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Recent Advances in Pediatrics (RAP): Hot Topics in General/Miscellaneous PediatricsVol 19 (2009), Vol 18 (2008), Vol 17 (2007), Vol 16 (2006), Vol 15 (2005), Vol 14 (2004), Vol 13 (2003), Vol 12 (2002), Vol 11 (2001), Vol 10 (2000), Vol 9 (1999), Vol 8 (1998), Vol 7 (1997), Vol 6 (1996), Vol 5 (1995), Vol 4 (1994), Vol 3 (1993), Vol 2 (1992), Vol 1 (1991)
- Recent Advances in Pediatrics (RAP): Special VolumesRAP Special Vol 20 : Nutrition, Growth and DevelopmentRAP Special Vol 19 : Developmental and Behavioral PediatricsRAP Special Vol 18 : Pediatric NeurologyRAP Special Vol 17 : AdolescenceRAP Special Vol 16 : Pediatric CardiologyRAP Special Vol 15 : NephrologyRAP Special Vol 14 : Critical Care PediatricsRAP Special Vol 13 : Pediatric EndocrinologyRAP Special Vol 12 : Neonatal EmergenciesRAP Special Vol 11 : Community PediatricsRAP Special Vol 10 : PulmonologyRAP Special Vol 9 : NeurologyRAP Special Vol 8 : Emergency PediatricsRAP Special Vol 7 : HematologyRAP Special Vol 6 : Gastroenterology, Hepatology and NutritionRAP Special Vol 5 : Neonatology - 2RAP Special Vol 4 : NeonatologyRAP Special Vol 3 : Tropical Pediatrics - 2RAP Special Vol 2 : Tropical PediatricsRAP Special Vol 1 : Nutrition, Growth and Development
- Recent Advances in Pediatrics (RAP) Volumes in PipelineRAP 20: Hot Topics (General/Miscellaneous Pediatrics)RAP Special Vol 22: Immunity, Infection and Immunization
- The Short Textbook of Pediatrics, 11th edition, 2009
- Differential Diagnosis in Pediatrics, 5th edition, 2009
- Instructive Case Studies in Pediatrics, 5th edition, 2011
- Pediatric Drug Directory, 8th edition, 2011
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Recent Advances in Pediatrics—Special Volume 21: Neonatal and Pediatric Intensive Care
© 2011, Shamma-Bakshi Gupte, Executive Editor
All rights reserved. No part of this publication should be reproduced, stored in a retrieval system, or transmitted in any form or by any means: electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the editors and the publisher.
First Edition: 2011
9789350251409
Typeset at JPBMP typesetting unit
Printed at
5To
Our dear parents
whose inspiration, motivation, blessings and moral support continue to contribute a great deal to our academic endeavors
and
everybody striving to contribute to child health and welfare for a brighter future globally
7CONTRIBUTORS
- Mark C Abu
- Consultant in Pediatric Neurology
- Institute of Child Health
- Bristol, United Kingdom
- Ch 30: Acute Bacterial Meningitis
- A Avinash
- Resident
- Department of Pediatrics
- Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)
- Puducherry, India
- Ch 3: Neonatal Ventilation
- Vineet Bhandari
- Associate Professor
- Division of Neonatal-Perinatal Medicine
- Department of Pediatrics
- Yale School of Medicine
- New Haven, Connecticut, United States
- Ch 5: Meconium Aspiration Syndrome
- B Vishnu Bhat
- Director-Professor
- Department of Pediatrics
- Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)
- Puducherry, India
- Ch 3: Neonatal Ventilation
- Ch 9: Surfactant Therapy
- Ch 10: Neonatal Sepsis
- Ch 19: Retinopathy of Prematurity
- Ch 24: Pneumonia
- Douglas Burrin
- Associate Professor
- Department of Pediatrics
- Baylor College of Medicine
- Houston, Texas, United States
- Ch 12: Neonatal Necrotizing Enterocolitis
- JP Dadhich
- Visiting Consultant Neonatologist
- Department of Pediatrics
- SL Jain Hospital
- Delhi, India
- Ch 1: Neonatal Resuscitation
- SS Dayal
- Associate Professor
- Department of Pediatrics and Neonatology
- Command Hospital (Air Force)
- Bangalore, India
- Ch 13: Nosocomial Infections in the NICU
- Ch 16: Neonatal Hypoglycemia
- Pooja Dewan
- Lecturer
- Department of Pediatrics
- University College of Medical
- Sciences (UCMS) and Guru Teg Bahadur Hospital
- Delhi, India
- Ch 22: Status Epilepticus
- Sourabh Dutta
- Additional Professor
- Newborn Unit
- Department of Pediatrics
- Postgraduate Institute of Medical Education and Research (PGIMER)
- Chandigarh, India
- Ch 21: Feeding Low Birth Weight Neonates
- Tarun Gera
- Consultant
- Department of Pediatrics
- SL Jain Hospital
- Delhi, India
- Ch 1: Neonatal Resuscitation
- Ajay Gaur
- Associate Professor
- Department of Pediatrics
- GR Medical College
- Gwalior, MP, India
- Ch 2: Post-Resuscitation Care
- Arun Gopalakrishnan
- Resident
- Department of Pediatrics
- Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)
- Puducherry, India
- Ch 19: Retinopathy of Prematurity
- H Gopakumar
- Senior Fellow in Neonatology
- Amrita Institute of Medical Sciences (AIMS)
- Kochi, Kerala, India
- Ch 17: Neonatal Seizures
- K Gowrinath
- Professor and Head
- Department of Pulmonary Medicine
- Narayana Medical College and Hospital
- Nellore, AP, India
- Ch 26: Acute Exacerbation of Asthma
- Neeraj Gupta
- Registrar
- Division of Pediatrics
- St Stephens Hospital
- Delhi, India
- Ch 4: CPAP Technology: Where Affordability Meets Utility
- Ravinder K Gupta
- Associate Professor
- Department of Pediatrics
- Acharya Shri Chandar College of Medical Sciences (ASCOMS)
- Sidhra, Jammu, Jammu and Kashmir
- India
- Ch 25: Approach to a Child with Burns
- Ch 27 : Diabetic Ketoacidosis
- Ritu Gupta
- Lecturer
- Department of Physiology
- Government Medical College
- Jammu, Jammu and Kashmir
- India
- Ch 25: Approach to a Child with Burns
- Ch 27: Diabetic Ketoacidosis
- Suraj Gupte
- Professor and Head
- Postgraduate Department of Pediatrics
- Narayana Medical College and Hospital
- Nellore, AP, India
- Ch 11: Neonatal Meningitis
- Ch 30: Acute Bacterial Meningitis
- Abbas Hyderi
- Clinical Associate
- Division of Neonatal-Perinatal Medicine
- Department of Pediatrics
- University of Calgary
- Alberta, Canada
- Ch 6: Hypoxic-Ischemic Encephalopathy
- Sunil Jain
- Assistant Professor
- Division of Neonatology
- Department of Pediatrics
- Galveston, Texas, United States
- Ch 12: Neonatal Necrotizing Enterocolitis
- Manas Kalra
- Pediatric Hematology, Oncology and Bone Marrow Transplantation Unit
- Sir Ganga Ram Hospital
- New Delhi, India
- Ch 28: Severe Anemia
- Sakshi Karkra
- Clinical Assistant
- Department of Pediatric
- Gastroenterology and Hepatology
- Sir Ganga Ram Hospital
- Delhi, India
- Ch 31: Gastrointestinal Bleeding
- David R Kelly
- Clinical Professor of Pathology
- University of Alabama at Birmingham
- Pathologist-in-Chief and Medical
- Director of Laboratories
- Children's Hospital of Alabama
- Birmingham, Alabama, United States
- Ch 12: Neonatal Necrotizing Enterocolitis
- M Sunil Sai Kishore
- Newborn Unit
- Department of Pediatrics
- Postgraduate Institute of Medical Education and Research (PGIMER)
- Chandigarh, India
- Ch 21: Feeding of Low Birth Weight Neonates
- Anjali Kulkarni
- Consultant Neonatologist
- Academic Coordinator
- Apollo Centre for Advanced Pediatrics
- Indraprastha Apollo Hospital
- New Delhi, India
- Ch 8: Respiratory Distress Syndrome
- Ch 15: Neonatal Shock
- Renu Kumar
- Assistant Professor (Ex)
- Department of Pediatric Surgery
- Narayana Medical College and Hospital
- Nellore, AP, India
- Ch 7: The Newborn with Respiratory Distress: Surgical Aspects
- Ch 32: Acute abdomen
- Manish Kumar
- Senior Resident
- Department of Pediatrics
- Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)
- Puducherry, India
- Ch 10: Neonatal Sepsis
- RP Kudyar
- Professor
- Department of Pediatrics
- Acharya Shri Chandar College of Medical Sciences (ASCOMS)
- Sidhra, Jammu, J and K, India
- Ch 27: Diabetic Ketoacidosis
- Jaikrishan Mittal
- Senior Consultant Neonatology
- Fortis Hosptial, Jaipur
- Ch 20: Analgesia and Sedation in Newborn
- Akhil Maheshwari
- Assistant Professor
- Divisions of Neonatology and Pediatric Gastroenterology
- Departments of Pediatrics, Cell Biology, and Pathology
- University of Alabama at Birmingham
- Birmingham, Alabama, United States
- Ch 12: Neonatal Necrotizing Enterocolitis
- Yogangi Malhotra
- Fellow
- Division of Neonatal-Perinatal Medicine
- Department of Pediatrics
- Yale School of Medicine
- New Haven, Connecticut, United States
- Ch 5: Meconium Aspiration Syndrome
- Neelam Mohan
- Consultant Pediatric
- Gastroenterologist, Hepatologist
- Therapeutic Endoscopist and Liver Transplant Physician Centre for Child Health
- Sir Ganga Ram Hospital, New Delhi
- Ch 31: Gastrointestinal Bleeding
- Nancy Nelson
- Assistant Professor of Neonatology
- University School of Medicine
- Philadelphia, United States
- Ch 11: Neonatal Meningitis
- Rajniti Prasad
- Senior Lecturer
- Department of Pediatrics
- Institute of Medical Sciences
- Banaras Hindu University
- Varanasi, UP, India
- Ch 23: Acute Bronchiolitis
- Ch 29: Comatose Child
- Jacob M Puliyel
- Head
- Division of Pediatrics
- St Stephens Hospital
- Delhi, India
- Ch 4: CPAP Technology: Where Affordability Meets Utility
- Vinayan Puthenveettil
- Clinical Professor
- Department of Pediatric Neurology
- Amrita Institute of Medical Sciences (AIMS)
- Kochi, Kerala, India
- Ch 17: Neonatal Seizures
- Suresh Ram
- Senior Resident
- Department of Pediatrics
- Institute of Medical Sciences
- Banaras Hindu University
- Varanasi, UP, India
- Ch 23: Acute Bronchiolitis
- M Ragavan
- Assistant Professor
- Department of Pediatric Surgery
- Narayana Medical College and Hospital
- Nellore, AP, India
- Ch 7: The Newborn with Respiratory Distress: Surgical Aspects
- Ch 32: Acute Abdomen
- Uma Raju
- Professor and Head
- Department of Pediatrics and Neonatology
- Command Hospital (Air Force)
- Bangalore, Karnataka, India
- Ch 13: Nosocomial Infections in the NICU
- Suresh Ram
- Senior Resident
- Department of Pediatrics
- Institute of Medical Sciences
- Banaras Hindu University,
- Varanasi, UP, India
- Ch 23: Acute Bronchiolitis
- R Renitha
- Senior Resident
- Department of Pediatrics
- Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)
- Puducherry, India
- Ch 9: Surfactant Therapy
- Anupam Sachdeva
- In-charge
- Pediatric Hematology, Oncology and Bone Marrow Transplantation Unit
- Sir Ganga Ram Hospital
- New Delhi, India
- Ch 28: Severe Anemia
- Satish Sabharwal
- Fellow in Pediatric Neurology
- Institute of Child Health
- Bristol, United Kingdom
- Ch 30: Acute Bacterial Meningitis
- Harsh Sharma
- Senior Registrar in Pediatrics
- Indira Gandhi Memorial Hospital Maldives
- Ch 8: Respiratory Distress Syndrome
- Ch 15: Neonatal Shock
- RK Sharma
- Lecturer in Neonatology
- University School of Medicine
- Philadelphia, United States
- Ch 11: Neonatal Meningitis
- R Rathi Sharmila
- Assistant Professor
- Department of Pediatrics
- Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)
- Puducherry, India
- Ch 24: Pneumonia
- Swati Singhal
- Lecturer
- Department of Pediatrics
- University College of Medical
- Sciences and Guru Teg Bahadur Hospital
- Delhi, India
- Ch 22: Status Epilepticus
- Utpal Kant Singh
- Professor and Head
- Department of Pediatrics
- Nalanda Medical College
- Patna, Bihar, India
- Ch 23: Acute Bronchiolitis
- Ch 29: Comatose Child
- Daljit Singh
- Senior Advisor (Pediatrics and Neonatology)
- Department of Pediatrics
- Command Hospital (SC)
- Pune, Maharashtra, India
- Ch 16: Neonatal Hypoglycemia
- Ch 18: Neonatal Jaundice
- Vishal Sondhi
- Pediatrician
- Military Hospital
- Saugor, MP, India
- Ch 14: Bleeding Disorders in the Neonate
- Ch 16: Neonatal Hypoglycemia
- Ch 18: Neonatal Jaundice
- Suprabha Patnaik Sondhi
- Pediatrician,
- Military Hospital
- Saugor, MP, India
- Ch 14: Bleeding Disorders in the Neonate
- Ch 18: Neonatal Jaundice
- WE Smith
- Associate Professor of Neonatology
- University School of Medicine
- Philadelphia, United States
- Ch 11: Neonatal Meningitis
- Nishant Verma
- Senior resident
- Department of Pediatrics
- Institute of Medical Sciences
- Banaras Hindu University (BHU)
- Varanasi, UP, India
- Ch 29: Comatose Child
- Sanjay Wazir
- Senior Consultant in Neonatology
- The Cradle (Apollo Hospital Initiative)
- Gurgaon, Haryana, India
- Ch 20: Analgesia and Sedation in Newborn
- SP Yadav
- Pediatric Hematology, Oncology and Bone Marrow Transplantation Unit
- Sir Ganga Ram Hospital
- New Delhi, India
- Ch 28: Severe Anemia
Since 1997, which marked the inception of the special volumes of the noted international series, Recent Advances in Pediatrics, first launched in 1991 and now concurrently in the 19th annual volume, we have come a long way. Among many special volumes, we brought out volumes on “Emergency Pediatrics”, “Neonatal Emergencies” and “Critical Care Pediatrics” which were warmly hailed by the fraternity both within India and abroad. The rapid advances in the field have prompted us to bring out yet another volume in the form of the present work, RAP Special Vol 21: Neonatal and Pediatric Intensive Care.
With the release of the 21st Special Volume (RAP Special Vol 21: Neonatal and Pediatric Intensive Care), and simultaneously, the 19th Annual Volume (RAP-19: Hot Topics), the noted international series, Recent Advances in Pediatrics, completes its two decades of uninterrupted publication. At this proud moment, we take the opportunity to salute all those who contributed to the success of this academic venture, directly and indirectly.
The 21st RAP Special Volume aims at covering topical issues in neonatal and pediatric intensive care. The 32 state-of-the-art chapters contributed by as many as 57 experts drawn from India and abroad attempt to review the depth and breadth of knowledge in the field of contemporary neonatal and pediatric intensive care with special reference to its applicability in the Indian subcontinent.
Each and every chapter is remarkable by its excellence, providing a stimulating and, not infrequently, even provocative, matured and informed update. Understandably, such an approach is befitting when the goal is not only to inform but also to motivate discussion, interaction, research and innovation.
In keeping with the professed policy of the series, multidisciplinary approach with an eye on future, continues to occupy pride of place in this volume too.
We are thankful to our distinguished contributors for providing excellent state-of-the-art chapters in various aspects of adolescence. They were also gracious enough to repose confidence in our editorship. Without their understanding and cooperation, this volume would not have seen the light of the day.
Hats off to the Advisory Editorial Board for providing inputs and advice in various editorial matters.
The help from our peer reviewers for critically reviewing the contributions is thankfully acknowledged. Their expert inputs indeed went a long way towards assessment, improvement, and eventually, excellence of the contents of this volume.
Grateful acknowledgements are hereby made to the Management and Administration of the Narayana Medical College and Hospitals, especially Dr P Narayana, Chairman, Dr C L Venkatarao, Adviser, Dr B A Ramakrishna, Principal and Dr P Narasimha Rao, Medical Superintendent and Dr S Vijay Kumar, Coordinator, for the moral support and motivation towards successful completion of this project.
Last, but by no means, the least, our daughter, Dr Novy, and son, Er Manu, voluntarily provided all sorts of assistance in taking this important project to its logical conclusion.
Finally, we wish to record our indebtedness to Jaypee Brothers Medical Publishers (P) Ltd and their dedicated staff for the skillful production qualities of the book.
Suraj Gupte
Academic Editor
Shamma-Bakshi Gupte
Executive Editor