Ultrasound Imaging of Fetal Anomalies Kuldeep Singh
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HEAD AND BRAIN (NORMAL ANATOMY)CHAPTER 1

  • ▸▸ BASICS
  • ▸▸ CRANIAL BIOMETRY
  • ▸▸ VENTRICULAR ATRIUM
  • ▸▸ CEREBELLUM
  • ▸▸ CISTERNA MAGNA
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BASICS
  • In the late first trimester ultrasound the cranial vault, brain tissue and lateral ventricles occupied by the choroid plexuses can be visualized.
  • In the anomaly scan done between 18–22 weeks of gestation the ventricular system, subarachnoid space, the diencephalic and rhombencephalic structures can be evaluated in detail.
  • Visualization of the ventricular atrium, the cisterna magna and the cavum septum pellucidum on the standard imaging planes excludes most of the cranial anomalies.
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Fig. 1.1: Section for cranial biometry consisting of the thalamus, the third ventricle and the cavum septum pellucidum. The biparietal diameter is the side to side measurement from the outer table of the proximal skull to the inner table of the distal skull. The head perimeter is the the total cranial circumference, which includes the maximum anteroposterior diameter. The occipito-frontal diameter is the front to back measurement from the outer table on both sides
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Fig. 1.2: The thalamus and cavum septum pellucidum seen in the section for cranial biometry
  • Meticulous cranial biometry consisting of the biparietal diameter, head perimeter, occipito-frontal diameter, ventricular width, interhemispheric distance, cerebellar transverse diameter and depth of cisterna magna is essential as this can help in diagnosing many anomalies.
 
CRANIAL BIOMETRY (TRANSTHALAMIC VIEW)
  • Section for cranial biometry consists of the thalamus, the third ventricle and the cavum septum pellucidum (Figs 1.1 and 1.2).
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  • Biparietal diameter: Side to side measurement from the outer table of the proximal skull to the inner table of the distal skull.
  • Head perimeter: The total cranial circumference, which includes the maximum antero-posterior diameter.
  • Occipito-frontal diameter: Front to back measurement from the outer table on both sides.
 
VENTRICULAR ATRIUM (TRANSVENTRICULAR VIEW)
  • The choroid plexus should occupy the whole of the body of the lateral ventricle (Figs 1.3 to 1.5).
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Fig. 1.3: Choroid plexus (CP) seen occupying the whole of the body of the lateral ventricle (LV). The anterior horn of the lateral ventricle (solid line) seen on the left side and posterior horn of the lateral ventricle (dashed line) seen on the right side are not filled by the choroid plexus
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Fig. 1.4: Choroid plexus seen in the lateral ventricles on both sides
  • Upper limit of normal being 10 mm.
  • The width of the body, anterior horn and posterior horn of the lateral ventricle are taken. (Normal value < 08 mm, borderline 08–10 mm and > 10 mm abnormal) (Fig. 1.6).
  • The lateral ventricle/interhemispheric width ratio is not very sensitive for early dilatation so is not used very often for defining hydrocephalus (Fig. 1.6).
  • When the choroid plexus does not occupy the whole of the body of the lateral ventricle see for the measurement of the medial separation of the choroid plexus from the wall of the lateral ventricle. (Normal value < 02 mm, Borderline 02–03 mm and > 03 mm is abnormal) (Fig. 1.7).
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Fig. 1.5: The choroid plexus quite often does not occupy the whole of the body of the lateral ventricle and the frontal and the posterior horn also are not filled by the choroid plexus (stars)
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Fig. 1.6: The width of the body of the lateral ventricle, the interhemispheric distance and the ratio of the width of the body of the lateral ventricle to the interhemispheric distance is calculated. (Normal value < 50%). This is not sensitive for early hydrocephalus. The width of the body, anterior horn and posterior horn of the lateral ventricle are taken (Normal value < 08 mm, borderline 08–10 mm and > 10 mm abnormal)
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Fig. 1.7: When the choroid plexus does not occupy the whole of the body of the lateral ventricle see for the measurement of the medial separation (arrow) of the choroid plexus from the wall of the lateral ventricle (Normal value < 02 mm, borderline 02–03 mm and > 03 mm is abnormal)
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CEREBELLUM (TRANSCEREBELLAR VIEW)
  • The cerebellum is seen as a ‘W’ turned 90 degrees (Fig. 1.8).
  • Measure cerebellar transverse diameter.
  • The cerebellar transverse diameter (CTD) is measured from the edges of both cerebellar hemispheres. The CTD in mm from 14–22 weeks is equal to the gestational age of the fetus in weeks (Fig. 1.9).
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Fig. 1.8: The cerebellum is seen as a ‘W’ turned 90 degrees. The cerebellar hemispheres (C) and the cerebellar vermis (within the circle) should be appreciated for posterior cranial fossa abnormalities
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Fig. 1.9: The cerebellar transverse diameter (CTD) is measured from the edges of both cerebellar hemispheres. The CTD in mm from 14–22 weeks is equal to the gestational age of the fetus in weeks
  • Look for any hypoplasia of the superior and inferior cerebellar vermis.
  • Whether there is any communication between fourth ventricle and cisterna magna.
 
CISTERNA MAGNA
  • The cisterna magna is seen posterior to the cerebellar vermis and anterior to the occipital bone (Fig. 1.10).
  • (Normal value < 08 mm, borderline 08–10 mm and > 10 mm abnormal).
  • Should not be more than 10 mm.
  • Few strands seen traversing the cisterna magna are normal.
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Fig. 1.10: The cisterna magna is seen posterior to the cerebellar vermis and anterior to the occipital bone (solid line) (Normal value < 08 mm, borderline 08–10 mm and > 10 mm abnormal). Few strands seen traversing the cisterna magna are normal. Carefully check for any communication between the fourth ventricle and the cisterna magna with an abnormal cerebellar vermis. If there is any communication at gestational age less than 16 weeks revaluate the fetus after 2 weeks
  • Carefully check for any communication between the fourth ventricle and the cisterna magna through an abnormal cerebellar vermis. If there is any communication at gestational age less than 16 weeks revaluate the fetus after 2 weeks.
  • Check for any posterior fossa cyst.