Index

Liver Transplantation Dilip Chakravarty K, WC Lee, YY Jan, YC Chain, Po-Huang Lee

CHAPTER 1:History of Liver Transplantation
- INTRODUCTION
- HISTORY OF LIVER TRANSPLANTATION
- CONCEPT OF LIVING DONOR LIVER TRANSPLANTATION (LDLT)
- HISTORICAL REVIEW OF IMMUNOSUPPRESSION
CHAPTER 2:Anatomy of Liver
- INTRODUCTION
- EMBRYOLOGY
- LIGAMENTS OF LIVER (FIGURE 2.1)
- LOBAR AND SEGMENTAL ANATOMY OF LIVER
- ANATOMICAL RELATIONS AROUND THE HILUM
- INTRAHEPATIC BILIARY ANATOMY (FIGURE 2.7)
- ANATOMICAL VARIATIONS IN THE PORTAL VEIN
  - PORTAL VEIN IN A LIVE DONOR
- ANATOMY OF HEPATIC VEINS
CHAPTER 3:UNOS, Organ, Allocation Policy and MELD Score
- INTRODUCTION
- PROPOSED PROGNOSTIC MODELS FOR ESTIMATING PROGNOSIS IN LIVER DISEASE
  - NON-DISEASE-SPECIFIC CRITERIA
  - DISEASE-SPECIFIC CRITERIA
- ORGAN ALLOCATION SYSTEM IN USA AND LIVER TRANSPLANTATION
- FUTURE TRENDS IN ORGAN ALLOCATION
  - MELD SCORE AND LDLT
CHAPTER 4:Indications and Contraindications of Liver Transplantation
- INTRODUCTION
- EVALUATION OF THE RECIPIENT AT THE TRANSPLANTATION CENTER (TABLE 4.1)
- INDICATIONS FOR LIVER TRANSPLANTATION (TABLE 4.2)
  - TRAUMA AS AN INDICATION FOR LIVER TRANSPLANTATION
- CONTRAINDICATIONS TO LIVER TRANSPLANTATION (TABLE 4.3)
CHAPTER 5:Liver Transplantation Team
- INTRODUCTION
- THE TEAM
CHAPTER 6:Evaluation of Live Donor
- INTRODUCTION
  - CORE ANTIBODY (HBcAb) POSITIVE DONORS
- DONOR EVALUATION
- MR CHOLANGIOGRAPHY FOR BILIARY TREE EVALUATION (FIGURES 6.10 AND 6.11)
  - INFORMED CONSENT BEFORE TRANSPLANT
- DONOR COMPLICATIONS
  - FOLLOW-UP OF DONOR (FIGURES 6.12 AND 6.13)
- RADIOLOGICAL EVALUATION OF POTENTIAL TRANSPLANT RECIPIENT
CHAPTER 7:Graft Volume Estimation and Donor with Fatty Liver
- INTRODUCTION
  - 3-D CT IMAGING AND VOLUMETRY8,20
- GRAFT VOLUME ESTIMATION
  - SPLIT LIVER
- FATTY CHANGE—DONOR SELECTION
  - PREVALENCE OF HEPATIC STEATOSIS
  - PREDICTION OF EARLY GRAFT FUNCTION IN LDLT44
CHAPTER 8:Liver Donation after Brain Death and Cardiac Death
- INTRODUCTION
- SOURCES OF DONOR ORGAN
- PATHOPHYSIOLOGICAL CHANGES AFTER BRAINSTEM DEATH
  - HEMODYNAMIC CHANGES
  - CARDIOVASCULAR CHANGES
    - Hyperdynamic Phase
    - Cardiovascular Collapse Phase
- MONITORING OF BRAIN DEAD DONOR
- COMMON PROBLEMS IN ORGAN DONORS
- CARE OF THE DONOR
- SYNONYMS
- ETHICAL ISSUES
- PROCEDURE FOR HARVESTING DCD DONORS
CHAPTER 9:Marginal Donor and Donor Risk Index
- MARGINAL DONORS
  - DONORS > 80 YEARS
- DONOR RISK INDEX
  - CALCULATION OF DONOR RISK INDEX (DRI)12
  - SURVIVAL RATES ACCORDING TO DONOR RISK INDEX4
- ORGAN PATIENT INDEX (OPI)23
CHAPTER 10:Donor Surgery
- DECEASED DONOR HEPATECTOMY
CHAPTER 11:Graft Preservation and Bench Procedure
- INTRODUCTION
- CRYOPRESERVATION OF VASCULAR GRAFTS
- BACK TABLE PROCEDURE/BENCH PROCEDURE
  - LIVE DONOR
  - DECEASED DONOR
CHAPTER 12:Recipient Surgery
CHAPTER 13:Reperfusion Syndrome and Preservation Injury
- INTRODUCTION
- ETIOLOGY OF PRS
- PREVENTION AND TREATMENT OF REPERFUSION SYNDROME
- PRESERVATION INJURY
CHAPTER 14:Technical Modifications in Recipient Surgery
- PRE-TRANSPLANT PV THROMBOSIS IN RECIPIENT
- CAVOPORTAL HEMITRANSPOSITION (CPHT)
  - COMPLICATIONS OF CPHT34–37
- PORTAL VEIN ARTERIALIZATION (PVA)
- PREVIOUS SHUNT PROCEDURES
CHAPTER 15:Small for Size Syndrome
- INTRODUCTION
- PROPOSED DEFINITION OF SMALL FOR SIZE SYNDROME (SFSS)
  - SMALL FOR SIZE DYSFUNCTION (SFSD)
  - SMALL FOR SIZE NON-FUNCTION (SFSNF)
- MEDICAL MANAGEMENT OF SFSS
CHAPTER 16:Split Liver Transplantation
- INTRODUCTION
- PROCEDURES
- TYPES OF SPLITTING THE DONOR LIVER
  - DIFFERENCE IN IN-SITU AND EX-SITU SPLIT
- SURGICAL TECHNIQUES: SPLIT LIVER FOR ADULT AND CHILD (EXTENDED RIGHT LOBE AND LATERAL SEGMENT)
  - SURGICAL TECHNIQUE (IN-SITU TECHNIQUE) (FIGURE 16.1)
  - OUR CENTER TECHNIQUES IN SPLIT LIVER FOR 2 ADULTS
CHAPTER 17:Dual Grafts
- INTRODUCTION
- DIFFERENT DUAL GRAFTS THAT CAN BE USED IN LDLT
- RECIPIENT OPERATION
  - TWO LEFT LOBE GRAFTS (FIGURE 17.1)
    - Technical Difficulties
  - TECHNICAL MODIFICATION5,22,29
- USE OF RIGHT LOBE AND LEFT LATERAL SEGMENT/LEFT LOBE GRAFT (FIGURE 17.2)5,21,30
  - RECIPIENT OPERATION
  - VANISHING GRAFT SYNDROME (VGS) IN DUAL GRAFTS
CHAPTER 18:Auxiliary Partial Orthotopic Liver Transplantation (APOLT)
- INTRODUCTION
- INDICATIONS OF APOLT17
  - CITRULLINEMIA
- SURGICAL TECHNIQUE22–25
- DIFFERENT GRAFT TYPES THAT CAN BE USED FOR APOLT
  - LEFT APOLT IN THE RECIPIENT
- TECHNICAL DIFFICULTIES
  - PORTAL INFLOW MODULATION IN APOLT
  - ADVANTAGES OF APOLT
- ISSUES RELATED TO DETRANSPLANTATION
- SURVIVAL RATES AFTER APOLT
- ROLE OF APOLT IN PRESENT TRANSPLANTATION SCENARIO
CHAPTER 19:Domino Liver Transplantation
- INTRODUCTION
- FAMILIAL AMYLOID POLYNEUROPATHY (FAP)
- MSUD17
- DOMINO DDLT
- DOMINO LDLT
- SURGICAL TECHNIQUES FOR USING THE WHOLE LIVER IN DOMINO RECIPIENT27
- DONOR OPERATION IN THE FAP PATIENT (RECOVERY OF THE LIVER IN THE FAP PATIENT)
- DOMINO TRANSPLANTATION PROCEDURE IN THE SECOND RECIPIENT
CHAPTER 20:Postoperative Care and Immunosuppression
- INTRODUCTION
  - GENERAL CARE DURING POST-TRANSPLANTATION PERIOD
- ANTIFUNGAL TREATMENT
  - PROPHYLAXIS
  - CYTOMEGALOVIRUS PROPHYLAXIS
- ANTIVIRAL TREATMENT
- COMMON IMMUNOSUPPRESSIVE DRUGS USED IN LTX
- TOLERANCE
  - TOLERANCE AND THE LIVER IN THE CLINIC
- GRAFT FUNCTION AND GRAFT REGENERATION IN RECIPIENT
  - POSTOPERATIVE EVALUATION OF GRAFT FUNCTION15
  - EVALUATION OF GRAFT REGENERATION15
CHAPTER 21:Immunosuppression Drugs
- INTRODUCTION
- IMMUNOSUPPRESSION IN LIVER TRANSPLANTATION
- EARLY CELL CYCLE INHIBITORS
  - CALCINEURIN INHIBITORS (CINS)
- LATE CELL CYCLE INHIBITORS
  - SIROLIMUS (SRL)
    - Side Effects
- ANTIMETABOLITES
  - MYCOPHENOLATE MOFETIL (MMF)
  - AZATHIOPRINE (AZA)
- ANTIBODY THERAPY
  - MUROMONAB-CD3
    - Side Effects
  - ANTI-INTERLEUKIN-2 RECEPTOR ANTIBODIES (BASILIXIMAB, DACLIZUMAB)
    - Pharmacokinetics
    - Side Effects107
- PEDIATRIC IMMUNOSUPPRESSION
  - INITIAL IMMUNOSUPPRESSION
- NEWER IMMUNOSUPPRESSION DRUGS
CHAPTER 22:Hepatic Hemodynamics and Role of Doppler Ultrasonography
- PORTAL FLOW AND PORTAL VENOUS PRESSURE (PVP) MEASUREMENT
  - GRAFT PORTAL FLOW ESTIMATION
- MEASUREMENT OF PORTAL FLOW
  - DIFFERENT METHODS OF FLOW MEASUREMENT
- POSTOPERATIVE DUS PROTOCOLS
CHAPTER 23:ABO-Incompatible Liver Transplantation
- INTRODUCTION
- DIFFERENT TREATMENT MODALITIES USED FOR IN ABO-INCOMPATIBLE TRANSPLANTATION8–10
CHAPTER 24:Electrolyte Abnormalities in ESLD
- INTRODUCTION
- ELECTROLYTE DISTURBANCE
  - SODIUM
    - Hyponatremia
- MAINTENANCE OF SODIUM LEVEL
  - HYPONATREMIA
    - Central Pontine Myelinosis (CPM)
    - Hypernatremia
  - POTASSIUM
    - Hypokalemia
- MAINTENANCE OF POTASSIUM LEVELS
- ACID-BASE DISTURBANCES
CHAPTER 25:Immunology of Transplantation
- CELLULAR BASIS OF REJECTION
- HUMAN LEUCOCYTE ANTIGEN (HLA) AND REJECTION
- CHIMERISM
- PSYCHOLOGICAL FACTORS IN REJECTION
- ANTIBODY MEDIATED/HYPERACUTE REJECTION
  - ABO-INCOMPATIBLE LTX
CHAPTER 26:Early Complications of Liver Transplantation
- INTRODUCTION
- INITIAL POOR FUNCTION
  - ASSESSMENT OF GRAFT FUNCTION
- ACUTE CELLULAR REJECTION
  - PATHOGENESIS OF ACR
  - ROLE OF C4d IN ACUTE REJECTION
  - SYMPTOMS AND SIGNS OF ACUTE CELLULAR REJECTION
  - DIAGNOSIS
    - Doppler Ultrasonography (DUS)
    - Liver Biopsy
  - REACTIVATION OF HCV AND REJECTION
  - LATE ONSET OF ACUTE REJECTION (LAR)
  - TREATMENT
    - Steroid Resistant Rejection
  - RESPONSE TO TREATMENT OF ACR
- CHRONIC REJECTION
  - PATHOPHYSIOLOGY
  - DIAGNOSIS
  - HISTOLOGIC FEATURES
  - TREATMENT
- HYPERACUTE REJECTION
  - MECHANISM OF INJURY
  - PRE-TRANSPLANT CONDITIONING
  - ROLE OF C4d IN THE HUMORAL REJECTION
  - CLINICAL PRESENTATION
  - DIAGNOSIS
  - DIFFERENTIAL DIAGNOSIS
  - TREATMENT
  - SURVIVAL RESULTS
- LYMPHOCYTE CROSS MATCH TEST
  - PROCEDURE
- INCIDENCE
- TECHNICAL ISSUES RELATED TO BILIARY COMPLICATIONS IN DDLT
- TECHNICAL ISSUES RELATED TO BILIARY COMPLICATIONS IN LDLT
  - SUTURES AND TECHNIQUES OF ANASTOMOSIS
- COMPLICATIONS IN THE RECIPIENT
  - PRESENTATION OF BILIARY COMPLICATIONS
  - BILE LEAK
  - BILIARY STRICTURES
    - Types of Biliary Strictures59,60
  - CLASSIFICATION OF BILIARY STRICTURE
  - CAUSES OF MICROANGIOPATHY AND IMMUNOGENICITY
  - DIAGNOSIS OF BILIARY COMPLICATIONS
- BILE LEAK
- BILIARY STRICTURE
  - ANASTOMOTIC BILIARY STRICTURE IN DDLT
  - NON-ANASTOMOTIC STRICTURES IN DDLT115
  - ANASTOMOTIC BILIARY STRICTURES IN LDLT (FIGURES 26.12 TO 26.33)
  - NON-ANASTOMOTIC BILIARY STRICTURES IN LDLT
- OTHER BILIARY COMPLICATIONS IN THE RECIPIENT
  - SLUDGE AND STONE FORMATION
  - SPHINCTER OF ODDI DYSFUNCTION
  - REDUNDANT BILE DUCT AFTER LTX
  - EXTRAHEPATIC BILE DUCT NECROSIS
- BILIARY COMPLICATIONS IN DONORS
  - BILE LEAK AND INJURY
    - Bile Leak
    - Treatment
- INJURY TO THE CONFLUENCE OF THE HEPATIC DUCTS
- PORTAL VEIN COMPLICATIONS
  - PV STENOSIS
  - PV THROMBOSIS
  - LATE PV ANEURYSM AFTER TRANSPLANTATION
  - HEPATIC VEIN COMPLICATIONS
    - Diagnosis48
    - Treatment
  - OCCLUSION / STENOSIS OF MHV GRAFT IN RIGHT LOBE LDLT (FIGURES 26.34 AND 26.35)
    - Diagnosis
    - Treatment
  - INFERIOR VENA CAVA THROMBOSIS
    - Presentation of IVC Thrombosis
    - Treatment Options
- ARTERIAL COMPLICATIONS
  - HEPATIC ARTERY STENOSIS
  - HEPATIC ARTERY THROMBOSIS
- ARTERIAL STEAL SYNDROME
  - DIFFERENT MECHANISMS OF SASS
  - DIAGNOSIS
    - Angiography
    - 3-D CT Scan
  - DIFFERENTIAL DIAGNOSIS
  - TREATMENT3,8,11–14
  - FOLLOW-UP
- INTRODUCTION
- CLASSIFICATION
  - EARLY INFECTIONS
  - LATE INFECTIOUS
- ABDOMINAL INFECTIONS
  - WOUND RELATED INFECTIONS
  - BILOMAS
    - Treatment
  - PERITONITIS
- PULMONARY INFECTIONS
- CNS INFECTIONS
- BACTERIAL INFECTIONS
  - MYCOBACTERIUM TUBERCULOSIS
  - LEGIONELLA PNEUMOPHILA INFECTION
  - NOCARDIA
  - LISTERIA MONOCYTOGENES
- VIRAL INFECTIONS
  - CYTOMEGALOVIRUS INFECTION (CMV)
  - CLINICAL COURSE OF CMV INFECTION
  - EPSTEIN–BARR VIRUS (EBV)
  - HIV POSITIVE RECIPIENT
  - HERPES SIMPLEX VIRUS
  - VARICELLA ZOSTER VIRUS
  - OTHER VIRUSES
- FUNGAL INFECTIONS
  - CANDIDA INFECTION
  - ASPERGILLUS INFECTION
    - Diagnosis87
    - Treatment
  - CRYPTOCOCCUS
  - PNEUMOCYSTIS CARINII / JIROVECI
- PROTOZOA
  - TOXOPLASMA GONDII
- PARASITES
  - STRONGYLOIDES STERCORALIS
  - VACCINATION
  - HELICOBACTER PYLORI AND LTX
CHAPTER 27:Role of Liver Biopsy in Transplantation
- LIVER BIOPSY
  - DIFFERENT APPROACHES FOR LIVER BIOPSY
- DONOR LIVER BIOPSY
  - BODY MASS INDEX (BMI)
- RECIPIENT LIVER BIOPSY
CHAPTER 28:Renal Dysfunction in Liver Transplantation
- INTRODUCTION
- ACUTE RENAL INJURY AFTER LIVER TRANSPLANTATION
  - TREATMENT
  - DRUG CLEARANCE BY DIALYSIS
- CHRONIC RENAL DISEASE AFTER LIVER TRANSPLANTATION
  - HYPERKALEMIA AND LIVER TRANSPLANTATION
CHAPTER 29:Long-term Care of Recipient
- INTRODUCTION
- OBESITY
  - ETIOLOGY
  - MANAGEMENT
- DIABETES MELLITUS
  - RISK FACTORS FOR PTDM31–41
  - TREATMENT
    - Monitoring of Blood Glucose in Post-transplant Period
    - Treatment Recommendations
- DYSLIPIDEMIA
- METABOLIC SYNDROME
- CARDIAC DISEASE
- HYPERTENSION
  - RISK FACTORS85
  - TREATMENT
- OSTEOPOROSIS
- EFFECT OF CORTICOSTEROIDS ON BONES100–103
  - INVESTIGATIONS
  - TREATMENT
    - Aim of Treatment
- HYPERURICEMIA
- MALIGNANCY
  - RISK FACTORS FOR POST-TRANSPLANT MALIGNANCIES110,114,117–120
  - SURVIVAL
CHAPTER 30:Pregnancy after Liver Transplantation
- INTRODUCTION
- CONTRACEPTION AFTER TRANSPLANTATION
- TIME INTERVAL BETWEEN TRANSPLANTATION AND PREGNANCY
- IMMUNOSUPPRESSIVE DRUGS AND PREGNANCY
- DELIVERY IN LIVER TRANSPLANT RECIPIENT
- BREASTFEEDING
CHAPTER 31:Recurrent Diseases after Liver Transplantation
- INTRODUCTION
- HEPATITIS C VIRUS
- HEPATITIS B VIRUS
  - TREATMENT OF RECIPIENT: HBIG THERAPY
  - TREATMENT OF RECIPIENT: ORAL ANTIVIRAL AGENTS
- AUTOIMMUNE HEPATITIS
- PRIMARY BILIARY CIRRHOSIS
- PRIMARY SCLEROSING CHOLANGITIS
- ALCOHOLIC LIVER DISEASE
- HEREDITARY HEMOCHROMATOSIS
- NONALCOHOLIC STEATOHEPATITIS (NASH)
- RECURRENT BUDD-CHIARI SYNDROME
- HEPATOCELLULAR CARCINOMA
CHAPTER 32:Retransplantation
- INTRODUCTION
- PREDICTIVE FACTORS OF OUTCOME AFTER RE-TX2,5–8,14
- SURVIVAL AFTER RE-TX
CHAPTER 33:Pediatric Liver Transplantation
- INTRODUCTION
- ISSUES RELATED TO PEDIATRIC PRETRANSPLANT CARE
- DONOR POOL FOR PEDIATRIC TRANSPLANTATION
  - ADVANTAGES OF LDLT1
- REDUCED-SIZE LIVER TRANSPLANTATION (RSLT)
- SPLIT LIVER TRANSPLANTATION
  - SMALL FOR SIZE SYNDROME
  - SELECTION OF GRAFT
- INDICATIONS
  - EXTRAHEPATIC BILIARY ATRESIA (EHBA)
  - DRUG TOXICITY
- ACUTE LIVER FAILURE
- ROLE OF MULTI-VISCERAL TRANSPLANTATION IN CHILDREN
- POSTOPERATIVE COMPLICATIONS
- POST-TRANSPLANT LIFE IN CHILDREN
  - COMPLIANCE
    - Major Risk Factors
    - Minor Risk Factors
  - CAUSES OF NONCOMPLIANCE IN CHILDREN17,18
    - Methods to Monitor
CHAPTER 34:Anesthesia in Liver Transplantation
- INTRODUCTION
- PREOPERATIVE ASSESSMENT
- INTRAOPERATIVE MANAGEMENT
- MONITORING OF PATIENT PRIOR TO INDUCTION
- SPECIFIC CONSIDERATIONS
- ROLE OF REGIONAL ANESTHESIA
- POST-TRANSPLANT PERIOD
- LIVER TRANSPLANTATION AND COAGULOPATHY
- ANESTHESIA FOR ACUTE LIVER FAILURE
  - PREOPERATIVE PREPARATION
  - ROLE OF HEPATECTOMY AS A BRIDGE TO TRANSPLANTATION
CHAPTER 35:Extracorporeal Liver Supporting Systems
- INTRODUCTION
- MOLECULAR ADSORBENT RECIRCULATION SYSTEM (MARS)
- PROMETHEUS SYSTEM [FRACTIONATED PLASMA SEPARATION, ADSORPTION, AND DIALYSIS (FPSA)]
- SINGLE PASS ALBUMIN DIALYSIS (SPAD)
- BIOARTIFICIAL LIVER SUPPORT
- CONCLUSIONS
CHAPTER 36:Health-related Quality of Life
- INTRODUCTION
- FATIGUE AFTER LTX10
- EMPLOYMENT AFTER TRANSPLANTATION
- PSYCHOLOGICAL COMPLICATIONS
- HCV AND HRQL
- IMMUNOSUPPRESSION AND HRQL
- MELD SCORE AND HRQL
- REJECTION AND HRQL
- SEXUAL LIFE AFTER LIVER TRANSPLANTATION
- PSYCHOLOGICAL PROBLEMS IN PATIENTS ON WAITING LIST
- HRQL IN PEDIATRIC TRANSPLANTATION
- PSYCHOLOGICAL COMPLAINTS IN DONORS
  - DIFFERENT PSYCHOLOGICAL COMPLAINTS IN THE DONOR
CHAPTER 37:Liver Transplantation in Asia and Western Countries
- INTRODUCTION
- LIVER TRANSPLANTATION IN ASIAN COUNTRIES
- LIVER TRANSPLANTATION IN WESTERN COUNTRIES
- LIVER TRANSPLANTATION IN EUROPE
CHAPTER 38:Hepatocellular Carcinoma and Liver Transplantation
- INTRODUCTION
- STAGING OF HCC
- DIAGNOSIS
- BCLC STAGING CLASSIFICATION AND TREATMENT (BARCELONA CLINIC LIVER CANCER)94
- TREATMENT STRATEGY ACCORDING TO BCLC STAGING (FLOW CHART 38.1)
- BRIDGING THERAPY
- OTHER HEPATIC TUMORS
CHAPTER 39:Hepatitis B Virus and Liver Transplantation
- HEPATITIS B VIRUS
- HBV AND LIVER TRANSPLANTATION
CHAPTER 40:Hepatitis C Virus and LiVer Transplantation
- HEPATITIS C VIRUS
- HCV AND LIVER TRANSPLANTATION
CHAPTER 41:Alcoholism and Liver Transplantation
- INTRODUCTION
- SOCIAL ISSUES RELEVANT TO ALCOHOLISM
- SOCIAL ISSUES AFTER TRANSPLANTATION
  - RECIDIVISM
  - COMPLIANCE
- OTHER ISSUES
  - OSTEOPENIA
  - MALIGNANCIES
CHAPTER 42:Autoimmune Liver Diseases
- INTRODUCTION
- AUTOIMMUNE LIVER DISEASES
- AUTOIMMUNE HEPATITIS (AIH)
- PRIMARY BILIARY CIRRHOSIS (PBC)
  - TREATMENT
    - Medical Management
    - Surgical Management
  - INDICATIONS FOR LIVER TRANSPLANTATION IN PBC
- PRIMARY SCLEROSING CHOLANGITIS (PSC)
- OVERLAP SYNDROME
CHAPTER 43:Acute Liver Failure
- INTRODUCTION
- EPIDEMIOLOGY OF ALF
  - ALF IN ASIAN COUNTRIES
  - ALF IN USA AND UK
- PATHOPHYSIOLOGY
  - APOPTOSIS
  - NECROSIS
    - Other Factors
- LABORATORY INVESTIGATIONS
- PROGNOSTIC CRITERIA IN ALF: CLICHY CRITERIA AND KING'S COLLEGE
  - CLICHY CRITERIA (1986)
    - Limitations31,32
    - The King's College Criteria (1989)
  - CRITERIA IN PEDIATRIC AGE GROUP
- LIVER TRANSPLANTATION IN ALF
  - ROLE OF APOLT (AUXILIARY PARTIAL ORTHOTOPIC LIVER TRANSPLANTATION)
  - ROLE OF LDLT
- MEDICAL MANAGEMENT OF ACUTE LIVER FAILURE
- SURVIVAL
CHAPTER 44:Metabolic Liver Diseases
- INTRODUCTION
- ALPHA 1-ANTITRYPSIN DEFICIENCY
- CYSTIC FIBROSIS
- HEREDITARY HEMOCHROMATOSIS (HHC)
- ALAGILLE SYNDROME
CHAPTER 45:Non-alcoholic Fatty Liver Disease
- INTRODUCTION
- NON-ALCOHOLIC STEATOHEPATITIS (NASH)
- PRETRANSPLANT EVALUATION OF NASH RELATED CIRRHOSIS PATIENT
- CLINICAL OUTCOME IN NAFLD
CHAPTER 46:Wilson's Disease
- INTRODUCTION
- SIGNS AND SYMPTOMS4,5
- DIAGNOSIS8–10
- TREATMENT14,15
- PROGNOSIS17
- FOLLOW-UP
CHAPTER 47:Budd-Chiari Syndrome
- INTRODUCTION
- PRESENTATION
- DIAGNOSTIC WORK UP
- TREATMENT
  - MEDICAL TREATMENT
    - Thrombolytic Therapy
    - Interventional Therapy19–23
- SURGICAL MANAGEMENT
- LIVER TRANSPLANTATION
- RECURRENCE
CHAPTER 48:Recent Advances in Liver Transplantation
- INTRODUCTION
CHAPTER 49:Complications of ESLD

INDEX

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Index

Chapter Notes