Oral and perioral lesions are common in patients with HIV infection. JJ Pindborg et al in 1989 documented the revised edition of oral lesions associated with HIV infection. In 1989 WHO collaborative center and EC clearing house of oral problems had given some diagnostic criteria of oral manifestations in HIV infected patients. Scualy C, George Laskaris et al in 1991 documented oral disorders in HIV diseases as which were more common and less common in HIV patients. DM Williams in 1993 in his article “classification and diagnostic criteria for oral lesions in HIV infection” mentioned about the consensus that was reached on the classification of oral manifestations of HIV infection and their diagnostic criteria. Revised classification of oral lesions associated with HIV infection was given as agreed at a meeting of the EC Clearing house on oral problems related with HIV infection in 1992. Robinson et al in 1994 suggested certain diagnostic criteria to diagnose HIV associated periodontitis. In 1995 Ficarra G listed out several etiological agents for oral ulcers in HIV infected individuals. Deepak Kademi and Michel Click in 1998 showed different etiology and conditions associated with oral liberation in HIV infected. Eversole LR in 1992 stated that many viruses cause opportunistic infections in HIV positive patients. Schiodt M in 1992 stated that a number of lesions affecting the salivary gland were noted in HIV infected patients. Epstein Joel B and Silverman Sol. Jr. stated that immunosuppressed persons have an increased risk of developing various malignancies of head and neck region. Altered pigmentation of the skin, nail and mucous membranes has been observed in HIV infected patients.