Second Edition
Edited by Krishna M Goel MD DCH FRCP (Lond, Edin and Glas) Hon FRCPCH
Formerly Honorary Senior Lecturer of Child Health University of Glasgow and Consultant Paediatrician at the Royal Hospital for Sick Children
Yorkhill, Glasgow, Scotland, UK
Devendra K Gupta MS MCh FAMS (Hon) FCSS FRCS (Edin) FRCS (Glas) FAMS (Rom) DSc (Honoris Causa)
Vice Chancellor Chhatrapati Shahuji Maharaj Medical University
Lucknow, Uttar Pradesh, India
Foreword Professor Terence Stephenson
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Hutchison's Paediatrics
First Edition: 2009
Second Edition: 2012
9789350257715
Printed at
5Contributors
- Alastair Turner
- bsc med sci mbchb mrcpch
- Consultant Paediatric Intensive Care
- Honorary Senior Clinical Lecturer
- University of Glasgow
- Royal Hospital for Sick Children
- Glasgow, Scotland, UK
- Alison M Cairns
- msc bds mfds frcs (edin) m paed dent (rcpsg)
- Clinical Lecturer in Paediatric Dentistry
- University of Glasgow Dental Hospital and School, Glasgow, Scotland, UK
- Anne Margaret Devenny
- mbchb mrcp (uk) frcpch
- Paediatric Respiratory Consultant
- Royal Hospital for Sick Children
- Glasgow, Scotland, UK
- Beena Koshy
- mbbs md (paed) pdfdp
- Assistant Professor of Developmental
- Paediatrics, Christian Medical College
- Vellore, Tamil Nadu, India
- Benjamin Joseph
- ms orth mch orth
- Professor of Orthopaedics and Head of Paediatric Orthopaedic Service
- Kasturba Medical College
- Manipal 576104, Karnataka, India
- Christina Halsey
- bm bch ba (hons) mrcp mrcpath phd
- Honorary Consultant Paediatric
- Haematologist and Scottish Senior
- Clinical Fellow
- Department of Paediatric Haematology
- Royal Hospital for Sick Children
- Glasgow, Scotland, UK
- Chikkanayakanahali Manjunatha
- md (paed) dch dnb (paed) mrcp (uk) frcpch
- Consultant Neonatologist
- Wishaw General Hospital
- 50, Netherton Road
- Wishaw ML2 0DP
- Lanarkshire, Scotland, UK
- Craig Williams
- md frcp frcpath
- Consultant Microbiologist
- Royal Hospital for Sick Children
- Glasgow, Scotland, UK
- David James
- mbchb dip ed dch dpm frcpsych frcp (glas)
- Retired Child Psychiatrist formerly at Department of Child and Family
- Psychiatry
- Royal Hospital for Sick Children
- Glasgow, Scotland, UK
- Devendra K Gupta
- ms mch fams (hon) fcss frcs (edin) frcs (glas) fams (rom) dsc (honoris causa)
- Vice Chancellor
- Chhatrapati Shahuji Maharaj Medical University
- Lucknow, Uttar Pradesh, India
- Elizabeth A Chalmers
- mbchb md mrcp (uk) frcpath
- Consultant Paediatric Haematologist
- Royal Hospital for Sick Children
- Glasgow, Scotland, UK
- James Wallace
- bsc mr pharms frcpch (hon)
- Chief Pharmacist
- Yorkhill Hospitals
- Glasgow, Scotland, UK
- Jean Herbison
- mbchb mrcp frcpch dcch mfflm
- Consultant Paediatrician and Clinical
- Director for Child Protection Services
- Greater Glasgow and Clyde Health Board
- Child Protection Unit
- Royal Hospital for Sick Children
- Glasgow, Scotland, UK
- Judy Ann John
- md dipnb (pmr)
- Associate Professor
- Department of Physical Medicine and Rehabilitation
- Christian Medical College
- Vellore, Tamil Nadu, India
- Jugesh Chhatwal
- md dch
- Professor and Head of Paediatrics
- Christian Medical College
- Ludhiana, Punjab, India
- Khursheed F Moos
- mbbs (lond) bds (lond) frcs (edin) fds rcs (eng and edin) fds rcps (glasg) frcps (glasg) honorary fcps (pakistan) honorary obe
- Honorary Professor of Oral and Maxillofacial Surgery—Glasgow
- University, Consultant Oral and Maxillofacial Surgeon—West of Scotland
- Plastic and Maxillofacial Unit
- Canniesburn Hospital
- Glasgow Civilian Consultant to the Royal Navy
- Scotland, UK
- Kirsteen J Thompson
- msc frcs (edin)
- Consultant Ophthalmologist
- Inverclyde Royal Hospital
- Greenock, Scotland, UK
- Krishna M Goel
- md dch frcp (lond, edin & glas) hon frcpch
- Formerly Honorary Senior Lecturer of Child Health, University of Glasgow and Consultant Paediatrician
- Royal Hospital for Sick Children
- Glasgow, Scotland, UK
- Louis Low
- mbchb mrcp (uk) frcp (lond, edin & glas) frcpch
- Honorary Clinical Professor in Paediatrics
- Department of Paediatrics and Adolescent Medicine
- The University of Hong Kong
- Queen Mary Hospital
- Pokfulam, Hong Kong
- Lydia Edward Raj
- msot
- Reader (In-charge OT Education)
- Department of Physical Medicine and Rehabilitation
- Christian Medical College
- Vellore, Tamil Nadu, India
- Margo L Whiteford
- bsc frcp (glasgow)
- Consultant Clinical Geneticist
- Ferguson-Smith Centre for Clinical Genetics
- Yorkhill Hospital
- Glasgow, Scotland, UK
- Mary Mealyea
- mbchb diploma in dermatology
- Associate Specialist in Paediatric Dermatology
- Royal Hospital for Sick Children
- Glasgow, Scotland, UK
- Maya Mary Thomas
- mbbs dch md (paeds) dm (neuro)
- Associate Professor and Paediatric
- Neurologist, Department of Neurological Sciences, Christian Medical College
- Vellore, Tamil Nadu, India
- Michael Morton
- mphil ma mbchb frcpsych frcpch
- Consultant Child & Adolescent Psychiatrist
- In-patient & Liaison Child & Adolescent
- Psychiatry with Neuropsychiatry
- Department of Child & Family Psychiatry
- Royal Hospital for Sick Children
- Glasgow, Scotland, UK
- NV Doraiswamy
- ms frcs (edin & glas) fics fiss ffaem frcpch
- Consultant Surgeon (Retd)
- Royal Hospital for Sick Children
- Glasgow, Scotland, UK
- Paul Galea
- md dch frcp (glas) frcpch
- Consultant Paediatrician
- Royal Hospital for Sick Children
- Glasgow, Scotland, UK
- Peter Galloway
- bsc dch frcp (edin & glas) frcpath
- Consultant Medical Biochemist
- Royal Hospital for Sick Children,
- Glasgow, Scotland, UK
- Phyllis Kilbourn
- International Director
- Crisis Care Training International
- International Office, PO Box 517
- Fort Mill, South Carolina, USA
- Prabhakar D Moses
- mbbs md (paed) mrcp (uk) frcp (edin) fcams
- Professor and Head of Paediatrics Unit 111
- Christian Medical College
- Vellore, Tamil Nadu, India
- Rajeev Srivastava
- mbbs ms (orth) frcs (g) frc path
- Consultant Medical Biochemist
- Royal Hospital for Sick Children
- Glasgow, Scotland, UK
- Richard Welbury
- bds (hons) mbbs phd fdsrcs fdsrcps frcpch
- Professor of Paediatric Dentistry
- University of Glasgow Dental Hospital and School
- Glasgow, Scotland, UK
- Robert Carachi
- md phd frcs (glas & eng) febps
- Professor of Surgical Paediatrics
- University of Glasgow
- Royal Hospital for Sick Children
- Glasgow, Scotland, UK
- Rosemary Anne Hague
- md mrcp (uk) frcpch
- Consultant Paediatric ID/Immunology
- Yorkhill NHS Trust
- Royal Hospital for Sick Children
- Glasgow, Scotland, UK
- Rosemary Sabatino
- Trainer and Educator
- Crisis Care Training International
- International Office
- PO Box 517, Fort Mill
- South Carolina, USA
- Samuel E Ibhanesebhor
- fwacp fmcpaed frcpch frcp (glasg)
- Consultant Neonatologist
- Wishaw General Hospital
- 50, Netherton Road
- Wishaw ML2 0DP
- Lanarkshire, Scotland, UK
- Sandra J Butler
- bsc (hons) mbchb mrcpch frcr
- Consultant Paediatric Radiologist
- Royal Hospital for Sick Children
- Glasgow, Scotland, UK
- Sanjay V Maroo
- mbchb m-med frcr
- Consultant Paediatric Radiologist
- Royal Hospital for Sick Children
- Glasgow, Scotland, UK
- Sarada David
- ms do
- Professor and Head
- Department of Ophthalmology
- Christian Medical College
- Vellore, Tamil Nadu, India
- Shilpa Sharma
- ms mch dnb phd
- Associate Professor
- Paediatric Surgery
- 416 Administration Block
- PGIMER, Dr RML Hospital
- Baba Kharg Singh Marg
- Connaught Place
- New Delhi, India
- Syed Rehan Ali
- mb dch mrcp frcp
- Assistant Professor and Consultant in Neonatal Medicine
- Director of Neonatal Services
- Department of Paediatrics and Child Health
- Aga Khan University Hospital
- Karachi, Pakistan
- Tahmeed Ahmed
- mbbs phd
- Head, Nutrition Programme Scientist
- Clinical Sciences Division
- International Centre for Diarrhoeal
- Diseases Research, B
- Dhaka, Bangladesh
- Trevor Richens
- mbbs bsc (hons) mrcp (lond)
- Consultant Paediatric Cardiologist
- Royal Hospital for Sick Children
- Glasgow, Scotland, UK
- Zulfiqar Ahmed Bhutta
- mbbs frcp frcpch fcps phd
- The Husein Lalji Dewraj
- Professor and Chairman
- Department of Pediatrics and Child Health
- The Aga Khan University and Medical Center
- Karachi, Pakistan
The world moves at a frightening pace and sometimes I hear a view expressed that textbooks are a thing of the past. We should be able to get all the information we need from the Internet and what is more, it is argued, it is more likely to be up-to-date. I disagree. I think there is still a place for a well written, comprehensive textbook and I use the books on my shelves most days. The reader can have confidence in the contents if they are familiar with the authors and editors and this is an advantage that has to be set against the potential benefits of electronic information. Whilst the Internet is likely to be updated in real time, there is very little peer review or filtering of the information placed on it and the reader can rarely be sure of the provenance of the opinions expressed.
I am delighted that Krishna M Goel and Devendra K Gupta have produced the second edition of their marvellous textbook Hutchison's Paediatrics. This will be of great value to all those who use it, whether students, or those preparing for professional examinations, or simply (like myself) keeping up-to-date or finding the answers to difficult clinical problems in daily practice.
James Holmes Hutchison graduated at the University of Glasgow. He served in the Second World War rising to the rank of Lieutenant Colonel and was awarded an Order of the British Empire in 1945. He returned to the Hospital for Sick Children in Glasgow and subsequently became the Samson Gemmel Professor in Paediatrics. He was President of the Royal College of Physicians and Surgeons of Glasgow, then became President of the British Paediatric Association and then served as Dean of the Faculty of Medicine in Glasgow. Following his time in Glasgow, he was appointed Professor of Paediatrics at the University of Hong Kong.
I hope you enjoy reading Hutchison's Paediatrics in this new edition as much as I have.
Professor Terence Stephenson
dm frcp (lon) frcpch
President
Royal College of Paediatrics and Child Health
University of Nottingham
Nottingham, UK
9Preface to the Second Edition
The patterns of childhood disease throughout the world are changing with advancing knowledge, altering standards of living, lifestyle and rising levels of medical care. The origins of physical and mental health and disease lie predominantly in the early development of the child. Most of the abnormalities affecting the health and behaviour of children are determined prenatally or in the first few years of life by genetic and environmental factors. The authors have summarised the current knowledge of causation and have indicated where health education and prevention might reduce the burden of childhood ill health.
The more diverse authorship of chapters in this second edition reflects the growing dependence upon cooperative interests of colleagues in paediatrics. In clinical practice, such collaborative work can only be accomplished within a large hospital or a unit devoted to children. Both editors have been fortunate to work in such an environment and believe that the highest standards of paediatric practice can only be attained in such circumstances. In this, the second edition, we welcome ten new contributors. In this book we seek to provide practical advice about the diagnosis, investigation and management of the full spectrum of childhood disorders, both medical and surgical. We have tried to indicate, and where appropriate to describe, techniques and laboratory investigations which are necessary for advanced diagnosis and up-to-date therapy. Attention is directed to the special problems which arise in the developing countries. The need for such a text has been confirmed by the success of the first edition, published in 2009. As is often the case, space limitation demands some selectivity of content. It is intended in a true apprenticeship fashion of teaching to provide a manageable, readable and practical account of clinical paediatrics for medical undergraduates, for postgraduates specialising in paediatrics and for general practitioners whose daily work is concerned with care of children in health and sickness. Knowledge within the field of paediatrics continues to increase exponentially. Accordingly, many chapters in this edition were completely revised, updated and extended with an additional four chapters. Many figures illustrating salient concepts summarising clinical findings and treatment results have been added.
We are especially grateful to the parents and to the many children and their families who contributed to our knowledge and understanding of paediatrics and willingly gave permission to reproduce photographs of their children. A book such as this cannot be written without reproducing material reported in the medical literature. We acknowledge here, with gratitude, the permission granted free of charge by individual publishers to reproduce material for which they hold the copyright.
We particularly wish to thank the Hutchison family for allowing us to use the name of the late Professor James Holmes Hutchison, the author of ‘Practical Paediatric Problems’ to enable us to title this book Hutchison's Paediatrics. Even today, Hutchison's name is highly respected in the paediatric world.
Finally, we are grateful to the various contributors to this second edition for their cooperation in its production.
Krishna M Goel
Devendra K Gupta
11Preface to the First Edition
The patterns of childhood disease throughout the world are changing with advancing knowledge, altering standards of living, lifestyle and rising levels of medical care. The origins of physical and mental health and disease lie predominantly in the early development of the child. Most of the abnormalities affecting the health and behaviour of children are determined prenatally or in the first few years of life by genetic and environmental factors. The range of contributors indicates that they are all experts in their particular fields. The authors have summarised the current knowledge of causation and have indicated where health education and prevention might reduce the burden of childhood ill health. We seek in this book to provide practical advice about the diagnosis, investigation and management of the full spectrum of childhood disorders, both medical and surgical. We have tried to indicate and where appropriate to describe, techniques and laboratory investigations which are necessary for advanced diagnosis and up-to-date therapy. Attention is directed to the special problems which arise in the developing countries.
It is intended in a true apprenticeship fashion of pedagogy to provide a manageable, readable and practical account of clinical paediatrics for medical undergraduates, for postgraduates specialising in paediatrics and for general practitioners whose daily work is concerned with care of children in health and sickness. The authors had to be selective in deciding what to exclude in order to keep the book manageable and practical.
We would like to express our immense gratitude to our colleagues who have provided us with help and advice in writing this book. The willingness with which they gave us their time in spite of many other commitments leaves us permanently in their debt.
We are especially grateful to the parents and to the many children and their families who contributed to our knowledge and understanding of paediatrics and willingly gave permission to reproduce photographs of their children. Also a book such as this cannot be written without reproducing material reported in the medical literature. We acknowledge here with gratitude the permission granted free of charge by individual publishers to reproduce material for which they hold the copyright.
Our deepest thanks go to Professor Forrester Cockburn, Professor Dan Young and Professor Robert Carachi, who most kindly passed on to us their rights of the book entitled ‘Children's Medicine and Surgery’ from which some material has been used.
We particularly wish to thank the Hutchison family for allowing us to use the name of the late Professor James Holmes Hutchison, the author of ‘Practical Paediatric Problems’ to enable us to title this book Hutchison's Paediatrics. Even today Hutchison's name is highly respected in the paediatric world.
Finally, we would like to express our thanks to Jean Hyslop, Medical Artist, who created the line drawings and art work and helped to integrate the text with the illustrations.
Krishna M Goel
Devendra K Gupta