Stem Cells Eapen Cherian, G Nandhini, Anil Kurian
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1Stem Cells2
3Stem Cells
Eapen Cherian MDS Reader Department of Oral Pathology and Forensic Odontology Pushpagiri College of Dental Sciences Thiruvalla, Kerala, India Co-authors G Nandhini MDS Senior Lecturer Department of Oral and Maxillofacial Pathology SRM Dental College Chennai, Tamil Nadu, India Anil Kurian BDS PGDCR Researcher Department of Oral Pathology and Forensic Odontology Pushpagiri College of Dental Sciences Thiruvalla, Kerala, India Foreword K Rajkumar
4
Published by
Jaypee Brothers Medical Publishers (P) Ltd
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Stem Cells
© 2011, Jaypee Brothers Medical Publishers
All rights reserved. No part of this publication should be reproduced, stored in a retrieval system, or transmitted in any form or by any means: electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the authors and the publisher.
This book has been published in good faith that the material provided by authors is original. Every effort is made to ensure accuracy of material, but the publisher, printer and authors will not be held responsible for any inadvertent error(s). In case of any dispute, all legal matters are to be settled under Delhi jurisdiction only.
First Edition : 2011
9789350250600
Typeset at JPBMP typesetting unit
Printed in India
5Dedicated to
My Dear Family6
7Foreword
It is a privilege to write a foreword for the book titled Stem Cells authored by Dr Eapen Cherian, Reader, Department of Oral Pathology and Forensic Odontology, Pushpagiri College of Dental Sciences, Thiruvalla, Kerala, India and co-authored by Dr G Nandhini, Senior Lecturer, Department of Oral and Maxillofacial Pathology, SRM Dental College, Chennai, Tamil Nadu, India and Dr Anil Kurian, Researcher, Department of Oral Pathology and Forensic Odontology, Pushpagiri College of Dental Sciences, Thiruvalla, Kerala, India.
Stem cells are such a fascinating field in science with tremendous scope to dramatically change the treatment of human diseases. Every organ and tissue is made up of specialized cells that originate from a pool of stem cells. Stem cells play a vital role in regenerating organs and tissues that are injured or lost every day, such as our skin, hair, blood and the lining of our gut. Knowledge about stem cells is central to understanding not just normal development, but also human disease and injury, and for using this knowledge to develop new therapies.
This textbook provides a comprehensive and complete review of what you need to know about stem cells. This book will not only serve as a source of information to the scientific fraternity, but also to the general public. The authors have made every attempt to make it an excellent compilation.
I wish them all success in their endeavors.
K Rajkumar BSc MDS
Professor and Head
Department of Oral and Maxillofacial Pathology and Microbiology
Editor-in-Chief, STREAMDENT—SRM University Journal of Dental Sciences
SRM Dental College, Ramapuram, Chennai
Tamil Nadu, India8
9Preface
It is with immense pleasure and satisfaction that I present the first edition of Stem Cells to students, researchers and practitioners in the medical arena.
The subject Stem Cells has assumed the status of a specialty only recently. With the rapid growth of this evolving subject, I felt the need for a book presenting all relevant information currently available; comprehensive enough to present relevant facts to the searching mind. Currently, very few books have been written with the objective to present this subject to researchers of the medical field.
It is hoped that this book will be a useful asset to fulfil the need of medical researchers in their quest to experiment into the ever dynamic opportunity that the world of Stem Cells present.
Eapen Cherian10
11Acknowledgments
I would like to acknowledge with gratitude to my co-authors Dr G Nandhini and Dr Anil Kurian for the valuable contributions they have made in successfully completing this book. I gratefully acknowledge the encouragement and advice of my beloved teacher and mentor Prof Dr K Rajkumar, Head, Department of Oral and Maxillofacial Pathology and Microbiology, SRM Dental College, Chennai, Tamil Nadu, India and also for his valuable and constant support in all my professional endeavors throughout my life. I must acknowledge Dr Oommen Aju Jacob, Principal, Pushpagiri College of Dental Sciences, Thiruvalla, Kerala, India for his help in evaluating this book and making me to realize my potential. I also thank Prof Dr Alex K Varghese, Head, Department of Oral Pathology and Microbiology, Pushpagiri College of Dental Sciences for inspiring and encouraging me during the preparation of this book.
I also record my sincere gratitude to Dr Lizamma Alex, Vice Principal, Pushpagiri Institute of Medical Sciences, for her painstaking effort in correcting this work. In this connection, I would like to thank Dr Anuja Mathews, Lecturer, Pushpagiri College of Dental Sciences and my friends Dr Ramyamalini, Senior Lecturer, SRM Dental College, Dr Sudheerkanth, Senior Lecturer, Army College of Dental Sciences, Secunderabad, Andhra Pradesh, India for their constant support.
Rev Fr Philip Payyampallil, Director, Pushpagiri Medicity and Rev Fr Mathew Mazhuvancheryil, Director, Pushpagiri Research Centre deserve special mention for encouraging the publication of this book.
I would like to thank my family for their constant support.
Above all, I thank God Almighty for making me what I am and helping me to have achieved what I have achieved.