immunosuppression Agents
Complications of Immunosuppression
TRANSPLANTATION OF INDIVIDUAL ORGANS
Kidney
The Donor
Transplant or Dialysis?
Heart
Indications for Cardiac Transplant
Evaluation of the Patient Before Transplantation
Donor Criteria for Heart Transplant and Guidelines for Recipient Matching
Donor Cardiectomy
Recipient Operation
Results of Cardiac Transplant
Lung
Transplant Operation
Liver
Donor Selection
Cadaver Donor Procurement Procedure
Recipient Operation
Veno-venous Bypass
Cadaver Donor Transplant
Results
Pancreas
Evaluating Candidates for Pancreas Transplantation
Transplant Operation
Islet Cells
Small Bowel
26:
Death and Organ Donation
INTRODUCTION
ORGAN DONATION AND RETRIEVAL
Renal Graft Donor: Live-related and Cadaveric
Living Renal Donor
Technique of Live Donor Operation
Cadaveric Renal Donor (Table 26.1)
Technique of Donor Operation
Removal of Kidney Alone
Multiorgan Retrieval
SECTION 7: SKIN, HAND AND FOOT AND BREAST
27:
Skin
FUNCTIONAL ANATOMY OF THE SKIN
SURGICAL CONDITIONS OF THE SKIN
Principles of Surgical Management of Cutaneous Lesions
Infections and Inflammations
Bacterial Infections
Boil or Furuncle
Carbuncle
Cellulitis
Hidradenitis Suppurativa
Hamartomas, Hemangiomas and Lymphangiomas
Hamartomas of Epidermal Structures
Hamartomas of Dermal Structures
Vascular Anomalies
Hemangiomas
Cherry Angiomas (Senile Angiomas, Cambell de Morgan Spots)
Nevus Flammeus
Pyogenic Granuloma
Lymphangioma
Cysts
Epidermal Cysts (Sebaceous Cyst) (Fig. 27.16)
Trichilemmal Cysts (Pilar Cysts)
Dermoid Cysts
Milia
Benign Epidermal Tumors
Skin Tag (Fibroepithelial papilloma, Achrochordon)
Tumors of Skin Appendages
Trichofolliculoma (Hair Follicle Nevus)
Trichoepithelioma
Pilomatricoma
Sebaceous Adenoma
Cylindroma
Syringoma
Dermal Tumors
Lipoma
Neurofibroma
Dermatofibroma (Fibrous Histiocytoma, Sclerosing Hemangioma)
Keratoacanthoma
Benign Melanocytic Lesions
Clinical Features
Spitz Nevus (Benign Juvenile Melanoma)
Dysplastic Nevus or Atypical Mole
Clinical Features
Histopathology
Management
Predisposing Factors for Malignant Skin Tumors and Premalignant Conditions
Actinic (solar) Damage
Actinic Keratosis
Other Carcinogenic Factors
Basal Cell Carcinoma
Treatment
Squamous Cell Carcinoma
Treatment
Malignant Melanoma
Incidence
Aetiology
Classification of Melanoma
Prognostic Factors in Melanoma
Clinical Features
Staging
Treatment
28:
Plastic Surgery
GENERAL PRINCIPLES
Skin Incision
Wound Closure
Dog-Ear
Postoperative Care of Wound
Dressing
Suture Removal
Z-Plasty
Single and Multiple Z Plasty
SKIN GRAFTING
Split Thickness Skin Graft (Thirsch Graft, SSG)
Full Thickness Skin Graft (Wolfe Graft)
Stamp Graft
Composite Graft
Donor Area
Survival of Graft
Factors affecting Graft Survival
FLAPS
Free Flap (Microvascular Flap)
Indication for Free Flap Reconstruction
Survival of Flaps
TISSUE EXPANSION
SUCTION LIPECTOMY
IMPLANT AND BIOMATERIALS
29:
Hand and Foot
HAND
Positions of the Hand
Anatomy
Skin
Flexor Lines (Skin–creases)
Superficial Fascia
Deep Fascia
Carpal Bones
Scaphoid
Innervation of Hand
Blood Supply of Hand
Fractures of Hand
Crush Injuries of the Hand
Assessment of Hand Injuries
Treatment
Infections of Hand
Conditions Predisposing to Infections
History and Examination
Treatment
Nailbed Infections
Acute Paronychia
Chronic Paronychia
Felon
Bite Wounds of Hand
Deep Space Infections of Palm
Web Space Infection
Mid-palmar Space Infection
Thenar Space Infections
Infection of the Tendon Sheaths
Flexor Tenosynovitis
Principle of Treatment of Hand Infections
Complications of Hand Infections
Common Conditions of Hand
Trigger Finger/Thumb
Carpal Tunnel Syndrome
Causes
Treatment
Complications
Compound Palmar Ganglion
DeQuervain's Stenosing Tenosynovitis
Dupuytren's Contracture
Ganglion
Giant Cell Tumor of Tendon Sheath
Congenital Abnormalities
Syndactyly
Polydactyly
Tumors of Hand
Enchondroma
Hand Splinting
FOOT
Movements of the Foot and Ankle
Joints About the Foot and Ankle
Accessory Navicular Bone
Clinical Features
Radiology
Treatment
Club Foot (Congenital Talipes Equino Varus)
Flat Foot (Pes Planus)
Clinical Features
Treatment
Metatarsalgia
Etiology
Clinical Features
Treatment
Kohler's Disease
Clinical Features
Radiology
Treatment
Plantar Fasciitis
Clinical Features
Treatment
Hallux Rigidus
Clinical Features
Radiographs
Treatment
Hallux Valgus
Clinical Features
Radiology
Treatment
Rheumatoid Foot
Radiology
Treatment
Tuberculosis of the Foot and Ankle
Clinical Features
Radiology
Treatment
Diabetic Foot
Treatment
Osteomyelitis
Pathology
Clinical Features
Treatment
Athlete's Foot
Clinical Features
Treatment
Prevention
Fungal Nails
Clinical Features
Ingrowing Toe Nails (Onchocryptosis)
Causes
Clinical Features
Treatment
Ankle Sprain
Clinical Features
Radiology
Management
Bone Tumors (Benign)
Osteochondroma
Enchondroma
Chondroblastoma
Chondromyxoid Fibroma
Malignant Bone Tumors
Ewing's Sarcoma
Chondrosarcoma
Amputations of Foot and Ankle
30:
Soft Tissue Tumors
INTRODUCTION
EPIDEMIOLOGY
ETIOLOGY
PATHOGENESIS
CLINICAL PRESENTATION AND DIAGNOSIS
Radiology
Tissue Diagnosis
Types of Biopsy
CLASSIFICATION OF SOFT TISSUE TUMORS
GRADING OF SOFT TISSUE SARCOMA
PROGNOSTIC FACTORS
Clinicopathological Prognostic Factors
Molecular Prognostic Factors
NATURAL HISTORY AND BIOLOGIC BEHAVIOR OF SOFT TISSUE TUMORS
STAGING OF SOFT TISSUE SARCOMA
TREATMENT OF SOFT TISSUE TUMORS
Principles of Surgical Resection for Soft Tissue Sarcoma
Types of Surgical Resection
Limited Resections
Wide Local Resections
Compartment Resections
Amputations
Surgical Management of Retroperitoneal Soft Tissue Sarcomas
Role of Radiotherapy in the Management of Soft Tissue Sarcoma
Role of Chemotherapy in the Management of Soft Tissue Sarcoma
Neoadjuvant Chemotherapy, Isolated Limb Perfusion and Hyperthermia for Soft Tissue
Treatment of Metastatic Soft Tissue Sarcoma
31:
Breast
EMBRYOLOGY AND ANATOMY
Structure
Blood Supply
Lymphatic Drainage
CONGENITAL ANOMALIES
Aberrations of Normal Development and Involution (ANDI, Benign breast disease)
Pathology
Clinical Presentation
Investigations and Diagnosis
Treatment
Galactocele
Fat Necrosis
Breast Infection
Lactational Abscess (Breast Abscess)
Stages of Infection
Clinical Features
Treatment
Nonlactational Abscess
Chronic Abscess
Tuberculosis of the Breast
NIPPLE DISCHARGE
Color of Discharge
Management
Mondor's Disease
TUMORS OF THE BREAST
Benign Tumors
Fibroadenoma
Pathology
Treatment
Giant Fibroadenoma
Cystosarcoma Phylloides
Pathology
Clinical Features
Treatment
Intraductal Papilloma
Carcinoma of the Breast
Risk Factors for Development of Breast Cancer
Pathology
Paget's Disease of the Nipple
Ductal Carcinoma
Lobular Carcinoma
Rarer Tumors
Spread of Breast Cancer
Clinical Staging
TNM System of Staging
Clinical Features
Investigations and Diagnosis
Mammography
Fine Needle Aspiration Cytology (FNAC)
Core Biopsy
Open Surgical Biopsy
Ultrasonography
Frozen Section
Evaluation for Distant Disease
Hormone Receptors (ER and PR)
Treatment of Breast Cancer
Surgery
Early Breast Cancer
Locally Advanced Breast Cancer (LABC)
Metastatic Breast Cancer
Recurrent Breast Cancer
Operation for Breast Cancer
Adjuvant Therapy for Breast Cancer
Pregnancy and Breast Cancer
Prognosis and Prognostic Factors
Breast Reconstruction
SECTION 8: HEAD AND NECK
32:
Face and Salivary Gland
FACE
Cleft Lip and Palate
Classification
Treatment
Pierre-Robin Syndrome
Treatment
Preauricular Sinus
Infections of the Face
Treatment
Injuries of the Face and Neck
Clinical Evaluation of a Patient
Management
Fractures of the Facial Skeleton
Treatment
Fractures of the Mandible
Treatment
Treatment
Benign Tumors of the Face
THE SALIVARY GLANDS
Anatomy
SALIVARY GLAND TUMORS
Benign Tumors
Malignant Tumors
Clinical Examination
Diagnosis
Staging
Management
Complications of Parotidectomy
INFLAMMATORY DISORDERS (TABLE 32.3)
Acute Sialadenitis
Clinical Features
Management
Chronic Sialadenitis
Treatment
Sialolithiasis
Clinical Features
Treatment
Mikulicz Disease
Clinical Features
Treatment
33:
Teeth and Jaw
DENTAL ANATOMY, HISTOLOGY AND PHYSIOLOGY
Structure of Teeth
Enamel
Dentin
Cementum
Pulp
Periodontium
DISEASES OF TEETH
Dental Caries
Classification of Caries
Treatment of Dental Caries
Impacted Wisdom Tooth
Infections of Oral Soft Tissues and Bone
Dental Abscess
Fascial Space Infections
Osteomyelitis of the Jaws
Tumors of the Alveolus (Epulides)
Tumors and Cysts of the Jaw
Classification of Jaw Cysts
Diagnosis of Jaw Cysts
Treatment
Odontogenic Tumors
Epithelial Odontogenic Tumours
Mesodermal Odontogenic Tumors
Malignant Odontogenic Tumours
Fibro-osseous Disease and Benign Tumors of Bone
TMJ Ankylosis
Fractures of Jaw
34:
Neck
ANATOMY
Muscles of the Neck (Fig. 34.1)
Superficial Muscles
Deep Muscles
Fasciae of the Neck (Fig. 34.1)
Superficial Fascia
Deep Fascia
Triangles of the Neck
Anterior Triangle
Posterior Triangle
Lymph Nodes of the Neck
EMBRYOLOGY OF THE NECK IN RELATION TO DEVELOPMENTAL PROBLEMS
Branchial Cysts
Branchial Sinus and Fistula
Cystic Hygroma
Thyroglossal Tract and Its Remnants
Thyroglossal Cysts
Thyroglossal Fistula and Sinus
Sternomastoid Tumor
Infection of Spaces in the Neck
Cervical Lymphadenopathy
Tuberculous Lymphadenitis
Diagnosis
Atypical Mycobacterial Infections
CERVICAL LYMPHADENOPATHY AND MALIGNANCY
Lymphomas
Leukemias
Metastatic Lymphadenopathy
Assessment in Patients with Suspected Metastatic Cervical Lymphadenopathy
Staging of Cervical Lymph Node Metastases
NECK DISSECTION
Types of Neck Dissection
Radical Neck Dissection
Modified Neck Dissections
Selective Neck Dissections
Central (Anterior) Neck Dissection
Extended Neck Dissection
Surgical Technique of Radical Neck Dissection
CAROTID BODY TUMORS
35:
Oral Cavity and Tongue
ANATOMY
INFLAMMATORY CONDITIONS
NEOPLASMS OF THE ORAL CAVITY AND TONGUE
Etiological Factors
Premalignant Lesions of the Oral Cavity
Leukoplakia
Submucous Fibrosis
Plummer-Vinson (or Patterson-Kelly) Syndrome
Solar Keratosis
PATHOLOGY OF ORAL CANCERS
Types of Cancer (Gross Appearance)
Microscopic Appearance
Lymphatic Spread
TNM Staging
Prognostic Factors
Clinical Presentations
Investigations
Management
Withdrawal of Contributory Causes
Early Detection
Definitive Treatment
Extent of the disease
Radiotherapy
Surgery
Reconstruction
Chemotherapy
Cancers of Specific Sites
Lip
Buccal Mucosa
Hard Palate
Reconstruction
Floor of Mouth
Alveolus
Tongue
Cancer of the Tongue
Pathology
Clinical Features
Investigation
Treatment
36:
Pharynx
ANATOMY
DISEASES OF PHARYNGEAL LYMPHOID TISSUE
Palatine Tonsil
Acute Tonsillitis
Treatment
Hypertrophy of the Adenoids and Tonsils
Angiofibroma
Treatment
PHARYNX
Pharyngeal Pouch
Etiology
Clinical Feature
Management
Malignant Diseases of the Pharynx
Cancer of the Nasopharynx
Cancer of the Oropharynx
Cancers of the Hypopharynx
SECTION 9: ENDOCRINE SURGERY
37:
Thyroid
EMBRYOLOGY
ANATOMY
Arterial Supply of the Thyroid and the Parathyroid
Venous Drainage
Lymphatic Drainage of the Thyroid Gland
Superior and Medial Drainage
Inferior and Medial Drainage
Lateral Drainage
Recurrent Laryngeal Nerve
Superior Laryngeal Nerve
Microscopic Anatomy
PHYSIOLOGY OF THE THYROID HORMONES
Iodine Metabolism
Synthesis of Thyroid Hormone
Storage and release of T3 and T4
Transport and Metabolism of Thyroid Hormones
Regulation of Thyroid Hormone Synthesis and Release
THYROID FUNCTION TESTS
Dynamic Tests of Thyroid Function
Radioactive Iodine Uptake
T3 or T4 Suppression Test
Tests of Thyroid Dysfunction
Tests for Suspected Thyroid Malignancy
Thyroid Scan
Ultrasound of Neck
CT and MRI
Serum Calcitonin
Serum Thyroglobulin
EMBRYOLOGICAL ABNORMALITIES
Thyroglossal Tract and its Remnants
Lingual Thyroid
Accessory and Ectopic Thyroids
PATHOLOGICAL STATES OF THYROID ENLARGEMENT
Endemic Goiter
Familial Goiter
Sporadic Goiter
Endemic Multinodular Goiter
Pathogenesis
Pathology
Clinical Features
Investigations
Treatment
Complications of Multinodular Goiter
THYROTOXICOSIS/HYPERTHYROIDISM
Graves' Disease
Pathogenesis
Ophthalmopathy
Pathology
Clinical Features
Toxic Multinodular Goiter (Plummer's Disease)
Toxic Adenoma
Other Varieties of Thyrotoxicosis
Investigations
Thyroid Function Test
Thyroid Antibodies
Radioactive Iodine Uptake (RAIU) and Thyroid Scan
Treatment of Hyperthyroidism
Medical Therapy
Radioiodine Therapy
Surgical Therapy
Complications of surgery
Treatment of Ophthalmopathy
Thyrotoxic Crisis (or Thyroid Storm)
Treatment
Solitary Thyroid Nodule
Clinical Features
Evaluation of Solitary Thyroid Nodule
Management of Solitary Thyroid Nodule
TUMORS OF THE THYROID
Benign Tumors
Thyroid Cancer
Molecular Biology of Thyroid Cancer
Papillary Carcinoma
Pathology
Clinical Features
Prognosis
Investigation
Treatment
Follicular Carcinoma
Pathology
Clinical Features
Investigations
Treatment
Prognosis
Hurthle Cell Carcinoma
Medullary Thyroid Carcinoma
Pathology
Clinical Features
Investigations
Treatment
Anaplastic Thyroid Carcinoma
Pathology
Clinical Features
Investigations
Treatment
Pre-existing Thyroid Disease and Thyroid Cancer
Hypothyroidism
Clinical Features
Investigations
Treatment
THYROIDITIS
Hashimoto's Thyroiditis
Pathology
Clinical Features
Treatment
Subacute Thyroiditis (De Quervain's Thyroiditis)
Riedel's Thyroiditis
Surgery of the Thyroid
Types of Operations on the Thyroid Gland
Postoperative Complications
38:
Parathyroids
ANATOMY
PHYSIOLOGY
CALCITONIN
HYPERPARATHYROIDISM
Etiology and Pathogenesis
Classification of Hyperparathyroidism
Pathology
Parathyroid Adenoma
Parathyroid Hyperplasia
Parathyroid Carcinoma
Ectopic Parathyroid Glands
Multiple Endocrine Neoplasia (MEN) Syndrome
Clinical Features of Hyperparathyroidism
Clinical Examination
Laboratory Findings
Radiological Features
Others
Preoperative Localization
Intraoperative Localization
Treatment
Surgery
Surgery of Primary Hyperparathyroidism
Complications of Surgery
Observation and Monitoring
Indications
Indications for Surgery in Patients with Asymptomatic Hyperparathyroidism
Medical Treatment of Primary Hyperparathyroidism
Reversal of Symptoms
Recurrence after Surgery
Acute Hyperparathyroidism
Treatment
HYPOPARATHYROIDISM
Clinical Features
Treatment of Hypocalcemia
39:
Adrenal Gland
HISTORY
EMBRYOLOGY
ANATOMY
ADRENAL CORTEX
Physiology
Catecholamine Synthesis
Congenital Adrenal Hyperplasia
Hyperaldosteronism
Primary Hyperaldosteronism (Conn's Syndrome)
Secondary Hyperaldosteronism
Neuroblastoma
Cushing's Syndrome
Clinical Features (Table 39.3)
Investigations
Screening Test
Confirmatory Test
Localization of the Disease
Treatment
ADRENAL MEDULLA
Pheochromocytoma
Clinical Features
Diagnostic Investigations
24-hour Urinary Metabolites
Localization Studies
Preoperative Preparation of Pheochromocytoma
Intraoperative Management
Follow-up
Primary Aldosteronism
Clinical Features
Investigations and Diagnosis
Treatment
Adrenal Insufficiency (Addison's Disease)
Clinical Features
Investigations
Management
Incidentalomas
Anatomical Localization of Adrenal Tumors
SURGERY OF THE ADRENAL GLANDS
Open Surgical Approaches
Laparoscopic Adrenalectomy
40:
Multiple Endocrine Neoplasia
DEFINITIONS
MEN TYPE TYPE 1
Screening for MEN Type 1
Genetic Testing
Screening for MEN by Imaging
Treatment
MEN Type 1
MEN Type 2
Genetics: MEN Type 2
Clinical Features: MEN Type 2
Screening for MEN Type 2
Biochemical Screening
Genetic Testing
Treatment
Thyroid Disease
Follow up
SECTION 10: GASTROINTESTINAL SURGERY
41:
Acute Abdomen
INTRODUCTION
ABDOMINAL PAIN
Visceral Pain
Parietal Pain
Referred Pain
ASSESSEMENT OF THE PATIENT WITH AN ACUTE ABDOMEN (Figs 41.2 to 41.5*)
History
Pain
Vomiting
Bowel Activity
Distention of Abdomen
Problems of Micturition
History of Systemic Illness
Physical Examination
Inspection
Palpation
Percussion
Auscultation
Rectal and Pelvic Examination
Investigations
Laboratory Evaluation
Radiologic Investigations
Peritonitis
Bacteriology
Spread of the Infection
Progression of Untreated Peritonitis
Resolution of Peritonitis
Clinical Findings
Investigations
Management
Resuscitation of the Patient
Complications of Peritonitis
COMMON CAUSES OF ACUTE ABDOMEN
Gynecologic causes of the Acute Abdomen
Pelvic Inflammatory Disease and Tubo-ovarian Abscess
Ruptured Ectopic Pregnancy
Adnexal Torsion
Hemorrhagic Functional Ovarian Cysts
Nonoperative Causes of Abdominal Pain
Urolithiasis
Epididymitis
Infectious Enteritis
Spontaneous Bacterial Peritonitis
Mesenteric Adenitis
Varicella Zoster Infections
Diabetic Ketoacidosis
Porphyria
Narcotic Withdrawal
Alcohols
Lead Intoxication
Iron Intoxication
Myocardial Infarction
Pneumonia
Sickle Cell Anemia
Approach to a Child with Acute Abdomen
Assessment of the Child
Abdominal Examination
Supportive and Preoperative Medical Management in Infants and Children
Maintenance Requirements in Children
42:
Esophagus
EMBRYOLOGY
ANATOMY
PHYSIOLOGY
ESOPHAGEAL DISEASE
Symptoms
Investigative Modalities (Table 42.1)
Radiologic Studies
Esophagoscopy:
Esophageal Manometry
Esophageal pH Monitoring
Congenital Abnormalities Esophageal Atresia
Introduction
Classification
Presentation
Diagnosis
Associated Anomalies
Management
H-type (TEF without EA)
Complications
Esophageal Webs and Diverticulae
Plummer-Vinson Syndrome (Sideropenic dysphagia)
Lower Esophageal Webs (Schatzki Ring)
Esophageal Diverticulae
Foreign Bodies in the Esophagus
Perforation of the Esophagus
Causes of Perforation of the Esophagus (Table 42.4)
Clinical Features
Investigations
Treatment
Mallory-Weiss Syndrome
Treatment
Caustic Injury
Clinical Presentation
Investigations
Treatment
Benign Strictures
Clinical Presentation
Investigations
Treatment
Gastroesophageal Reflux Disease (GERD) and Sliding Hiatus Hernia
Factors Contributing to Reflux
Grading of Esophagitis
Clinical Findings
Differential Diagnosis
Investigations
Complications of GERD and Hiatus Hernia
Treatment
Paraesophageal Hernia (Rolling Hernia)
Clinical Features
Treatment
Gastroesophageal Reflux (GER) in Infants and Children
Treatment
ESOPHAGEAL MOTILITY DISORDERS
Achalasia Cardia
Pathophysiology
Clinical Features
Investigations
Differential Diagnosis
Treatment
Diffuse Esophageal Spasm
TUMORS OF THE ESOPHAGUS
Benign Tumors
Carcinoma of the Esophagus
Incidence
Risk Factors (Table 42.10)
Pathology
Patterns of Growth in Epithelial Cancers
Spread of Cancer
Clinical Features
Complications
Investigations
Screening for Carcinoma Esophagus
Treatment
Cancers of the Mid-Thoracic and Lower Thoracic Esophagus
Cancers of the Cervical Esophagus and Hypopharynx
Complications of Esophageal Resection
Palliative Procedures
Causes of Death
43:
Stomach and Duodenum
SURGICAL ANATOMY
Stomach
Arterial Supply and Venous Drainage of the Stomach
Lymphatic Drainage
Innervation
Duodenum
Physiology
Gastric Secretion
Secretion of Acid
Other Secretory Functions
Gastric Motility and Emptying
Sphincters
Investigations in Gastric and Duodenal Disease
Radiology
Endoscopy
Gastric Acid Output Study
Gastric Emptying
CONGENITAL DISEASES
Congenital Hypertrophic Pyloric Stenosis
Etiology
Clinical Features
Investigations
Management
Pyloric Atresia
Duodenal Atresia and Stenosis
Malrotation
ACQUIRED DISEASES
Peptic Ulcer
Pathophysiology
Clinical Features
Management of Peptic Ulcer
Intractable Ulcers
Surgical Options
Choice of Procedures
Complications following Peptic Ulcer Surgery (Table 43.4)
Complications of Peptic Ulcer
Zollinger-Ellison Syndrome
Erosive Mucosal Disease (EMD)
Volvulus of the Stomach
Gastric Foreign Bodies and Bezoars
NEOPLASMS OF THE STOMACH
Gastric Adenocarcinoma
Epidemiology
Molecular Genetics in Carcinoma Stomach
Pathology
Clinical Features
Investigations
Management Considerations
Surgical Resection in Advanced Gastric Cancer
Types of Gastrectomy
Morbidity and Mortality following Curative Surgery (Table 43.9)
Palliative Therapy in Gastric Cancer
Choice of Procedure
Gastric Lymphomas
Epidemiology
Pathology
Clinical Features and Diagnosis and Staging
Management and Prognosis
Soft Tissue Tumors of the Stomach
Clinical Features
Diagnosis
Surgical Management and Prognosis
Gastric Carcinoids
ACQUIRED DUODENAL DISEASES
Benign Duodenal Conditions
Duodenal Diverticula
Duodenal Injuries
Definition of key terms
Duodenal Fistula
Management Resuscitation (1st 24 hr)
Management priorities (beyond 24 hours—1 week)
Management priorities beyond the first week
Tumors of the Duodenum
Adenomas
Adenocarcinomas
Neuroendocrine Tumors
Duodenal Lymphoma
44:
Small Intestine
EMBRYOLOGY
ANATOMY
STRUCTURE OF THE SMALL INTESTINE
PHYSIOLOGY
Digestion
Immune Function
Hormonal Secretion
Intestinal Motility
INVESTIGATION OF THE SMALL INTESTINE
Structural Tests
Radiological Tests
Tests of Small Intestinal Function
Nutritional Deficiencies
Fat Absorption Tests
Carbohydrate Absorption Tests
Vitamin B12 Absorption Tests
SMALL BOWEL OBSTRUCTION
Mechanical Small Bowel Obstruction
Causes of Obstruction
Epidemiology
Types of Obstruction
Pathophysiology
Clinical Features
In Acute Obstruction
In Chronic Obstruction
In Subacute Intestinal Obstruction
In Acute-on-Chronic Obstruction
Investigations
Plain Abdominal Films in Erect and Supine Position
Treatment
Resuscitation of the Patient
Operative Management
Special Situations
ILEUS
Clinical Features
Treatment
NEONATAL GASTROINTESTINAL OBSTRUCTIONS
History
Maternal Hydramnios
Increased Salivation
Vomiting
Abdominal Distention
Passage of Meconium
Physical Findings and Radiologic Studies
Jejunoileal Atresia and Stenosis
Pathology
Etiology
Clinical Presentation
Diagnosis
Differential Diagnosis
Treatment
MECONIUM ILEUS
Clinical Presentation
Investigations
Treatment
MECONIUM PERITONITIS
MALROTATION
Clinical Features
Radiology
Treatment
Management of a Neonate with Gastrointestinal Obstruction
BLIND LOOP SYNDROME
Clinical Features
Diagnosis
Treatment
SHORT GUT SYNDROME
Pathophysiology
Clinical Features
Treatment
Medical Management
Surgical
Radiation Enteritis
SMALL INTESTINAL DIVERTICULAE
Incidence
Clinical Features
Diagnosis
Treatment
TYPHOID AND ITS SURGICAL COMPLCATIONS
Pathogenesis
Clinical Presentation
Diagnosis
Perforated Typhoid Ulcer
Pathology
Clinical Features
Treatment
Bleeding Typhoid Ulcer
Bleeding
Typhoid Cholecystitis
Acute Acalculous Cholecystitis
Chronic Typhoid Cholecystitis
Treatment
Other Complications of Typhoid
ABDOMINAL TUBERCULOSIS
Epidemiology
Pathogenesis
Pathology
Pathology
Clinical Features
Symptoms and Signs due to Specific Organ involved
Intestinal Tuberculosis
Peritoneal Tuberculosis
Glandular Tuberculosis
Other forms of Abdominal Tuberculosis
Diagnosis
Tissue Diagnosis
Radiology
Treatment
Surgical Treatment
Medical Management
Acute Intussusception in Infants and Children
Clinical Features
Diagnosis
MECKEL'S DIVERTICULUM
Clinical Features
Treatment
GASTROINTESTINAL DUPLICATIONS
Clinical Presentations
Diagnosis and Treatment
INFLAMMATORY BOWEL DISEASE
CROHN'S DISEASE
Incidence and Etiology
Pathology
Clinical Features
Investigations
Radiology
Treatment
Medical Management
Surgical Management
INGESTED FOREIGN BODIES
INTESTINAL FISTULAE
Classification
Etiology
Effects of Fistula and the Status of the Patient
Management
TUMORS OF THE SMALL INTESTINE
Benign Tumors
Adenoma
Leiomyoma
Lipoma
Peutz-Jegher's Syndrome (Hamartoma)
Hemangioma
Malignant Tumors
Clinical Features
Treatment
Carcinoid Tumors
Clinical Manifestations
Treatment
45:
Colon and Rectum
EMBRYOLOGY AND ANATOMY
The Colon
Vascular Supply
Rectum
Relations
Anorectal Ring
PHYSIOLOGY
Motility
Colonic Bacterial Flora and Bowel Preparation
CONGENITAL DISEASES OF THE LARGE BOWEL
Megacolon
Hirschsprung's Disease
Etiology
Pathology and Pathophysiology
Clinical Features
Diagnosis
Treatment
Acquired Megacolon
Diverticular Disease of the Colon
Pathophysiology
Clinical Features
Complications
Investigations
Treatment
Intestinal Amebiasis
Clinical Features
Investigations
Treatment
Complications
INFLAMMATORY BOWEL DISEASE
Ulcerative Colitis
Etiology
Pathology
Clinical Features
Local Complications
Extracolonic Manifestations
Investigations
Treatment
Medical treatment
Surgical Procedures
Complications of Surgery for Ulcerative Colitis
Ischemic Colitis
Causes of Ischemia
Pathogenesis
Clinical Features
Investigations
Treatment
Rectal Prolapse
Types of Prolapse
Clinical Features
Investigations
Treatment
Constipation and Fecal Impaction
Clinical Features
Treatment
Radiation Proctitis
Clinical Features
Treatment
VOLVULUS
Volvulus of the Sigmoid Colon
Clinical Features
Diagnosis
Treatment
Cecal Volvulus
Clinical Features
Radiology
Treatment
Transverse Colon Volvulus
TUMORS OF THE COLON
Benign Adenomatous Polyps
Neoplastic Hereditary Polyposis
Benign Tumors of the Colon and Rectum
Treatment
Malignant Carcinoma of the Colon
Etiology
Screening for Colon Cancer
Pathology
Spread of Cancer
Grading
Staging of the Tumor
Clinical Features
Investigations
Treatment for Colon Cancer
Preoperative Bowel preparation
Exploratory Laparotomy
Adjuvant Treatment
Advanced Disease
Metastatic Disease in the Liver and Lungs
Carcinoma of the Rectum
Pathology
Spread of Cancer
Staging of Rectal Carcinoma
Clinical Features
Investigations
Treatment
Prognosis
Fecal Fistula arising from the Large Bowel
Causes of Fecal Fistula
Investigations
Treatment
Prognosis
46:
Anal Canal and Minor* Anorectal Conditions
EMBRYOLOGY
ANATOMY
Anorectal Ring
Anal Sphincter Mechanism
Arterial Supply
Hemorrhoidal Complexes
Lymphatic Drainage
Innervation and Physiology
ANORECTAL ANOMALIES
Anorectal Malformation
Management of Anorectal Malformations
(MINOR) ANORECTAL CONDITIONS
Fissure in Ano (Anal Fissure)
Clinical Findings
Treatment
Hemorrhoids (Piles)
Clinical Features
Treatment
Anorectal Infection
Perianal Abscess
Ischiorectal Abscess
Submucous Abscess
Intermuscular Abscess
Pelvirectal Abscess
Treatment
Fistula in Ano
Clinical Findings
Treatment
Pilonidal Sinus
Clinical Findings
Treatment
Pruritus Ani
Clinical Features
Treatment
CANCER OF THE ANAL CANAL
Epidermoid Carcinoma
Clinical Features
Investigations
Treatment
Basal Cell Carcinoma
Adenocarcinoma
Malignant Melanoma
Treatment
47:
Appendix
SURGICAL ANATOMY
Blood Supply
Common Anatomical Positions (Fig. 47.1)
ACUTE APPENDICITIS
Etiology and Pathogenesis
Pathology
Obstructive Acute Appendicitis
Nonobstructive Acute Appendicitis
Clinical Features
Symptoms
Physical Signs
Laboratory Investigations
Symptoms and Position of the Appendix
Retrocecal Appendicitis
Pelvic Appendicitis
Preileal and Postileal Appendicitis
Subhepatic Appendicitis
Complications of Appendicitis
Appendicular Mass
Appendicular Perforation and Peritonitis
Appendicular Abscess
Suppurative Pylephlebitis
Septicemia
Appendicitis in Special Situations
Appendicitis in Neonates
Appendicitis in Young Children
Appendicitis in Young Women
Appendicitis during Pregnancy
Appendicitis in the Elderly
Treatment
Preoperative Preparation
Operative Procedures
Treatment of Appendicular Mass
Treatment of Appendicular Abscess
Complications of Appendicectomy
TUMORS OF THE APPENDIX
Carcinoid
Adenocarcinoma
Mucocele
SECTION 11: HEPATOBILIARY AND PANCREAS AND SPLEEN
48:
Liver
EMBRYOLOGY
ANATOMY
Functional Anatomy
Blood Supply and Drainage
BILIARY DRAINAGE
Microscopic Anatomy
FUNCTIONS OF THE LIVER AND LIVER FUNCTION TESTS
Liver Imaging Techniques
Other Invasive Diagnostic Investigations
DISEASES OF THE LIVER
Liver Infections
Viral Hepatitis
Cirrhosis of the Liver
Liver Abscess
Pyogenic Liver abscess
Amebic Liver Abscess (ALA)
Hydatid Disease of the Liver
Causative Agent
Life Cycle
Pathology
Clinical Features
Complications
Investigations and Diagnosis
Treatment
Other Nonparasitic Cysts of the Liver
Treatment
Biliary Atresia
Caroli's Disease
TUMORS OF THE LIVER
Benign Tumors
Hemangioma
Hamartoma
Adenoma
Focal Nodular Hyperplasia (FNH)
Malignant Tumors
Primary Malignant Tumors
Hepatoblastoma
Hepatocellular Carcinoma (Hepatoma)
Metastatic Tumors (Secondaries)
Cholangiocarcinoma
LIVER TRAUMA
PRINCIPLES AND PRACTICE OF LIVER RESECTION
Assessment of the Preoperative Functional Status of the Liver
Assessment of the Patient-related Factors
Preoperative Preparation
Operative Procedures
Methods of Temporary Vascular Control
Basic Operative Steps for Commonly Performed Liver Resections
Types of Liver Resections
Segment-oriented Resections of the Liver
Resections for Live-related Liver Transplantation (LRLT)
Postoperative Course
49:
Portal Vein
ANATOMY OF THE PORTAL VENOUS SYSTEM
PORTAL HYPERTENSION
Definition
Etiology
Prehepatic Obstruction
Portal Vein Thrombosis
Splenic Vein Thrombosis
Intrahepatic Obstruction
Posthepatic Obstruction
Pathophysiology
Increase in Plasma Volume and Cardiac Output
Portosystemic Collaterals
Ascites
Encephalopathy
Clinical Features
Upper Gastrointestinal Bleed
Splenomegaly
Ascites
Portosystemic Encephalopathy
Investigations and Diagnosis
Endoscopy
Ultrasound with Doppler Scan
Splenoportovenogram (SPV)
Measurement of Portal Pressures
Selective Visceral Angiography
Liver Function Tests
Liver Biopsy
Child's Class
Miscellaneous Investigations
Management
Acute Variceal Hemorrhage (Fig. 49.4)
Emergency Shunt Surgery
Definitive Procedures for Acute or Recurrent Bleed
Elective Surgery
Control of Ascites and Encephalopathy
50:
Gallbladder and Biliary Ducts
EMBRYOLOGY
GALLBLADDER
Structure
Biliary Ducts
Physiology
Gallbladder Function
Enterohepatic Circulation
Congenital Anomalies
Investigations in Biliary Tract Diseases
Abdominal X rays
Ultrasound
Oral Cholecystography
Computed Tomography
Radionuclide Biliary Scan
Percutaneous Transhepatic Cholangiography (PTC)
Endoscopic Retrograde Cholangiopancreatography (ERCP)
CHOLEDOCHAL CYST
Pathology
Clinical Presentation
Diagnosis and Preoperative Assessment
Complications
Surgical Treatment
BILIARY ATRESIA
Etiology
Pathology
Clinical Presentation
Evaluation and Investigations
Surgical Treatment
GALLSTONE DISEASE
Pathogenesis of Gallstones
Acute Cholecystitis
Pathogenesis
Clinical Features
Differential Diagnosis
Investigations
Radiology
Treatment of Gallstones
Acute Cholecystitis
Biliary Colic
Mucocele of the Gallbladder
Acute Acalculous Cholecystitis
Asymptomatic Stones
Emphysematous Cholecystitis
Chronic Cholecystitis
Clinical Features
Common Bile Duct Stones (Choledocholithiasis)
Clinical Features
Investigations
Treatment
Retained Common Bile Duct Stones
Biliary Enteric Fistula
Gallstone Ileus
Clinical Features
Investigations
Treatment
Hyperplastic Cholecystoses
Cholangitis
Clinical Features
Treatment
Cholangiohepatitis
Primary Sclerosing Cholangitis
Gallbladder Cancer
Etiology
Pathology
Clinical Features
Investigations
Staging
Treatment
Cholangiocarcinoma (Bile Duct Cancer)
Pathology
Clinical Features
Investigations
Treatment
Localized Extrahepatic Bile Duct Cancer
Unresectable Bile Duct Cancer
Operations on the Biliary Tract
Cholecystostomy
Open Cholecystectomy
Retrograde Cholecystectomy (Fundus-first method)
Laparoscopic Cholecystectomy
Choledocholithotomy
Biliary Leak
Clinical Features
Treatment
Benign Biliary Strictures
Other Secondary Strictures
Post-inflammatory Strictures
Ampullary or Papillary Stenosis
Primary Sclerosing Cholangitis
51:
Pancreas
EMBRYOLOGY
ANATOMY
Relations of the Pancreas
Blood Supply
PHYSIOLOGY OF THE PANCREAS
CONGENITAL ANOMALIES
Annular Pancreas
Investigations and Diagnosis
Treatment
Pancreas Divisum
Pancreatic Cysts
Ectopic Pancreas
Pancreatitis
Acute Pancreatitis
Pathology
Pathophysiology
Clinical Features
Diagnosis
Investigations
Treatment
Prognosis
Complications
Chronic Pancreatitis
Pathophysiology
Pathology
Clinical Features
Investigations
Treatment
Tropical pancreatitis (TP)
Autoimmune Pancreatitis (AIP)
Hereditary Pancreatitis (HP)
Carcinoma of the Pancreas
Risk Factors
Pathology
Spread of Tumor
Clinical Features
Investigations
Treatment
Pancreatic Endocrine Tumors
Insulinoma
Gastrinoma
Vipoma (WDHA Syndrome: Watery Diarrhea, Hypokalemia, and Achlorhydria; Pancreatic Cholera)
Glucagonoma
Somatostatinoma
Pancreatic Trauma
52:
Spleen
ANATOMY
Blood Supply
PHYSIOLOGY
Functions of the Spleen
SPLENECTOMY
Idiopathic Thrombocytopenic Purpura (ITP)
Hemolytic Anemias
Hereditary Spherocytosis
Thalassemia
Idiopathic Autoimmune Hemolytic Anemia
Hereditary Hemolytic Anemia with Enzyme Deficiency
Myeloproliferative Disorders
Hypersplenism
Causes of Hypersplenism:
Lymphoma
Ectopic Spleen
Cysts
Tumors
Abscesses
Others
Trauma to the Spleen
Clinical Features
Investigations
Treatment
SPLENECTOMY
Preoperative Preparation
Vaccination
Open Splenectomy
Complications
SECTION 12: ABDOMINAL WALL, PERITONEUM, HERNIA AND MINIMAL ACCESS SURGERY
53:
Abdominal Wall, Umbilicus, Mesentery and Omentum
ABDOMINAL WALL
Infections of the Abdominal Wall
Progressive Synergistic Gangrene (Bacterial synergistic gangrene, Meleney's ulcer)
Treatment
Rectus Sheath Hematoma (Inferior epigastric artery hematoma)
UMBILICUS
Diseases of Omphalomesenteric Duct (Fig. 53.1)
Omphalitis
Umbilical Abscess
Umbilical Fistulae
Patent Vitellointestinal Duct
Patent Urachus
Meckel's Diverticulum
Umbilical Cyst
Fibrous Cord
Exomphalos (Omphalocele)
Gastroschisis
Umbilical Granuloma (Raspberry Tumor)
Secondary Malignant Deposits
Endometriosis
MESENTERY
Diseases of Mesentery
Tuberculosis of Mesenteric Lymph Nodes
Mesenteric Cysts
Mesenteric Trauma (Tears)
OMENTUM
Diseases of Omentum
Omental Cysts
Torsion of Omentum
54:
Peritoneum and Retroperitoneum
PERITONEAL CAVITY
Anatomy
Intra-abdominal Compartments
Supracolic Compartments
Infracolic Compartment
Innervation and Blood Supply
Peritoneal Cavity Infections
Acute Peritonitis
Tuberculous Peritonitis
Intra-abdominal Abscesses
Pelvic Abscess
Interloop Abscesses
Paracolic Abscesses
RETROPERITONEUM
Anatomy
Contents of the Retroperitoneum
Retroperitoneal Tumors
Sarcomas
Idiopathic Retroperitoneal Fibrosis (Ormond's syndrome or Idiopathic fibrous retroperitonitis or sclerosing retroperitonitis)
55:
Diaphragm
EMBRYOLOGY
ANATOMY
Nerve Supply
Openings in the Diaphragm
LESIONS OF DIAPHRAGM
Diaphragmatic Hernia
Congenital*
Eventration of Diaphragm
Hernia through the Foramen of Bochdalek (Pleuroperitoneal Canal)
Hernia through the Foramen of Morgagni
Hiatus Hernia
Acquired Herniae
Traumatic Diaphragmatic Hernia
Postoperative Diaphragmatic Hernia
56:
Hernias
ANATOMY
Relations of the Inguinal Canal
Deep Ring
Superficial Ring
Contents of the Inguinal Canal
DEFINITION
Etiology
Pathophysiology
Parts of a Hernia
TYPES OF HERNIAE
Inguinal Hernia
Indirect Inguinal Hernia
Direct Inguinal Hernia
Treatment of Inguinal Hernia
Recurrence of Inguinal Hernia (Fig. 56.9)
Femoral Hernia
Differential Diagnosis
Treatment
Umbilical Hernia
Treatment
Exomphalos
Paraumbilical Hernia
Richter's Hernia
Incisional Hernia
Predisposing Factors
Clinical Features
Treatment
Recurrence of Incisional Hernia
Other Kinds of Hernias
COMPLICATIONS OF HERNIA
Irreducibility
Obstruction
Strangulation
Clinical Features
Treatment
Incarcerated Hernia
Inflamed Hernia
57:
Minimal Access Surgery
HISTORY OF LAPAROSCOPIC SURGERY
MINIMAL ACCESS SURGERY
LAPAROSCOPIC SURGERY
Contraindications of Laparoscopic Surgery
Equipment for Laparoscopic Surgery
Imaging System
Insufflator
Operative Instruments
Surgical Procedures
Laparoscopic Cholecystectomy
Ultrasonography
Diagnostic Laparoscopy
Complications of Laparoscopic Cholecystectomy
Common Bile Duct Stones
Preoperative Endoscopic Retrograde Cholangiopancreatography (ERCP) and Endoscopic Papillotomy (EPT)
Peroperative Cholangiography (POC)
Laparoscopic Extraction of CBD Stones
Inguinal Hernia
Transabdominal Preperitoneal (TAPP) Repair
Totally Extra (pre) Peritoneal (TEP) Repair
Complications of Laparoscopic Herniae repair
Acute Appendicitis
Suspected Acute Appendicitis
Operation
Laparoscopy Assisted Bowel Resection
Indications
Contraindications
Positioning of the Patient
Operative Procedure of Right Hemicolectomy
Mobilization of the Colon
Postoperative Care
Laparoscopic Adrenalectomy
Indications
Exclusion Criteria
Operative Procedure
Retroperitoneal Laparoscopic Adrenalectomy
Transperitoneal Laparoscopic Adrenalectomy
Operative Procedure
MINIMAL ACCESS SURGERY IN GASTROINTESTINAL TRACT
Peptic Ulcer Surgery
Posterior Truncal Vagotomy with Anterior Seromyotomy
Perforated Duodenal Ulcer
Gastroesophageal Reflux Disease
Laparoscopic Nissen Fundoplication
Achalasia Cardia
Bowel
Laparoscopic Surgery in Bowel Disorders
Small Bowel Obstruction
Laparoscopic Splenectomy
Indications for Surgery
Laparoscopic Splenectomy Procedures
Pancreas
Laparoscopic Management of Pancreatic Pseudocysts
Diagnostic Laparoscopy
Acute Abdomen
Chronic Abdominal Pain
Abdominal Trauma
Hepatic Cysts
Cervical Sympathectomy
Plastic Surgery
Vascular Surgery
Cardiac Surgery
Endocrine Surgery
Needlescopic Surgery
SECTION 13: PEDIATRIC SURGERY OTOLARYNGOLOGY AND OPHTHALMIC EMERGENCIES
58:
Pediatric Surgery
NEONATAL PHYSIOLOGY
Classification of Neonates
Specific Physiologic Adaptation Processes in the Neonate
Metabolic Adaptations
Adaptation of Respiratory System
Adaptation of the Cardiovascular System
Adaptation of Blood Volumes
Adaptation of Thermal Control
Fluid and Electrolyte Adaptations
RESPIRATORY DISTRESS
Congenital Diaphragmatic Hernia
Pathology and Pathophysiology
Presentation and Diagnosis
Investigations
Treatment
Eventration of Diaphragm
NEONATAL NECROTIZING ENTEROCOLITIS
PEDIATRIC SOLID TUMORS
Wilms’ Tumor and other Pediatric Renal Tumors
Molecular Biology and Genetics
Pathology
Clinical Presentation
Diagnosis and Investigations
Staging and Prognostic Considerations
Therapy for Wilms’ Tumors
Bilateral Wilms’ Tumor (BWT)
Follow-up after Completion of Therapy
Results of Treatment of Wilms’ Tumor
Neuroblastoma
Epidemiology
Pathology
Clinical Presentation
Diagnosis and Initial Evaluation
Staging
Treatment of Neuroblastoma
Rhabdomyosarcoma in Children
Pathology
Clinical Staging
Patterns of Spread
Principles of Treatment of Rhabdomyosarcoma
Germ Cell Tumors
Pathology
Clinical Markers
Treatment of Germ Cell Tumors
Clinical Presentation and Treatment of Ovarian Germ Cell Tumors
Clinical Presentation and Treatment of Testicular Germ Cell Tumors
Clinical Presentation and Treatment of Extragonadal Germ Cell Tumors
59:
Emergencies of Ear, Nose and Throat
FOREIGN BODIES
Foreign Bodies in the Nose
Clinical Features
Management
Foreign Bodies in the Ear
Clinical Features
Diagnosis and Treatment
Foreign Bodies in the Oropharynx and Hypopharynx
Clinical Features
Investigations and Diagnosis
Treatment
Foreign Bodies in the Esophagus
Clinical Features
Investigations and Diagnosis
Treatment
Airway Foreign Bodies
Clinical Features
Investigations and Diagnosis
NECK TRAUMA
Clinical Features of Acute Laryngotracheal Trauma
Assessment of a Patient
Management
Contusions
Fracture of Hyoid Bone
Thyroid and Cricoid Cartilage Fractures
Laryngotracheal Separation
Cervical Spine Injury
Injury of Major Vessels in Neck
Injury to Pharynx and Esophagus
Injury to Submandibular Gland and Thyroid Gland
AIRWAY OBSTRUCTION
Medical Management
Heimlich Maneuver and Positioning Maneuvers
Carotid Blow-out
EPISTAXIS
Management
Ancillary Management
DEEP NECK INFECTIONS
Fascial Spaces
Infection of Spaces involving the Entire Length of Neck
Infection of Spaces above the Hyoid Bone
Infection of Spaces below the Hyoid Bone
FACIOMAXILLARY TRAUMA
Scalp and Facial Injuries
Nasal Fractures
Ear Trauma
External Ear Trauma
Middle Ear Trauma
Inner Ear Injury
Midface Fractures
Lateral Middle Third Fractures
Zygomaticomaxillary Fracture
Orbital Blow-out Fracture
Frontal Sinus Fractures
Mandible Fractures
CSF Otorrhea
CSF Rhinorrhea
60:
Ophthalmic Emergencies
GENERAL APPROACH TO OPHTHALMIC EMERGENCIES
MAJOR OPHTHALMIC EMERGENCIES OR OPHTHALMIC EMERGENCY ‘SYNDROMES’
Acute Red Eye
Conjunctivitis
Corneal Abrasion
Corneal Foreign Body
Corneal Ulcers
Acute Iridocyclitis
Acute Angle Closure Glaucoma
Sudden Loss of Vision
Acute Painful Eye
Acute Swelling of the Eye
Acute Trauma to the Eye
Chemical Injuries
SECTION 14: ORTHOPEDICS
61:
General Principles of Fracture Management
INTRODUCTION
ANATOMY OF BONE
Types of Cartilage
Types of Bones
Based on Development
Based on Structure
Structure of Bone
Parts of a Long Bone
Bone Cells
Functions of Bone
FRACTURE
Classification of Fractures
Mechanism of Fracture Displacement
Compound Fracture
Classification of Compound Fractures
Bone Repair and Fracture Healing
Clinical Feature of Fractures
History
General Signs
Local Examination
Movement
Examination of Neighboring Joints
Investigation
How to read Radiographs in Bony Trauma?
Clinical Diagnosis
Management of Closed Fractures
Management at the Site of Accident
Management in Emergency Room (Casualty)
Closed Reduction
Methods of closed reduction
Contraindication of closed reduction
Open Reduction
Immobilization
Management by Internal Fixation
Management of Open Fractures
Treatment of Open Fracture
Complications of Fractures
Epiphyseal Injury
Classification of Opiphyseal Injuries
62:
Fractures of the Upper Limb
FRACTURE OF THE CLAVICLE
Mode of Injury
Fracture
Treatment
Complications
Dislocation of Sternoclavicular Joint
Treatment
Injuries of the Acromioclavicular Joint
Mode of Injury
Treatment
FRACTURE OF SCAPULA
Fractures of Body of Scapula
Treatment
Dislocation of the Shoulder
Anterior Dislocation
Classification
Clinical Features
Radiology
Treatment
Complications
Posterior Dislocation of Shoulder
FRACTURE OF THE ARM
Fractures of the Surgical Neck of the Humerus
Mode of Injury
Treatment
Complications
Fracture of the Greater Tuberosity of the Humerus
Treatment
Complications
Fracture of the Shaft of Humerus
Mode of Injury
Treatment
Complications
Fractures around the Elbow
Supracondylar Fracture of the Humerus
Mechanism of Injury
Displacements
Clinical Presentation
Treatment
Complications
Fracture of the Lateral Condyle of Humerus
Mechanism of Injury
Treatment
Complications
Intercondylar Fracture of the Humerus
Treatment
Complications
Fracture of the Medial Epicondyle
Treatment
Pulled Elbow
Mechanism of Injury
Treatment
FRACTURES OF THE FOREARM
Fracture of Olecranon
Mechanism of Injury
Treatment
Complications
Fracture of Head of the Radius
Mechanism of Injury
Clinical Features
Treatment
Fracture of Neck of the Radius
Treatment
Fracture of Capitullum
Treatment
ELBOW JOINT
Dislocation of Elbow
Mechanism of Injury
Clinical Features
Treatment
Complications
Fracture of Forearm Bones
Mechanism of Injury
Clinical Features
Treatment
Complications
Monteggia Fracture Dislocation
Clinical Features
Treatment
Complication
Galeazzi Fracture Dislocation
Mechanism of Injury
Treatment
FRACTURES OF WRIST JOINT
Colles’ Fracture
Mechanism of Injury
Clinical Features
Treatment
Complications
Smith's Fracture
Barton's Fracture
Scaphoid Fracture
Mode of Injury
Clinical Features
Radiological Examination
Treatment
Complications
Lunate Dislocations
Treatment
Bennett's Fracture Dislocation
Mode of Injury
Rolando's Fracture
Metacarpal Fracture
Treatment
Phalangeal Fracture
Mallet (baseball) Fingers
Clinical Features
Treatment (Fig. 62.15)
Gamekeeper's Thumb
63:
Fractures of the Lower Limb
FRACTURES OF THE PELVIS
Classification
Type I Fractures
Type II Fractures
Type III Fractures
Type IV Fractures
Complications of Pelvic Fractures
FRACTURE AND DISLOCATIONS OF HIP
Classification
Posterior Hip Dislocations
Anterior Dislocation of Hip
Central Fracture Dislocation of Hip
Complications of Fractures and Dislocations of the Hip
FRACTURES OF NECK OF THE FEMUR
Classification
Diagnosis
Treatment
Indications for Hemiarthroplasty
Complications of Fracture of Neck of Femur
INTERTROCHANTERIC FRACTURES
Diagnosis
Classification
Treatment
Complications
SUBTROCHANTERIC FRACTURES
Classification
Treatment
Operative Treatment
Nonoperative Treatment
Complications
FRACTURES OF THE SHAFT OF THE FEMUR
Classification
Diagnosis
Treatment
Complications
FRACTURES OF THE DISTAL THIRD OF THE FEMUR
Classifications
Treatment
Complications
INTERCONDYLAR FRACTURES
Classification
Treatment
Complications
FRACTURES OF FEMORAL CONDYLES
Classification
Treatment
FRACTURES OF THE PATELLA
Diagnosis
Classification
Treatment
Conservative Treatment
Operative Treatment
Complications
FRACTURES OF THE PROXIMAL TIBIA
Classification
Treatment
Complications
KNEE DISLOCATION
Classification
Treatment
Complications
FRACTURES OF TIBIA AND FIBULA
Diagnosis
Classification
Treatment
Complications
FRACTURES AND DISLOCATIONS OF THE ANKLE
Classification
Abduction Injuries
Adduction Injuries
External Rotation Injuries with Inferior Tibiofibular Joint Diastasis (Pronation, External Rotation Injuries)
External Rotation Injury without Diastasis of the Inferior Tibiofibular Joint (Supination, External Rotation Injuries)
Vertical Compression Injuries of the Ankle
FRACTURES AND DISLOCATIONS OF THE FOOT
Fractures of the Talus
Classification
Treatment
Complication
Fractures of the Calcaneus
Classification
Treatment
Complications
Injuries of the Midtarsal Joints
Classification
Treatment
Complications
Injuries of the Tarsometatarsal Joints
Classification
Treatment
Complications
Fractures of the Metatarsals
Treatment
Complications
Fractures of the Toes
Treatment
Complication
March Fracture
Clinical Features
Radiology
Treatment
Jone's Fracture
64:
Congenital Deformities and Degenerative Disorders of the Musculoskeletal System
INTRODUCTION
CLASSIFICATION
CONGENITAL DEFORMITIES OF THE LOWER LIMB
Congenital Talipes Equinovarus (Club Foot)
Introduction
Etiology
Pathoanatomy
Clinical Features
Diagnosis and Radiological Assessment
Treatment
Congenital Vertical Talus
Pathoanatomy
Clinical and Radiological Features
Treatment
Congenital Pseudoarthrosis of Tibia and Fibula
Treatment
Congenital Dislocation of the Hip
Incidence and Etiology
Pathoanatomy
Clinical Features and Diagnosis
Radiology for DDH
Treatment
Congenital Dislocation of Patella
Polydactyly of Toes
Macrodactyly of Toes
Congenital Cleft Foot
Congenital Metatarsus Adductus (CMA)
CONGENITAL DEFORMITIES OF THE UPPER LIMB
Congenital Radial Club Hand
Pathoanatomy
Classification
Clinical Features
Treatment
Congenital Radioulnar Synostosis
Congenital Ring Syndrome
Polydactyly of the Thumb
Polydactyly of the Little Finger
Macrodactyly
Syndactyly
CONGENITAL DEFORMITIES OF THE TRUNK
Congenital Torticollis
Congenital High Scapula
Congenital Pseudoarthrosis of the clavicle
Congenital Short Neck
CONGENITAL VERTEBRAL DEFORMITIES
Congenital Scoliosis
Congenital Kyphosis
DEGENERATIVE DISEASE OF THE KNEE JOINT
DEGENERATIVE DISEASE OF THE HIP JOINT
DEGENERATIVE DISORDERS OF THE SPINES
Cervical Spondylosis
Lumbar Spondylosis
65:
Infections of Bones and Joints
OSTEOMYELITIS
Classification of Osteomyelitis
Mode of Spread of Infection
Acute Osteomyelitis
Acute Hematogenous Osteomyelitis
Acute Osteomyelitis by Direct Inoculation
Chronic Osteomyelitis
Classification of Chronic Osteomyelitis
Physiologic status
Diagnosis and Evaluation
Diagnosis of Acute Osteomyelitis
Differential Diagnosis
Treatment of Acute Osteomyelitis
Surgical Treatment
Complications of Acute Osteomyelitis
Treatment of Chronic Osteomyelitis
Surgical Treatment
Complications of Chronic Osteomyelitis
Septic Arthritis
Septic Arthritis of Hip Joint
Complications of septic arthritis of hip joint
Tubercular Arthritis
Arthritis of Major Joints due to Tuberculosis
Tuberculosis of Hip Joint
Clinical Features
Differential Diagnosis
Radiology
Treatment
Tuberculosis of Knee Joint
Clinical Features
Diagnosis
Differential Diagnosis
Treatment
SOME UNCOMMON BONE AND JOINT INFECTIONS
Salmonella Osteomyelitis
Diagnosis
Treatment
Mycetoma
Clinical Features
Treatment
Leprosy
Treatment
66:
The Spine
INJURIES OF THE SPINE
Neurological Injuries
Primary
Secondary
Pattern of Neurological Injuries
Complete Neurological Deficit
Incomplete Neurological Deficit
CERVICAL SPINE INJURIES
Surgical Anatomy
Biomechanical Considerations
Classification of Cervical Spine Injuries
Upper Cervical Spine Injuries
Lower Cervical Spine Injuries
Initial Evaluation and Management
History
Physical Examination
Radiological Examination
Management of Cervical Spine Injuries
Thoracolumbar Spine Injuries
Biomechanics
Denis Three-column Concept
Classification
Compression Fractures
Burst Fractures
Seat-belt Type Injuries
Fracture Dislocation
Radiological Findings
Treatment
Pharmacological Treatment
Nonoperative Treatment
Timing of Surgery
Operative Treatment
Comprehensive Care of Tetraplegics and Paraplegics
Physical Rehabilitation
Occupational Therapy
Social Rehabilitation
Vocational Rehabilitation
Sexual Rehabilitation
Classification and Management of Bladder in Spinal Cord Injuries
Shock Bladder
Automatic Bladder (Reflex Bladder, UMN Type Bladder)
Autonomous Bladder (Cauda Equina Bladder, LMN Type Bladder)
Management and Conditioning of the Bladder Disorders
Bowel Care
Complications in Quadriplegics and Paraplegics and their Management
Pulmonary Complications
Gastrointestinal Complications
Urologic Complications
Pressure Sores
Osteoporosis, Hypercalcemia and Fractures
Heterotr ophic Ossification
Autonomic Dysreflexia
DEFORMITIES OF SPINE
Scoliosis
Classification
Pathology
Clinical Features
Investigation
Treatment
Idiopathic curve
Kyphosis
Spondylolisthesis
Pathology
Types of Spondylosisthesis
Treatment
VERTEBRAL TUBERCULOSIS
Pott's paraplegia
Treatment
Operative Treatment
Spinal Tumors
Neurilemoma and Neurofibroma
Meningioma
Ependymoma
Astrocytoma
Lipoma
Dermoid
Metastatic Tumor
Clinical presentation
Diagnosis
Treatment
Peripheral Nerve Tumors
Schwannoma
Neurofibroma
Spinal Dysraphism
67:
Tumors of Bones and Joints
BONE TUMOR
APPROACH TO A PATIENT WITH BONE TUMOR
Benign and Malignant Bone Tumors
Primary Bone Tumor versus Primary Soft Tissue Tumor
Bone Tumors and Age Distribution
Staging of Bone Tumors
OSTEOBLASTIC TUMORS
Enostosis (bone island)
Radiology
Osteoma
Clinical Features
Radiology
Osteoid Osteoma
Pathology
Clinical Features
Radiology
Differential Diagnosis
Management
Complications of Treatment
Osteoblastoma
Clinical Features
Radiology
Differential Diagnosis
Management of Osteoblastoma
Osteosarcoma
Pathology
Classification
Histologic Subtypes
Mode of Spread
Clinical features
Investigations
Treatment
CHONDROBLASTIC TUMORS
Osteochondroma
Multiple Hereditary Exostosis
Clinical Features
Management
Enchondroma
Clinical Features
Radiology
Differential Diagnosis
Treatment
Chondrosarcoma
Clinical Features
Treatment
Fibrous Dysplasia
Radiology
Biopsy
Treatment
Simple Bone Cyst
Sites of Involvement
Pathology
Clinical Features
Radiology
Treatment
Aneurysmal Bone Cyst
Pathology
Clinical Features
Radiology
Treatment
Giant Cell Tumor
Pathology
Clinical Features
Radiology
Differential Diagnosis
Treatment
Ewing's Sarcoma
Clinical Features
Pathology
Treatment
Multiple Myeloma
Pathology
Clinical Features
Investigations
Management
Tumor Metastasis in Bones
Investigation
Treatment
SECTION 15: GYNECOLOGY
68:
Gynecology for Surgeons
ECTOPIC PREGNANCY
Pathology
Etiology
Pelvic Inflammatory Disease
Previous Surgery on Fallopian Tube
Contraceptive Use
Extrinsic Pressure on Fallopian Tubes
Clinical Features
Physical Signs
Investigations and Diagnosis
Urine Pregnancy Test
Ultrasonography
Serum HCG Estimation
Ultrasound and Serum HCG value—a Combined Approach
Aspiration from Pouch of Douglas [Culdocentesis]
Diagnostic Laparoscopy
Laparotomy
Treatment
Salpingectomy
Conservative Surgical Procedure on Affected Tube
Linear Salpingotomy
Partial Salpingectomy
Nonsurgical Treatment for Ectopic Pregnancy
FIBROID (LEIOMYOMA) UTERUS
Pathology
Gross Pathology
Degenerative Changes in Fibroids
Symptoms and Signs
Rare Presentations of Fibroids
Investigations
Ultrasonography
Treatment of Fibroid Uterus
Expectant Treatment
Surgical Removal
Surgical Steps for Abdominal Hysterectomy
Surgical Steps for Removal of Fibroid (Myomectomy)
OVARIAN CYSTS AND OVARIAN NEOPLASMS
Neoplastic Cysts of Ovary
Dermoid Cysts of Ovary
Serous Cystadenoma
Mucinous Cystadenoma (Pseudomucinous Cyst)
Ovarian Malignancy
PELVIC PERITONITIS
PELVIC ABSCESS
Surgical Treatment of Pelvic Abscess
ABNORMAL VAGINAL BLEEDING
Types of Abnormal Vaginal Bleeding
Abnormal Uterine Bleeding in Young Girls
Puberty Menorrhagia
Painful Menses (Dysmenorrhea)
Oligomenorrhea (Prolonged cycles)
Ovarian Tumors
Pregnancy Related Complications
Abnormal Vaginal Bleeding in Women of Reproductive Age Group
Fibroid Uterus
Endometriosis and Adenomyosis
Intrauterine Contraceptive Device
Dysfunctional Uterine Bleeding
Genital Tract Malignancies (Carcinoma cervix, carcinoma endometrium, etc.)
Abnormal Vaginal Bleeding after Menopause
Carcinoma Cervix
Carcinoma Endometrium
Hormone Replacement Therapy
Approach to Management of Abnormal Vaginal Bleeding
Dilatation and Curettage
Fractional Curettage
69:
Contraception
METHODS OF CONTRACEPTION
Natural Method
Coitus Interruptus
Lactational Amenorrhea Method (LAM)
Barrier Methods
Male Condom
Vaginal Diaphragm
Occlusive Cervical Cap
Vaginal Sponge
Spermicides
Female Condom (Femshield, ‘Reality’)
Intrauterine Contraceptive Devices
Mechanism of Action of IUCDs
Insertion of IUCD
Side Effects and Complications
Hormonal Contraception
Oral
Combined Oral Contraceptive (COC)
Mechanism of Action
Contraindication
Administration
Side Effects and Complications
Noncontraceptive Benefits of COC
Efficacy
Progesterone only Contraceptive
Progesterone only Pill (POP, Minipill)
Indications
Side Effects
Efficacy
Injectable Hormonal Contraception
Side Effect
Hormonal Implants
Side Effects of Implants
Hormonal Vaginal Rings
Emergency Contraception
Side Effects
Centchroman
Immunological Methods
Sterilization
Female Sterilization
Timing of Tubal Ligation
Minilaparotomy
Vaginal Ligation (Colpotomy and Tubal Ligation)
Laparoscopic Sterilization
Preoperative Assessment
Contraindications to Laparoscopic Sterilization
Procedure
Methods of Tubal Occlusion at Laparoscopy
Complications of Laparoscopic Sterilization
Chemical Methods of Sterilization
Male Sterilization
Vasectomy
Conventional Vasectomy
Complications
70:
Infertility
CAUSES OF INFERTILITY
Male Factor
Evaluation of Male Infertility
Female Factors
Ovulatory Factor
Tubal/peritoneal Factors
Uterine Factor
Cervical Factors
Immunological Factor
Unexplained Infertility
WORK-UP OF A COUPLE WITH INFERTILITY
Evaluation
Treatment
Male Factors
Female Factors
SECTION 16: UROLOGY
71:
Kidney and Ureter
EMBRYOLOGY
ANATOMY
Kidney
Relations of the Kidney
Blood Supply
Lymph Drainage
URETER
Blood Supply
INVESTIGATION OF THE URINARY TRACT
Laboratory Tests
Urine Examination
Blood Urea and Creatinine Levels
Radiology
Radionuclide Imaging
Endoscopy
CONGENITAL ANOMALIES OF THE KIDNEY AND URETER
Bilateral Renal Agenesis
Unilateral Agenesis
Ectopic Kidney
Horseshoe Kidney (Fig. 71.4C)
Clinical Features
Cystic Disease of the Kidney
Simple Cysts
Autosomal Recessive (infantile) Polycystic Kidney Disease
Autosomal Dominant (adult) Polycystic Kidney Disease (DPK)
Clinical Features
Diagnosis
Treatment
Multicystic Kidney (Multicystic dysplasia)
Anomalous Renal Artery
Presentation
Ureteropelvic Junction Obstruction (UPJO, PUJ)
Etiology
Presentation
Diagnosis
Treatment
Ectopic Ureter
Clinical Presentation
Diagnosis
Treatment
Megaureter
Clinical Presentation
Diagnosis
Treatment
Ureterocele
Clinical Presentation
Diagnosis
Treatment
Vesicoureteral Reflux (VUR)
Clinical Presentation
Evaluation
Treatment
Retrocaval Ureter
Diagnosis
Treatment
INJURIES TO THE KIDNEY
Clinical Features
Investigations
Treatment
INJURY TO THE URETER
Evaluation
Treatment
OBSTRUCTION IN THE URETER
URINARY LITHIASIS
Etiology
Risk Factors
Causes of Stone Disease
Matrix of Stone
Nephrocalcinosis
Varieties of Urinary Calculi
Clinical Features
Differential Diagnosis
Investigations
Urinalysis
Metabolic Evaluation
Plain X-ray
Intravenous Urography
Ultrasound Examination
Computed Tomography
TREATMENT OF KIDNEY STONES
Methods of Stone Removal
Open Surgery
Extracorporeal Shock Wave Lithotripsy (ESWL)
Percutaneous Nephrolithotripsy (PCNL)
Ureterorenoscopy (URS)
Treatment of Bilateral Renal Calculi
Prevention of Recurrence of Renal Calculi
URETERIC STONE
Clinical Features
Investigations
Treatment
Operative Treatment
VESICAL STONE
INFECTIONS OF THE KIDNEY
Acute Pyelonephritis
Clinical Features
Differential Diagnosis
Investigations
Treatment
Emphysematous Pyelonephritis
Etiology
Clinical Features
Investigations
Treatment
Gram-negative Bacteremia
Chronic Pyelonephritis
Clinical Features
Investigations
Treatment
Pyonephrosis
Clinical Features
Investigations
Management
Perinephric Abscess
Clinical Presentation
Investigations
Treatment
Renal Abscess
Etiology
Clinical Presentation
Investigations
Treatment
Xanthogranulomatous Pyelonephritis
Etiology
Clinical Presentation
Investigations
Treatment
Genitourinary Malacoplakia
Etiology
Clinical Presentation
Treatment
Tuberculosis of the Kidney
Pathology
Clinical Features
Investigations
Treatment
NEOPLASMS OF THE KIDNEY
Nephroblastoma (Wilms’ Tumor)
Renal Cell Carcinoma
Pathology
Clinical features (Table 71.3)
Diagnosis
Staging
Prognostic Factors
Treatment
Prognosis
Other Tumors of the Kidney
Renal Oncocytoma
Angiomyolipoma (Renal Hamartoma)
Renal Pelvic and Ureteral Tumors
72:
Urinary Bladder and Prostate
ANATOMY
Urinary bladder
Prostate Gland
CONGENITAL DISORDERS OF URINARY BLADDER
Persistent Urachus
Etiology
Complications
Treatment
Ectopia Vesicae or Exostrophy of Bladder
Embryology
Clinical Features
Associated Findings
Treatment
Adult Exstrophy
Inflammatory Conditions (Cystitis)
Acute Cystitis
Etiology
Clinical Features
Investigations
Treatment
Chronic Cystitis
Etiology
Investigations
Treatment
Tubercular Cystitis
Pathogenesis
Treatment
Sequelae
Schistosomiasis
Etiology
Clinical Features
Investigations
Treatment
Calculus Disease
Etiology
Clinical Features
Investigation
Treatment
Diverticulum of the Bladder
Causes
Clinical Features
Treatment
Foreign Body in Bladder and Urethra
Diagnosis
Treatment
Bladder Trauma
Mode of Injury
Clinical Presentation
Investigations
Treatment
Bladder Injury during Childbirth
Bladder Outlet Obstruction
Clinical Presentation
Investigations
Treatment
Urinary Incontinence
Treatment
Malignancy
Staging
Clinical Presentation
Evaluation
Management
PROSTATE
Prostatitis
Classification
Acute Bacterial Prostatitis
Chronic Bacterial Prostatitis
Nonbacterial Prostatitis
Prostatic Calculi
Clinical Presentation
Investigations
Treatment
Benign Prostatic Hypertrophy
Etiology
Clinical Presentation
Clinical Examination
Investigations
Indications for Surgery for BPH
Treatment
Prostate Cancer
Staging of Prostate Cancer (Fig. 72.15)
Clinical Presentation
Prostatic Intraepithelial Neoplasia (PIN)
Investigations
Treatment
73:
Testis and Scrotum
ANATOMY
Testicular Descent
Fate of the Testes
Clinical Presentation
Investigations
Treatment
Hormone Therapy
Surgical Management
Cryptorchidism (Bilateral Undescended Testes)
TORSION OF THE TESTIS (SPERMATIC CORD)
Clinical Features
Investigations
Treatment
Prognosis
VARICOCELE
Clinical Features
Treatment
HYDROCELE
Investigations
Treatment
Idiopathic Hydrocele
Secondary Hydrocele
EPIDIDYMO-ORCHITIS
Acute Epididymo-orchitis
Clinical Presentation
Investigations
Treatment
Chronic Epididymo-orchitis
Investigations
Treatment
TESTICULAR TUMORS
Classification
Epidemiology
Age
Cryptorchidism
Pathology
Spread of Testicular Tumor
Diagnosis
Symptoms
Signs
Laboratory Tests
Imaging
Stage
Treatment
Radical Orchidectomy
Seminoma
Nonseminomatous Germ Cell Tumors
Nongerm Cell Tumors
74:
Penis and Urethra
ANATOMY
Arterial Supply
Venous Drainage
Lymphatic Drainage
Nerve Supply
PENIS
Congenital Anomalies
Micropenis
Chordee
Epispadias
Phimosis
Paraphimosis
Hypospadias
Infections and Inflammations
Furunculosis
Balanitis
Posthitis
Balanitis Xerotica Obliterans
Condyloma Accuminatum (Genital Warts or Venereal Warts)
Giant Condyloma
Fournier's Gangrene
Penile and Scrotal Filariasis
Penile Trauma
Penile Tumors
Cancer of the Penis
Miscellaneous Conditions
Priapism
Peyronie's Disease
Erectile Dysfunction (Impotence)
URETHRA
Congenital Anomalies
Duplication of the Urethra
Megalourethra
Urethral Strictures
Posterior Urethral Valves
Acquired Disorders
Meatal Stenosis
Urethral Stenosis
Urethral Caruncle
Urethral Trauma
Urethral Strictures
SECTION 17: VASCULAR SURGERY
75:
Lymphatics and Lymph Nodes
ANATOMY
PHYSIOLOGY
LYMPHATICS
Lymphangioma
LYMPHEDEMA
Primary Lymphedema
Secondary Lymphedema
Pathology
Clinical Staging of Lymphedema (Chatterjee, 1965)
Differential Diagnosis
Investigations
Treatment
Complications
LYMPHANGITIS
Acute Lymphangitis
LYMPH NODE
LYMPHOMAS
Hodgkin's (Lymphoma or) Disease (HD)
Clinical Features
Pathology
Clinical Staging
Investigations
Treatment
Non-Hodgkin's Lymphoma (NHL)
Classification
Spread
Clinical Features
Staging
Treatment
76:
Arteries
ACUTE ARTERIAL OCCLUSION
Trauma
Management
Embolic Occlusion
Clinical Features
Treatment
Air Embolism
Gangrene
Progression of Gangrene
Types of Gangrene
Management
Aneurysms
Types of Aneurysms
Clinical Features
Investigations
Treatment
Arteriovenous Fistula
Pathophysiology
Clinical Features
Investigations
Treatment
Thoracic Outlet Syndrome (Scalene Anticus Syndrome, Cervical Rib Syndrome TOS)
Anatomy
Pathology
Clinical Features
Investigations
Treatment
Arteritis (Thromboangiitis Obliterans Buerger's Disease)
Pathology
Clinical Features
Investigations
Treatment
Raynaud's Syndrome
Investigations
Treatment
Peripheral Vascular Disease (Chronic Arterial Disease)
Clinical Features
Differential Diagnosis
Investigations
Management of Chronic Peripheral Vascular Disease (Fig. 76.22)
Amputations
Critical Limb Ischemia
Investigation
Management
77:
Veins
VARICOSE VEINS
Etiology
Pathophysiology
Muscle Pump
Venous Valves
Clinical Features
Symptoms
Examination
Investigations
Venogram
Color Doppler
Pitfalls in the Diagnosis
Treatment
Conservative Treatment
Surgical Treatment
Complications of Varicose Veins
Treatment
Operative Management
Outcome
VENOUS THROMBOSIS
Deep Vein Thrombosis (DVT or Phlebothrombosis)
Predisposing Factors Patients Related
Pathologic Conditions
Pathophysiology
Clinical Features
Investigations
Pitfalls in the Diagnosis of DVT
Management Prevention of DVT
Treatment of Established DVT
Management of DVT during Pregnancy
Outcome
Thrombophlebitis (Superficial Venous Thrombosis)
Clinical Features
Treatment
Differential Diagnosis
Outcome
Venous Hemorrhage
Treatment
78:
Pulmonary Embolism
PULMONARY EMBOLISM
Etiology
Pathology and Pathogenesis
Clinical Presentation
Acute Pulmonary Embolism
Investigations
Differential Diagnosis
Treatment
Pulmonary Infarction
Paradoxical Embolism
Chronic/Recurrent Pulmonary Emboli
Diagnosis
Management
NONTHROMBOEMBOLIC PULMONARY EMBOLISM
Pulmonary Gas Embolism
Prevention and Treatment
Pulmonary Fat Embolism
Clinical Features
Investigations
Treatment
79:
Amputation, Rehabilitation and Reimplantation
INDICATIONS FOR AMPUTATION
TECHNIQUES OF AMPUTATION
Preoperative Assessment of the Limb
Informed Consent
Anesthesia and Preparation
Surgical Technique
LOWER LIMB AMPUTATIONS (FIG. 79.1)
Toe Amputation (Ray amputation)
Transmetatarsal Amputation
Transtarsal Amputations (Chopart, Lisfranc)
Syme's Amputation
Below Knee Amputation
Through-knee Amputation (Knee Disarticulation)
Gritti-Stokes Amputation
Above Knee Amputation
Hip Disarticulation and Hemipelvectomy
UPPER LIMB AMPUTATIONS (Fig. 79.8)
Finger and Partial Hand Amputation
Forearm Amputation
Elbow Disarticulation
Above Elbow Amputation
Shoulder Disarticulation and Forequarter Amputation
Postoperative Care of Amputated Stump
COMPLICATIONS OF AMPUTATION SURGERY
Early Complications
Late Complications
REHABILITATION AFTER LIMB AMPUTATION
Preoperative Assessment and Counseling
Postoperative Assessment and Care
Prosthetic Assessment
Prosthetic Fitting
Prosthesis
Upper Extremity Prosthesis
Lower Extremity Prosthesis
Below Knee Amputation
Knee Disarticulation Prosthesis
Above-Knee Prosthesis
REIMPLANTATION
Care of the Amputated Part
Patient Selection
Surgical Technique
Preparation of the Amputated Digit or Organ
Preparation of the Patient for Reimplantation
Major Limb Reimplantation
Postoperative Management
SECTION 18: THORACIC SURGERY
80:
Lungs, Pleura and Chest Wall
ANATOMY
Thorax
Pleura
Lungs
INVESTIGATIONS OF A CHEST CASE
Sputum Analysis
Radiology
Chest Radiography
Computed Tomography (CT Scan)
Bronchoscopy
Mediastinoscopy
Thoracoscopy
Pulmonary Function Tests
Arterial Blood Gases
Pulmonary Angiography
CHEST
Chest Injuries
Rib Fractures
Flail Chest
Pneumothorax
Tension Pneumothorax
Hemothorax
Tracheobronchial Injuries
Pulmonary Parenchymal Injuries
Injuries to Mediastinal Structures
Aorta
Heart
Esophagus
Diaphragm
Penetrating Trauma of the Chest
Emergency Room Thoracotomy
Role of Thoracoscopy in Thoracic Trauma
PLEURA
Pleural Effusion
Benign Effusions
Malignant Effusion
Pneumothorax
Empyema
Causes of Empyema Thoracis
Clinical Features
Investigations
Radiology
Laboratory Investigations
TREATMENT
Prevention of Empyema
Medical Therapy
Chylothorax
Mesothelioma
THE LUNG
Hemoptysis
Bronchiectasis
Tuberculosis
Mycobacteria
Mode of Transmission
Pathogenesis
Pathology
Clinical Presentation
Investigations and Diagnosis
Treatment of Tuberculosis
Treatment of Tuberculous Infection
Surgery for Pulmonary Tuberculosis
Lung Abscess
Medical Management
Pulmonary Neoplasms
Histological Classification (Table 80.5)
Spread
Clinical Manifestations
Diagnostic Work-up
Staging of Lung Cancer
Management
Prognosis
Solitary Pulmonary Nodule
CHEST WALL
Congenital Anomalies
Cervical Rib
Pectus Excavatum
Pectus Carinatum (Pigeon chest)
Tumors of the Chest Wall
Miscellaneous
81:
Mediastinum
ANATOMY
CLINICAL PRESENTATIONS OF MEDIASTINAL MASSES
Anterior and Superior Mediastinum
Thyroid
Lymphoma
Thymus
Thymic Tumors
Parathyroid Adenoma
Teratoma
Germ Cell Tumors
Posterior Mediastinum
Neurogenic Tumors
Paraganglionomas
Pleuropericardial Cysts
Cystic Duplications of the Foregut
Bronchogenic Cysts
Enterogenous Cysts
Thoracic Meningocele
Management
Mediastinitis
Clinical Features
Management
SECTION 19: CARDIAC SURGERY AND NEUROSURGERY
82:
Cardiac Surgery
CARDIOPULMONARY BYPASS
Components of Cardiopulmonary Bypass (Fig. 82.1)
Oxygenator
Pumps
Venous Cannulae
Arterial Cannulae
Venting System
Cardioplegia
Conduct of the Cardiopulmonary Bypass
Complications of Cardiopulmonary Bypass
Bleeding
Emboli and Thrombi
Organ Dysfunction
Postpericardiotomy Syndrome
Deep Hypothermia and Circulatory Arrest
CONGENITAL HEART DISEASE
Cardiac Development
Classification
Atrial Septal Defects
Ventricular Septal Defect
Patent Ductus Arteriosus (PDA)
Atrioventricular Canal Defect (Endocardial Cushion Defect, AV Canal Defect)
Tetralogy of Fallot (TOF)
Total Anomalous Pulmonary Venous Connection
Complete Transposition of the Great Arteries (TGA)
Coarctation of Aorta
Interrupted Aortic Arch
VALVULAR HEART DISEASE
Mitral Valve Disease
Mitral Stenosis
Mitral Regurgitation
Hemodynamics and Secondary Changes
Aortic Valve Disease
Aortic Stenosis
Aortic Regurgitation
Tricupid Valve Disease
Pulmonary Valve Disease
HEART VALVE SUBSTITUTES
Choice of Valve Substitute
Prosthetic Heart Valve Disease
Important Aspects of Follow-up Care of Mechanical Valves
ISCHEMIC HEART DISEASE
Anatomy of the Coronary Arteries
Pathophysiology
Clinical Presentations of Coronary Artery Disease
Investigations
Electrocardiograph
Stress Testing
Coronary Angiography
Medical Management
Indications for Surgery
Historical Aspects of Coronary Revascularization
Conduits used for Bypass Grafting.
Alternative Conduits
Coronary Artery Bypass Grafting (CABG)
Surgical Results
Coronary Reoperations
83:
Neurosurgery
RECENT ADVANCES IN NEUROSURGERY
Gamma Knife Radiosurgery
Deep Brain Stimulation
Neuroendoscopy
Spinal Instrumentation and Implants
Image-guided Surgery
Microsurgery
Epilepsy Surgery
Microvascular Surgery
Equipments Used in a Modern Theater
HEAD INJURY
External Injuries to the Scalp
Fractures of the Vault of Skull
Intracranial Injuries
Effects of Raised Intracranial Pressure
Evaluation of a Patient with Suspected Intracranial Injury
Types of Intracranial Injuries
PERIPHERAL NERVE INJURIES
Causes of Peripheral Nerve Injuries
Cut Injuries
Traction Injuries
Injection Injury
Compression Injuries
Electrical and Thermal Injuries
Diagnosis of Individual Nerve Injuries
Injuries of the Upper Limb
Injuries of the Lower Limb
Management of Peripheral Nerve Injuries
Physiotherapy and Rehabilitation
Brachial Plexus injuries
BRAIN TUMORS
Clinical Features of Brain Tumors
Diagnosis
Pathology
Intra-axial Tumors
Extra-axial Tumors
Man]agement of Brain Tumors
Cerbrovascular Disease
Stroke
Clinical Features
Treatment
Intracranial Aneurysm (Berry Aneurysm)
Clinical Features
Diagnosis
Management
Arteriovenous Malformation
Congenital Abnormalities
Spinal Dysraphism
Cranial Dysraphism
Hydrocephalus
Hydrocephalus in Infants and Children
Clinical Features
Management
Craniosynostosis
INFECTIONS
Subgaleal Abscess
Osteomyelitis
Subdural Empyema
Brain Abscess
Clinical Features
Diagnosis
Treatment
Intracranial Tuberculoma
Epidural Abscess
Meningitis
SECTION 20: MORE THAN SURGERY
84:
Medical Ethics and Medicolegal Aspects of Surgery
MEDICAL CODES AND OATHS
Hippocratic Oath
MEDICAL ETHICS
Doctor-Patient Relationship
Role of the Surgeon
Ethical Practices
Ethical Problems Special to Surgery
Training of Surgeons
Corporate Hospitals and Medical Insurance
Innovation and Newer Techniques
Ethical Issues in Fetal Surgery
Blood Transfusion
Ethics and AIDS
Cosmetic Surgery
Organ Donation
Resuscitation and Do Not Resuscitate (DNR) Orders
Consent to Surgical Treatment
Types of Consent
Medical Negligence
(Increasing) Litigation Against Doctors
Legal Procedure in Case of Negligence
Consumer Protection Act (1986)
Procedure Followed in a Consumer Court
Surgeon as an Expert Witness
Areas where Litigation is common
Retained Foreign Bodies and its Medicolegal Aspect
Other Areas
How to Avoid Medical Litigation?
Teaching of Clinical Ethics
Institutional Reviews of Mistakes in Surgery
Communication
85:
Care of Terminally Ill Patients
INTRODUCTION
PALLIATIVE CARE FOR CANCER PATIENTS
COMMON SYMPTOMS IN ADVANCED CANCER PATIENTS
Pain
General Principles of Pain Management
Management
Monitoring
Anorexia and Cancer Cachexia
Dyspnea
Constipation
Treatment
Effusions
Pleural Effusions
Malignant Ascites
Anxiety and Depression
Confusion
Treatment
Psychiatric Manifestations
Grieving
Stress
Management Strategies
Communicating with the Patient and the Family
Abnormal Grief in Survivors
Financial Concerns of Dying Patients
Managing Death
86:
Instruments, Sutures and Machines
INSTRUMENTS USED IN GENERAL SURGICAL PRACTICE
Instruments used for Preparing and Draping
Instruments for Skin Incision
Instruments for Securing Hemostasis
Retractors
Dissecting Forceps/Thumb Forceps
Tissue Holding Forceps
Scissors
Special Instruments in General Surgery
Bone Instruments Used in General Surgery
MATERIALS FOR TISSUE APPROXIMATION AND WOUND CLOSURE
Suture Material
Absorbable versus Non-absorbable Sutures
Natural versus Synthetic Material
Monofilament versus Polyfilament Sutures
Suture Needles
Sutures used in General Surgical Practice
Modern methods of skin closure/approximation
Staplers in Surgery
Thoracic Anastomosis Instrument
Gastrointestinal Anastomosis Instrument (GIA)
End-to-End Anastomosis (EEA)
Diathermy
Monopolar and Bipolar Diathermy
Cutting and Coagulating Diathermy
Cavitron Ultrasonic Suction Aspirator (CUSA)
Surgical Drains and Tubes
Nasogastric Tubes
Chest Drains
Drain at Operative Site
Malecots Catheter
Suction Drain
Kehr's T-Tube
Pulse Oximeter
Implant Materials
Implant Materials in Orthopedic Surgery
Complications of Implants
Tissue Response to Foreign Material
Tissue Expansion
Ventilators
Classification
87:
Laboratory Values of Clinical Importance
INDEX
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