Volume 1
Volume 2
Editor-in-Chief Vincent A Thamburaj
Senior Consultant Neurosurgeon Apollo Specialty Hospitals
Chennai, Tamil Nadu, India
Foreword Robin Sengupta
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This book has been published in good faith that the contents provided by the editor contained herein are original, and is intended for educational purposes only. While every effort is made to ensure accuracy of information, the publisher and the editor specifically disclaim any damage, liability, or loss incurred, directly or indirectly, from the use or application of any of the contents of this work. If not specifically stated, all figures and tables are courtesy of the editor. Where appropriate, the readers should consult with a specialist or contact the manufacturer of the drug or device.
Textbook of Contemporary Neurosurgery (Volume 1)
First Edition: 2012
9789350252390
Printed at
5Dedicated to
All my patients and their families
7Contributors
- Aashit K Shah
- Department of Neurology
- Wayne State University
- Detroit, MI, USA
- Abdul Ghafur
- Department of Infectious Diseases
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Abhijit K Hazra
- Department of Neurosurgery
- Government Medical College
- Nagpur, Maharashtra, India
- Amit K Thotakura
- Department of Neurosurgery
- NRI Academy of Medical Sciences
- Chinakakani, Andhra Pradesh, India
- Andrew M Lozen
- Department of Neurosurgery
- Wayne State University
- Detroit, MI, USA
- Anil P Karapurkar
- Department of Interventional Neurosurgery
- Sir Hurkisondas Nurrotumdas Hospital
- Mumbai, Maharashtra, India
- Anil Pande
- Achanta Lakshmipathi
- Neurosurgical Center
- VHS Hospitals
- Chennai, Tamil Nadu, India
- Anil Sangli
- Department of Neurosurgery
- Columbia Asia Hospital
- Mysore, Karnataka, India
- Annapurneswari Subramanyan
- Department of Pathology
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Anne Guyot
- Medical Director
- Neural Watch
- Ann Arbor, MI, USA
- Arul Kanagarajan
- Department of Neurosurgery
- Fortis Malar Hospital
- Chennai, Tamil Nadu, India
- Ashok Parameswaran
- Department of Pathology
- Apollo Hospitals
- Chennai, Tamil Nadu, India
- Avula Chakravarthi
- Department of Neurosurgery
- Bharathirajaa Hospital
- Chennai, Tamil Nadu, India
- Balaganapathy K Thiruvillamalai
- Department of Neurosurgery
- HJ Doshi Hospital and Research
- Rajkot, Gujarat, India
- Balaji Venugopal
- Department of Vascular Surgery
- Apollo Hospitals
- Chennai, Tamil Nadu, India
- Balamurugan Mangaleswaran
- Department of Neurosurgery
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Bapuji Cherukuri
- Department of Neuroanesthesia
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Bibhas Kar
- Department of Medical Genetics
- Apollo Hospitals
- Chennai, Tamil Nadu, India
- Chandrasekar Kalavakonda
- Department of Neurosurgery
- First Med Apollo Hospital
- Chennai, Tamil Nadu, India
- Chidambaram Balasubramaniam
- Department of Neurosurgery
- Childs Trust Hospital
- Chennai, Tamil Nadu, India
- Chidambaranathan Natesan
- Department of Radiology
- Apollo Hospitals
- Chennai, Tamil Nadu, India
- Deepak Arjundas
- Department of Neurology
- Apollo Hospitals
- Chennai, Tamil Nadu, India
- Dharmarajan N Seeniappa
- Department of Neurosurgery
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Fadi Delly
- Department of Neurosurgery
- Wayne State University
- Detroit, MI, USA
- Feda A Makkiyah
- Department of Neurosurgery
- Hasan Sadikin Hospital
- Jl. Pasir Kaliki No. 38
- Bandung, Indonesia – 40254
- Ganapathy Krishnan
- Department of Neurosurgery
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Ganapathy Krishnan
- Department of Plastic Surgery
- Apollo Hospitals
- Chennai, Tamil Nadu, India
- Ganesh Krishnamurthy
- Department of Neurosurgery
- Sri Ramachandra University
- Chennai, Tamil Nadu, India
- Geoffrey R Barger
- Department of Neurology
- Wayne State University
- Detroit, MI, USA
- Gerard Plans
- Department of Neurosurgery
- Calle Feixa Llarga s/n 08907
- L´Hospitalet de Llobregat
- Barcelona, Spain
- Hariprakash Chakaravarthy
- Department of Neurosurgery
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Hirotoshi Sano
- Department of Neurosurgery
- Fujita Health University
- 1–98 Dengakugakubo Kutsukake-cho
- Toyoake, Aichi, Japan
- Junichi Mizuno
- Center for Spine and
- Spinal Cord Disorders
- Southern Tohoku General Hospital
- Iwanuma, Miyagi, Japan
- Kalyanaraman Subramanian
- Department of Neurosurgery
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Kanthamani Polisetty
- Department of Ophthalmology
- Krishna Eye and ENT Hospital
- Chennai, Tamil Nadu, India
- Kazadi KN Kalangu
- Department of Neurosurgery
- University of Zimbabwe
- Harare, Zimbabwe
- Ketan R Bulsara
- Department of Neurosurgery
- Yale University
- Connecticut, USA
- Krishna Sharma
- Department of Neurosurgery
- B&B Hospital
- Kathmandu, Nepal
- Krishnaprasad Moodambikana
- Department of Neurosurgery
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Krzysztof Gil
- Department of Neurosurgery
- Medical University of Lublin
- Lublin, Poland
- Kundhala Ravi
- Department of Clinical Nutrition
- Sri Ramachandra University
- Chennai, Tamil Nadu, India
- Lakshman Vaidhyanathan
- Department of Hematology
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Lakshmi Sarma
- Department of Microbiology
- VHS Hospitals
- Chennai, Tamil Nadu, India
- Lakshmi Varadharajulu
- Department of Intensive Care
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Mahadev Potharaju
- Department of Radiation Oncology
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Mahmood Hassan
- Department of Neurosurgery
- Royal Commission Hospital
- Jubail, Kingdom of Saudi Arabia
- Mahmoud Rayes
- Department of Neurosurgery
- Wayne State University
- Detroit, MI, USA
- Manas Panigrahi
- Department of Neurosurgery
- Krishna Institute of Medical Sciences
- Secunderabad, Andhra Pradesh, India
- Manoj K Tewari
- Department of Neurosurgery
- Postgraduate Institute of Medical Education and Research
- Chandigarh, India
- Marina Rassou
- Department of Neurorehabilitation
- Apollo Hospitals
- Chennai, Tamil Nadu, India
- Mark Hoeprich
- Department of Neurosurgery
- Wayne State University
- Detroit, MI, USA
- Michael Brzozowski
- Department of Neurosurgery
- Medical University of Lublin
- Lublin, Poland
- Mohan R Sharma
- Department of Neurosurgery
- Tribhuvan University
- Kathmandu, Nepal
- Mohan Sampath Kumar
- Department of Neurosurgery
- SRM Medical College
- Chennai, Tamil Nadu, India
- Mohit Shidore
- Department of Neurosurgery
- Sparsh Hospital, Shahid Nagar
- Bhubaneswar, Odisha, India
- Monika Mittal
- Department of Neurosurgery
- Wayne State University
- Detroit, MI, USA
- Murali S Mohan
- Department of Neurosurgery
- MS Ramaiah Medical College
- Bengaluru, Karnataka, India
- Murugan Logamuthukrishnan
- Department of Neurosurgery
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Narayanan Raghavachari
- Department of Neurosurgery
- Lifeline Hospitals
- Chennai, Tamil Nadu, India
- Natarajan Perumal
- Department of Neurosurgery
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Nigel P Symss
- Achanta Lakshmipathi
- Neurosurgical Center
- VHS Hospitals
- Chennai, Tamil Nadu, India
- Nirmala Arulraj
- Department of Radiology
- First Med Apollo Hospital
- Chennai, Tamil Nadu, India
- Nishant K Aditya
- Department of Interventional Neurosurgery
- Sir Hurkisondas Nurrotumdas Hospital
- Mumbai, Maharashtra, India
- Panneer Adhinarayanan
- Department of Neurology
- Apollo Hospitals
- Chennai, Tamil Nadu, India
- Prakash Modha
- Department of Neurosurgery
- PDU Medical College
- Rajkot, Gujarat, India
- Prativa Misra
- Department of Ophthalmology
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Prithika Chary
- Department of Neurology
- Global Hospitals
- Chennai, Tamil Nadu, India
- Purav Patel
- Department of Neurosurgery
- Wockhardt Hospitals
- Bhavnagar, Gujarat, India
- Radoslaw Rola
- Department of Neurosurgery
- Medical University of Lublin
- Lublin, Poland
- Rammohan M Naidu
- Department of Neuroanesthesia
- Apollo Hospitals
- Chennai, Tamil Nadu, India
- Ramnarayanan Ramachandran
- Department of Neurosurgery
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Ranjan K Mohapatra
- Department of Medical Oncology
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Ravi Bhatia
- Department of Neurosurgery
- Indraprastha Apollo Hospitals
- New Delhi, India
- Ravi Ramamurthi
- Achanta Lakshmipathi
- Neurosurgical Center
- VHS Hospitals
- Chennai, Tamil Nadu, India
- Ravikanth Balaji
- Department of Radiology
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Ravindra Kamble
- Department of Interventional Radiology
- Sri Ramachandra University Hospital
- Chennai, Tamil Nadu, India
- Ravishankar L Subramaniam
- Department of Urology
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Ravishankar V Emani
- Department of Neurosurgery
- Sai Vani Hospital
- Hyderabad, Andhra Pradesh, India
- Rayappa Chinnasamy
- Department of ENT Surgery
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Reginald John
- Department of Neurosurgery
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Ritesh K Bhoot
- Department of Neurosurgery
- Vivekananda Medical Mission
- Bhubaneswar, Odisha, India
- Sajan K Hegde
- Department of Spinal Surgery
- Apollo Hospitals
- Chennai, Tamil Nadu, India
- Samit S Mehta
- Department of Neurosurgery
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Sammandam Karunagaran
- Department of Spinal Surgery
- Apollo Hospitals
- Chennai, Tamil Nadu, India
- Sandeep Mittal
- Department of Neurosurgery
- Wayne State University
- Detroit, MI, USA
- Santhosh Joseph
- Department of Interventional Radiology
- Sri Ramachandra University Hospital
- Chennai, Tamil Nadu, India
- Saroja Srinivasan
- Department of Internal Medicine
- VHS Hospital
- Chennai, Tamil Nadu, India
- Selvakumar Kumaravelu
- Department of Neurosurgery
- Sri Ramachandra University
- Chennai, Tamil Nadu, India
- Siddhartha Ghosh
- Department of Neurosurgery
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Sivakumar M Rajappa
- Department of Neurology
- Bharathirajaa Hospital
- Chennai, Tamil Nadu, India
- Spyros Sgouros
- Department of Neurosurgery
- “Attikon” University Hospital
- Athens, Greece
- Sridhar Krishnamurthy
- Department of Plastic Surgery
- Apollo Hospitals
- Chennai, Tamil Nadu, India
- Sridharan Ramaratnam
- Department of Neurology
- Apollo Hospitals
- Chennai, Tamil Nadu, India
- Sudheer K Tyagi
- Department of Neurosurgery
- Indraprastha Apollo Hospitals
- New Delhi, India
- Sundar Venkataraman
- Department of Neurosurgery
- Madras Medical College
- Chennai, Tamil Nadu, India
- Sunil Perera
- Department of Neurosurgery
- National Hospital
- Colombo, Sri Lanka
- Suresh Bapu R Kandallu
- Department of Neurosurgery
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Suresh N Mathuriya
- Department of Neurosurgery
- Postgraduate Institute of Medical
- Education and Research
- Chandigarh, India
- Tanuj Nayyar
- Department of Neurosurgery
- Apollo BGS Hospital
- Mysore, Karnataka, India
- Tetsuo Kanno
- Department of Neurosurgery
- Fujita Health University
- 1–98 Dengakugakubo Kutsukake-cho
- Toyoake, Aichi, Japan
- Thomas L Beaumont
- Department of Neurosurgery
- Wayne State University
- Detroit, MI, USA
- Vasudevan M Chakravarthi
- Achanta Lakshmipathi
- Neurosurgical Center
- VHS Hospitals
- Chennai, Tamil Nadu, India
- Venkatavaradan Raghavan
- Department of Ophthalmology
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- Vincent A Thamburaj
- Department of Neurosurgery
- Apollo Specialty Hospitals
- Chennai, Tamil Nadu, India
- William J Kupsky
- Department of Pathology
- Wayne State University
- Detroit, MI, USA
- Yogaraj Subramanian
- Department of Neurology
- Apollo Hospitals
- Chennai, Tamil Nadu, India
- Yoko Kato
- Department of Neurosurgery
- Fujita Health University
- 1–98 Dengakugakubo Kutsukake-cho
- Toyoake, Aichi, Japan
‘Teaching is the highest form of understanding.’ — Aristotle (384–322 BC), Greek Philosopher
Today, Neurosurgeons have to know much more to keep up with the latest method of diagnosis and treatment. To fulfill their needs a contemporary textbook is therefore an absolute necessity and long overdue. The first Textbook of Neurosurgery by pioneer giants in Indian Neurosurgery Dr B Ramamurthi and Dr PN Tandon was published in 1980. More than 30 years later, Dr Vincent A Thamburaj, whom I know from his years in England, has taken the audacious and arduous task to write another textbook on Neurosurgery.
This book covers the entire field of general neurosurgery, including neurorehabilitation. The chapters on Evidence-based Medicine for Neurosurgeons, Ethics in Neurosurgery, Genetics in Neurosurgery, Familial Tumor Syndromes of the Central Nervous System, Biomechanics of Spinal Stabilization, Stem Cells in Neurology, and Neurological Physiotherapy are some of the chapters not usually found in general neurosurgical textbooks. The discussion on developmental disorders is very illustrative. The section on ‘Infections in Neurosurgery’ will be informative to the Western world. The wide spectrum of brain tumors has been discussed most comprehensively. The recent neurosurgical interest in spine surgery is well reflected in section ‘Spine and Spinal Cord Disorders’.
As Vincent mentions in his preface, the book is primarily intended for the postgraduate students, neurosurgeons who have to look after all kinds of neurosurgical problems in the community and the medical practitioners who need some guidance about neurosurgical problems in their own specialties. However, I find that the quality of information and presentations in the book can even help the neurosurgical experts in the areas of their own interest. Dr B Ramamurthi would have been delighted to see this book coming from his own student, Dr Vincent A Thamburaj and from his beloved city, Chennai, from where he radiated Neurosurgical gospel throughout India and became the Ambassador of Indian Neurosurgery to the rest of the world. Most of the premiere institutions, which are well known for education and research, are losing their talents to the corporate sector. It is therefore surprising that Vincent could assemble so many Indian Neurosurgeons to contribute to this book. I notice that apart from few Japanese and Western experts, the authors are all Indian. What a testimony to the persuasive power of the editors! I congratulate Vincent and his team for creating another milestone in Indian Neurosurgery. I am sure that this timely, comprehensive and up-to-date textbook will be well received by Neurosurgeons, the world over.
Newcastle upon Tyne, UK
Robin Sengupta
Visiting Professor, Dr MGR Medical University, Chennai, Tamil Nadu, India
Fellow, National Academy of Science, India
Emeritus Fellow, Durham University, UK
Consultant Neurosurgeon, Newcastle upon NHS Trust, UK
Chairman, Institute of Neurosciences, Kolkata, West Bengal, India
Chairman, National Neurosciences Centre, Kolkata, West Bengal, India
13Preface
‘There are moments in a man's life when purpose comes to him suddenly.’
— Wilder Graves Penfield (1891–1976), Canadian Neurosurgeon
The genesis of this textbook can be traced back to my online tome ‘Neurosurgery on the web…’ It was personally very gratifying to see the neurosurgery community adopt and benefit from this online manual. Generous feedback from the community encouraged me to further develop this work and then to mold the contents into textbook form. Over the course of multiple iterations of additions, deletions and edits, the content was eventually shaped into the final product that you now see.
This textbook is primarily directed at Neurosurgical Trainees. Young Neurosurgeons and those in related disciplines will also appreciate and benefit from the material in the book. While the textbook covers topics that every general Neurosurgeon should be knowledgeable at, it is beyond the scope of this work to address the specific needs of subspecialists.
There are 121 chapters organized into 14 sections in two volumes. Each chapter attempts to draw together all current relevant information and integrates theory and practice in contemporary neurosurgery for a comprehensive learning experience. The concise and practical style is deliberately chosen to make this textbook easy to consume. Each chapter begins with an introduction to the topic and ends with key practice points for a quick review of the topic. All chapters follow the same format so that there are no inconsistencies in style or content. Every effort has been made to avoid redundancy, which is often inevitable in a textbook with multiple authors.
During my FRCS days, I really enjoyed reading Walter and Israel's General Pathology. They set the bar for me in terms of what a medical textbook ought to be. My goal was to attempt to write a book that is as expansive and as approachable as that seminal work. It is my fervent hope that you, the reader, find this book informative, interesting and easy to read.
I wish to thank all the authors who have contributed so generously of their experience and their time and the staff of Jaypee Brothers Medical Publishers (P) Ltd, New Delhi, India who were most helpful in getting the book published.
I would especially like to thank Narayanan Raghavachari for his help with proofreading, Ravikanth Balaji for his help with figures, and Anil Sangli and Samit S Mehta who shared in the conception and planning of this textbook.
Vincent A Thamburaj