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Oral Medicine
Satish Chandra, Shaleen Chandra, Girish Chandra, Kamala R
1:
Introduction, Scope and Role of Oral Medicine in Dental Practice
DEFINITION
INTRODUCTION
SCOPE
ORAL MEDICINE IN HOSPITAL PRACTICE
MANAGEMENT OF DENTAL PATIENTS HAVING SEVERE MEDICAL PROBLEMS
2:
Evaluation of Patient and Psychology
DOCTOR-PATIENT RELATIONSHIP
PSYCHOSOMATIC ORAL DISEASES
ORAL AND DENTAL MANIFESTATIONS OF ANXIETY
Faulty Oral Behavioral Patterns
Effect on Autonomic Nervous System
Relationship of Pain and Anxiety
PSYCHOLOGICAL CONSIDERATIONS IN DENTAL TREATMENT
3:
Oral Physiology, Anatomy and Histology Related to Oral Medicine
SALIVA
Composition of Saliva
Role of Saliva in Oral Health
ORAL MUCOUS MEMBRANE
Histology of Mucous Membrane
GINGIVA
Histology of Gingiva
Epithelium
Connective Tissue
PERIODONTIUM
Fibrous Tissues
Mineralized Tissues
Periodontal Ligament
PULP
Structure of the Pulp
Odontoblastic Zone
Cell-free zone
Cell-rich zone
Central Zone
MICROBIAL FLORA OF ORAL CAVITY
Indigenous Flora
Transient Flora
Factors which Influence Growth of Microorganisms
Microorganisms Present in Oral Cavity
Bacteria
Fungi
Protozoa
DEPOSITS ON TEETH
Materia Alba
Dental Plaque
Calculus
4:
Nutrition and Oral Diseases
CARBOHYDRATES
Monosaccharides
Disaccharides
Polysaccharides
Functions of Carbohydrates
Role of Carbohydrates in Dental Caries
ROLE OF FATS IN ORODENTAL HEALTH
RELATIONSHIP OF PROTEINS WITH ORAL HEALTH AND DISEASE
VITAMINS AND THEIR ORAL MANIFESTATIONS
Fat-soluble Vitamin
Vitamin A
Vitamin D
Vitamin E
Vitamin K
Water Soluble Vitamins
Vitamin B Complex
Vitamin C (Ascorbic Acid)
MINERALS AND TRACE ELEMENTS
Calcium
Phosphorus
Magnesium
Iodine
Iron
Fluoride
5:
Pathology Related to Oral Medicine
INFLAMMATION
Signs of Inflammation
Swelling
Heat
Redness
Pain
Loss of Function
Types of Inflammation
Acute Inflammation
Chronic Inflammation
Subacute Inflammation
Chronic Granulomatous Inflammation
Acute Inflammation
Changes in Vascular Calibre and Flow
Increased Vascular Permeability
Emigration of Leukocytes
Phagocytosis
Chronic Inflammation
Characteristics of Chronic Inflammation
HYPERTROPHY
Physiologic Hypertrophy
Compensatory Hypertrophy
Pathologic Hypertrophy
HYPERPLASIA
Physiologic Hyperplasia
Pathologic Hyperplasia
Compensatory Hyperplasia
INFECTION
Factors in Relation to Microorganisms
Route of Entry
Spread of Infection
Production of Toxins
Factors Relating to Host
Barrier Against Invasion
Immune Defence Mechanisms
SHOCK
Primary Shock
Secondary Shock
Etiology and Types of Shock
Biochemical Mechanism of Shock
HEALING OF ORAL WOUND
Factors Affecting the Healing of Oral Wounds
Site of Wound
Movement of Wound Area
Temperature
Nutritional Factors
Age of Patient
Infection
6:
Oral Examination and Diagnosis
INTRODUCTION
PROCEDURE OF ORAL DIAGNOSIS
1. History Taking and Recording
Constituents of Patient History
2. Examination of the Patient
General Examination
Examination of Head, Neck and Oral Cavity
Extraoral Examination
Intraoral Examination
3. Specialized Examination Procedures and Laboratory Investigations
Laboratory Investigations
4. Establishing the Diagnosis
5. Treatment Planning
7:
Developmental Disorders Affecting Oral and Para Oral Structures
DEVELOPMENTAL DISORDERS OF THE TEETH
Disorders in Size of Teeth
Microdontia
Macrodontia
Disorders in Number of Teeth
Anodontia
Supernumerary Teeth
Accessory Teeth
Predeciduous Teeth
Disorders in Shape of Teeth
Fusion
Concrescence
Gemination
Dilaceration
Dens Evaginatus
Dens-in-Dente (Dens Invaginatus; Dilated Composite Odontome)
Taurodontism
Disorders in Structure of Teeth
Amelogenesis Imperfecta
Dentinogenesis Imperfecta
Enamel Hypoplasia
Dentinal Dysplasia
Regional Odontodysplasia
Periapical Cementoma
Disorders in Tooth Eruption
Premature Eruption
Delayed Eruption
Ectopic, Impacted and Embedded Teeth
Cross Bite
Deep Overbite
Diastema
DEVELOPMENTAL DISORDERS OF THE JAWS
Agnathia
Micrognathia
Macrognathia
Facial Hemiatrophy
Facial Hemihypertrophy
DEVELOPMENTAL DISORDERS OF THE TONGUE
Microglossia
Macroglossia
Ankyloglossia (Tongue Tie)
Median Rhomboid Glossitis
Fissured or Scrotal Tongue
Cleft or Bifid Tongue
Lingual Thyroid Nodule
DEVELOPMENTAL DISORDERS OF LIPS AND PALATE
Cleft Palate
Cleft Lip
Congenital Lip Pits
Double Lip
Cheilitis Glandularis
Torus Palatinus
DEVELOPMENTAL DISORDERS OF THE ORAL MUCOSA
Fordyce's Granules (Spots)
White Sponge Nevus
Focal Epithelial Hyperplasia
Peutz-Jegher's Syndrome (Hereditary Intestinal Polyposis with Melanin Syndrome)
Epidermolysis Bullosa Dystrophica
Fibromatosis Gingivae (Hereditary Gingival Fibromatosis, Elephantosis Gingivae, Congenital Macrogingival)
Treatment
8:
Diseases of Teeth and Supporting Tissues
DENTAL CARIES
Etiology of Dental Caries
Types and Classification of Dental Caries
Pit and Fissure Caries
Smooth Surface Caries (Proximal Caries)
Root Caries (Senile Caries)
Rampant Caries
Nursing Bottle Rampant Caries
Recurrent Caries
Arrested Caries
Chronic Caries
Radiation Caries
DISCOLORATION OF TEETH
Extrinsic Discoloration
Intrinsic Discoloration
Local Causes
Systemic Causes
Drug Induced
Common Internal Discolorations
Treatment of Discolored Tooth
ABRASION OF THE TEETH
Etiology of Abrasion
ATTRITION OF THE TEETH
EROSION OF THE TEETH
Abfraction
GINGIVITIS AND GINGIVAL ABSCESS
Etiological Factors
Local Factors
Systemic Factors
Clinical Features
Treatment
GINGIVAL ENLARGEMENT
Inflammatory Gingival Enlargement
Fibrotic Gingival Enlargement (Drug-induced)
Gingival Enlargement Associated with Systemic Conditions
Enlargement in Pregnancy
Enlargement in Puberty (Puberty Gingivitis)
Enlargement in Nutritional Deficiency
PERIODONTITIS
Treatment
JUVENILE PERIODONTITIS
Treatment
9:
Diseases of the Pulp and Periapical Tissues
INTRODUCTION
ETIOLOGY OF PULP DISEASES
DISEASES OF THE PULP
Reversible Pulpitis (Pulpal Arterial Hyperemia)
Acute Irreversible Pulpitis
Clinical Features
Treatment
Chronic Pulpitis
Chronic Hyperplastic Pulpitis (Pulp Polyp)
Clinical Features
Treatment
Necrosis of the Pulp
Internal Resorption
Clinical Features
Treatment
Pulp Calcification
True Pulp Stones (Denticles)
False Pulp Stones (Denticles)
Diffuse Calcification
Etiology
Clinical Significance
DISEASES OF PERIAPICAL TISSUES
Acute Apical Periodontitis
Clinical Features
Treatment
Periapical Abscess
Clinical Features
Treatment
Alveolar Abscess
Clinical Features
Treatment
Periapical Granuloma
Clinical Features
Treatment
Radicular Cyst (Periapical Cyst)
Clinical Features
Treatment
External Root Resorption
Etiology
Clinical Features
Treatment
DISEASES OF PERIODONTAL TISSUES
Periodontal Abscess
Clinical Features
Treatment
Gingival Abscess
Treatment
10:
Ulcerative and Vesiculobullous Lesions of the Oral Cavity
INTRODUCTION
ACUTE MULTIPLE LESIONS (ULCERS AND BLISTERS)
Herpes Virus Infection
Herpes Simplex Virus (HSV) Infection
Primary Herpes Simplex Virus Infection
Varicella-Zoster Virus Infection
Clinical Features
Treatment
Coxsackievirus Infections
Herpangina
Treatment
Acute Lymphonodular Pharyngitis
Hand-Foot-and-Mouth Disease
Contact Allergic Stomatitis
Clinical Features
Treatment
Erythema Multiforme (EM)
Clinical Features
Treatment
Acute Necrotising Ulcerative Gingivitis (ANUG)
Clinical Features
ORAL ULCERS SECONDARY TO CANCER CHEMOTHERAPY
CHRONIC MULTIPLE LESIONS (BLISTERS AND ULCERS)
Pemphigus
Pemphigus vulgaris (PV)
Pemphigus Vegetans
Benign Mucous Membrane Pemphigoid (MMP) or Cicatricial Pemphigoid
Bullous Pemphigoid (BP) or Parapemphigus
Erosive and Bullous Lichen Planus
RECURRENT ORAL ULCERS: RECURRENT HERPES SIMPLEX VIRUS INFECTION
Clinical Features
Treatment
RECURRENT APHTHOUS STOMATITIS (RAS)
Clinical Features
Minor Aphthous Ulcers
Major Aphthous Ulcers
Herpetiform Ulcers
Treatment
BEHCET'S SYNDROME
Clinical Features
Treatment
Herpes Simplex Virus in Immunosuppressed Patients
Oral Manifestations
Treatment
SINGLE ULCERS: TRAUMATIC ULCERS
FUNGAL ULCERS
Histoplasmosis (Darling's Disease)
Blastomycosis
Mucormycosis (Phycomycosis)
Oral Manifestations
Treatment
11:
Red and White Lesions of the Oral Mucosa
RED LESIONS
WHITE LESIONS
ALTERATION IN APPEARANCE AND STRUCTURE OF ORAL MUCOSA
ORAL CANDIDIASIS
NON-KERATOTIC WHITE LESION
KERATOTIC LESIONS WITHOUT PRECANCEROUS POTENTIAL
RED AND WHITE LESIONS WITH PREMALIGNANT POTENTIAL
ALTERATIONS IN APPEARANCE AND STRUCTURE OF NORMAL ORAL MUCOSA
Leukoedema
Linea Alba
Fordyce's Granules
Frictional (Traumatic) Keratinization or Frictional Keratosis (FK)
Lip, Tongue and Cheek Biting
Hereditary Benign Intraepithelial Dyskeratosis (HBID) (Witkop's Disease)
Oral Candidiasis
Acute Candidiasis
Acute Pseudomembranous Candidiasis (Thrush, Moniliasis)
Acute Atrophic Candidiasis
CHRONIC CANDIDIASIS
Chronic Atrophic Candidiasis
Denture Sore Mouth
Angular Cheilitis
Chronic Hyperplastic Candidiasis
Candidiasis Endocrinopathy Syndrome
Treatment of Oral Candidiasis
NON-KERATOTIC WHITE LESIONS
Burns of Oral Mucosa
Habitual Lip and Cheek Biting
Uremic Stomatitis
Non-keratotic White Lesion by Infectious Agents like Koplik's Spot
Syphilitic Mucous Patch
Treatment of Non-keratotic White Lesions
KERATOTIC LESIONS WITHOUT PRECANCEROUS POTENTIAL
Traumatic Keratosis
Focal Epithelial Hyperplasia
Intraoral Skin Grafts
Lesions Associated with Dental Restorations
Psoriasiform Lesions
Keratosis Follicularis
RED AND WHITE LESIONS WITH PREMALIGNANT POTENTIAL
Stomatitis Nicotina Palati
Erythroplakia (Erythroplasia of Queyrat)
Clinical Features
Treatment
Leukoplakia
Etiology
Clinical Features
Malignant Transformation
Classification and Staging of Oral Leukoplakia
Clinical (provisional) diagnosis:
Treatment
Lichen Planus
Etiology
Clinical Features
Treatment
Malignant Potential
Oral Submucous Fibrosis (OSMF)
Etiology
Clinical Features
Management of OSMF
ORAL MANAGEMENT
LOCAL APPLICATION
Lesions Associated with Smokeless Tobacco and Alcohol Use
Oral Lesions Associated with Reverse Smoking
Lupus Erythematosus (Systemic and Discoid)
Discoid Lupus Erythematosus (DLE)
Histopathologic Characteristics
Malignancy Potential
Developmental White Lesions: Ectopic Lymphoid Tissue
Dyskeratosis Congenita
Treatment
12:
Pigmented Lesions of the Oral Tissues
INTRODUCTION
BROWN MELANOTIC LESIONS
Oral Melanotic Macule (Ephelis, Focal Melanosis, Solitary Labial Lentigo)
Drug-induced Melanosis
Malignant Melanoma
Normal Racial or Physiological Pigmentation
Smoker's Melanosis
Nevocellular and Blue Nevi
Endocrinopathic Pigmentation
Neurofibromatosis
Peutz-Jeghers Syndrome
HIV-Oral Melanosis
Albright's Syndrome or Café-au-lait Pigmentation
Pigmented Lichen Planus
BROWN HEME-ASSOCIATED LESIONS
Petechiae
Ecchymosis
Hemochromatosis
BLUE/PURPLE VASCULAR LESIONS
Kaposi's Sarcoma
Hemangioma
Sturge-Weber Syndrome (Disease) (Encephalotrigeminal Angiomatosis)
Varices
Hereditary Hemorrhagic Telangiectasia
Angiosarcoma
GREY/BLACK PIGMENTATIONS
Heavy Metal Ingestion
Lead
Mercury
Bismuth
Silver
Amalgam Tattoo
Graphite Tattoo
Hairy Tongue
MISCELLANEOUS CONDITIONS
Carotenemia
Bilirubin Pigmentation
13:
Benign Oral Tumors
INTRODUCTION
NORMAL STRUCTURAL VARIATIONS
Tori
Ectopic Lymphoid Nodules
INFLAMMATORY (REACTIVE) HYPERPLASIAS
Fibrous Inflammatory Hyperplasia
Oral Squamous Papilloma
Fibroma
Epulis Fissuratum
Pulp Polyp
Pyogenic Granuloma
Pseudoepitheliomatous Hyperplasia
Peripheral and Central Giant Cell Granuloma
Palatal Papillomatosis (Palatal Papillary Hyperplasia)
Benign Lymphoid Hyperplasia
HAMARTOMAS
Hemangioma
Lymphangioma
Granular Cell Tumor
Neurofibroma
Neurilemmoma (Schwannomas; Neuro-Lemmoma; Perineural Fibroblastoma; Neurinoma; Lemmoma)
Melanoameloblastoma
Dermoid/Epidermoid/Sebaceous Cyst
Clinical Features
Treatment and Prognosis
Fibrous Dysplasia of Bone
Ossifying Fibroma
ANEURYSMAL BONE CYST, TRAUMATIC BONE CYST AND STATIC BONE CYST
Teratomas and Dermoid Cysts
Cherubism
BENIGN ODONTOGENIC TUMORS
Tumors of Ectodermal Origin
Ameloblastoma
Adenomatoid Odontogenic Tumor (AOT)
Calcifying Odontogenic Cyst (Gorlin Cyst, Keratinizing and or Calcifying Epithelial Odontogenic Cyst; Cystic Keratinizing Tumor)
Calcifying Epithelial Odontogenic Tumor (Pindborg Tumor)
Squamous Odontogenic Tumor
Tumors of Mesodermal Origin
Cementoma
Odontogenic Myxoma
Central Odontogenic Fibroma
Tumors of Mixed Origin
Ameloblastic Fibroma
Ameloblastic Fibro-odontoma
Odontomas
CYSTS OF THE JAWS
“VIRUS INDUCED” BENIGN TUMORS
Oral Squamous Papilloma
Treatment
Molluscum Contagiosum
Condyloma Acuminatum (Verruca Acuminata; Venereal Wart)
Keratoacanthoma (Self Healing Carcinoma, Molluscum Sebaceum; Verrucoma; Molluscum Pseudocarcinomatosum)
GRANULOMATOUS LESIONS OF THE ORAL CAVITY
Cervicofacial Actinomycosis
ANTIFUNGAL DRUGS
Systemic
Topical
Leprosy (Hansen's Disease)
Syndromes Associated with Benign Oral Tumors
Gardner's Syndrome
Nevoid Basal Cell Carcinoma Syndrome
Multiple Mucosal Neuroma Syndrome (Multiple Endocrine Neoplasia Type III)
Acanthosis Nigricans
Tuberculous Sclerosis
Xanthomas
Cowden's Syndrome
Langerhan's Cell Granulomatosis
Amyloidosis
Von Recklinghausen's Neurofibromatosis
Peutz-Jeghers Syndrome
Albright's Syndrome
Paget's Disease of Bone (Osteitis Deformans)
14:
Malignant Oral Tumors
INTRODUCTION AND EPIDEMIOLOGY
ETIOLOGY AND RISK FACTORS OF ORAL CANCER
CLINICAL FEATURES
SQUAMOUS CELL CARCINOMA (SCC) OF LOWER RIGHT SIDE OF LIP, INCLUDING ANGLE OF MOUTH
VERRUCOUS CARCINOMA OF UPPER LIP
PATHOGENESIS
Mild Dysplasia
Moderate Dysplasia
Severe Dysplasia
INVESTIGATIONS
Imaging
Cytologic Examination
DIFFERENTIAL DIAGNOSIS
DIAGNOSIS OF ORAL CANCER
Types of Diagnostic Tools
EXFOLIATIVE CYTOLOGY
TOLUIDINE BLUE STAINING
PROCEDURE
Advantages
Disadvantage
BIOPSY
EXCISIONAL BIOPSY INDICATIONS
BRUSH BIOPSY
ORAL CDX BRUSH BIOPSY PROCEDURE
INTERPRETATION
CHEMILUMINESCENCE AND LED
Advantages
Principles
Procedure
IMMUNOHISTOCHEMICAL TECHNIQUES
LASERS
Histological Diagnosis of Carcinoma
Carcinoma in Situ
Bowen's Disease
Treatment
Carcinoma
Prediction of Malignancy—Molecular Changes in Premalignancy and Oral Malignancy
PROGNOSIS
TNM Staging of Tumor of Oral Cavity
Virus in Oral Cancer
Tumor Biology
Spread
Nutritional Prevention of Oral Cancer
Signs and Symptoms
TREATMENT OF ORAL CANCER
Surgery
Laser Surgery
Radiation Therapy
Radiation Sources
Treatment Planning
Radiation Dose
Chemotherapy
Anti Cancer Drugs
HORMONES
Act by Altering Hormonal Milieu
GENERAL PRINCIPLES IN CHEMOTHERAPY OF CANCER
Combined Surgical and Radiation Therapy
OTHER HEAD AND NECK CANCERS
Malignant Neoplasm of Salivary Glands
Nasopharyngeal Carcinoma
Basal Cell Carcinoma
Malignant Melanoma
Kaposi's Sarcoma (KS)
Treatment
PRETREATMENT DENTAL AND ORAL EVALUATION
COMPLICATIONS OF CANCER TREATMENT
Mucositis
Xerostomia
Radiation Caries
Osteoradionecrosis
Nutrition
Dentofacial Abnormalities
15:
Diseases of the Tongue
STRUCTURE OF THE TONGUE
FUNCTIONS OF THE TONGUE
Ingestion
Suckling
Swallowing
Respiration
Perception
Jaw Development
Phonation
EXAMINATION OF THE TONGUE
Routine Examination
Specialized Examination Procedures
Cine Radiography
Isotopic Scanning Techniques
Doppler Ultrasound
Real-time Ultrasound
Magnetic Resonance Imaging
Electromyography
DISEASES OF MUCOSA OF THE TONGUE
Changes in Tongue Papillae
Coated or Hairy Tongue
Geographic Tongue (Benign Migratory Glossitis)
Loss and Atrophy of the Tongue Papillae
Nutritional Deficiencies and Hematologic Disorders
Median Rhomboid Glossitis
Ulcerations and Traumatic Injuries on Tongue
Superficial Vascular Changes
Lingual Varicosity
Petechial Hemorrhages
Syphilitic Interstitial Glossitis
DISEASES OF BODY OF THE TONGUE
Infections
Ludwig's Angina
Actinomycosis of Tongue
Cysticercosis and Trichinosis
Amyloidosis of the Tongue
Angioneurotic Edema
Neuromuscular Disorders
Oropharyngeal Dysphagia
Tardive Dyskinesia
Dystonia
Weakness of the Tongue
Myasthenia Gravis
Vascular Disease of Body of Tongue
SQUAMOUS CELL CARCINOMA OF THE TONGUE
Etiological Factors
Clinical Features
Treatment
MISCELLANEOUS
Smoker's Glossitis
Fissured Tongue (Scrotal Tongue)
Hyperplastic Foliate Papillae of Tongue with Midline Fissure
16:
Diseases of Salivary Gland
DIAGNOSIS OF ENLARGED SALIVARY GLAND OR SALIVARY MASS
Physical Examination of Salivary Glands
Parotid Gland
Submandibular and Sublingual Glands
Minor Salivary Glands
Differential Diagnosis
DIAGNOSTIC PROCEDURES IN DRY MOUTH (XEROSTOMIA) EVALUATION
Medical History-Past and Present
EXAMINATION
Collection of Saliva Sample
Whole Saliva
Saliva from Individual Gland
IMAGING OF SALIVARY GLANDS
Plain Film Radiography
Sialography
Indications
Contraindications
Contrast Media (CM)
Disadvantages
Ultrasonography
Indications
Advantages
Disadvantages
Radionuclide Salivary Imaging (RSI), (Scintigraphy)
Indication of Radionuclide Salivary Imaging (RSI), (Scintigraphy)
Advantages of RSI (Scintigraphy)
Disadvantages of RSI (Scintigraphy)
Computed Tomography (CT)
Indications of CT
Advantages of CT
Disadvantages of CT
Magnetic Resonance Imaging (MRI)
Indications of MRI
Advantages of MRI
Disadvantage of MRI
Biopsy of Salivary Glands
Major Glands
Minor Glands
Serological Assessment
Fine Needle Aspiration Biopsy (FNAB)
Open Surgical Biopsy
Imaging
STAGING
SPECIFIC DISEASES AND DISORDERS
Developmental Disorders
Ectopic Salivary Gland
Agenesis, Aplasia and Atresia
Diverticuli
Accessory Ducts
Darier's Disease
FUNCTIONAL DISORDERS
Sialorrhea (Increased Saliva Secretion)
Decreased or Arrested Saliva Secretion (Xerostomia)
RADIATION INDUCED PATHOLOGY
Effects of External Beam Radiation
Clinical Features
Treatment
Dose
Side Effects
Effects of Internal Radiation Therapy
Treatment
Management of Xerostomia
Preventive
Symptomatic
Local Salivary Stimulation
Systemic
OBSTRUCTIVE DISORDERS
Mucocele
Mucous Retention Cyst
Mucous Extravasation Cyst
Sialolithiasis (Salivary Gland Stones)
Clinical Features
Treatment
INFLAMMATORY DISEASES (SIALADENITIS)
Bacterial Infections
Acute Bacterial Sialadenitis
Clinical Features
Treatment
Chronic Bacterial Sialadenitis
Clinical Features
Treatment
VIRAL INFECTIONS
Mumps (Epidemic Parotitis)
Clinical Features
Vaccination
Treatment
Cytomegalovirus (CMV) Infection
HIV Infection
Hepatitis C Virus (HCV) Infection
INFLAMMATORY AND REACTIVE LESION
Necrotizing Sialometaplasia
Clinical Features
Treatment
ALLERGIC REACTION OR DISEASE
Allergic Sialadenitis
GRANULOMATOUS CONDITIONS
Sarcoid Sialadenitis
Tuberculosis (TB)
Treatment
IMMUNOLOGICAL DISORDERS
Sjogren's Syndrome (SS) (Primary and Secondary)
Clinical Features
Treatment
Sialadenosis
Clinical Features
Etiological Factors
SALIVARY GLAND TUMORS
Benign Tumors
Pleomorphic Adenoma
Oncocytoma (Acidophilic Adenoma, Oxyphilic Adenoma)
Basal Cell Adenoma
Ductal Papilloma
Myoepithelioma
Malignant Tumors
Adenoid Cystic Carcinoma
Mucoepidermoid Carcinoma
Acinic Cell Carcinoma
Carcinoma Expleomorphic Adenoma
17:
Temporomandibular Joint Disorders
INTRODUCTION
FUNCTIONAL ANATOMY OF TMJ
PATIENT HISTORY
EXAMINATION OF ARTICULATORY SYSTEM
1. Visual Examination
2. Range of Movement
3. Palpation of Joint
4. Palpation of Muscles
5. Palpation of Lymph Nodes Pain Provocation Tests
6. Intraoral Examination
Jaw Jerk Reflex
Jaw Opening Reflex
Etiology of TM Disorders (TMD)
DIFFERENTIAL DIAGNOSIS
DIAGNOSTIC AIDS FOR TMJ DISORDERS
MYOFACIAL PAIN DYSFUNCTION SYNDROME (MPDS)
HISTORY TAKING FOR EVALUATING A PATIENT FOR TEMPOROMANDIBULAR DISCOMFORT
Home Care Instructions to Patient of TMD
Treatment
INTRACAPSULAR DISORDERS OF TEMPOROMANDIBULAR JOINT
Inflammatory Disorders
Rheumatoid Arthritis
Psoriatic Arthritis
Degenerative Joint Disease
Traumatic Disorders
Fractures
Ankylosis
Dislocation
INFECTIONS
Septic Arthritis
Synovial Chondromatosis
Clinical Features
Treatment
Developmental Disorders
Condylar Hyperplasia
Condylar Hypoplasia
Disc Displacement
18:
Orofacial Pain and Abnormalities of Taste
INTRODUCTION
PAIN-RELATED TERMINOLOGY
CLASSIFICATION OF OROFACIAL PAIN
1. Pain due to Diseases of Oral Cavity
2. Pain of Musculoskeletal Origin
3. Neuralgia
4. Vascular Pain
5. Generalized Pain Conditions
6. Psychogenic Pain
7. Orofacial Pains (OFP) or Pathologies which Resemble the Toothache
EVALUATION OF PAIN
ASSESSMENT OF PATIENT WITH OROFACIAL PAIN
History
Physical Examination
Intraoral Examination (IOE)
Range of Motion
Tests of Sensory Discrimination
Diagnostic Studies
SPECIFIC OROFACIAL PAIN CONDITIONS
Neuralgia
Trigeminal Neuralgia (TN)
Geniculate Neuralgia
Glossopharyngeal Neuralgia (GPN)
Occipital Neuralgia
Pain Due to Diseases of Oral Cavity
Pain of Musculoskeletal Origin
Vascular Pain
Migraine
Cluster Headache (CH)
Tension-Type Headache
Mixed Headache
Traction Headache
Cranial Arteritis
Carotodynia
Prevention of Migraine
Generalized Pain Conditions
Central Pain
Post-Traumatic Neuropathic Pain
ATYPICAL OROFACIAL PAIN
ATYPICAL ODONTALGIA (AO)
GLOSSODYNIA
BURNING MOUTH SYNDROME
Treatment of Glossodynia and Burning Mouth Syndrome
ABNORMALITIES OF TASTE
Classification of Taste Disorders
Gustatory-Olfactory Confusion
Secondary Dysgeusias and Parageusias
Transport Disorders
Sensorineural Taste Disorders
Lesions Affecting Central Pathways of Taste
Metabolic Disorders
Pregnancy
Idiopathic Taste Abnormality Age-related Changes of Gustatory Function
Taste Loss in Anosmic Patients (Gustatory-Olfactory Confusions)
Upper Respiratory Tract Infection
Industrial Dusts and Air Pollutants
Secondary Dysgeusias and Parageusias
Transport Disorders
Salivary Hypofunction and Xerostomia
Blocked Taste Bud Pores
Sensorineural Taste Disorders
Inherited Disorders
Damage to Taste Nerves
Lesions Affecting Central Pathways of Taste
Brain Tumor and Cerebrovascular Lesions
Trauma to the Head
Multiple Sclerosis
Metabolic Disorders
Idiopathic Taste Abnormality
19:
Cardiovascular Diseases Related to Oral Medicine
INTRODUCTION
HYPERTENSION
Primary or Essential or Idiopathic Hypertension
Secondary Hypertension
Clinical Features
Management
Oro-dental Considerations
Rapid Control of Hypertension
CORONARY HEART DISEASE (CHD)
Causes of Coronary Heart Diseases are as follows:
Risk Factors For Coronary Heart Disease
Angina Pectoris
Myocardial Infarction
Management of Patient with Coronary Heart Disease in Dental Clinic
VALVULAR HEART DISEASE
Oro-dental Considerations
CONGESTIVE HEART FAILURE
Causes
Clinical Features
Treatment
Dental Considerations
CARDIAC ARRHYTHMIA
Treatment
Dental Considerations
RHEUMATIC FEVER AND RHEUMATIC HEART DISEASE
Clinical Features
Diagnosis
Treatment
Prevention
CONGENITAL HEART DISEASE
Coarctation of Aorta
Oral Manifestations
Tetralogy of Fallot
INFECTIVE ENDOCARDITIS [SUBACUTE BACTERIAL ENDOCARDITIS (SABE)]
Clinical Features
Diagnosis
Treatment
Prevention
Cardiac Conditions in which Endocarditis Prophylaxis is Recommended are as follows:
Dental Procedures in which Endocarditis Prophylaxis is Recommended are as follows:
CAVERNOUS SINUS THROMBOSIS
Clinical Features
Dental Considerations
PERMANENT PACEMAKERS
20:
Diseases of Respiratory System Related to Oral Medicine
INFECTIONS OF UPPER RESPIRATORY TRACT
Acute Rhinitis
Clinical Features
Treatment
Pharyngitis and Tonsillitis
Clinical Features
Treatment
Sinusitis
Clinical Features
Treatment
Dental Considerations
Laryngitis
Acute Laryngitis
Chronic Laryngitis
DISEASES OF LOWER RESPIRATORY TRACT
Chronic Obstructive Pulmonary Diseases
Chronic Bronchitis
Emphysema
Asthma
Etiology
Clinical Features
Treatment
Dental Considerations
Pneumonia
Clinical Features
Treatment
Tuberculosis
Clinical Features
Treatment
Oral Manifestation
Treatment of Oral Lesions
Dental Considerations
OTHER RESPIRATORY DISEASES
Sarcoidosis
Clinical Features
Oral Manifestations
Treatment
Wegener's Granulomatosis
Clinical Features
Oral Manifestations
Treatment
Midline Granuloma
Clinical Features
Oral Manifestations
Treatment
Cystic Fibrosis
Clinical Features
Treatment
Oral Manifestations
Severe Acute Respiratory Syndrome (SARS)
Etiological Agent
Mode of Transmission
Clinical Features
Identifying SARS Patient in Dental Clinic
Preventive Measures
21:
Gastrointestinal Diseases Related to Oral Medicine
ESOPHAGEAL DISEASES
Dysphagia
Esophageal Ulcers
Dental Considerations
PEPTIC ULCERS
Duodenal Ulcers
Clinical Features
Treatment
Dental Considerations
Gastric Ulcers
DISEASES OF LIVER
Jaundice (Icterus)
Hepatitis
Etiology
Clinical Features
Oral Manifestations
Types of Viral Hepatitis
INFLAMMATORY DISEASES OF THE INTESTINE
Ulcerative Colitis
Crohn's Disease
Treatment
Oral Manifestations
Dental Considerations
22:
Renal Diseases and Oral Medicine
CHRONIC RENAL FAILURE
Glomerulonephritis
Pyelonephritis
MANIFESTATIONS OF RENAL DISEASES (UREMIC SYNDROME)
Gastrointestinal
Hematologic
Cardiovascular
Neuromuscular
Metabolic-endocrine
Dermatologic
Immunologic
Oral Manifestations
MANAGEMENT OF CHRONIC RENAL FAILURE (CRF)
Conservative Therapy-Medical Management of Chronic Renal Failure
DIALYSIS
Hemodialysis
Peritoneal Dialysis
Orodental Considerations
KIDNEY TRANSPLANTATION
Clinical Manifestations
Orodental Considerations
ORAL MANIFESTATIONS
23:
Relation of Immunologic Diseases with Oral Medicine
INTRODUCTION
PRIMARY IMMUNODEFICIENCIES
Selective Immunoglobulin Deficiencies
Thymic Hypoplasia
Combined Immunodeficiency
X-linked Agammaglobulinemia
Partial Combined Immunodeficiency with Ataxia Telangiectasia (PCIAT)
Oral Manifestations of Primary Immunodeficiencies
Orodental Management
SECONDARY IMMUNODEFICIENCY
Hodgkin's Disease
Non-Hodgkin's Lymphoma
Leukemia
Multiple Myeloma
Nephrotic Syndrome
ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS)
Immunopathogenesis
Clinical Manifestations
Acute Infections
Asymptomatic Phase
Clinical Signs and Symptoms
Secondary Infections (Opportunistic Infections)
Neoplasms
Oral Lesions Associated with HIV Infection
Viral Infections
Treatment
Fungal Infection-candidiasis
Oral Neoplasms
DISEASES OF THE CONNECTIVE TISSUE
Systemic Lupus Erythematosus (SLE)
Clinical Manifestations
Common Problems
Oral Manifestations
Dental Considerations
Treatment
Dermatomyositis (DM)
Clinical Features
Oral Manifestations
Treatment
Scleroderma (Systemic Sclerosis, Dermatosis, Hidebound Disease)
Oral Manifestations
Treatment
Dental Management
Rheumatoid Arthritis (RA)
Oral Manifestations
Dental Management
Mixed Connective Tissue Disease (MCTD)
ALLERGY
Localized Anaphylactic Reactions
Urticaria
Angioneurotic Edema (Angioedema)
Generalized Anaphylactic Reactions
Treatment
Latex Allergy
24:
Neuromuscular Diseases Affecting the Orofacial Region
MOVEMENT DISORDERS
Cerebral Palsy (CP)
Clinical Features
Treatment
Orodental Considerations
Parkinson's Disease (Parkinsonism, Paralysis Agitans)
Clinical Features
Treatment
Dental Considerations
Bell's Palsy
Clinical Features
Treatment
Guillain-Barrè Syndrome (Acute Idiopathic Polyneuropathy)
Clinical Features
Treatment and Prognosis
Huntington's Chorea [Huntington's Disease (HC)]
Clinical Manifestation
Treatment
Orodental Considerations
MULTIPLE SCLEROSIS (MS)
Clinical Features
Orodental Considerations
Treatment
CEREBRAL ABSCESS
AMYOTROPHIC LATERAL SCLEROSIS (ALS)
Clinical Features
Treatment
Orodental Considerations
MUSCULAR DYSTROPHY (MD)
Clinical Features
Duchenne's Pseudohypertrophic Dystrophy
Facioscapulohumeral Dystrophy
Limb Girdle Dystrophy of ERB (A Type of Paralysis)
Myotonic Dystrophy
Oral Manifestations
Dental Considerations
MYASTHENIA GRAVIS
Clinical Features
Oral Manifestations
Dental Considerations
CEREBROVASCULAR DISEASE
Stroke
Etiology
Clinical Manifestation
Management
Orodental Considerations
EPILEPSY
Clinical Features
Tonic Phase
Clonic Phase
Postictal Phase
Status Epilepticus
Petit Mal Seizure
Treatment
Dental Considerations
Cavernous Sinus Thrombosis (CST)
Clinical Manifestations
Treatment
25:
Diabetes Mellitus and Its Oral Manifestations
INTRODUCTION
ETIOLOGICAL CLASSIFICATION OF DIABETES
Primary Diabetes
Secondary Diabetes or Other Types of Diabetes
A. Pancreatic Disease or Injuries
B. Endocrine Disease
C. Genetic Defects Affecting Beta Cell Function or Insulin Action
D. Drug-induced Diabetes
E. Other Genetic Syndromes (With Associated Diabetes)
F. Infectious (Congenital Rubella, Cytomegalovirus Infection)
Impaired Glucose Tolerance (IGT) and Impaired Fasting Glucose (IFG)
ETIOLOGY OF DIABETES
Type 1 Diabetes (IDDM)
Genetic
Viruses
Stress
Type 2 Diabetes (NIDDM)
Diet
Age
CLINICAL FEATURES
Type 1 Diabetes Mellitus
Type 2 Diabetes Mellitus
COMPLICATIONS OF DIABETES
(A) Diabetic Retinopathy
(B) Diabetic Neuropathy
(C) Macrovascular Disease (Accelerated Atherosclerosis)
(D) Diabetic Coma
(E) Diabetic Nephropathy (Renal Failure)
(F) Alterations in Wound Healing
(G) Cardiovascular (Coronary artery disease)
(H) Cerebrovascular (Stroke)
ORAL MANIFESTATIONS
TREATMENT (MANAGEMENT)
Type 1 Diabetes (IDDM)
Type 2 Diabetes (NIDDM)
ORAL DISEASES IN DIABETES
Periodontal Health and Diabetes
DENTAL MANAGEMENT OF DIABETIC PATIENT
Diabetic Emergencies in the Dental Clinic
Management of Emergency
Hypoglycemia
Treatment
When the Patient is Conscious
When the Patient is Unconscious
Prevention
26:
Hematological Disorders
HEMATOPOIESIS
DISORDERS OF THE WHITE BLOOD CELLS
Qualitative Disorders
Quantitative Disorders
Myeloproliferative Disorders
QUALITATIVE DISORDERS
Chronic Idiopathic Neutropenia
Clinical Features
Treatment
Orodental Considerations
Lazy Leucocyte Syndrome
Clinical Features
Orodental Considerations
Chediak-Higashi Syndrome
Clinical Features
Treatment
Orodental Considerations
QUANTITATIVE DISORDERS
Granulocytosis
Cyclic Neutropenia
Clinical Features
Treatment
Orodental Considerations
Agranulocytosis and Neutropenia
Causes of Neutropenia
Clinical Features
Treatment
Orodental Considerations
MYELOPROLIFERATIVE DISORDERS
Leukemia
Etiology
Acute Leukemia (AL)
Clinical Features
Treatment
Chronic Leukemia
Chronic Granulocytic or Myelocytic Leukemia (CGL or CML)
Clinical Features
Treatment
Chronic Lymphocytic Leukemia (CLL)
Clinical Features
Treatment
Orodental Considerations in Leukemia
ORAL ULCERS
MULTIPLE MYELOMA (MM)
Clinical Features
Oral Manifestations
Treatment
LYMPHOMA
Hodgkin's Disease (HD)
Clinical Features
Treatment
Non-Hodgkin's Lymphoma
Clinical Features
Treatment
Burkitt's Lymphoma (BL)
Clinical Features
Treatment
Orodental Considerations of Lymphoma
DISORDERS OF RED BLOOD CELLS POLYCYTHEMIA
Polycythemia Vera (PV)
Clinical Features
Oral Manifestations
Treatment
Orodental Considerations
Secondary Polycythemia
ANEMIA
Anemia due to Blood Loss
Iron-deficiency Anemia
Clinical Features
Oral Manifestations
Dental Considerations
Treatment
Plummer-Vinson Syndrome
Clinical Features
Anemia due to Decreased Erythrocyte Production
Pernicious Anemia
Clinical Features
Oral Manifestations
Treatment
Folic Acid Deficiency Anemia
Aplastic Anemia
Orodental Considerations
Hemolytic Anemia
Intracorpuscular Defects
Extra Corpuscular Factors
Oral Manifestations
Sickle-Cell Anemia
Clinical Features
Oral Manifestations
Treatment
Orodental Considerations
Thalassemias
α (Alfa)-Thalassemia
β (Beta)-Thalassemia
β (Beta)-Thalassemia Major (Cooley's Anemia)
Treatment
Oral Manifestations
27:
Disorders of Hemostasis and Oral Medicine
NORMAL CLOTTING MECHANISM
Vascular Reaction
Formation of Platelet Plug
Coagulation of Blood
LABORATORY INVESTIGATIONS
Bleeding Time
Clotting Time
Prothrombin Time
Platelet Count
Thrombin Clotting Time
HEMOSTATIC DISORDERS
Coagulation Disorders
Hemophilia A
Hemophilia B
von-Willebrand's Disease (vWD)
Factor V Deficiency
Factor XI Deficiency
Thrombocytopenic Disorders
Classification
Treatment
Congenital Disorders
von-Willebrand's Disease
IDENTIFICATION OF THE PATIENT WITH BLEEDING DISORDERS IN DENTAL CLINIC
ORAL MANIFESTATIONS OF BLEEDING DISORDERS
DENTAL MANAGEMENT OF HEMOPHILIC PATIENTS
Pain Control
Periodontal Treatment
Pedodontic Therapy
Prosthodontic and Restorative Treatment
Endodontic Treatment
Orthodontic Treatment
Oral Surgical Procedures
MANAGEMENT OF PLATELET DISORDERS
Platelet Transfusion
In Emergency (Unplanned) Surgery Controlling the Affect of Aspirin
Controlling the Affect of Chemotherapy
Hemophilias A and B and von-Willebrand's Disease
Local Hemostatic Agents and Techniques
Diet Restriction
MANAGEMENT OF DISSEMINATED INTRAVASCULAR COAGULATION (DIC)
MANAGEMENT OF DRUG-RELATED COAGULATION DISORDERS
MANAGEMENT OF DISEASE-RELATED COAGULATION DISORDERS
Patients on Anticoagulants
28:
Infectious Diseases Related to Oral Medicine
TUBERCULOSIS (TB)
Signs and Symptoms
Predisposing Factors
Oral Manifestations and Considerations
SEXUALLY TRANSMITTED INFECTIONS
BLOOD BORNE INFECTIONS
GONORRHEA
Clinical Features
Treatment
Oropharyngeal Manifestations of Gonorrhea
Pharyngeal Gonorrhea
Gonococcal Stomatitis
CHLAMYDIAL INFECTIONS
Dental Treatment
SYPHILIS
Clinical Features of Acquired Syphilis
Primary Syphilis
Secondary Syphilis
Tertiary Syphilis
Clinical Features of Congenital Syphilis
Treatment
Oral and Facial Manifestations of Syphilis
Primary Syphilis
Secondary Syphilis
Tertiary Syphilis
Congenital Syphilis
GRANULOMA INGUINALE
Clinical Features
Oral Manifestations
LYMPHOGRANULOMA VENEREUM
Clinical Features
Oral Manifestations
HERPES SIMPLEX VIRUS INFECTIONS
Acute Ulcerative Herpetic Gingivostomatitis
Oropharyngeal Herpes Simplex Virus Infection
Clinical Features
Treatment
EPSTEIN-BARR VIRUS INFECTIONS
Infectious Mononucleosis
Clinical Features
Treatment
ORAL CYTOMEGALOVIRUS INFECTION
MOLLUSCUM CONTAGIOSUM (MCV) INFECTION
ORAL CONDYLOMA ACUMINATUM
Viral Infections
Hepatitis C Virus (HCV)
Risk to Dental Health Care Workers (DHCW)
HCV Prevention and Treatment
HIV Infection
Orodental Considerations
Oral Lesions
Drugs Induced Ulceration
Oral Lesions in Children
29:
Endocrine Diseases and Orodental Health
HYPOTHALAMUS AND ANTERIOR PITUITARY
ADRENAL DISEASES AND CONDITIONS
Orodental Considerations
Hemostasis
Prone to Infection
Tolerance to Dental Treatment
THYROID DISEASE
Orodental Considerations
Hemostasis
Prone to Infection
30:
Orodental Medicine in Geriatrics
COMMON SYSTEMIC CONDITIONS IN GERIATRICS AND THEIR ORODENTAL MANAGEMENT
Coagulation Disorders
Immunosuppression
Radiation Hazard
Steroid Treatment
Cardiac Problems
Joint Replacement
AGE-RELATED CHANGES IN ORAL HEALTH IN GERIATRICS
In Oral Mucosa
In Dentition
In Periodontium
Salivary Glands
Mastication and Swallowing
ORAL AND DENTAL DISORDERS IN ELDERLY PEOPLE
Oral Mucosal Diseases
Infectious Diseases
Dental Disorders
Periodontal Diseases
Salivary Gland Dysfunction
Smell and Taste Dysfunction
Swallowing Disorders
Edentulousness
PREVENTION AND TREATMENT OF ORAL CONDITIONS IN AGED INDIVIDUALS
Oral Mucosal Diseases
Infectious Diseases
Dental Disorders
Salivary Gland Disorders
Periodontal Disease
Chemosensory (Smell and Taste) Dysfunction
Masticatory and Swallowing Disorders
Edentulousness
Pain Sensation
31:
Orodental Considerations in Organ Transplantation
ORAL LESIONS
Viral Infections
Fungal Infections
Bacterial Infections
Non-Infectious Oral Lesions
Graft-Versus-Host-Disease (GVHD)
Oral Mucositis
Salivary Gland Dysfunction
Gingival Enlargement
ORODENTAL MANAGEMENT
Pre-transplantation Considerations
Pretransplantation Dental Management
Post-transplantation Considerations
Immediate Post-transplantation Period
Stable Post-transplantation Period
Chronic Rejection Period
32:
MCQs in Oral Medicine
ORODENTAL CONSIDERATIONS IN ORGAN TRANSPLANTATION
ULCERATIVE AND VESICULOBULLOUS LESIONS
RED AND WHITE LESIONS OF THE ORAL MUCOSA
PIGMENTED LESIONS OF THE ORAL TISSUES
BENIGN ORAL TUMORS
MALIGNANT ORAL TUMORS
DISEASES OF THE TONGUE
SALIVARY GLAND DISEASES
TEMPOROMANDIBULAR JOINT DISORDERS
OROFACIAL PAIN AND ABNORMALITIES OF TASTE
CARDIOVASCULAR DISEASES RELATED TO ORAL MEDICINE
DISEASES OF THE RESPIRATORY SYSTEM RELATED TO ORAL MEDICINE
DISEASES OF GASTROINTESTINAL TRACT RELATED TO ORAL MEDICINE
RENAL DISEASES AND ORAL MEDICINE
RELATION OF IMMUNOLOGIC DISEASES WITH ORAL MEDICINE
NEUROMUSCULAR DISEASES AFFECTING THE ORO-FACIAL REGION
DIABETES AND ITS ORAL MANIFESTATIONS
HEMATOLOGICAL DISORDERS
DISORDERS OF HEMOSTASIS AND ORAL MEDICINE
INFECTIOUS DISEASES RELATED TO ORAL MEDICINE
ORODENTAL MEDICINE IN GERIATRICS
33:
Appendices
INDEX
TOC
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