Recent Advances in Pediatrics (Volume 18): Hot Topics Suraj Gupte, Praveen C Sobti
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1Recent Advances in PEDIATRICS
Volume 18: Hot Topics
Spotlight Hematology and Oncology
Edited by Suraj Gupte Guest Editor Praveen C Sobti
2Jaypee's Other Titles by Prof (Dr) Suraj Gupte
3Recent Advances in PEDIATRICS
Volume 18: Hot Topics
Spotlight Hematology and Oncology
Edited by Suraj Gupte MD, FIAP Professor and Head Postgraduate Department of Pediatrics Narayana Medical College/Narayana General and Superspeciality Hospitals Nellore 524 002, Andra Pradesh, India E-mail: surajgupte@rediffmail.com recentadvances@yahoo.co.uk Honorary Director: Pediatric Education Network Editor: The Short Textbook of Pediatrics, Textbooks of Pediatric Emergencies, Neonatal Emergencies, Pediatric Nutrition, Pediatric Gastroenterology, Hepatology and Nutrition, Towards MRCPCH Part II (Theory Examination, Pediatric Yearbook (Series), Newer Horizons in Tropical Pediatrics, etc. Author: Differential Diagnosis in Pediatrics, Instructive Case Studies in Pediatrics, Pediatric Drug Directory, Infant Feeding, Speaking of Child Care, The Baby Book: The Parents' Guide from Birth to Infancy Co-editor: Asian Journal of Maternity and Child Health (Manila, Philippines) Section and Guest Editor: Pediatrics Today (New Delhi) Editorial Advisor: Asian Journal of Pediatrics Practice (New Delhi) Editorial Advisory Board Member/Reviewer: Indian Journal of Pediatrics (New Delhi), Indian Pediatrics (New Delhi), Synopsis (Detroit, USA), Indian Journal of Pediatric Gastroenterology, Hepatology and Nutrition (Jaipur), Journal of Clinical Pediatrics, Maternal and Child Nutrition (Preston, UK), Journal of Pediatric Infectious Diseases (Turkey) Examiner: National Board of Examinations (NBE) for DNB, New Delhi, All India Institute of Medical Sciences (AIIMS), New Delhi, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Sher-i-Kashmir Institute of Medical Sciences (SKIMS), Srinagar, Indira Gandhi National Open University (IGNOU), New Delhi and several universities Pediatric Faculty Selection Expert: All India Institute of Medical Sciences (AIIMS), Punjab Public Service Commission, Jammu and Kashmir Public Service Commission, Union Public Service Commission
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Recent Advances in Pediatrics
(Volume 18: Hot Topics)
© 2009, Shamma-Bakshi Gupte, Executive Editor
All rights reserved. No part of this publication should be reproduced, stored in a retrieval system, or transmitted in any form or by any means: electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the editor and the publisher.
This book has been published in good faith that the material provided by contributors is original. Every effort is made to ensure accuracy of material, but the publisher, printer and editor will not be held responsible for any inadvertent error (s). In case of any dispute, all legal matters are to be settled under Delhi jurisdiction only.
First Edition: 2009
9788184486612
Typeset at JPBMP typesetting unit
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5To Our dear parents whose inspiration, motivation, blessings and moral support continue to contributea great deal to our academic endeavors and Everybody striving to contribute to child health and welfare for a brighter future globally
6Contributors 10Preface
The 18th volume of the noted international series, Recent Advances in Pediatrics, first launched in 1991 and now concurrently in the 20th special volume (RAP Special Vol 20: Nutrition, Growth and Development), aims at covering topical hot topics. Over and above the general/miscellaneous topics, it incorporates a Spotlight on Pediatric Hematology and Oncology. The 28 state-of-the-art chapters covered by as many as 41 experts drawn from all over the world, attempt to review the depth and breadth of knowledge in the field of contemporary pediatrics with special reference to its applicability in day-to-day life.
Each and every chapter is remarkable by its excellence, providing a stimulating and, not infrequently, even provocative, matured and informed update. Understandably, such an approach is befitting when the goal is not only to inform but also to motivate discussion, interaction, research and innovation.
In keeping with the professed policy of the series, multidisciplinary approach with an eye on future continues to occupy pride of place in this volume too.
We wish to record our indebtedness to our distinguished contributors for providing excellent state-of-the-art chapters in various aspects of adolescence. They were also gracious enough to have confidence in our editorship. Without their understanding and cooperation, this volume wouldn't have seen the light of the day.
Thanks are also due to the Advisory Editorial Board for providing inputs and advice in various editorial matters and peer reviewers for not only providing us the benefit of their critical expertise but also for the promptness in responding to our requests for speedy action.
Dr Praveen C Sobti, Professor of Pediatrics, Dayanand Medical College, Ludhiana, India, deserves our special gratitude for being the Guest Editor to this volume, particularly for the Spotlight on Pediatric Hematology and Oncology.
The moral support and motivation provided by the management and administration of the Narayana Medical College and Hospitals, especially Dr P Narayana, Chairman, Dr CL Venkata Rao, Adviser, Dr S Vijay Kumar, Coordinator, Dr BA Ramakrishna, Principal, and Dr P Narsimha Reddy, Medical Superintendent, for successful completion of this project, is gratefully acknowledged.11
Our daughter, Dr Novy and son, Dr Manu, voluntarily provided all sorts of assistance in taking the project to its logical conclusion.
Our gratitudes are due to M/s Jaypee Brothers Medical Publishers (P) Ltd, New Delhi and their dedicated staff for the skillful production of the book.
Suraj Gupte
Academic Editor
Shamma-Bakshi Gupte
Executive Editor