Principles and Practice of Burn Care LC Gupta, Sujata Sarabahi, VK Tiwari, Arun Goel
INDEX
A
Abdomen 283
Accelerated acute rejection 76
Accidental burns 520
Acetic acid 301
Acid-base balance 140
metabolic acidosis 140
metabolic alkalosis 141
respiratory acidosis 141
Acidosis 146
Activities of burn unit 543
Acute care area 538
Acute hand burns 362
Acute hospital management 136
Acute radiation syndrome 315
Acute rejection 76
Acute renal failure 142
causes 143
intrinsic renal failure 144
prerenal failure 143
diagnostic approach 144
biomarkers 144
serum creatinine 144
serum cystatin C 144
urinary indices 144
urine volume 144
dialysis modalities 147
types 147
etiological factors 142
management 146
mode of renal replacement therapy 147
anticoagulation 147
vascular access 147
prevention 144
non-pharmacological strategies 144
other therapeutic measures and novel therapies 145
pharmacological strategies 145
prognosis 148
quantifying and classifying 143
supportive treatment 146
acidosis 146
fluid balance 146
hyperkalemia 146
nutritional support 147
pulmonary edema 146
wound evaluation 153
Acute stage 346
Adjuvant therapy to modulate energy requirement and promote wound healing 445
hormonal therapy 446
immunotherapy 446
role of albumin in burns 446
severely burned ICU patients 447
role of early physiotherapy 449
role of environmental and clinical factors 448
role of immunonutrition/immunomodulators in burns and critically ill patients 448
Adjuvant therapy to modulate energy requirement and promote wound healing 445
Admission criteria 104
Aftercare of burned hands 371
Age and sex distribution 10
Aims of local burn wound care 156
Air Zimmer dermatome 184
Airway patency 108
Alcohol burns 307
Alkali (strong) 301
Allograft skin bank program 543
Amniotic membrane 223
Amputations 378, 507
Anabolic phase 435
Anatomical and physiological basis for excision 197
Anatomical considerations 362
Anatomy of dermis 21
Anatomy of epidermal appendages 20
hair follicle 20
sebaceous glands 20
sweat glands 21
Anatomy of epidermis 18
Anemia in burn patient 40
Anesthesia and analgesia for burn dressing 220
Anesthesia during excision 200
Anesthesia for thermally injured 208
anesthetic management 210
hypermetabolic stabilization phase 211
induction of anesthesia 214
maintenance of anesthesia 215
monitoring 216
reconstructive phase 217
resuscitation phase 210
local and regional anesthesia 220
pathophysiology 208
cardiovascular changes 208
immunologic changes 210
metabolic changes 210
respiratory system changes 209
Anesthetic management 210
Angiogenesis 58
Antemortem and postmortem burns 518
Antibacterial therapy 89
Antibiotics for deep infections 91
Anticoagulation 147
Apligraft 227
Application of graft 188
Arterial pressure 115
Assessment of burn injury 393
Assessment of nutritional support 444
Associated local conditions in patients with contractures 474
Assorted acids 301
Autologous keratinocyte culture 236
Automation in culture and sensitivity 88
B
Bacitracin 171
Bacteremia 243
Balancing oxygen supply and demand 426
Baseline body weight 115
Basic principle underlying burn prevention strategies 14
Basics of radiation 313
Basis for topical therapy 167
Behavior of transplanted tissue 74
Biobrane 226
Biological analysis of wounds 83
antibacterial therapy 89
antibiotics for deep infections 91
systemic antibiotic use and its guidelines 90
topical therapy 89
automation in culture and sensitivity 88
gas liquid chromatography 89
polymerase chain reaction 88
culture and sensitivity of wound specimens 85
other microbiological methods 87
processing of wound specimens 84
sample transport 84
wound-sampling methods 83
wound fluid sampling 83
wound tissue sampling methods 83
Biological dosimetry 316
Biological dressings 163
Biomarkers 144
Biopsy 236
Blast injury 27
Blood gases 115
Blood loss during excision 204
Blood loss from donor areas 190
Blood supply of skin 22
Bodenheim knife 184
Body temperature 115
Bone and joint deformities 508
Boutonniere deformity 461
Braithwaite knife 184
Breast 499
Breathing 110
Buprenorphine 123
Burns associated with building fires 8
Burn deaths 8
Burn disaster response team 553
Burn disasters 547
Burn disfigurement and physical impairment calculations 527
impairment and disability 527
Indian legal enforcements 531
legal rights of burn survivors to compensation 531
plight of burn survivor 529
prevention of disability 532
Rehabilitation Council of India Act, 1992 532
Burns of all levels of severity occurring in a community 8
Burn index 518
Burn injuries in married female 526
Burn injury management in disasters 546
burn disasters 547
fire disasters 547
Burn prevention program 543
Burn problem 9
Burn rates 9
Burn registry 8
Burn surface area assessment 104
Burn unit admission criteria 107
Burn unit antibiogram 256
Burn unit referral 106
Burn wound 196
advantages 205
complications 205
problems 205
anatomical and physiological basis for excision 197
criteria for early excision 198
indications 198
blood loss during excision 204
en block excision 205
advantages 205
problems 205
general principles 198
investigations 199
tangential excision 200
anesthesia during excision 200
technique of tangential excision 201
types of burn wound excision 197
primary excision 197
secondary excision 197
types of primary excision 197
escharectomy and delayed skin grafting 197
sequential excision 197
subfascial excision 197
suprafascial full thickness excision 197
tangential excision 197
Burn wound impetigo 258
Burn wound infection 241
burn unit antibiogram 256
surgical treatment 256
clinical features 245
local signs 245
etiopathogenesis 241
fungal infection in burns 248
management 248
primary 250
secondary 251
tertiary 252
microorganisms and their sources in burn wound contamination 242
types of organisms 243
terminology 243
bacteremia 243
colonization 243
non-invasive wound infection 243
septicemia 243
viral infection in burns 248
Burn wound infections 95
Burns disasters in India 548
epidemiology 548
Burns during pregnancy 405
etiology 405
management 406
medical treatment 406
surgical treatment 408
pathophysiology 405
Burns of perineum and external genitalia 383
etiology 383
management 385
pathogenesis 383
prevention of contractures 386
prevention of infection 385
urinary diversion 385
wound management 385
Burns of special sites 283
abdomen 283
scalp 283
management 283
upper extremity and lower extremity 284
Butorphenol 124
C
Calcaneal deformity 465
Calculating nutrient requirement 439
Carbohydrates 438
Carbon monoxide poisoning 132
Cardiac output, mixed venous oxygen tension 115
Cardiovascular and pulmonary complications 281
Cardiovascular changes 208
Cardiovascular system 427
Casualty 537
Causes of death in burns 519
Cellular response and inflammation 55
Cement 301
Central venous pressure 115
Chemical burn 28, 102, 299
Chemical classes 292
Chemical mediators of inflammation 55
Chemotherapeutic agents 52
Chest radiograph 116
Chromic acid 302
Chronic rejection 76
Chronic unhealed areas 508
Cigarette 16
Circumstances of injury 11
Classification according to burn depth estimating burn depth 31
Classification according to severity of burns 35
critical burn 35
grading of burns 35
minor burns 35
moderate burns 35
Classification of burn according to etiology 25
chemical burn 28
electrical burn 28
friction burns 30
laser burns 30
radiation burn 30
thermal burns 25
blast injury 27
flame burns 25
scald burns 26
thermal contact burn 27
Classification of burns 516
Dupuytren's classification 516
Clinical classification 517
Clinical features 128, 245, 336
Coal tar burns 307
Collagen 224
Colonization 243
Common element in successful burn prevention programs 14
Communications 560
Complications of parenteral nutrition 443
Complications of skin grafting 193
Composite epidermal and dermal replacement 229
Conservative management 175
Conservative treatment 173
Consider possible strategies 14
Constructional considerations 540
Continuity of care program 543
Contractures of axilla 489
Control of inflammatory stimuli 426
Control of wound/scar contraction and scar contracture 479
Convalescent care area 539
Corium 21
Corrosive burns 518
Creatinine and blood urea nitrogen 116
Criminal negligence 526
Criteria for a good antimicrobial agent 167
Criteria for early excision 198
Critical burn 35
Crowded places (theater) 16
Cryopreservation 232
Culture and sensitivity of wound specimens 85
Cultured allogenic keratinocytes 229
Cultured keratinocytes 229
Cultured keratinocytes allograft 77
Cutaneous radiation syndrome 318
Cyanide poisoning 133
D
Debridement 156
Deep dermal and full thickness burns 174
Deep fascia 22
Deep freezing or cryopreservation 232
Delayed application of graft 190
Dependency exercise 467
Dermal replacement 227, 228
biological 228
synthetic 227
Dermoepidermal 517
Design of burn unit 538
Design the intervention 15
Development of malignancy 509
Diagnostic approach 144
Dialysis modalities 147
Diclofenac 124
Disaster management in India 550
Disaster plan in action 564
Disasters 546
Distal interphalangeal joint problems 376
District control rooms 560
Document the problem 14
Donor areas 183
Dressing change 190
Dressing room 541
Dressing technique 162
Dupuytren's classification 516
Duration of exposure 517
Duration of use 467
Dysregulated apoptosis 421
E
Ear burn 121, 352
Early management of major burn 108
primary survey 108
airway patency 108
breathing 110
secondary survey 111
Early rehabilitative care 124
Early surgery for burns of hand 364
Early versus late enteral nutrition 440
Ebb or shock phase 435
Eccrine glands 21
Ectropion of eyelids 486
Effect of current supply on human body 265
Effects of burns 517
Electric arc 265
Electric current 264
Electric shock or electrocution 269
Electrical burn 16, 28, 103, 220, 263
complication 281
cardiovascular and pulmonary complications 281
neurological complications 281
effect of current supply on human body 265
epidemiology 263
physics of electricity 264
electric arc 265
electric current 264
resistance 264
type of current 264
unit of current 264
voltage 264
treatment 278
local wound management 278
types of electrical injuries 268
electric shock or electrocution 269
flame injuries 269
flash burns 268
lightning 269
true electrical injury 268
Electrical burns and pregnancy 285
Electrocardiographic monitoring 115
Electrolytes 116
Elemental sodium, potassium and lithium burns 305
Emergency operations center 560
En block excision 205
Endotoxin 70
Energy 438
Enteral nutrition by tube feeding 441
Environment control 540
Enzymatic debridement 176
Epidemiology of burns 7
burn registry 8
sources of burn data 8
burn deaths 8
burns associated with building fires 8
burns of all levels of severity occurring in a community 8
less severe burns 8
serious burns 8
uses of burn data 8
Epidemiology of burns in India 10
age and sex distribution 10
circumstances of injury 11
epidemiology of pediatric burns 11
etiology 10
extent of problem 10
national burns registry 10
sociocultural factors 10
Epidemiology of pediatric burns 11
Epidermal 517
Epidermal allograft culture 239
Epidermal replacement 229
Epithelialization 157
Escharectomy and delayed skin grafting 197
Escharotomy 119
principles 119
Escharotomy/fasciotomy 163
Essential criteria for skin grafting 182
Estimation of burn size 34
Etiological factors 142
Evaluate program 15
Evaluation of burn wound 153
Evaluation of success 9
Excision of burns 367
Experimental design 13
Exposure of open technique 159
Extent and part of body 517
Extent of problem 10
Eye burns 121
Eyebrow burn 359
Eyebrows 493
Eyelid and globe burn 350
F
Face burns 121
Facial burns 345
acute stage 346
management 346
management of burns in different parts of face 349
ear burn 352
eyebrow burn 359
eyelid and globe burn 350
perioral burns 357
scalp burn 358
post burn facial scarring 349
Factors affecting 51
Failure to secure intravenous lines 114
Fasciotomy 120
Fats 439
Feet burns 122
Fetal vs adult 60
Fifth degree burns 516
Fire disasters 547
Fire work/fire crackers 16
Firework and firecracker injuries 333
clinical features 336
epidemiology 335
management 340
prevention 340
types of firecrackers 334
Firework/firecracker scenario in modern times 333
First degree burns 516
clinical classification 517
full thickness burns 517
partial thickness burns 517
effects of burns 517
age 517
duration of exposure 517
extent and part of body 517
temperature 517
rule of nine classification 517
Flame burns 25
Flame injuries 269
Flammable fabrics 15
Flap cover to the deep burns of the hand 369
aftercare of burned hands 371
Flash burns 268
Flexion contractures of elbow 490
Flow phase/recovery phase 435
Fluid balance 146
Fluid therapy in burn injury 111
Foot drop or tight tendo Achilles 464
Formation of granulation tissue 157
Formation of the extracellular matrix 58
Formic acid 302
Fourth degree burns 516
Free amino acids versus intact proteins 444
Freeze drying 232
Friction burns 30, 326
epidemiology 326
etiology 327
management 330
pathogenesis 326
prevention 331
types 329
Full thickness burn wounds 118
Full thickness burns 517
Functioning of burn unit 543
Functions of skin 23, 42
Fundamentals of burn disaster planning 558
Funding 544
Fungal infection in burns 248
Fungal infections 95
Further burn wound care 173
conservative management 175
enzymatic debridement 176
modes of management 173
conservative treatment 173
deep dermal and full thickness burns 174
indeterminate depth of burns 174
superficial dermal burns 174
surgical management 173
G
Galveston formula 114
Gas gangrene and tetanus 283
Gas liquid chromatography 89
Gastrointestinal syndrome 315
General guidelines for potentially effective burn prevention activities 15
cigarette 16
crowded places (theater) 16
fire work/fire crackers 16
flammable fabrics 15
hot liquids 16
kerosene lamps and stoves 15
liquid petroleum gas leak 16
General physiotherapy of burn patients 467
Gentamicin 171
Grades of cutaneous radiation injury 319
Grading 318
Grading of burns 35
Graft maturation 193
Graft revascularization 192
Graft survival 191
Graft versus host disease 76
Grafting procedure and postgrafting care 238
Gram stain 86
H
Hair bulb 20
Hair follicle 20
Hand burns 122, 362
acute hand burns 362
anatomical considerations 362
assessment 363
initial management 364
early surgery for burns of hand 364
excision of burns 367
tangential excision 364
timing of surgery 368
Harvesting 232
Hematological 427
Hematoma 193
Hematopoietic syndrome 315
Hemoglobin and hematocrit 115
Hepatic conditions 445
Heterograft 226
High dependency area 539
Histopathology of burn wounds 43
History of burns in the ancient ages 3
Indian history 4
world history 3
History of burns in middle ages 4
Indian history 5
world history 4
History of burns in modern age 5
Indian history 6
world history 5
History of topical antimicrobial agents 166
Homograft 224
Homograft skin banking 232
cryopreservation 232
harvesting 232
rewarming 233
Hormonal therapy 446
Hot liquids 16
Hot metal burns 308
Hydrocarbons 302
Hydrofluoric acid burns 303
Hydrotherapy 165
Hydrotherapy facility 541
Hyperacute rejection 76
Hypercalcemia 140
Hyperkalemia 139, 146
Hypermetabolic stabilization phase 211
Hypernatremia 139
Hypertrophic scars and keloids 62
clinical 64
etiology 64
management 65
other potential therapies 66
prevention 65
radiation therapy 65
recent innovations 65
standard treatments 65
pathophysiology 64
surgical management of hypertrophic scars and keloids 66
excision 66
laser therapy 66
Hypocalcemia 140
Hypokalemia 139
Hypomagnesemia 140
Hyponatremia 138
Hypophosphatemia 140
Hypovolemia and oliguria 137
I
Ibuprofen 124
Identification of risk factors 425
Immediate versus gradual release 483
Immune profile of extensively burnt patient 244
Immunobiology of skin 73
mechanism of graft rejection 74 recipient in the graft 74
scientific basis of transplantation 73 behavior of transplanted tissue 74
transplantation and genetic barriers 74 immunogenic elements 74
Immunogenic elements 74
Immunologic changes 210
Immunological responses to burn injury 69
immunomodulatory therapies 70
endotoxin 70
interleukins 70
other potential immunomodulatory therapies 71
tumor necrosis factor alpha 70
immunotherapy 71
nutritional immunomodulation 71
Immunomodulatory therapies 70
Immunotherapy 71, 446
Impaired chest wall compliance 118
Impaired distal perfusion and need for escharotomy 119
Impairment and disability 527
Implement program 15
Incision versus excision 483
Indeterminate depth of burns 174
India disaster resource network 551
Indian legal enforcements 531
Indian legal scene 524
Indications for admission to hospital 394
Indications for skin grafting 182
Induction of anesthesia 214
Industrial and chemical burns 290
epidemiology 290
management 296
chemical burns 299
on site emergency care of burn victims 296
mechanism of action 291
chemical classes 292
pathophysiology 291
specific agents 301
acetic acid 301
alcohol burns 307
alkali (strong) 301
assorted acids 301
cement 301
chromic acid 302
coal tar burns 307
elemental sodium, potassium and lithium burns 305
formic acid 302
hydrocarbons 302
hydrofluoric acid burns 303
light metals 305
phenol burns 306
phosphorus burns 305
sulfur mustard gas 306
surgical treatment 309
surgical procedure 310
Ineffective immobilization 193
Infection 52, 193
Infection control program 543
Inflammatory phase 54
Information about larger populations 9
Inhalation injury management in patients without cutaneous burns 130
Initial care of burn wound 159
escharotomy/fasciotomy 163
hydrotherapy 165
management of blisters 159
biological dressings 163
dressing technique 162
exposure of open technique 159
Initial evaluation and resuscitation of burn patient 101
admission criteria 104
burn surface area assessment 104
major burn injuries 106
moderate, uncomplicated burn injuries 107
burn unit admission criteria 107
burn unit referral 106
first aid 101
chemical burns 102
electrical burns 103
thermal burns 101
inpatient management 108
outpatient wound care strategies 108
transportation 103
Initial management of burn wound 116
wound care 116
Initial management of burns involving special areas 121
ear burns 121
eye burns 121
face burns 121
feet burns 122
hand burns 122
perineal burns 122
Initial over resuscitation 114
Initial under resuscitation 114
Initiating treatment 450
Innervation of skin 23
Inpatient management 108
Instruments for grafting 183
Intake-output 115
Interaction schedule 544
Interleukins 70
Interstitial edema 40
Intralesional steroids 482
Intrinsic renal failure 144
J
Joule's law 264
K
Keratinocyte culture 235
autologous keratinocyte culture 236
biopsy 236
disadvantages 238
grafting procedure and postgrafting care 238
keratinocyte isolation 236
patient selection 236
technique of culture 236
epidermal allograft culture 239
Keratinocyte isolation 236
Keratinocyte migration 55
Keratinocyte proliferation 57
Kerosene lamps and stoves 15
L
Laboratory measurements of major burn 115
chest radiograph 116
creatinine and blood urea nitrogen 116
electrolytes 116
hemoglobin and hematocrit 115
partial thromboplastin time 116
plasma myoglobin 116
plasma proteins 116
platelets 116
prothrombin time 116
white blood cell 116
Langerhans cells 19, 77
Laser burns 30
Laser therapy 66
Late complications of inhalational injury 132
Legal requirements in managing burn patients 524
burn injuries in married female 526
criminal negligence 526
Indian legal scene 524
mode of information 525
situations 524
social civic and moral duty 524
Legal rights of burn survivors to compensation 531
Less severe burns 8
Levels of disaster 555
Light metals 305
Lightning 269
Liquid petroleum gas leak 16
Local and regional anesthesia 220
Local wound management 278
Localized exposure 316
Lund and Browder's chart 104
Lymphatic drainage of skin 23
M
Mafenide 170
Maintenance of anesthesia 215
Major burn injuries 106
Male external genitalia 505
Mallet finger 462
Management at disaster scene 560
Management of
ankle burns 453
blisters 159
burns in different parts of the face 349
burns of lower extremities 462
chest and axilla burns 452
elbow and hand burns 453
grafted axillary burn wounds 457
grafted elbow burn wounds 458
grafted neck burn wounds 456
grafted wrist burn wounds 459
hand burns 459
knee burns 453
lower limb burns 453
neck burns 451
perineal burn contractures/reconstruction 386
pruritis 482
Massage 481
Mechanical ventilation 131
Mechanism of action 291
Mechanism of graft rejection 74
Medical preparedness and mass casualty management 555
Medical research council 73
Medicolegal assessment of burn victim 519
accidental burns 520
identification 520
suicidal burns 520
Meek grafting 182
Melanocytes 19
Members of burn team 537
Mentosternal or flexion contractures of neck 486
Merkel cells 20
Meshing of graft 185
Metabolic acidosis 140
Metabolic alkalosis 141
Metabolic changes 210
Metacarpophalangeal joint contractures 372
Methods for skin storage 231
deep freezing or cryopreservation 232
freeze drying or lyophilization 232
refrigeration 231
Meticulous medical records 125
Meticulous medical records 125
Microbiology in burns 79
Microbiology in burns 79
etiology 80
pathogenesis 80
quantitative microbiology 81
significance of microbial numbers 81
significance of specific microorganisms 82
Microorganisms and their sources in burn wound contamination 242
Microvascular coagulopathy 421
Minor burns 35
Mode of application 170
Mode of information 525
Mode of injury 390
Mode of renal replacement therapy 147
Moderate burns 35
Moderate, uncomplicated burn injuries 107
Modes of feeding/nutritional support 440
Modes of management 173
Modulation of hormonal and endocrine response 428
Molten plastic burns 308
Morphine 123
Moustaches 498
Multiple organ dysfunction syndrome 243, 417
Multiple organ failure 413
N
NAC reconstruction 503
National burn mass casualty management system 566
National burns registry 10
National disaster management Act, 2005 566
National disaster management guidelines-medical preparedness and mass casualties management 554
levels of disaster 555
medical preparedness and mass casualty management 555
role of emergency operation center 556
National disaster mitigation resource centers 554
National disaster response force 553
National institute of disaster management 551
Nature of data needed to study burn epidemiology 9
burn problem 9
burn rates 9
evaluation of success 9
information about larger populations 9
prevention 9
usefulness of burn data from a single hospital 9
Neurological complications 281
Newer modes of mechanical ventilation 132
Nonexperimental descriptive study 12
Non-invasive wound infection 243
Non-pharmacological strategies 144
Nutrient requirement and dietary management 437
complications of parenteral nutrition 443
re-feeding syndrome 443
warnings and precautions for PN use 443
weaning of parenteral nutrition 443
modes of feeding/nutritional support 440
enteral nutrition by tube feeding 441
oral dietary support 440
parenteral nutrition 442
protein and energy requirements 437
calculating nutrient requirement 439
carbohydrates 438
energy 438
fats 439
proteins 439
vitamins and minerals 440
time to start nutrition 440
early versus late enteral nutrition 440
Nutrition 52, 428
Nutrition in special conditions 445
hepatic conditions 445
pulmonary conditions 445
renal conditions 445
Nutritional assessment chart 445
Nutritional immunomodulation 71
Nutritional support 147
O
Objectives of treatment 450
Objects producing burns 517
Ohm's law 264
Omniderm 227
Operation theater 541
Opsite/cling film/via film 227
Oral dietary support 440
Organization of burn unit 537
activities of burn unit 543
allograft skin bank program 543
burn prevention program 543
continuity of care program 543
infection control program 543
performance improvement program 543
research program 543
casualty 537
constructional considerations 540
design of burn unit 538
acute care area 538
convalescent care area 539
high dependency area 539
dressing room 541
environment control 540
functioning of burn unit 543
funding 544
hydrotherapy facility 541
interaction schedule 544
members of burn team 537
monitors 542
operation theater 541
physiotherapy unit 542
utilization and cost containment 542
Other microbiological methods 87
Other potential immunomodulatory therapies 71
Other potential therapies 66
Other therapeutic measures and novel therapies 145
Outpatient wound care strategies 108
Overhydration 138
Overhydration 138
Oxygen 52
Oxygenation 115
Oxygenation of tissues 156
P
Padgett-hood dermatome 184
Pain management 123
buprenorphine 123
butorphenol 124
diclofenac 124
ibuprofen 124
morphine 123
paracetamol 124
pentazocine 124
tramadol 124
Papillary dermis 21
Paracetamol 124
Paralytic ileus 40
Parameters to assess nutritional status of burn patient 436
Parenteral nutrition 442
Partial thickness burn wound 118
Partial thickness burns 517
Partial thromboplastin time 116
Pathophysiology of burn shock 37
Patient selection 236
Pediatric burns 221, 390
complications 403
first aid 392
management 393
assessment of burn injury 393
indications for admission to hospital 394
initial management 395
mode of injury 390
pathophysiology 392
prevention 403
prognosis 403
Pentazocine 124
Performance improvement program 543
Perineal burns 122, 357
Permanent skin substitutes 227
Pharmacological strategies 145
Phases in wound healing 54
fetal vs adult 60
formation of extracellular matrix 58
inflammatory phase 54
cellular response and inflammation 55
chemical mediators of inflammation 55
proliferative phase 55
angiogenesis 58
keratinocyte migration 55
keratinocyte proliferation 57
reconstitution of dermis 57
reepithelialization 55
restoration of basement membrane zone 57
remodeling phase 59
Phenol burns 306
Phosphorus burns 305
Physical dosimetry 316
Physics of electricity 264
Physiologic and metabolic responses to burn injury 434
anabolic phase 435
EBB or shock phase 435
flow phase/recovery phase 435
Physiologic measurements of major burn 115
arterial pressure 115
baseline body weight 115
blood gases 115
body temperature 115
cardiac output, mixed venous oxygen tension 115
central venous pressure 115
electrocardiographic monitoring 115
intake-output 115
oxygenation 115
pulmonary artery wedge pressure 115
urine output 115
Physiotherapy for burn patients 450
Boutonniere deformity 461
initiating treatment 450
mallet finger 462
calcaneal deformity 465
foot drop or tight tendo-Achilles 464
management of burns of lower extremities 462
valgus deformity 465
varus deformity 466
objectives of treatment 450
primary goal 450
physiotherapy in acute stage 451
ankle burns 453
chest and axilla burns 452
elbow and hand burns 453
knee burns 453
lower limb burns 453
neck burns 451
physiotherapy in later stages 454
stages of treatment 450
acute 450
follow-up 451
subacute 450
swan neck deformity 461
treatment of wounds/scars/grafts in physiotherapy 455
grafted axillary burn wounds 457
grafted elbow burn wounds 458
grafted neck burn wounds 456
grafted wrist burn wounds 459
hand burns 459
Physiotherapy in acute stage 451, 454
Physiotherapy unit 542
Pigment changes in skin following burns 61
Pinch grafts 182
Pinna 498
Piriform alveoli 20
Pitfalls in initial fluid resuscitation 114
failure to secure intravenous lines 114
initial over resuscitation 114
initial under resuscitation 114
striving for ideal numbers 114
Plasma myoglobin 116
Plasma proteins 116
Platelets 116
Plight of burn survivor 529
Polymerase chain reaction 88
Post burn contractures 473
associated local conditions in patients with contractures 474
deeper tissues 474
skin 474
contractures of axilla 489
control of wound/scar contraction and scar contracture 479
intralesional steroids 482
management of pruritis 482
massage 481
pressure garments 479
silicones 481
skin grafting 479
splintage and exercises 480
ectropion of the eyelids 486
mentosternal or flexion contractures of the neck 486
flexion contractures of the elbow 490
mechanism 473
prevention of wound/scar contraction and scar contractures 478
priority of release in cases of multiple contractures 476
surgical intervention 482
immediate versus gradual release 483
incision versus excision 483
provision of skin cover 483
release of contracture 482
timing of surgery in post burn contractures 474
wrist and knee 490
Post burn facial scarring 349
Post burn hand deformities and their management 372
amputations 378
distal interphalangeal joint problems 376
metacarpophalangeal joint contractures 372
proximal interphalangeal joint problems 375
volar contractures 378
web space problems 376
Post burn losses 491
amputations 507
breast 499
NAC reconstruction 503
reconstruction of areola 504
reconstruction of nipple 504
reconstruction of the burned breast 500
reconstruction of the mound 500
release alone versus excision-release 501
timing of NAC reconstruction 504
eyebrows 493
male external genitalia 505
moustaches 498
nose 495
pinna 498
scalp 491
Post burn scars 469
Postoperative care of graft 194
Predisposing factors 418
Pre-experimental design 13
Preparation of wound for grafting 178
Prerenal failure 143
Present and future of skin allograft 77
Pressure garments 466, 479
Prevention of burns in India 12
risk factors 12
at home 12
at play 12
at work 12
Prevention of contractures 386
Prevention of disability 532
Prevention of infection 385
Prevention of wound/scar contraction and scar contractures 478
Primary excision 197
Primary goal 450
Primary healing 53
Primary line of management 250
Primary survey 108
Principles of disaster management 566
Principles of wound management 156
debridement 156
epithelialization 157
formation of granulation tissue 157
oxygenation of tissues 156
wound contraction 158
Priority of release in cases of multiple contractures 476
Processing of wound specimens 84
Program of rehabilitation for burn patient 124
Proliferative phase 55
Protein and energy requirements 437
Proteins 439
Prothrombin time 116
Provision of skin cover 483
Proximal interphalangeal joint problems 375
Psychological disorders 513
Pulmonary artery wedge pressure 115
Pulmonary edema 146
Q
Quality and maintenance 467
Quantifying and classifying 143
Quantitative microbiology 81
Quasi-experimental design 13
R
Radiation 52
Radiation biology 314
Radiation burn 30, 313
acute radiation syndrome 315
localized exposure 316
whole-body exposure 315
basics of radiation 313
cutaneous radiation syndrome 318
grading 318
investigations 316
biological dosimetry 316
for dose estimation 316
physical dosimetry 316
medical treatment 317
radiation biology 314
radiation injuries 314
radiation units 314
surgical management 324
types of accident 313
Radiation injuries 314
Radiation protection programs 324
Radiation therapy 65
Radiation units 314
Recent innovations 65
Recipient in the graft 74
Reconstitution of the dermis 57
Reconstruction of
areola 504
burned breast 500
mound 500
nipple 504
Reconstructive phase 217
Re-feeding syndrome 443
Refrigeration 231
Rehabilitation council of India Act, 1992 532
Rehabilitation issues in hand burns 380
Reinnervation of graft 193
Release alone versus excision-release 501
Release of contracture 482
Remodeling phase 59
Renal and hepatic 428
Research designs for burn prevention 12
experimental design 13
purpose 13
tasks 13
nonexperimental descriptive study 12
purpose 12
tasks 12
pre-experimental design 13
cautions 13
purpose 13
tasks 13
quasi-experimental design 13
purpose 13
tasks 13
Research program 543
Resistance 264
Respiratory 427
Respiratory acidosis 141
Respiratory complications of smoke inhalations 129
Respiratory system changes 209
Respiratory tract injury in burns 127
clinical features 128
diagnosis 128
grade features 129
respiratory complications of smoke inhalations 129
management 130
carbon monoxide poisoning 132
cyanide poisoning 133
inhalation injury management in patients without cautaneous burns 130
late complications of inhalational injury 132
mechanical ventilation 131
newer modes of mechanical ventilation 132
weaning and discontinuation of mechanical ventilation 132
pathogenesis 127
pathophysiology 128
Restoration of the basement membrane zone 57
Resuscitation phase 210
Reticular dermis 21
Rewarming 233
Role of albumin in burns 446
Role of early physiotherapy 449
Role of environmental and clinical factors 448
Role of immunonutrition/immunomodulators in burns and critically ill patients 448
Role of the emergency operation center 556
Rule of nine classification 517
S
Sample transport 84
Scald burns 26
Scalp 283, 491
Scalp burn 358
Scientific basis of transplantation 73
Scoring 422
Sebaceous glands 20
Second degree burns 516
Secondary excision 197
Secondary healing 53
Secondary line of management 251
Secondary survey 111
Sepsis 417
balancing oxygen supply and demand 426
control of inflammatory stimuli 426
etiopathology 418
immunotherapy 428
management 425
nutrition 428
pathogenesis 419
dysregulated apoptosis 421
microvascular coagulopathy 421
tissue hypoxia 420
uncontrolled infection 419
uncontrolled systemic inflammation 419
predisposing factors 418
prevention 425
identification of risk factors 425
scoring 422
specific organ support 427
cardiovascular system 427
hematological 427
renal and hepatic 428
respiratory 427
specific therapeutic interventions 428
modulation of hormonal and endocrine response 428
Sepsis syndrome 243
Septicemia 243
Sequence of tasks for burn prevention programs 14
consider possible strategies 14
design the intervention 15
document the problem 14
evaluate program 15
implement program 15
Sequential excision 197
Sequential system failure 413
Serious burns 8
Serum cystatin C 144
Severely burned ICU patients 447
SGOT 298
SGPT 298
Sheet grafting 182
Sick cell syndrome 138
Significance of microbial numbers 81
Significance of specific microorganisms 82
Silicones 481
Silver nitrate solution 169
Silver sulfadiazine 168
Sixth degree burns 516
Skin allograft rejection and acceptance 75
Skin grafting 479
Skin grafting of burn wound 177
application of graft 188
complications of skin grafting 193
hematoma 193
ineffective immobilization 193
infection 193
delayed application of graft 190
donor areas 183
dressing change 190
blood loss from donor areas 190
essential criteria for skin grafting 182
graft survival 191
graft maturation 193
graft revascularization 192
reinnervation of graft 193
indications for skin grafting 182
instruments for grafting 183
meshing of graft 185
advantages 186
disadvantages 188
postoperative care of graft 194
preparation of wound for grafting 178
technique of harvesting split skin graft 185
types of skin grafts 181
based on size and technique 182
based on the anatomy 181
based on thickness 181
wound swabs 180
Skin substitutes in burns 223
composite epidermal and dermal replacement 229
epidermal replacement 229
cultured allogenic keratinocytes 229
cultured keratinocytes 229
permanent skin substitutes 227
dermal replacement— biological 228
dermal replacement—synthetic 227
temporary skin substitutes (synthetic) 226
apligraf 227
biobrane 226
omniderm 227
opsite/cling film/via film 227
transcyte 227
temporary skin substitutes biological 223
amniotic membrane 223
collagen 224
heterograft 226
homograft 224
Social civic and moral duty 524
Sources of burn data 8
Specific agents 301
Specific organ support 427
Specific therapeutic interventions 428
Splint selection 466
Splintage and exercises 480
Stages of treatment 450
Stamp grafts 182
Standard coding of burn injury data 8
Standard treatments 65
Steroids 52
Stratum basale 19
Stratum corneum 18
Stratum granulosum 18
Stratum lucidum 18
Stratum spinosum 18
Striving for ideal numbers 114
Subfascial excision 197
Suicidal burns 520
Sulfur mustard gas 306
Superficial dermal burns 174
Supportive treatment 146
Suppurative thrombophlebitis 258
tetanus in burns 258
tetanus prophylaxis 258
treatment of tetanus in burns 259
Suprafascial full thickness excision 197
Surge capacity of health care units 557
Surgical management of hypertrophic scars and keloids 66
Swan neck deformity 461
Sweat glands 21
Systemic antibiotic use and its guidelines 90
Systemic inflammatory response syndrome 417, 243, 423
T
Tangential excision 197, 200, 364
Technique of culture 236
Technique of harvesting split skin graft 185
Technique of tangential excision 201
Temperature 517
Temporary skin substitutes 226
synthetic 226
biological 223
Tertiary line of management 252
Tetanus in burns 258
Tetanus prophylaxis 258
Thermal burns 25, 101
Thermal contact burn 27
Third degree burns 516
Time to start nutrition 440
Timing of NAC reconstruction 504
Timing of surgery in post burn contractures 474
Tissue hypoxia 420
Topical antimicrobial therapy in treatment of burn wound 166
bacitracin 171
basis for topical therapy 167
criteria for a good antimicrobial agent 167
gentamicin 171
advantages 171
disadvantages 171
mode of action 171
history of topical antimicrobial agents 166
mafenide 170
advantages 170
disadvantages 170
mode of application 170
silver nitrate solution 169
advantages 169
disadvantages 169
mode of action 169
silver sulfadiazine 168
advantages 168
disadvantages 168
mode of action 168
Topical therapy 89
Tramadol 124
Transcyte 227
Transplantation and genetic barriers 74
Transportation 103
Treatment of tetanus in burns 259
Treatment of wounds/scars/grafts in physiotherapy 455
Triage 559
Triage criterion and care plan 563
True electrical injury 268
Tumor necrosis factor alpha 70
Type of current 264
Types of accident 313
Types of burn wound excision 197
Types of electrical injuries 268
Types of firecrackers 334
Types of organisms 243
Types of primary excision 197
Types of rejection 76
accelerated acute rejection 76
acute rejection 76
chronic rejection 76
hyperacute rejection 76
Types of skin grafts 181
based on size and technique 182
based on the anatomy 181
based on thickness 181
Types of splints 466
pressure garments 466
dependency exercise 467
duration of use 467
quality and maintenance 467
splint selection 466
U
Uncontrolled infection 419
Uncontrolled systemic inflammation 419
Unit of current 264
Upper extremity and lower extremity 284
Urinary diversion 385
Urinary indices 144
Urine output 115
Urine volume 144
Usefulness of burn data from a single hospital 9
Uses of burn data 8
Utilization and cost containment 542
Utilization of medical triage 559
communications 560
district control rooms 560
emergency operations center 560
management at disaster scene 560
triage 559
V
Valgus deformity 465
Varus deformity 466
Vascular access 147
Viral infection in burns 248
Viral infections 95
Vitamins and minerals 440
Vitamins and trace elements 52
Volar contractures 378
Voltage 264
Vulnerability assessment and risk analysis 549
W
Wallace's rule of ‘nine’ 104, 393
Warnings and precautions for PN use 443
Watson's modification 184
Watson's skin grafting knife 184
Weaning and discontinuation of mechanical ventilation 132
Weaning of parenteral nutrition 443
Web space problems 376
White blood cell 116
White graft rejection 75
Whole-body exposure 315
Wilson's classification 517
deep 517
dermoepidermal 517
epidermal 517
World history 3, 4, 5
Wound care 116
Wound contraction 158
Wound evaluation 153
Wound fluid sampling 83
Wound healing in burns 51
factors affecting 51
age 51
chemotherapeutic agents 52
infection 52
nutrition 52
oxygen 52
radiation 52
steroids 52
vitamins and trace elements 52
general 52
types 53
primary healing 53
secondary healing 53
Wound management 385
Wound swabs 180
Wound tissue sampling methods 83
Wound-sampling methods 83
Wrist and knee 490
×
Chapter Notes

Save Clear


1Principles and Practice of Burn Care2
3Principles and Practice of Burn Care
Editor-in-Chief Sujata Sarabahi MS MCh DNB MNAMS Assistant Professor and Specialist Plastic Surgeon Department of Burns, Plastic, Maxillofacial and Microvascular Surgery Vardhman Mahavir Medical College and Associated Safdarjung Hospital, New Delhi, India Editors VK Tiwari MS MCh Professor and Senior Specialist Plastic Surgeon Department of Burns, Plastic, Maxillofacial and Microvascular Surgery, Vardhman Mahavir Medical College and Associated Safdarjung Hospital, New Delhi, India Arun Goel MS MCh FICS Senior Specialist Plastic Surgeon and Head of Unit Department of Burns, Plastic, Maxillofacial and Microvascular Surgery, Lok Nayak Hospital and Associated Maulana Azad Medical College, New Delhi, India LC Gupta MD (Radiology) DMRE MD (PSM) FAMS DSc (Hon.) Retd. Director Medical, Border Security Force, India
4Published by
Jitendar P Vij
Jaypee Brothers Medical Publishers (P) Ltd
Corporate Office
4838/24 Ansari Road, Daryaganj, New Delhi - 110002, India, Phone: +91-11-43574357, Fax: +91-11-43574314
Registered Office
B-3 EMCA House, 23/23B Ansari Road, Daryaganj, New Delhi - 110 002, India
Phones: +91-11-23272143, +91-11-23272703, +91-11-23282021
+91-11-23245672, Rel: +91-11-32558559, Fax: +91-11-23276490, +91-11-23245683
Branches
North America Office
1745, Pheasant Run Drive, Maryland Heights (Missouri), MO 63043, USA Ph: 001-636-6279734
Central America Office
Jaypee-Highlights Medical Publishers Inc., City of Knowledge, Bld. 237, Clayton, Panama City, Panama Ph: 507-317-0160
Principles and Practice of Burn Care
© 2010, Jaypee Brothers Medical Publishers (P) Ltd.
All rights reserved. No part of this publication should be reproduced, stored in a retrieval system, or transmitted in any form or by any means: electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the editors and the publisher.
First Edition: 2010
9788184488098
Typeset at JPBMP typesetting unit
Printed at
5
To
My Parents who Made me What I am Today
To
My Husband whose Constant Moral Support Gave me The Base on Which I Worked
To
My Children, Rohan and Arushi whose Patience and Love Helped me to Continue
To
My Father in Law who Inspired me To Write this Book and his Constant Encouragement Helped me Finish the Book
To
My Mother in Law whose Support Enabled me to Undertake this Venture and last but not the least To My Sister for her Love and Encouragement
6
7Contributors 11Foreword
It gives me a great pleasure to write a foreword for this book entitled Principles and Practice of Burn Care, which has been ably compiled and edited by Dr Sujata Sarabahi, Dr VK Tiwari, Dr Arun Goel and Dr LC Gupta.
Sufferings of the World Wars have given some precious dividends of today. Efforts and contributions of Sir Harrold Gillies in various fields of Plastic Surgery including his invaluable contributions in burns outshine till this day. The unfortunate victims of burns are crippled, deformed, handicapped and disfigured and socially unacceptable. These poor patients are shoved into dark and smelly corners of the surgical wards of hospitals and left to die or scar in their own serum and sepsis. Being treated at general hospitals without skin grafting, most of them land up with horrible deformities and scars.
The magnitude of problem in a developing country like ours is a colossal challenge. We still do not have a central burn registry, which means that the magnitude of the problem is yet not fully understood, appreciated and defined. National Academy of Burns—India (NABI) conducted a survey over several years and found that about 7 million (70 lakhs) people get burnt annually, 7 lakhs need hospital admission, 2.5 lakhs get crippled with deformities and 1.4 lakhs die annually. The facilities for treatment are from meager to non-existent in some parts of the country. The progress has been no happy fluke, but a personal response to the challenge by a very few in the country. The research of some workers on the physiology and pathology of this trauma has given us valuable new insights; others have had the vision to see how new understandings could be translated into useful techniques, while yet others have responded to the clinical challenge by commitment of their lives to the delivery of burn care and to burn prevention.
Historically speaking, the first dedicated burn unit was started in India under my guidance in the Department of Burns, Plastic and Maxillofacial surgery at Safdarjung Hospital, New Delhi in 1963 and this department went on to become the largest burn care unit in Asia. This unit has been an example of commitment and dedication to the cause of optimum burn care in the country. Over the years, the details of treatment have been changing and facilities improved and advanced with progress in the world by various subsequent heads of the department. It is a matter of great pride that this book also comes from the same department where the story started in a barrack of a hospital designed for wartime casualties. The journey for this department has been long and arduous and I am happy to say that it has enjoyed the status of excellence all this while.
The editors are to be congratulated on recording in this volume entitled Principles and Practice of Burn Care, the views of several authors covering the entire country. This book has been divided into 7 sections, depending on the various situations in managing burns and has contributions from eminent specialists involved in burn care and research. Each section has chapters relevant to clinical management of the burn patient. The book is comprehensive and yet makes for easy reading. I am sure the students and doctors will find here the important practical information they need to give safe and thorough care to their burn patients.
I also hope that this book will be used in other developing countries especially by those who work in peripheral district hospitals and private medical practitioners with limited means. The basic essential to start a unit, is to have a committed staff who are ready to be spent for the sake of those in their care. The book will provide them with knowledge they need.
I wish this book a great success.
JL Gupta
Consultant in Burns, Plastic and Maxillofacial Surgery,
Formerly, Head of Department of Burns, Plastic and Maxillofacial Surgery, Safdarjung Hospital, New Delhi
Professor of Plastic Surgery, University of Delhi
Patron, National Academy of Burns – India
12
13Preface
Burns is the most serious injury ever inflicted on mankind. This appears to be the price of civilization which man is paying today. India is amongst the few countries of the world where the incidence of burns is showing a rising trend even though it is on the decline in the Western world. Management of burns is difficult and time consuming. Apart from being a costly treatment, it is also a heart-breaking experience for any specialist treating a burn victim and rehabilitating him back to the society is equally difficult.
Over the centuries, we have discovered how to use new technological innovations and scientific advances to the greater advantage of victims of burns, fire, bomb blast and other terrorist crimes. However, in view of the continuously changing circumstances, it becomes imperative for burn surgeons, physicians and other para-medicals to constantly learn to change and accept changes and keep themselves updated at all the times with the new skills and techniques in the management of burn patients. We cannot afford to remain silent, inactive or resilient even in the treatment of minor accidental burn cases which otherwise receive scant attention by the hospital staff possibly because they are not dangerous to life or due to lack of interest on their part.
In the 21st century we are learning to evaluate new products and technologies more realistically. In short we are re-discovering the wisdom of our ancestors and learning to value the efforts made by others so far in modifying and improving our methods and skills in burn care. Regular studies and continuous research in various fields have proven to be the right investment in improving every aspect of human life—so why not for burn injury?
Though a burn specialist treats burn patients, but the modern treatment of major burns depends upon multidisciplinary team approach which includes anesthetist, medical specialist, pulmonologist, nutritionist, physiotherapist and occupational therapist. Each of them helps in providing a holistic approach towards treating and rehabilitating a burn patient.
This book brings together the knowledge and clinical experience of many of the specialists from all over the country, who have made outstanding contributions in the field of burn care. An attempt has been made to deliver comprehensive information about the treatment of a burn victim in all its aspects from the experiences and expertise of these surgeons and physicians serving in the battlefield of burns, i.e The Burn Units; thus gaining and giving opportunities to learn from the best. This book emphasizes not only on the treatment and rehabilitation of burns but also the pathophysiology of burns and its prevention. It was not an easy task and required constant follow up to get others associated in producing this book.
I am thankful to all the contributors who are experts in their own fields for sharing their knowledge and experiences which have been reflected in their contributions, which I am sure will be beneficial to all the postgraduate and practicing burn surgeons who will be reading this book.
I have personally inserted photographs of many interesting cases in various chapters in addition to the photographs provided by the contributors in order to make the topic more interesting and easy to comprehend.
A book of this magnitude cannot be brought out single handedly. Dr Arun Goel, Dr VK Tiwari and Dr LC Gupta have been associated in editing this book and their help and support cannot be acknowledged in words. Without them, it would not have been possible to bring out this book which is complete in every sense, whether it is in the text content, pictorial depiction or practical case management protocol.
I am grateful to Dr SP Bajaj, who has been my guide and a father figure in burn management in India, for his valuable suggestions and encouragement at every step.
I am also thankful to my residents specially Dr Jeethendran Iyer for providing help in procuring the case photographs and Dr Geetika Khanna for providing the histological slides.
14
I must especially thank my publisher M/s Jaypee Brothers Medical Publishers (P) Ltd. especially Shri Jitendar P Vij (Chairman and Managing Director), Mr Tarun Duneja (Director, Publishing) for having recognized the merits of the presented material and to have come forward enthusiastically for publishing the book.
Lastly, I am thankful to my family for their moral support in helping me complete this book.
JAI HIND and Good Luck to my readers whoever and wherever they are.
Sujata Sarabahi