Special Volume 16
Pediatric Cardiology
- Also by Prof (Dr) Suraj GupteRecent Advances in Pediatrics (RAP): Topical Issues in General/Miscellaneous PediatricsVol 16 (2006), Vol 15 (2005), Vol 14 (2004), Vol 13 (2003), Vol 12 (2002),Vol 11 (2001), Vol 10 (2000), Vol 9 (1999), Vol 8 (1998), Vol 7 (1997),Vol 6 (1996), Vol 5 (1995), Vol 4 (1994), Vol 3 (1993), Vol 2 (1992), Vol 1(1991)
- Recent Advances in Pediatrics (RAP): Special VolumesRAP Special Vol 17 (2006): AdolescenceRAP Special Vol 15 (2005): Pediatric NephrologyRAP Special Vol 14 (2005): Critical Care PediatricsRAP Special Vol 13 (2004): Pediatric EndocrinologyRAP Special Vol 12 (2003): Neonatal EmergenciesRAP Special Vol 11 (2002): Community PediatricsRAP Special Vol 10 (2002): PulmonologyRAP Special Vol 9 (2001): NeurologyRAP Special Vol 8 (2001): Emergency PediatricsRAP Special Vol 7 (2000): HematologyRAP Special Vol 6 (2000): Gastroenterology, Hepatology and NutritionRAP Special Vol 5 (2000): Neonatology-2RAP Special Vol 4 (1999): NeonatologyRAP Special Vol 3 (1999): Tropical Pediatrics-2RAP Special Vol 2 (1998): Tropical PediatricsRAP Special Vol 1 (1997): Nutrition, Growth and Development
- RAP Volumes in Pipeline for 2007
- RAP 17: (General Pediatrics): Topical Issues in General/Miscellaneous Pediatrics
- RAP Special Vol 18: Pediatric Neurology
- RAP Special Vol 19: Difficult Child
- Other Books by Prof (Dr) Suraj Gupte
- The Short Textbook of Pediatrics, 10th (Silver Jubilee) edition
- Differential Diagnosis in Pediatrics, 5th edition
- Instructive Case Studies in Pediatrics, 5th edition
- Pediatric Drug Directory, 8th edition
Special Volume 16
Pediatric Cardiology
Editor Suraj Gupte MD, FIAP Director Children's Health Center Professor and Head (Ex) Pediatric Unit Government Medical College and Associated Hospitals Jammu- 180 001 Jammu and Kashmir, India E-mail:surajgupte@rediffmail.com
Honorary Director Pediatric Education Network
Editor The Short Textbook of Pediatrics, Textbooks of Pediatric Emergencies, Neonatal Emergencies and Pediatric Nutrition, Pediatric Yearbook Series, Pediatric Today Monograph Series, Newer Horizons in Tropical Pediatrics, Towards MRCPCH Part II (Theory) Examination
Author Differential Diagnosis in Pediatrics, Instructive Case Studies in Pediatrics, Pediatric Drug Directory, Infant Feeding, Speaking of Child Care: Everything You Wanted to Know, The Baby Book: The Parents’ Guide from Birth to Infancy
Co-editor Asian Journal of Maternity and Child Health (Manila, Philippines)
Section Editor Pediatrics Today (New Delhi, India)
Editorial Adviser Asian Journal of Pediatric Practice (New Delhi, India)
Editorial Advisory Board Member/Reviewer Indian Journal of Pediatrics (New Delhi, India), Indian Pediatrics, (New Delhi, India)
Synopsis: A Current Survey of World Literature in Pediatrics (Detroit, USA), Indian Journal of Pediatric Gastroenterology, Hepatology and Nutrition (Jaipur, India), Maternal and Child Nutrition (Preston, UK)
Examiner National Board of Examinations (NBE) for DNB, New Delhi, All India Institute of Medical Sciences (AIIMS), New Delhi, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Sher-i-Kashmir Institute of Medical Sciences (SKIMS) and several universities
Pediatric Faculty Selection Expert All India Institute of Medical Sciences, New Delhi Punjab Public Service Commission
Jitendar P Vij
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Recent Advances in Pediatrics (Special Volume 16: Pediatric Cardiology)
© 2006, Shamma-Bakshi Gupte, Executive Editor
All rights reserved. No part of this publication should be reproduced, stored in a retrieval system, or transmitted in any form or by any means: electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the editor and the publisher.
First Edition : 2006
9788180617232
Typeset at JPBMP typesetting unit
Printed at Gopsons
To
The fond memory of our late Parents
whose inspiration, blessings and
moral support continue to contribute
a great deal to our academic
endeavors and
Everybody contributing to child health
and welfare for a better future
7Contributors
- Abdul Hamid A Al-Najjar
- Consultant Pediatric Cardiologist
- Department of Pediatrics
- Madina Maternity and Children Hospital
- Madina, Saudi Arabia
- Ch 10: Coarctation of the Aorta
- Ch 19: Cardiac Arrhythmias
- Jaya Suresh Babu
- Consultant
- Pediatric Critical Unit and Pediatric Cardiology Division
- Department of Child Health
- Sultan Qaboos University Hospital
- Muscat, Sultanate of Oman
- Ch 18: Shock
- B Vishnu Bhat
- Professor
- Department of Pediatrics
- Jawaharlal Institute of Postgraduate Medical Eduction and Research
- Pondicherry 605 006
- India
- Ch 3: Congestive Heart Failure in the Neonates
- Rajiv Chhabra
- Clinical Fellow
- Pediatric Intensive Care Unit (PICU)
- St Mary's Hospital
- London, UK
- Ch 11: Pulmonary Hypertension in Children
- N Chandrakumar
- Senior Resident
- Department of Pediatrics
- Jawaharlal Institute of Postgraduate Medical Eduction and Research
- Pondicherry 605 006
- India
- Ch 3: Congestive Heart Failure in the Neonates
- VP Chaudhry
- Professor
- Department of Hematology
- All India Institute of Medical Sciences
- New Delhi, India.
- Ch 23: Inherited Neonatal Thrombosis
- Akash Deep
- Clinical Fellow
- Pediatric Intensive Care Unit (PICU)
- St Mary's Hospital
- London, UK
- Ch 2: Congestive Cardiac Failure in Children
- Ch 11: Pulmonary Hypertension in Children
- Subodh Ganu
- Senior Resident
- Department of Pediatrics
- Postgraduate Institute of Medical Education and Research
- Chandigarh, India
- Ajay Gaur
- Associate Professor
- GR Medical College
- Gwalior, India
- Ch 13: Pericardial Effusion
- Renuka Gera
- Senior Consultant
- Pediatric and Adolescent Hematology-Onology Department
- Michigan State University
- East Lansing, MI, United States
- Ch 22: Venous Thromboembolism
- Vandana Gopal
- Pediatric Intensivist
- Krishna Critical Child Care Center
- Vadodra, India
- Ch 5: The Newborn with Cyanosis and Tachypnea
- Ch 6: Evaluation of the Child with Congenital Heart Disease
- Sanjeev Gupta
- Senior Resident
- Department of Pediatrics
- Dayanand Medical College and Hospital
- Ludhiana, India
- Ch 7: Tetralogy of Fallot
- M Issaivanam
- Senior Resident (Ex)
- Department of Hematology
- All India Institte of Medical Sciences
- New Delhi, India
- Ch 23: Inherited Neonatal Thrombosis
- B K Jain
- Professor and Head
- Department of Pediatrics
- Dayanand Medical College and Hospital Ludhiana, India
- Ch 8: Transposition of Great Vessels
- Ch 17: Childhood Hypertension
- Manjeet S Juneja
- Associate Consultant
- Institute of Cardiovascular Diseases
- Madras Medical Mission
- Chennai, Tamil Nadu, India
- Ch 15: Infective Endocarditis in Childrens
- Shivani Kansal
- Senior Resident
- Department of Pediatrics
- Dayanand Medical College and Hospital Ludhiana, India
- Ch 7: Tetralogy of Fallot
- Karunakara BP
- Assistant Professor
- Department of Peditrics
- MS Ramaiah Medical College and
- Teaching Hospital
- Bangalore, India
- Ch 14: Constrictive Pericarditis
- Ch 16: Myocarditis
- Arvind Kohli
- Lecturer
- Cardiothoracic and Vascular Surgery Unit
- Department of Surgery
- Government Medical College
- Jammu, India
- Ch 9: Acyanotic Congenital Heart Disease
- Vikas Kohli
- Consultant Interventionist
- in Pediatric Cardiology
- Indraprastha Apollo Hospitals
- New Delhi, India
- Ch 12: Transcatheter Closure of the Atrial
- Sara Sebnem Kilic
- Professor
- Immunology Division
- Department of Pediatrics
- Uludag University Medical School
- Gorukule, Bursa, Turkey
- Ch 20: Takayasu's Arteritis
- Ch 21 : DiGeorge Syndrome
- Roshni Kulkarni
- Consultant
- Pediatric and Adolescent Hematology-Onology Department
- Michigan State University
- East Lansing, MI, United States
- Ch 22: Venous Thromboembolism
- Naveen Kumar
- Senior Resident
- Department of Pediatrics
- Dayanand Medical College and Hospital
- Ludhiana, India
- Ch 17: Childhood Hypertension
- PP Maiya
- Professor and Head
- Department of Pediatrics
- MS Ramaiah Medical College and
- Teaching Hospital
- Bangalore, India
- Ch 14: Constrictive Pericarditis
- Ch 16: Myocarditis
- Bishav Mohan
- Cardiologist
- DMC Cardiology Centre
- Dayanand Medical College and Hospital
- Ludhiana, India
- Ch 17: Childhood Hypertension
- Zenaida Soriano Reyes
- Consultant
- Pediatric Critical Unit
- Department of Child Health
- Sultan Qaboos University Hospital
- Muscat, Sultanate of Oman
- Ch 18: Shock
- Manvinder Singh Sachdev
- Consultant
- Institute of Cardiovascular Diseases
- Madras Medical Mission
- Chennai, India
- Ch 15: Infective Endocarditis
- Khalid M Saidy
- Consultant Neonatologist
- Department of Pediatrics
- Madina Maternity and Children Hospital
- Madina, Saudi Arabia
- Ch 10: Coarctation of Aorta
- Ch 19: Cardiac Arrhythmias
- Anita Saxena
- Professor of Cardiology
- All India Institute of Medical Sciences
- New Delhi, India
- Ch 1: Cardiomyopathy in Children
- Ashwani Singal
- Assistant Professor
- Department of Pediatrics
- Dayanand Medical College and Hospital
- Ludhiana, India
- Ch 8: Transposition of Great Vessels
- Harmesh Singh
- Reader
- Department of Pediatrics
- Dayanand Medical College and Hospital
- Ludhiana, India
- Mukesh Kumar Singh
- Assistant Professor
- Department of Pediatrics
- Medical College
- Vadodra, India
- Ch 5: The Newborn with Cyanosis and Tachypnea
- Ch 6: Evaluation of the Child with Congenital Heart Disease
- Nanjunda Swamy
- Associate Professor
- Department of Pediatrics
- MS Ramaiah Medical College and Teaching Hospital
- Bangalore, India
- Ch 14: Constrictive Pericarditis
- Poothirikovil Venugopalan
- Consuktant Pediatric Cardiologist
- Department of Child Health
- Sultan Qaboos University Hospital
- Muscat, Sultanate of Oman
- Ch 18: Shock
- Victor Yu
- Professor of Neonatology
- Clinical Director
- Ritchie Center for Baby Health Research
- Monash Medical Centre
- Monash University
- Melbourne, Victoria, Australia
- Ch 4: Persistent Pulmonary Hypertension of the Newborn
With the availability of sophisticated investigative and therapeutic know-how and technological advances in increasing number of centers, pediatric cardiology in India and other developing countries is beginning to gear up for new challenges. As a result, the need to sensitize and involve the pediatricians (both in institutions and field practice) to these advances in relation to specific cardiac disease entities over and above the general principles of congenital and acquired heart disease is being increasingly felt.
In the light of this background, the 16th Special volume of the noted international series, Recent Advances in Pediatrics, first launched in 1991 and now concurrently in the 16th Annual and 17th special volumes (RAP 16 and RAP Special Vol 17: Adolescence, respectively), offers deliberations on key topical issues in the field of pediatric cardiology.
The 23 state-of-the-art chapters covered by as many as 31 experts drawn from India and abroad attempt to review the depth and breadth of knowledge in the field of pediatric cardiology with special reference to its applicability in the Indian subcontinent. The objective is to provide authentic knowledge and infomation for the general pediatricians in particular so that they become well equipped to provide good care to their cardiac subjects and take appropriate decisions for referral to the superspecialist in certain unavoidable situations.
Each and every chapter is remarkable by its excellence, providing a stimulating and, not infrequently, even provocative, matured and informed update. Understandably, such an approach is befitting when the goal is not only to inform but also to motivate discussion, interaction, research and innovation.
In keeping with the professed policy of the series, multidisciplinary approach with an eye on future continues to occupy pride of place in this volume too.
We appreciate the distinguished role of the eminent pediatric cardiologist, Dr Anita Saxena, Professor of Cardiology, All India Institute of Medical Sciences, as the Guest Editor as well as contributor of an excellent chapter for this special volume.
We wish to record our indebtedness to our distinguished contributors for providing excellent state-of-the-art chapters in various aspects of pediatric cardiology and related topics. They were also gracious enough to repose confidence in our editorship. Without their understanding and cooperation, this volume wouldn't have seen the light of the day.
Thanks are also due to the Advisory Editorial Board for providing inputs and advice in various editorial matters and peer reviewers for 12not only providing us the benefit of their critical expertise but also for the promptness in responding to our requests for speedy action.
Our daughter, Novy, a final year MBBS student, Government Medical College, Jammu, and son, Manu, an 8th semester student of Bachelor of Engineering, MBS College of Engineering and Technology, Jammu, voluntarily provided all sorts of assistance in taking the project to its logical conclusion.
M/s Jaypee Brothers Medical Publishers (P) Ltd, New Delhi and their dedicated staff deserve our special gratitudes for the speedy work in completing this project and its skillful production qualities.
Suraj Gupte
Academic Editor
Shamma-Bakshi Gupte
Executive Editor
E-mail: surajgupte@rediffmail.com
13Guest Editor's Introductory Note
It is my proud privilege and honor to serve as the Guest Editor for this Special Volume on Pediatric Cardiology of the noted series, Recent Advances in Pediatrics edited by Prof Suraj Gupte.
The subspecialty of pediatric cardiology has witnessed tremendous growth and expansion over the last six decades. Admittedly, it is not possible to cover details of each disease. The main thrust of this book is, therefore, to educate the practising pediatricians regarding the general issues of congenital and acquired heart diseases as relevant in our country and to introduce the advances made recently in this subspecialty.
In this book, congenital heart diseases have been covered in seven chapters, starting with the approach to a newborn with cyanosis to a common clinical scenario faced by the pediatrician. Some of the common congenital heart diseases like tetralogy of Fallot, transposition of great vessels and coarctation of aorta have been discussed in detail.
A large part of the book is dedicated to acquired cardiac disorders in children. The topics covered include myocarditis, cardiomyopathy, infective endocarditis, pericarditis, Takayasu's arteritis, thrombo-embolism, etc. Hypertension in children, a common but often unrecognized problem has also been well discussed in the Chapter on “Childhood Hypertension.” Similarly, another important topic very nicely covered is that of “Cardiac Arrhythmias.” Common rhythm disorders as seen in children are well discussed in details and their management outlined.
The book also deals with common cardiac emergencies like shock and congestive heart failure. There is a fine article covering current thoughts in management of persistent pulmonary hypertension of the newborn.
Although recent advances have been outlined in each chapter, a separate chapter is devoted to the transcatheter treatment for closure of septal defects like atrial septal defect, ventricular septal defect, patent ductus arteriosus, etc. This is a very exciting field for interventional cardiologist as well as the patient, as the defects are closed without resorting to surgery.
In summary, the Recent Advances in Pediatrics (Special Vol 16: Pediatric Cardiology) incorporates topics which have an immense educational value for a practising pediatrician. Hopefully, these discussions would provide a fund of information for better cardiac care of the “little patients” and the well-conceived and well-executed book shall prove a considerable value for the target readership.
Anita Saxena
Professor of Cardiology
All India Institute of Medical Sciences (AIIMS)
New Delhi, India