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Fundamentals of Physiology: A Textbook for Students of Nursing, Medicine, Dentistry and Allied Courses
RL Bijlani
CHAPTER 1:
Getting Introduced to Physiology
THE UNICELLULAR ORGANISM
MULTICELLULAR ORGANISMS
What About the Other Systems?
PRINCIPLES OF REGULATION: CONTROL SYSTEMS
Response Characteristics of a Control System
Additional Complexities in Control Systems
Variable Set Point
Anticipatory Control
PHYSIOLOGY AS THE BASIS OF MEDICINE
QUESTIONS
ANSWERS
CHAPTER 2:
Fundamentals of Cell Biology
THE CELL MEMBRANE
Cell Junctions
Tight Junctions
Gap Junctions
Desmosomes
THE ORGANELLES
Rough Endoplasmic Reticulum
Polyribosomes
Smooth Endoplasmic Reticulum
Microsomes
The Golgi Complex
Lysosomes
Peroxisomes
Recycling of the Membrane
Mitochondria
Cytoskeletal Elements
Microfilaments
Microtubules
Cilia
Flagellum
Centriole
Functions of Cytoskeletal Elements
INCLUSIONS
NUCLEUS
COMMUNICATION BETWEEN CELLS
CELL DIVISION
Mitosis
Prophase
Metaphase
Anaphase
Telophase
Meiosis
GENETICS
Molecular Basis of Genes
The Basis of Similarity and Variety
From DNA to Characters
From DNA to Proteins
From Proteins to Characters
Regulatory Genes
Inheritance of Characteristics
Modes of Inheritance
Appearance of New Characters
Homozygosity
Mutations
Environment
The Human Genome Project
CONCLUSION
QUESTIONS
ANSWERS
CHAPTER 3:
Physicochemical Principles of Biological Transport
PASSIVE TRANSPORT
Simple Diffusion
Facilitated Diffusion
Osmosis
Ultrafiltration
Dialysis
ACTIVE TRANSPORT
Secondary Active Transport
Coupled Transport
Co-transport
Counter-transport
Solute-solvent Interaction
Osmosis
Solvent Drag
QUESTIONS
ANSWERS
CHAPTER 4:
Blood
PLASMA
Plasma Proteins
Origin
Functions
RED BLOOD CELLS
ANEMIA
Causes of Anemia
Anemia due to Decreased Production of RBC
Anemia due to Increased Destruction of RBC
Anemia due to Abnormal Loss of Blood
Iron Deficiency Anemia
Folic Acid and Vitamin B12 Deficiency Anemias
Folic Acid Deficiency Anemia
Vitamin B12 Deficiency Anemia
JAUNDICE
Physiological Jaundice
WHITE BLOOD CELLS
Types of WBC
Neutrophils
Eosinophils
Basophils
Monocytes
Lymphocytes
IMMUNE MECHANISMS
Innate Immunity
Phagocytosis
Acquired Immunity
T and B Lymphocytes
Humoral Immunity
Cell Mediated Immunity
Vaccines
PLATELETS
COAGULATION
Dissolution of the Clot
Vitamin K and Coagulation
Anticoagulants
Hemophilia
HEMOPOIESIS
Regulation of Erythropoiesis
BLOOD GROUPS
ABO System
Inheritance of ABO Blood Groups
Rh System
Rh incompatibility
Special Risk in Rh Negative Girls
Blood Transfusion
Grouping
Cross Matching
Universal Donor and Recipient
Reactions to a Mismatched Transfusion
Risks of Blood Transfusion
QUESTIONS
ANSWERS
CHAPTER 5:
Cardiovascular System
THE ROUTE OF CIRCULATION
CARDIAC MUSCLE
Pacemaker and Conduction Tissue
RESTING MEMBRANE POTENTIAL
Potassium
Chloride
Sodium
Proteins
ACTION POTENTIAL
Pacemaker Potential
Ionic Basis of Action Potential
THE CARDIAC IMPULSE
PROPERTIES OF CARDIAC MUSCLE
Automaticity
Rhythmicity
Long Refractory Period
All or None Law
Length-tension Relationship
ELECTROCARDIOGRAPHY
Configuration of the ECG
The ECG Leads
Bipolar Limb Leads
Augmented Limb Leads
Unipolar Chest Leads
Electrodes
Configuration of the Electrocardiogram
Electrical Axis of the Heart
CARDIAC CYCLE
CARDIAC OUTPUT
Determination of Cardiac Output
Factors Affecting Cardiac Output
Factors Affecting Stroke Volume
Factors Affecting Heart Rate
ARTERIES
CAPILLARIES
Fluid Exchange across Capillaries: Starling's Hypothesis
LYMPHATICS
Functions of Lymphatics
EDEMA
VEINS
What Kejpg Blood Flowing in the Veins
REGULATION OF CARDIOVASCULAR FUNCTION
Neural Center for Cardiovascular Regulation
Mediation of Effects of Cardiovascular Centers
Baroreceptor Reflex
Chemoreceptor Reflex
CNS Ischemic Response
Local Regulation
Axon Reflex
Changes in Gas Tension
Metabolites
Mediators of Inflammatory Response
Factors Affecting Blood Pressure
Regulation of Blood Pressure
Short-term Regulation
Long-term Regulation
Hypertension
Classification of Hypertension
CORONARY CIRCULATION
Regulation of Coronary Blood Flow
Neural Regulation
Chemical Regulation
CORONARY ARTERY DISEASE
SHOCK
Hypovolemic Shock
Cardiogenic Shock
Neurogenic Shock
Anaphylactic Shock
Septic Shock
QUESTIONS
ANSWERS
CHAPTER 6:
Respiratory System
FUNCTIONAL ANATOMY
Volumes and Capacities
Tidal Volume
Inspiratory Reserve Volume
Expiratory Reserve Volume
Residual Volume
Total Lung Capacity
Inspiratory Capacity
Functional Residual Capacity
Vital Capacity
Some More Volumes Relevant to Pulmonary Physiology
Minute Volume
Maximum Voluntary Ventilation
Dead Space
Pulmonary Ventilation and Alveolar Ventilation
MECHANICS OF BREATHING
Inspiration
Expiration
Thoracic, Abdominal and Clavicular Breathing
Respiratory Pressures
Intrapulmonary or Alveolar Pressure
Interpleural Pressure or Pleural Pressure
Compliance
Surfactant
Airway Resistance
OXYGEN TRANSPORT
Diffusion
Dalton's Law of Partial Pressures
Oxygen Transfer in the Lungs
Oxygen Transport in Blood
Oxygen Transfer in the Tissues
CARBON DIOXIDE TRANSPORT
Carbon Dioxide Transfer in the Tissues
Carbon Dioxide Transport in Blood
Dissolved Carbon Dioxide
Bicarbonate
Carbamino Compounds
Carbon Dioxide Transfer in the Lungs
Haldane Effect
Relationship between Haldane Effect and Bohr Effect
REGULATION OF RESPIRATION
Neural Regulation of Respiration
Medullary Respiratory Centers
Pontine Respiratory Centers
Higher Neural Influences
Respiratory Reflexes
Chemical Regulation of Respiration
Central Chemoreceptors
Peripheral Chemoreceptors
PULMONARY FUNCTION TESTS
Tests of Ventilation
Tests of Diffusion
Tests of the End-result of Respiration
Test of Response to Respiratory Stimulants
Tests during Exercise
Conclusion
APPLIED RESPIRATORY PHYSIOLOGY
Hypoxia
Hypoxic Hypoxia
Anemic Hypoxia
Stagnant Hypoxia
Histotoxic Hypoxia
Cyanosis
Central Cyanosis
Peripheral Cyanosis
Dyspnea
Breathing Reserve
Increased Work of Breathing
Orthopnea
Breath Holding
Cheyne-Stokes Breathing
Respiratory Failure
Oxygen Toxicity
Artificial Respiration
Manual Methods
Mechanical Methods
QUESTIONS
ANSWERS
CHAPTER 7:
Adaptation to Environment
REGULATION OF BODY TEMPERATURE
What is Normal Temperature
Heat Balance
Factors Promoting Heat Gain
Factors Promoting Heat Loss
Temperature Regulatory Mechanisms
The Classical Model of Thermoregulation
Fever
ACCLIMATIZATION TO HOT ENVIRONMENT
HEAT SYNDROMES
Heat Cramps
Heat Exhaustion
Heat Stroke
ACCLIMATIZATION TO COLD ENVIRONMENT
Hypothermia
LIFE AT HIGH ALTITUDE
Effects of Acute Exposure to High Altitude
Hyperventilation
Work Capacity
2,3-diphosphoglycerate Concentration
Central Nervous System Effects
Acclimatization to High Altitude
Hyperventilation
Large Chest
Polycythemia
Increased Vascularity of Tissues
Improved Ability of Tissues to Use Oxygen
Exercise at High Altitude
Maladaptation to High Altitude
High Altitude Pulmonary Edema
Acute Mountain Sickness
Chronic Mountain Sickness
CONCLUSION
QUESTION
ANSWER
CHAPTER 8:
Gastrointestinal System
FUNCTIONAL ANATOMY
Blood Supply
Nerve Supply
Enteric Nervous System
Afferent Nerves
Efferent Nerves
Interaction between Enteric Nervous System and Autonomic Nervous System
Higher Neural Influences
FOOD IN THE MOUTH
Salivary Secretion
Functions of Saliva
Regulation of Salivary Secretion
Swallowing
The Swallowing Reflex
FOOD IN THE STOMACH
Regulation of Gastric Secretion
Agents that Stimulate Parietal Cells
Agents that Inhibit Parietal Cells
Meal-related Gastric Secretion
Cephalic Phase
Gastric Phase
Intestinal Phase
Digestive Function of Gastric Secretion
Regulation of Gastric Emptying
Functions of the Stomach
PEPTIC ULCER
Factors which Increase Secretion
Genetic Factors
Food
Psychosomatic Factors
Factors which Decrease Mucosal Defence
Defective Mucus
Drugs
Alcohol
Smoking
Helicobacter Pylori
PANCREATIC SECRETION
Regulation of Pancreatic Secretion
Hormonal Mechanisms
Neural Mechanisms
BILE
Regulation of Biliary Secretion
THE SMALL INTESTINE
Carbohydrate Digestion and Absorption
Absorption of Glucose
Absorption of Fructose and Galactose
Protein Digestion and Absorption
Absorption of Amino Acids
Fat Digestion and Absorption
Water and Electrolyte Absorption
Absorption of Cyanocobalamin (Vitamin B12)
Absorption of Iron
Absorption of Heme Iron
Absorption of Nonheme Iron
Regulation of Iron Absorption
THE LARGE INTESTINE
Absorption
Fermentation
Carbohydrate Fermentation
Protein Fermentation
Fermentation of Fats and Related Compounds
Beneficial Effects of Intestinal Microflora
Storage
MOTILITY OF THE GUT
Stomach
Small Intestine
Large Intestine
Defecation Reflex
GASTROINTESTINAL FUNCTION TESTS
D-xylose Absorption Test
Fecal Fat
Schilling's Test
FUNCTIONS OF THE LIVER
Secretion of Bile
Bile Salt Synthesis
Bile Salt Secretion
Bacterial Metabolism
Intestinal Absorption
Hepatic Uptake and Secretion
Metabolic Functions
Carbohydrate Metabolism
Lipid Metabolism
Protein Metabolism
Immunological Functions
Other Functions
LIVER FUNCTION TESTS
Tests of Detoxification and Excretory Function
Serum Bilirubin
Urinary Bilirubin
Urinary Urobilinogen
Bromsulphalein Excretion
Rose Bengal Excretion
Tests of Protein Metabolism
Serum Proteins
Flocculation Tests
Coagulation Tests
Tests of Bile Acid Metabolism
Serum Bile Acids
Serum Cholesterol
Tests of Bile Duct Patency
Alkaline Phosphatase
Other Enzymes
Bile Pigments
Tests of Hepatocellular Damage
Transaminases
Lactic Dehydrogenase
Conclusion
QUESTIONS
ANSWERS
CHAPTER 9:
Nutrition and Metabolism
ENERGY METABOLISM
Energy Intake
Energy Expenditure
Basal Metabolism
Thermic Effect of Feeding
Thermic Effect of Activity
CARBOHYDRATES
Chemistry
Monosaccharides
Disaccharides
Polysaccharides
Complex Carbohydrates
Sources
Physiological Role
Digestible Carbohydrates
Indigestible Carbohydrates: Dietary Fiber
Carbohydrate Requirements
FATS
Chemistry
Triglycerides
Other Lipids
Sources
Essential Fatty Acids
Functions of EFA
Deficiency
Requirements
The Lipid-coronary Connection
Biochemistry of Atherosclerosis
Dietary Recommendations for Coronary Heart Disease
PROTEINS
Chemistry
Essential Amino Acids
Protein Quality
Sources
Protein Requirements
VITAMINS
Vitamin A
Sources
Functions
Requirements
Deficiency
Vitamin D
Sources
Functions
Requirements
Deficiency
Vitamin E
Sources
Functions
Requirement
Deficiency
Vitamin K
Sources
Functions
Requirements
Deficiency
Thiamine
Sources
Functions
Requirements
Deficiency
Riboflavin
Sources
Functions
Requirements
Deficiency
Niacin
Sources
Functions
Requirements
Deficiency
Pantothenic Acid
Sources
Functions
Requirements
Deficiency
Biotin
Sources
Functions
Requirements
Deficiency
Pyridoxine
Sources
Functions
Requirements
Deficiency
Folic Acid
Sources
Functions
Requirements
Deficiency
Cobalamin
Sources
Functions
Requirements
Deficiency
Folate-B12 interaction
Ascorbic Acid
Sources
Functions
Requirements
Deficiency
Vitamin Pills: Yes or No
MINERALS
Calcium
Sources
Functions
Requirements
Deficiency
Phosphorus
Sources
Functions
Requirements
Deficiency
Iron
Sources
Functions
Requirements
Deficiency
Iodine
Sources
Functions
Requirements
Deficiency
Zinc
Sources
Functions
Requirements
Deficiency
Selenium
Source
Functions
Requirements
Deficiency and Toxicity
Sodium
Sources
Functions
Requirements
Deficiency and Excess
Potassium
Sources
Functions
Requirements
Deficiency
Fluorine
Sources
Functions
Requirements
Deficiency and Excess
Mineral Supplements
RECOMMENDED DIETARY ALLOWANCES
BALANCED DIET
Framing a Balanced Diet
Scientific Specifications
Translating the Specifications into a Diet
NUTRITION DURING PREGNANCY AND LACTATION
Nutritional Requirements during Pregnancy
Energy
Nutrients
Other Considerations
Nutritional Requirements during Lactation
Energy
Nutrients
Other Considerations
NUTRITION DURING INFANCY AND CHILDHOOD
Nutrition from Birth Onwards
Advantages of Breastfeeding
Anti-infective Properties
Digestive Properties
Growth Factors
Supplements
The Protein Myth
Tips for Feeding Children
QUESTIONS
ANSWERS
CHAPTER 10:
Excretory System
FUNCTIONAL ANATOMY
MECHANISM OF URINE FORMATION
Glomerular Filtration
Proximal Tubule
Loop of Henle
The Distal Tubule and Collecting Duct
Functional Segments of the Nephron
ROLE OF KIDNEYS IN ACID BASE BALANCE
Mechanism of Reabsorption of Bicarbonate
Generation of Fresh Bicarbonate
Buffers in Tubular Fluid
Ammonia Buffer
Phosphate Buffer
Regulation of Acid-base Balance
PHYSIOLOGY OF MICTURITION
Functional Anatomy
Innervation
Mechanics of Micturition
Filling of the Bladder
Emptying of the Bladder
Neural Mechanism of Micturition
QUESTIONS
ANSWERS
CHAPTER 11:
Endocrine System
CLASSIFICATION OF HORMONES
MECHANISM OF ACTION OF HORMONES WITH INTRACELLULAR RECEPTORS
MECHANISM OF ACTION OF HORMONES WITH CELL MEMBRANE RECEPTORS
Hormone-induced Activation of Adenylyl Cyclase
Other Second Messengers
HYPOTHALAMIC AND PITUITARY HORMONES
Hypothalamic Control of Anterior Pituitary
Transport of Releasing Hormones to the Anterior Pituitary
Action of Releasing Hormones
Regulatory Role of Hypothalamic and Anterior Pituitary Hormones
Anterior Pituitary Hormones
Growth Hormone
Prolactin
Follicle Stimulating Hormone
Luteinizing Hormone
Thyroid Stimulating Hormone
Adrenocorticotropic Hormone
Melanocyte Stimulating Hormone
Posterior Pituitary Hormones
Antidiuretic Hormone
Oxytocin
THYROID GLAND
Hormones of the Thyroid Gland
Synthesis of Thyroid Hormones
Transport of Thyroid Hormones
Functions of Thyroid Hormones
Calorigenic Effect
Growth and Development
Effects on Substrate Metabolism
Systemic Effects
Mechanism of Action of Thyroid Hormones
Regulation of Thyroid Secretion
Disorders of the Thyroid Gland
Hypothyroidism
Hyperthyroidism
Goiter
PARATHYROID GLANDS
Regulation of Parathyroid Hormone Secretion
OTHER HORMONES AFFECTING CALCIUM METABOLISM
Calcitriol
Calcitonin
ADRENAL CORTEX
Mechanism of Action
Glucocorticoids
Actions of Cortisol
Regulation of Glucocorticoid Secretion
Excess Glucocorticoid Secretion: Cushing's Syndrome
Deficient Glucocorticoid Secretion: Addison's Disease
Mineralocorticoids
Actions of Aldosterone
Regulation of Aldosterone Secretion
Excess Aldosterone Secretion: Conn's Syndrome
Deficient Aldosterone Secretion
Androgens
Abnormal Secretion: Adrenogenital Syndrome
ADRENAL MEDULLA
Actions of Catecholamines
Regulation of Catecholamine Secretion
Excess Catecholamine Secretion
PANCREAS
Insulin
Actions of Insulin
Mechanism of Action
Regulation of Insulin Secretion
Regulation of Plasma Glucose
Pathophysiology of Diabetes Mellitus
Glucagon
Actions
Regulation of Glucagon Secretion
Glucagon Excess
GASTROINTESTINAL HORMONES
QUESTIONS
ANSWERS
CHAPTER 12:
Reproductive System
SEX DETERMINATION
Sex Chromatin
GENERAL SCHEME OF REPRODUCTIVE FUNCTION
PUBERTY
Why is Hormonal Secretion Low in Childhood?
What Increases the Hormonal Secretion at Puberty
MALE REPRODUCTIVE SYSTEM
Functional Anatomy
Spermatogenesis
Sertoli Cells
Hormonal Regulation of Spermatogenesis
Semen
Functions of Seminal Vesicles
Functions of the Prostate Gland
Characteristics of Semen
Deposition of Semen in the Female Genital Tract
Fate of Semen in the Female Genital Tract
Functions of Testosterone
Role before Birth
Secondary Sex Characteristics
Role in Spermatogenesis
Anabolic Effect
Mechanism of Action of Testosterone
FEMALE REPRODUCTIVE SYSTEM
Functional Anatomy
The Menstrual Cycle
Ovarian Cycle
Uterine Cycle
Hormonal Regulation of the Menstrual Cycle
Ovarian Hormones
Estrogen
Progesterone
Relaxin
Menopause
Mechanism
Treatment
PREGNANCY
Fertilization
Implantation
The Pregnant vs Non-pregnant Uterus
The Placenta
Functions of the Placenta
Fetoplacental Unit
Parturition
LACTATION
Secretion and Ejection of Milk
Milk Ejection Reflex
Lactational Amenorrhea
CONTRACEPTION
Contraceptives for Men
Inhibiting Spermatogenesis
Vasectomy
Condom
Contraceptives for Women
Inhibiting Ovulation
Preventing Ovum Transport: Tubectomy
Diaphragm and Cervical Cap
Intrauterine Contraceptive Devices
Preventing Growth and Development of the Zygote
QUESTIONS
ANSWERS
CHAPTER 13:
Physiology of Locomotion
FUNCTIONAL ANATOMY OF SKELETAL MUSCLE
Muscle Fiber
Organization of Contractile Elements
Sarcoplasmic Reticulum
RESTING MEMBRANE POTENTIAL
TWO STEPS TO ACTIVATION
ACTION POTENTIAL
Ionic Basis of Action Potential
NEUROMUSCULAR TRANSMISSION
Functional Anatomy of the Neuromuscular Junction
Physiology of Neuromuscular Transmission
Release of Acetylcholine
Effect of Acetylcholine on the Postsynaptic Membrane
End Plate Potential
Fate of Acetylcholine
Pharmacology of Neuromuscular Transmission
Depolarizing Type Blockers
Nondepolarizing Type Blockers
Reversible AChE Inhibitors
Irreversible AChE Inhibitors
CONTRACTION OF SKELETAL MUSCLE
Stimulus–response Relationship in Skeletal Muscle
Effect of Frequency of Stimulation on Contraction
Regulation of Force of Contraction in the Body
Isometric and Isotonic Contraction
Length–tension Relationship in Isometric Contraction
ELECTROMYOGRAPHY
SMOOTH MUSCLE
Structure of Smooth Muscle
Classification
Electrophysiology
Resting Membrane Potential
Action Potential
Modes of Stimulation of Smooth Muscle
Excitation–Contraction Coupling
Contractile Process
PHYSIOLOGY OF NERVE FIBERS
Conduction of the Nerve Impulse
Compound Action Potential
Classification of Nerve Fibers
A Alpha
A Beta
A Gamma
A Delta
Group B
Group C
Response of Nerve Fibers to Injury
QUESTIONS
ANSWERS
CHAPTER 14:
Nervous System: General Concepts
COORDINATION NEEDS COMMUNICATION
REFLEX ARC AND REFLEXES
CEREBROSPINAL FLUID
Functional Anatomy
Formation of CSF
Circulation of CSF
Absorption of CSF
Functions of CSF
Providing Optimum Environment to Neurons
Homeostatic Role
Removal of Proteins
Protection
Clinical Physiology of CSF
Examination of CSF
Raised CSF Pressure
Blood Brain Barrier
SYNAPTIC TRANSMISSION
Structure of a Synapse
The Process of Synaptic Transmission
Arrival of the Message
Release of Neurotransmitter
Development of Postsynaptic Potentials
Summation of Postsynaptic Potentials
Generation and Conduction of Action Potential
Fate of the Neurotransmitter
Central Neurotransmitters
QUESTIONS
ANSWERS
CHAPTER 15:
Nervous System: Sensory Functions
SKIN
TRANSDUCTION
Receptor Potential
ACTION POTENTIAL
ADAPTATION
FROM PERIPHERY TO CENTER
Dorsal Column System
Anterolateral System
Thalamus
The Cerebral Cortex
Cognition, Conation and Affect
Labeled Line Code
Weber–Fechner Law
DESCENDING FIBERS OF THE SENSORY SYSTEM
PAIN
Pain Pathways
Modulation of Pain
Gate Control Theory
Endogenous Pain Relief System
Revaluation of the Gate Control Theory
Referred Pain
Life Without Pain
VISION
Functional Anatomy
Aqueous Humor
Optics of Vision
Refraction in the Eye
Reduced Eye
Errors of Refraction
Retinal Function
Structure of the Retina
Excitation of Retina
Visual Pathways
Visual Reflexes
Light Reflex
Accommodation Reflex
Argyll Robertson Pupil
Eye Movements
Visual Perception
Color Vision
Color Blindness
HEARING
The External Ear
The Middle Ear
The Inner Ear
Ultrastructure of Hair Cells
Innervation of the Cochlea
Function of the Inner Ear
Auditory Pathways
Ascending Auditory Pathway
Descending Auditory Pathways
Perception of Different Characteristics of Sound
Frequency
Intensity
Direction
Pattern
Interpretation of Speech
Hearing Defects
Conduction Deafness
Sensorineural Deafness or Nerve Deafness
Evaluation of Auditory Function
Tuning Fork Tests
Audiometry
TASTE
Taste Receptors
Taste Pathways
The Four Basic Tastes
Transduction, Coding and Perception of Gustatory Stimuli
SMELL
Olfactory Receptors
Olfactory Pathways
The Primary Odors
Transduction, Coding and Perception of Olfactory Stimuli
CONCLUSION
QUESTIONS
ANSWERS
CHAPTER 16:
Nervous System: Motor Functions
SPINAL MOTOR MECHANISMS
Stretch Reflex
Reflex Arc for the Stretch Reflex
Role of Gamma Motor Neurons
Stretch Reflex as a Control System
Functional Role of the Stretch Reflex
Inhibitory Interneurons
Golgi Tendon Organs
Renshaw Cells
Flexion Reflex
Crossed Extension Reflex
BRAIN STEM MOTOR MECHANISMS
Vestibular and Neck Reflexes
Vestibular Apparatus
Vestibular Reflexes
Neck Reflexes
Pathways for Vestibular and Neck Reflexes
Reticular Formation
Decerebrate Rigidity
Mechanism of Decerebrate Rigidity
CORTICAL MOTOR MECHANISMS
Posterior Parietal Cortex
Premotor Cortical Areas
Primary Motor Cortex
Overview of Cortical Motor Mechanisms
THE CEREBELLUM
Functional Anatomy of the Cerebellum
Functions of the Cerebellum
Vestibulocerebellum
Spinocerebellum
Cerebrocerebellum
Role of Cerebellum in Motor Learning
Overview
Effects of Cerebellar Lesions
BASAL GANGLIA
Structure
Afferent Connections
Internuclear Connections
Efferent Connections
Functions
Motor Functions
Other Functions
Parkinson's Disease
CONCLUSION
QUESTION
ANSWER
CHAPTER 17:
Nervous System: Visceral Functions and Motivation
AUTONOMIC FUNCTIONS
Functional Anatomy
Neurotransmitters in ANS
Physiological Role of ANS
Higher Neural Regulation of ANS
LIMBIC SYSTEM
Functional Anatomy
Neocortical Structures
Archicortical Structures
Subcortical Structures
Connections
Functions
Emotions: Experience and Expression
Memory
Learning
Preservation of Self
Preservation of Species
Kluver-Bucy Syndrome
HYPOTHALAMUS
Functional Anatomy
Connections
Hypothalamo-hypophysial Relationships
Blood-brain Barrier in the Hypothalamus
Functions of Hypothalamus
Temperature Regulation
Regulation of Food Intake
Regulation of Water Balance
Reproduction
Emotions
Autonomic Control
Endocrine Functions
Sleep
Circadian Rhythms
CONCLUSION
QUESTIONS
ANSWERS
CHAPTER 18:
Nervous System: Sleep-wakefulness and Higher Functions
RETICULAR FORMATION
Anatomy
Efferent Connections
Afferent Connections
Functions
Modulation of Pain
Regulation of Tone and Posture
Autonomic Control
Sleep-wakefulness
ELECTROENCEPHALOGRAPHY
Physiological Basis of EEG
EEG Waveforms
Alpha Waves
Beta Waves
Theta Waves
Delta Waves
SLEEP-WAKEFULNESS
Architecture of Sleep
Physiological Variation with Age
Slow Wave Sleep
REM Sleep
Neural Structures Involved in Sleep-wakefulness
Circadian Nature of the Sleep-wakefulness Cycle
Neurotransmitters Involved in Sleep-wakefulness
Sleep Producing Substances
SPEECH
Broca's Area
Wernicke's Area
Mechanism of Speech
Aphasias
Motor Aphasia
Sensory Aphasia
Conduction Aphasia
LEARNING
Classical Conditioning
Operant Conditioning
Biological Basis of Learning
MEMORY
Neural Substrate of Memory
Cellular and Molecular Basis of Memory
Long-term Potentiation
CONCLUSION
QUESTION
ANSWER
CHAPTER 19:
Vital Regulations
PHYSIOLOGY OF EXERCISE
Cardiovascular Responses to Exercise
Increase in Skeletal Muscle Blood Flow
Redistribution of Blood Flow
Cardiac Output
Blood Pressure
Effect of Training on Cardiovascular Function
Respiratory Responses to Exercise
Mechanism of Respiratory Responses to Exercise
Effect of Training
Response of Muscles to Exercise
Endurance Training
Strength Training
Endocrine Responses to Exercise
Metabolic Adjustments in Exercise
Effect of Training
Fatigue
Site of Fatigue
Other Factors Associated with Fatigue
Conclusion
PHYSIOLOGY OF FLUID BALANCE
Fluid Compartments of the Body
Blood Volume
Regulation of Blood Volume and the Volume of Other Body Fluids
Short-term Regulation
Long-term Regulation
REGULATION OF ACID-BASE BALANCE
Physiological Buffers
Bicarbonate Buffer
Protein Buffer
Phosphate Buffer
Limitations of Buffers
Respiration and Acid-base Balance
Kidneys and Acid-base Balance
Fate of Secreted Hydrogen Ions
Relative Importance of Different Mechanisms
Disturbances of Acid-base Balance
CONCLUSION
QUESTION
ANSWER
CHAPTER 20:
Yoga
WHAT IS YOGA
SCHOOLS OF YOGA
Hatha Yoga
Raja Yoga
Yama
Niyama
Asana
Pranayama
Pratyahara
Dharana
Dhyana
Samadhi
The Triple Path: The Yoga of the Gita
Integral Yoga
THE YOGIC ATTITUDE
Dealing with the Ego
Dealing with Desires
Surrender
Universal Love
Sincerity
THE YOGIC PRACTICES
Asanas
Asanas for Relaxation
Asanas for Physical Exercise
Asanas for Meditation
Pranayama
Meditation
Ignore
Reject
Record
PHYSIOLOGICAL EFFECTS OF YOGA
Physical Endurance
Cardiovascular Effects
Respiratory Effects
Metabolic Rate
Effects on the Nervous System
Endocrine Changes
Other Biochemical Changes
YOGA IN HEALTH AND DISEASE
Orthopedic Problems
Hypertension
Coronary Heart Disease
Diabetes
Bronchial Asthma
Psychological Problems
MECHANISMS UNDERLYING EFFECTS OF YOGA
CONCLUSION
QUESTIONS
ANSWERS
INDEX
TOC
Index
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