Editors Kanu Chatterjee MBBS FRCP (London) FRCP (Edin) FCCP FACC MACP
Clinical Professor of Medicine Division of Cardiology The Carver College of Medicine University of Iowa
Iowa City, Iowa, USA
Emeritus Professor of Medicine University of California
San Francisco, California, USA
Eric J Topol MD FACC
Director, Scripps Translational Science Institute Chief Academic Officer, Scripps Health Vice Chairman, West Wireless Health Institute The Gary and Mary West Chair of Innovative Medicine Professor of Translational Genomics The Scripps Research Institute
La Jolla, California, USA
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This book has been published in good faith that the contents provided by the contributors contained herein are original, and is intended for educational purposes only. While every effort is made to ensure the accuracy of information, the publisher and the editors specifically disclaim any damage, liability, or loss incurred, directly or indirectly, from the use or application of any of the contents of this work. If not specifically stated, all figures and tables are courtesy of the contributors. Where appropriate, the readers should consult with a specialist or contact the manufacturer of the drug or device.
Cardiac Drugs/Editors Kanu Chatterjee, Eric J Topol
First Edition: 2013
9789350258798
Printed at:
5Dedicated to
Our wives
9CONTRIBUTORS
EDITORS
- Kanu Chatterjee MBBS FRCP (London) FRCP (Edin) FCCP FACC MACP
- Clinical Professor of Medicine
- Division of Cardiology
- The Carver College of Medicine
- University of Iowa
- Iowa City, Iowa, USA
- Emeritus Professor of Medicine
- University of California, San Francisco, California, USA
- Eric J Topol MD FACC
- Director, Scripps Translational Science Institute
- Chief Academic Officer, Scripps Health
- Vice-Chairman, West Wireless Health Institute
- The Gary and Mary West Chair of Innovative Medicine
- Professor of Translational Genomics
- The Scripps Research Institute
- La Jolla, California, USA
CONTRIBUTING AUTHORS
- Philip F Binkley MD MPH
- Wilson Professor of Medicine
- College of Medicine, The Ohio State University
- Professor of Epidemiology
- College of Public Health, The Ohio State University
- Vice Chairman for Academic Affairs
- Department of Internal Medicine, The Ohio State University
- Director, Center for FAME
- Associate Dean for Faculty Affairs
- College of Medicine, The Ohio State University
- Columbus, Ohio, USA
- Prakash Deedwania MD FACC FACP FAHA
- Chief of Cardiology Division
- VACCHCS/UMC, UCSF Program at Fresno, Fresno, California, USA
- Professor of Medicine
- UCSF School of Medicine
- San Francisco, California, USA
- Michael E Ernst Pharm D
- Professor (Clinical)
- Department of Pharmacy Practice and Science
- College of Pharmacy
- Department of Family Medicine
- Carver College of Medicine
- The University of Iowa
- Iowa City, Iowa, USA
- Gary S Francis MD
- Professor of Medicine
- Cardiovascular Division
- University of Minnesota
- Minneapolis, Minnesota, USA
- Rakesh Gopinathannair MD MA
- Director
- Cardiac Electrophysiology
- University of Louisville Hospital
- Assistant Professor of Medicine
- Division of Cardiology University of Louisville
- Garrie J Haas MD FACC
- Professor of Medicine
- Division of Cardiovascular Medicine
- Davis Heart and Lung Research Institute
- The Ohio State University of Medicine and Public Health
- Columbus, Ohio, USA
- Sif Hansdottir MD PhD
- Assistant Professor of Medicine
- Division of Pulmonary and Critical Care
- The Carver College of Medicine
- University of Iowa Hospitals and Clinics
- Iowa City, Iowa, USA
- Abdallah Kamouh MD
- Fellow, Advanced Heart Failure and Transplantation
- Cardiovascular Division
- University of Minnesota Medical Center
- Minneapolis, Minnesota, USA
- Wassef Karrowni MD
- Division of Cardiovascular Diseases
- The Carver College of Medicine University of Iowa Hospitals and Clinics
- Iowa City, Iowa, USA
- Ravinder Kumar MD
- Fellow, Cardiovascular Medicine
- Pulmonary Division
- University of Iowa Hospitals and Clinics
- Iowa City, Iowa, USA
- William J Lawton MD
- Associate Professor Emeritus
- Department of Internal Medicine
- Nephrology-Hypertension Division
- Carver College of Medicine
- University of Iowa Hospitals and Clinics
- Iowa City, Iowa, USA
- Carl V Leier MD
- Overstreet Professor of Medicine and Pharmacology, Division of Cardiovascular Medicine, Davis Heart Lung Research Institute
- The Ohio State University of Medicine and Public Health
- Columbus, Ohio, USA
- Brian Olshansky MD FACC FAHA FHRS
- Professor, Division of Cardiovascular Medicine
- University of Iowa Hospitals
- Iowa City, Iowa, USA
- Sundararajan Srikanth MD
- Cardiology Fellow, Department of Medicine
- UCSF Program at Fresno
- San Francisco, California, USA
- Byron Vandenberg MD
- Associate Professor, Division of Cardiovascular Medicine
- Department of Internal Medicine
- University of Iowa Hospitals and Clinics
- Iowa City, Iowa, USA
- Stephen W Waldo MD
- Fellow in Cardiology
- Department of Medicine
- University of California
- San Francisco, California, USA
- Yerem Yeghiazarians MD
- Associate Professor of Medicine
- University of California
The book Cardiac Drugs presents an evidence-based approach towards the pharmacologic agents that are used in various clinical conditions in cardiovascular medicine.
The classes of drugs, such as renin-angiotensin-aldosterone blocking drugs, positive inotropic drugs, diuretics, and antihypertensive drugs are discussed in great details with their pharmacokinetics, pharmacodynamics, indications, contraindications, and doses. Drugs for heart failure, acute coronary syndromes, and pulmonary hypertension are also discussed similarly. Pharmacologic agents, which are in development for various clinical syndromes are also discussed. The unique feature of this book is the detailed discussion on the guidelines of the American College of Cardiology/American Heart Association for the use of pharmacologic agents in various clinical conditions.
Kanu Chatterjee
13ACKNOWLEDGMENTS
We are very grateful to all the contributing authors. Their expertise is very much appreciated. We also acknowledge the help of our all administrative assistants and colleagues.
We sincerely thank to Shri Jitendar P Vij (Group Chairman), Mr Ankit Vij (Managing Director), Mr Tarun Duneja (Director-Publishing), Dr Neeraj Choudhary, Ms Shaila Prashar, and the expert team of M/s Jaypee Brothers Medical Publishers (P) Ltd., New Delhi, India for their concerted efforts. Without their hard work, this book could not have been published.