Third Edition
Editor Soumitra Kumar MBBS MD DM
Professor, Division of Cardiology Department of Medicine Vivekananda Institute of Medical Sciences
Kolkata, West Bengal, India
Foreword S Padmavati
Jitendar P Vij
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The Protocol Book
© 2009, Jaypee Brothers Medical Publishers
All rights reserved. No part of this publication should be reproduced, stored in a retrieval system, or transmitted in any form or by any means: electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the editor and the publisher.
First Edition: 2003 (by Editor)
Second Edition: 2008
Third Edition: 2009
9788184485615
Typeset at JPBMP typesetting unit
Printed at Replica Press
To
My family
Friends
and
Well wishers
The secret of religion lies not in theories but in practice.
To be good and to do good — that is the whole of religion.
6Contributors
- Abhijit Bhattacharya
- Consultant Physician
- Sri Aurobindo Seva Kendra and AMRI Hospitals, Kolkata
- Achyut Sarkar
- Assistant Professor
- Department of Cardiology (Paediatric Division)
- Institute of Postgraduate Medical Education and Research, Kolkata
- Amitava Majumder
- Deputy Visiting Physician
- Department of Medicine
- Ramakrishna Mission Seva Pratishthan, Kolkata
- Ananya Biswas
- Registrar, Department of Medicine
- Ramakrishna Mission Seva Pratishthan, Kolkata
- Arnab Dutta
- RMO cum Clinical Tutor
- Department of Cardiology
- Medical College and Hospital
- Kolkata
- Arup Ratan Dutta
- Consultant Nephrologist
- Wockhardt Hospital and Kidney Institute, Kolkata
- Debashis Sarkar
- Consultant Physician
- Sri Aurobindo Seva Kendra, Kolkata
- Jayanta Chakraborty
- Professor
- Department of Medicine
- Vivekananda Institute of Medical Sciences, Kolkata
- Jayanta Roy
- Consultant Neurologist
- AMRI Hospital, Kolkata
- Kaushik Nandy
- Postgraduate Trainee (DNB-Medicine)
- Department of Medicine
- Ramakrishna Mission Seva Pratishthan, Kolkata
- Kinsuk Das
- Consultant Gastro-Enterologist
- Sri Aurobindo Seva Kendra, Kolkata
- Naseem Akhtar
- Deputy Visiting Physician
- Department of Medicine
- Ramakrishna Mission Seva Pratishthan, Kolkata
- Niranjan Banerjee
- Associate Professor (Retired)
- Department of Medicine
- Vivekananda Institute of Medical Sciences, Kolkata
- Paramita Banerjee
- ICCU Medical Officer
- Ramakrishna Mission Seva Pratishthan, Kolkata
- Pinaki Dutta
- Medical Officer
- Department of Medicine
- AMRI Hospital, Kolkata
- Pranita Nandy
- Medical Officer
- Division of Non-Invasive Cardiology
- Ramakrishna Mission Seva Pratishthan, Kolkata
- SR Pal
- Assistant Professor
- Division of Rheumatology
- Department of Medicine
- Vivekananda Institute of Medical Sciences, Kolkata
- Shuvanan Ray
- Head of Cardiology
- Department Cath Lab
- AMRI Hospital (Salt Lake), Kolkata
- Soumitra Kumar
- Professor
- Division of Cardiology
- Department of Medicine
- Vivekananda Institute of Medical Sciences, Kolkata
- Subrata Bhowmick
- Professor
- Division of Nephrology
- Department of Medicine
- Vivekananda Institute of Medical Sciences, Kolkata
- Sudeshna Majumder
- Professor (Retired)
- Department of Medicine
- Vivekananda Institute of Medical Sciences
- Kolkata
- Sujata Majumder
- Resident Physician
- Department of Medicine
- Ramakrishna Mission Seva Pratishthan
- Kolkata
- Sulagna Banerjee
- Medical Officer
- Division of Non-Invasive Cardiology
- Ramakrishna Mission Seva Pratishthan
- Kolkata
- Sumit Sen Gupta
- Consultant Pulmonologist
- Sri Aurobindo Seva Kendra and AMRI Hospital
- Salt Lake
- Kolkata
- Vidya Verma
- Registrar
- Department of Medicine
- Ramakrishna Mission Seva Pratishthan
- Kolkata
The Protocol Book represents guidelines for the diagnosis and management of common medical emergencies seen in hospitals. It covers mostly cardiac problems but also includes respiratory, gastrointestinal and renal diseases and diabetes. It has the same objectives as the American Heart Association/American College of Cardiology's Pocket Guidelines Updates compiled by the special Task Forces of these organisations, which are proving extremely useful for practising physicians.
This book has been compiled by the postgraduate students of the Vivekananda Institute of Medical Sciences, Ramakrishna Mission Seva Pratishthan, Kolkata under the guidance of senior consultants in these departments at the hospital and under the able Editorship of Dr Soumitra Kumar. The text is written in a typical ‘Senior Resident’ language that can be easily understood by their colleagues. The latest ‘state-of-the-art’ information and knowledge has been used in preparing the various sections. It is a very laudable effort on the part of the postgraduate staff.
I am sure The Protocol Book will prove very useful for all categories of physicians dealing with acute emergencies in hospitals.
S Padmavati
frcp (London) frcpe, facc, fams
PRESIDENT—All India Heart Foundation
DIRECTOR—National Heart Institute
9Preface to the Third Edition
The third edition of The Protocol Book in 2009 has come closer to the heels of the second edition in 2008. Significant changes in management guidelines of some leading acute problems (Acute coronary syndrome and pulmonary embolism in particular) have necessitated the publication of the new edition. The previous two editions (2003 and 2008) have been appreciated. The encouragement has continued to stimulate me and the contributors ever since and subsequent editions bear testimony to that.
To make things as lucid and conceivable as possible, data and guidelines have been presented in the form of simple algorithms, tables, etc. as it was done in the previous two editions and the facts and the figures are absolutely updated and evidence-based. Data presented at the important conferences held in 2008 (namely ACC 2008 and ESC 2008) have been incorporated in the new edition. The emphasis remains on successful “total management” of the patient, i.e. addressing all the major problems in a given patient.
I, on behalf of the team of contributors, would like to reiterate that ‘protocol’ for management of any particular medical problem should suffice for majority of the patients with that problem; but, at times, a special approach depending on the circumstances (patient's condition, skill and facilities available, financial situation, etc.) would still be necessary.
As editor, I am personally grateful to all the contributors of this edition for their sincere cooperation and hard work.
I am also thankful to the publishing team of M/s Jaypee Brothers Medical Publishers (P) Ltd., New Delhi for their sincere cooperation and support for the second and the current editions.
Last but not the least, I am grateful to my family members (my parents, wife and son) for their constant inspiration and for bearing with my academic endeavour often at the cost of my family commitments.
Soumitra Kumar
10Preface to the Previous Edition
The first edition of The Protocol Book in 2003 was a sincere and honest attempt to induce a scientifically rational approach in our day-to-day practice. The effort was appreciated and lauded widely and a senior cardiologist had commented as following: “I wonder why nobody has done this before”. Such encouraging words paved the way for the second edition. Thanks once again to M/s Zydus who have continued to extend their support and sponsorship and our endeavour has been significantly bolstered by the involvement of M/s Jaypee Brothers Medical Publishers (P) Ltd, New Delhi, for the second edition.
These days, the practice of medicine is changing at such a pace that many of us find too fast and mind-blowing at times. To make things as lucid and conceivable as possible, data and guidelines have been presented in the forms of simple algorithms, tables, etc. as it was done in the first edition and the facts and figures are absolutely updated and evidence-based. However, as I had emphasized in the first edition, practice of medicine is as much an art as it is a science. Hence, ‘protocol’ for management of any particular medical problem should suffice for majority of the patients with that problem; but, at times, a special approach depending on the circumstances (patient's condition, skill and facilities available, financial situation, etc.) would still be necessary.
All the chapters of the first edition have been retained and four new chapters on “PCI in AMI”, “Rheumatological Emergencies”, “Vascular Emergencies” and “Acute Cardiac Care in Paediatric Practice” have been added along with sections on emergency cardiovascular drugs, antibiotics, etc. Apart from new additions, majority of the old chapters have been virtually rewritten and rest have been thoroughly revised. The focus has been on emergency cardiovascular medicine with near-equal emphasis on common medical emergencies that one comes across in high-dependency units. The emphasis needless to say is on successful “total management” of the patient because a patient undergoing primary PCI will return home only if his hyperglycaemia, azotaemia and dyselectrolytaemia have been addressed as successfully as his PCI has been.11
As editor, I am personally grateful to all the contributors of this edition for their sincere cooperation and hard work. I am thankful to the team of M/s Phildon for their unstinting help in the composition of the manuscript. I am grateful to my family members (my parents, wife and son) for their constant inspiration and for bearing with my academic endeavours often at the cost of my family commitments.
Soumitra Kumar