Pharmacological Classification of Drugs with Doses and Preparations KD Tripathi
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1Pharmacological CLASSIFICATION OF DRUGS with Doses and Preparations
2Pharmacological CLASSIFICATION OF DRUGS with Doses and Preparations
fourth Edition
KD Tripathi MD Ex-Director-Professor and Head of Pharmacology Maulana Azad Medical College and associated LN and GB Pant Hospitals New Delhi
3Published by
Jitendar P Vij
Jaypee Brothers Medical Publishers (P) Ltd
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Pharmacological Classification of Drugs with Doses and Preparations
© 2010, KD Tripathi
All rights reserved. No part of this publication should be reproduced, stored in a retrieval system, or transmitted in any form or by any means: electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the author and the publisher.
This book has been published in good faith that the material provided by author is original. Every effort is made to ensure accuracy of material, but the publisher, printer and author will not be held responsible for any inadvertent error(s). In case of any dispute, all legal matters are to be settled under Delhi jurisdiction only.
First Edition: 1986
Second Edition: 1990
Third Edition: 2006
Fourth Edition: 2010
9789350250785
Typeset at JPBMP typesetting unit
Printed at Ajanta Offset
4Preface
A systematized listing of drugs according to their primary actions, mechanisms, chemical nature, clinical uses and/or other characterstics is the first step to learn about them. The mental exercise to prescribe a drug for a patient starts with identifying the class of drugs to be prescribed and then selecting the specific member most appropriate for that patient according to its subclass/group/individual characteristic. For example, the first thing one decides is whether an analgesic or an antihypertensive or an antibiotic is to be prescribed; then proceeds to consider which type of analgesic (opioid/nonopioid), or antihypertensive (β blocker/ACE inhibitor, etc.), or antibiotic (β-lactam/fluoroquinolone, etc.) is required and then which specific member is most suitable. On the other hand, every drug is known by its class and subclass, e.g. furosemide is a high-ceiling diuretic, glibenclamide is a sulfonylurea antidiabetic. Thus, the importance of grouping and compartmentalizing drugs cannot be over-emphasized. The phenomenal increase in the number of drugs in recent years has further underscored the need for drug classifications.
However, drug classifications have been criticised for being arbitrary and imperfect because of nonuniform criteria often adopted and frequent lack of watertight distinctions among drugs of different subgroups. Nevertheless, basing on pharmacological differences and applying practical criteria, meaningful drug classifications 5can be devised. Though, any drug has multiple actions/properties, it can be designated by the most outstanding one. For example, labelling atenolol as a cardioselective β blocker summarises its actions, uses, etc. This booklet has adopted such a pragmatic approach and presented classifications of drugs which have been accepted by a wide section of professionals/students dealing with drugs. The present edition has been thoroghly revised and updated to include drugs marketed till Dec. 2009.
To be useful to medical/pharmacy students as well as to practitioners, the doses (including pediatric doses wherever relevant), frequency and route(s) of administration along with leading brand names of drugs and different types of dosage forms (oral, parenteral, topical, etc.) are listed distinctively after each class of drugs. Thus, essential prescribing information has been incorporated. Single drug formulations are mainly mentioned. Combined drug formulations find a place wherever important or relevant. The listing of brand names is restricted to only 1–4 per drug, and is not exhaustive. Synonyms and alternative names of drugs and classes of drugs are also mentioned. Two separate indices, one of nonproprietary (generic) names and the other of proprietary (brand) names of drugs have been provided for ready reference.
It is hoped that the booklet will coutinue to serve as an aid to remembering drug names, knowing about them, and prescribing them correctly. The credit for meticulous production of this booklet goes to the staff of M/s Jaypee Brothers.
K.D. Tripathi
New Delhi
6th April 2010
6Explanatory Notes
  1. The proprietary (brand) names appear in capital letters. The information on dosage form(s) is printed in maroon colour.
  2. The doses and regimens are given in smaller type, while nonproprietary (generic) names appear in bigger type.
  3. If no brand name of a drug is listed, it is not currently marketed in India, or is marketed only in combinations. This can be found out from the composition of the combined formulations given.
  4. If the route of administration is not specified, the drug is administered only orally, and the dose mentioned is the oral dose.
  5. Drug doses mentioned without specifying frequency of administration indicate the quantity for a single dose.