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Recent Advances in Surgery 34
Colin D Johnson, Irving Taylor
SECTION ONE: SURGERY IN GENERAL
CHAPTER ONE:
Update on the Management of the Surgical Patient with Diabetes
INTRODUCTION
PREOPERATIVE EVALUATION
PREOPERATIVE LABORATORY INVESTIGATIONS
EFFECT OF SURGERY ON GLYCAEMIC CONTROL
GLYCAEMIC TARGETS
EARLY PERIOPERATIVE PHASE
Type 2 Diabetes Treated with Diet Alone
Type 2 Diabetes Treated with Oral Hypoglycaemic Agents
Type 1 or Insulin Treated Type 2 Diabetes
TIMING OF PROCEDURE
Minor and Short Morning Operations
Long and Complex Procedures for Type 1 or Insulin Treated Type 2 Diabetes
Glucose Insulin Potassium Infusion
Separate Insulin and Glucose Intravenous Solutions
LATE POSTOPERATIVE PHASE
SUBCUTANEOUS BOLUS INSULIN DOSES
SPECIAL CONSIDERATIONS
Glucocorticoid Therapy
Hyperalimentation
Preoperative Carbohydrate Loading
Patients Undergoing Coronary Artery Bypass Graft Surgery (CABG)
Intensive Insulin Therapy in Critically Ill Surgical Patients
CONCLUSIONS
CHAPTER TWO:
How Guidelines Influence Modern Surgical Practise
INTRODUCTION
STATUTORY GUIDELINES (SUBJECT TO LAW)
Guidance Produced by the General Medical Council (GMC)
ADVISORY GUIDELINES
ASSESSMENT OF GUIDELINES
GRADE SYSTEM CLASSIFICATION FOR QUALITY OF EVIDENCE14
Quality of Evidence and Definitions
GRADE SYSTEM CLASSIFICATION FOR STRENGTH OF RECOMMENDATIONS14
CONCLUSION
CHAPTER THREE:
Patient Consent for Surgical Treatment
INTRODUCTION
IS MORE THAN ONE CONSENT EVER REQUIRED?
WHAT LEVEL OF OPERATIVE RISK SHOULD BE DISCLOSED?
CAN CONSENT BE IMPLIED?
IS THERE A DUTY OF SURGICAL CANDOR?
SECTION TWO: UPPER GASTROINTESTINAL TRACT/HEPATO-PANCREATIC-BILIARY TRACT
CHAPTER FOUR:
Gastric Outlet Obstruction in Adults
INTRODUCTION
Metabolic Disturbance
MANAGEMENT OF GOO
GOO Caused By Malignancy
Antecolic or Retrocolic Anastomosis
Open, Laparoscopic or Laparoscopic-Assisted?
Prevention of GOO
Duodenal Stents
Benign Peptic Stricture
Chronic Pancreatitis
CONCLUSIONS
CHAPTER FIVE:
Surgery for Advanced Gallbladder Cancer
INTRODUCTION
SURGICAL PATHOLOGY
ASSESSMENT
Upper GI/HPB
SURGICAL MANAGEMENT IN ADVANCED CANCER (AJCC STAGE II, III AND IV)
T2 Tumours with Lymph Node Involvement
T3 Tumours
T4 Tumours
Consideration of Extra Hepatic Bile Duct Excision
Management of GBC: Post Cholecystectomy
PALLIATIVE SURGERY IN ADVANCED GALLBLADDER CANCER
Palliation of Jaundice
Surgical Palliation for Bowel Obstruction
CHEMORADIATION THERAPY
PROGNOSIS
SUMMARY
CHAPTER SIX:
Laparoscopic or Open Liver Resection?
EVOLUTION OF LIVER SURGERY
LAPAROSCOPIC LIVER RESECTION: THE NEXT PARADIGM
INDICATIONS AND CASE SELECTION
EVALUATION OF LAPAROSCOPIC LIVER RESECTION: IS THE EVIDENCE THERE?
SHORT-TERM OUTCOMES
LAPAROSCOPIC LIVER RESECTION FOR MALIGNANT DISEASE
Colorectal Liver Metastases
Hepatocellular Carcinoma
CONCLUSION
CHAPTER SEVEN:
Volume and Outcome in Upper Gastrointestinal Malignancy
INTRODUCTION
HOSPITAL VOLUME AND UPPER GI CANCER SURGERY
SPECIFIC AREAS WHERE HOSPITAL VOLUME INFLUENCES OUTCOME
Staging in Upper GI Malignancy
Quality of Surgery
Postoperative Complications
Postoperative Mortality
Length of Stay
Long-Term Survival
Economic Cost
INDIVIDUAL SURGEON VOLUME AND UPPER GI CANCER SURGERY
SPECIFIC AREAS WHERE SURGEON VOLUME INFLUENCES OUTCOME
Quality of Surgery
Postoperative Mortality
Postoperative Complications
Long-Term Survival
Economic Cost
FACTORS UNDERLYING THE VOLUME-OUTCOME RELATIONSHIP
Preoperative Factors
Intraoperative Factors
Postoperative Factors
IMPORTANCE OF STUDY DESIGN
Definition of Volume
Data Source and Analysis
Adjustment for Case-mix
EFFECT OF THE VOLUME-OUTCOME RELATIONSHIP ON SERVICE PROVISION
Centralisation of Surgical Services
Quality Improvement Strategies
Recommended Ideal Volume Thresholds
CONCLUSIONS
SECTION THREE: LOWER GASTROINTESTINAL TRACT
CHAPTER EIGHT:
Modern Management of an Intestinal Fistula
INTRODUCTION
AETIOLOGY
RISK FACTORS AND THE PREVENTION OF FISTULATION
Preoperative Risk Factors (correcting what is reversible)
Perioperative Risk Factors, Surgical Decision Making and the Judicious Use of Stomas
Postoperative Risk Factors: Avoidance of Repeat Laparotomies
POORLY MANAGED SURGICAL CATASTROPHE
Clinical Course of a Poorly Managed Intestinal Fistula
When Repeat Laparotomy is Mandatory
Principles to be Followed in Complicated Cases
OCCURRENCE OF FISTULA
Sepsis
Wound Care
Nutrition
Physiology
Fluid Balanc—Working out the Basal Output
Decreasing Output
Step 1: Appropriate Isotonics and Fluid Restriction
Step 2: Proton Pump Inhibition
Step 3: Loperamide and Codeine Phosphate
Step 4: Octreotide
High Output Despite Intervention
Low Output
Intermediate Group
Monitoring Fluid and Electrolyte Status
Nutrition
ANATOMY—THE CHANCE OF SPONTANEOUS CLOSURE AND APPROPRIATE INVESTIGATIONS
Timing of Surgery—More Art than Science
STRATEGY OF SURGERY
Dealing with the Fistula
Reconstructing the Abdominal Wall
Use of Prosthetic Mesh
Use of Biological Mesh
FOLLOW-UP FOLLOWING ENTEROCUTANEOUS FISTULA REPAIR
CONCLUSION
CHAPTER NINE:
Rectal and Pelvic Prolapse
INTRODUCTION
FULL-THICKNESS RECTAL PROLAPSE
Choice of Surgical Procedure
Abdominal Procedures
Posterior Rectopexy
Resectional Rectopexy
Ventral Rectopexy
Perineal Procedures
Delorme's Procedure
Altemeier's Rectosigmoidectomy
Stapled Transanal Rectal Resection (STARR)
Internal Rectal Prolapse
Choice of Surgical Procedure
Internal Delorme's Procedure
Laparoscopic Sacrocolporectopexy (Ventral Rectopexy)
Stapled Transanal Rectal Resection (STARR) and Transtar
Express Procedure
RECTAL AND OTHER PELVIC ORGAN PROLAPSE
CHAPTER TEN:
Modern Surgical Management of Haemorrhoids
INTRODUCTION
PATHOPHYSIOLOGY
PRESENTATION AND DIAGNOSIS
TREATMENT
Conservative Methods
Over the Counter Preparations
Out-Patient Clinic
Submucosal Sclerosant Injection
Rubber Band Ligation
Surgical Treatments
Haemorrhoidal Artery Ligation
Stapled Haemorrhoidopexy
Surgical Haemorrhoidectomy
Cochrane Collaborative Comparison of Treatments
Our Own Practice
NEW TECHNIQUES
SECTION FOUR: BREAST
CHAPTER ELEVEN:
Radiotherapy for the Breast Surgeon
INTRODUCTION
EXTERNAL BEAM RADIOTHERAPY
Whole Breast Radiotherapy
Hypofractionated Radiotherapy Regimens
Post-mastectomy Radiotherapy
Intensity Modulated Radiotherapy (IMRT)
Partial Breast Radiotherapy
Intraoperative Radiotherapy
Brachytherapy
CONCLUSION
CHAPTER TWELVE:
An Update on the Management of the Axilla in Breast Cancer
INTRODUCTION
DIAGNOSING DISEASE OF THE AXILLA
SENTINEL LYMPH NODE BIOPSY (SLNB)
Technique
Removal of SLNs
Prognostic Value of SLNB
Negative SLNB
Positive SLNB
RADIOLOGICAL STAGING OF AXILLA
Clinically Palpable ALNs
THERAPEUTIC MANAGEMENT OF THE AXILLA
Axillary Lymph Node Dissection (ALND)
Axillary Node Sampling (ANS)
Management of the Axilla in DCIS
RADIOTHERAPY AS TREATMENT OF AXILLARY DISEASE
CONCLUSION
SECTION FIVE: VASCULAR SURGERY
CHAPTER THIRTEEN:
Recent Advances in Endovascular Management of Aortic Aneurysms
INTRODUCTION
LEVEL ONE EVIDENCE FOR EVAR
EVAR I and II2 Trial Design
DREAM3 Trial Design
EVAR I4 Early Results
DREAM5 Early Results
EVAR 17 Midterm Results
EVAR Trial 28
Long-Term Results for EVAR 1 Trial9
Long-Term Results for EVAR 2 Trial10
Long-Term Results for DREAM Trial11
ANEURYSM SCREENING
EVAR FOR RUPTURED ANEURYSMS
EVAR FOR SMALL ANEURYSMS
BRANCHED/FENESTRATED EVAR
Fenestrated Endovascular Aneurysm Repair: World Wide Experience
Device Improvements
CONCLUSION
SECTION SIX: SURGICAL ONCOLOGY
CHAPTER FOURTEEN:
Management of Retroperitoneal Sarcoma
INTRODUCTION
DIAGNOSIS
Clinical Presentation
Pathology
INVESTIGATIONS
Imaging
Biopsy
Staging
MANAGEMENT
Surgery
Surgical Outcome
Radiation Therapy
Chemotherapy
Neoadjuvant Chemotherapy
Adjuvant Chemotherapy
Palliative Chemotherapy
Locally Recurrent Tumours
Unresectable and Metastatic Disease
PROGNOSTIC FACTORS
FUTURE DIRECTIONS
SECTION SEVEN: CLINICAL TRIALS
CHAPTER FIFTEEN:
Randomised Clinical Trials and Meta-analyses in Surgery 2010
INTRODUCTION
GENERAL
LAPAROSCOPIC SURGERY
UPPER GASTROINTESTINAL
Gastro-oesophageal Reflux Disease
Gastric Carcinoma
Gastric Outlet Obstruction
HEPATO-PANCREATIC AND BILIARY
Pancreatic Surgery
Biliary
COLORECTAL
Colorectal Cancer
Fissure in Ano
HERNIA
BREAST
INDEX
TOC
Index
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